• Title/Summary/Keyword: the 2000s

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Climatic Characteristics of August and Summer of 2007 and Long Term Trend of August and Summer Climate (한반도의 2007년 8월과 2007년 여름의 기후특성 및 8월과 여름의 장기 기후변화)

  • Shin, Im Chul;Kim, Tae Ryong;Lee, Eun-Jung;Kim, Eun-Hee;Kim, Eun Suk;Park, Yeon Ok;Bae, Sun-Hee;Yi, Hi-Il
    • Atmosphere
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    • v.17 no.4
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    • pp.471-481
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    • 2007
  • Temperature and precipitation, particularly August and summer, in the Korean peninsular are analyzed. The analyzed period is 1973-2007 for the Korean peninsular (that is, 60 meteorological station average). In addition, 100 year record (1908-2007) of temperature and precipitation in Seoul are also analyzed. Results indicate that the temperatures (mean, maximun, and minimum) of August and summer of 2007, both in Korean peninsular and Seoul, are higher than normal. The increasing rate of minimum temperature for the August and summer during the period from 1973 to 2007 shows greater than the mean and maximum temperature both in Korean peninsular and Seoul due to the global warming and urbanization. Number of tropical night days, defined by the days with above $25^{\circ}C$ in minimum temperature, shows increasing trend both in August and summer from 1973 to 2007 due to the combination effect of the global warming and urbanization. The amount of precipitation, both in August and summer, for Korean peninsular and Seoul shows increasing trend from 1973 to 2007, and 1908 to 2007, respectively. Amount of precipitation and rainy days, both August and summer, during 2000s show greater than those of the 1970s both in Korean peninsular and Seoul. Extreme rainy days (greater than 120mm/day, greater than 80mm/day, greater than 30mm in any 1-hour period and greater than 10mm in any 10-minute period) show increasing trend from 1973 to 2007 for both in August and in summer.

In Vitro Development of Bovine Nuclear Transfer Embryos Reconstructed with Fetal Fibroblasts (태아 섬유아세포로 재구성된 핵치환 소 수정란의 체외발달)

  • Koo, D.B.;Choi, Y.H.;Park, J.S.;Kim, H.N.;Kang, Y.K.;Lee, C.S.;Han, Y.M.;Park, H.D.;Lee, K.K.
    • Korean Journal of Animal Reproduction
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    • v.24 no.4
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    • pp.407-417
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    • 2000
  • The present study was to examine effects of various electrical stimulus treatments used for electro-fusion on the preimplantation development of bovine nuclear transfer (NT) embryos with fetal fibroblast cells. Fetal fibroblast cells were isolated from one fetus at day 45 of gestation in Holstein cow, and passaged 3 to 4 times before being transferred into enucleated oocytes. Single fibroblast cells were individually placed into the perivitelline space of enucleated oocytes by using a micromanipulator. At first, the fusion and developmental rates of reconstructed oocytes were compared between different electric stimulation conditions. When fusion of the reconstructed oocyte was induced by different electric pulse periods (15, 30 and 45 $\mu$sec) at a DC pulse of 1.8 kV/cm, 15 (45.5%, 120/264) or 30 $\mu$ sec group (43.9%, 106/241) showed a higher fusion rate than 45 $\mu$sec group (23.2%, 58/250, P<0.05). However, no difference was detected in the development rate of the fused oocytes to blastocysts between groups. Next experiment was to examine the effects of different electrical field strengths (1.5, 1.8 and 2.1 kV/cm) for 15 $\mu$sec at electrofusion on in vitro development of the NT embryos. As results, there was no difference in the fusion and developmental rates of the NT embryos between electrical strength (P>0.05). Finally, developmental competence of bovine NT embryos with somatic cells was compared with IVF-derived embryos. Of enucleated oocytes fused with fibroblast cells, 27.4% (75/274) developed to the blastocyst stage, which is similar to that (24.5%, 58/237) of IVF-derived embryos. However, mean nuclei number of NT blastocysts was smaller than that of IVF-derived blastocysts. Thus, we have established an optimal condition (1.8 kV/cm, 15 $\mu$sec) for electric fusion of bovine NT oocytes with somatic cells. The present study indicates that bovine reconstructed embryos with somatic cells normally develop to blastocyst stage in vitro, although having smaller nuclei numbers of blastocysts as compared to IVF-derived embryos.

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Clinical Features of Acute Nonspecific Mesenteric Lymphadenitis and Factors for Differential Diagnosis with Acute Appendicitis (급성 비특이성 장간막 림프절염의 임상 소견과 급성 충수돌기염과의 감별 인자)

  • Shin, Kyung Hwa;Kim, Gab Cheol;Lee, Jung Kwon;Lee, Young Hwan;Kam, Sin;Hwang, Jin Bok
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.7 no.1
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    • pp.31-39
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    • 2004
  • Purpose: Although acute nonspecific mesenteric lymphadenitis (ANML) is probably common cause of abdominal pain in children, which can be severe enough to be an abdominal emergency, the clinical features of mesenteric lymphadenitis are not clear. Also, a differential diagnosis with acute appendicitis (APPE) is indispensable to avoid serious complications. The clinical features of ANML were determined, and the risk factors for differential diagnosis with APPE were analyzed. Methods: Between November 2000 and May 2001, data from 26 patients (aged 1 to 11 years) with ANML and 21 patients (aged 2 to 13 years) with APPE were reviewed. ANML was defined as a cluster of five or more lymph nodes measuring 10 mm or greater in their longitudinal diameter in the right lower quadrant (RLQ) without an identifiable specific inflammatory process on the ultrasonographic examination. There were risk factors on patient's history, physical examination, and laboratory examination; the location of abdominal pain, abdominal rigidity, rebound tenderness, fever, nocturnal pain, the vomiting intensity, the diarrhea intensity, the symptom duration, and the peripheral blood leukocytes count. Results: Of the 26 ANML patients and 21 APPE patients, abdominal pain was noted on periumbilical (76.9% vs 14.2%), on RLQ (11.5% vs 71.4%), with abdomen rigidity (7.6% vs 80.9%), with rebound tenderness (0.0% vs 76.1%)(p<0.05), in the lower abdomen (11.5% vs 14.2%), and at night (80.8% vs 100.0%) (p>0.05). The clinical symptoms were vomiting (38.4% vs 90.4%), the vomiting intensity ($1.5{\pm}0.7$ [1~3]/day vs $4.5{\pm}2.9$ [1~10]/day), diarrhea (65.3% vs 28.5%) (p<0.05), and fever (61.5% vs 76.2%)(p>0.05). The period to the subsidence of abdominal pain in the ANMA patients was $2.5{\pm}0.5$ (2~3) days. The laboratory data showed a significant difference in the peripheral blood leukocytes count ($8,403{\pm}1,737[5,900{\sim}12,300]/mm^3\;vs\;15,471{\pm}3,749[5,400{\sim}20,800]/mm^3$)(p<0.05). Discriminant analysis between ANML and APPE showed that the independent discriminant factors were a vomiting intensity and the peripheral blood leukocytes count and the discriminant power was 95.7%. Conclusion: The clinical characteristics of ANML were abrupt onset of periumbilical pain without rigidity or rebound tenderness, a mild vomiting intensity, normal peripheral leukocytes count, and relatively short clinical course. If the abdominal pain persist for more than 3 days, and/or the vomiting intensity is more than 3 times/day, and/or the peripheral leukocytes count is over $13,500/mm^3$, abdominal ultrasonography is recommended to rule out APPE.

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Clinical Analysis of Arteriovenous Fistula in Chronic Renal Failure Patients (만성 신부전 환자에서의 동정맥루 조성술의 임상고찰)

  • Song Chang-Min;Ahn Jae-Bum;Kim In-Sub;Kim Woo-Sik;Shin Yong-Chul;Yoo Hwan-Kuk;Kim Byung-Yul
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.692-698
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    • 2006
  • Background: Owing to the fact that the average life span has increased and the progress in medical science has been made, the number of patients with chronic renal failure (CRF) who have to take hemodialysis (HD) has been going up gradually. Accordingly, it is considered to be as a significant issue to obtain blood vessels which can be used repetitively and supply enough blood flows. Therefore, there have been various kinds of study on an inosculation rate andfactors influencing it following an arteriovenous fistula (AV fistula) and lots of studies are ongoing for the purpose of escalating the inosculation rate. The authors analyzed the effects of short-term result, age, sex, diabetes and hypertension on arteriovenous inosculations in 134 anatomical snuffbox operated subjects among the patients who have taken an AV fistula at this center. Material and Method: Based on 134 patients who underwent an AV fistula at the department of thoracic surgery of this center from July, 2000 to May, 2004, the difference in arteriovenous inosculation rate was compared and analyzed depending or age (discriminated by 65-year-old), sex and the condition of the presence or absence of diabetes and hypertension. Correlation analyses were conducted for each parameter and statistical tests were performed by using SPSS for windows Release 11.0.1, which were determined to be statistically significant if p value was below 0.05. Result: The total number of operations was 169 including 35 of re-operations. The male/female rate was 70 : 64 (52% : 48%). The average age was $56.3{\pm}12.26$ years and there were 33 (24%) old aged patients above 65-year-old; there were 103 (71%) patients with hypertension and 90 (67%) patients with diabetes. Overall arteriovenous inosculation rate was $93{\pm}2.4%,\;91{\pm}2.7%,\;89{\pm}3.0%$ at 6, 12, 24 months, respectively. The arteriovenous inosculation rate of above 65-year-old patient group was $85{\pm}4.8%,\;80{\pm}5.8%,\;80{\pm}5.8%$ and below 64-year-old patient group's was $85{\pm}4.8%,\;80{\pm}5.8%,\;80{\pm}5.8%$ at given time points, respectively, which showed higher inosculation rate in below 64-year-old patient group with a statistical significance (p=0.0034). However, no statistical significance was found between the patients with hypertension and diabetes and the patients with no complication. In addition, there was no statistical significance in inosculation rate between male and female. Conclusion: The arteriovenous inosculation ratewas higher in the treated patient below 64-year-old than in the treated patient above 65-year-old. Thus it is advantageous for increase in long-term inosculation rate to obtain hemodialysis routes at an early age. The conditions of sex and the presence or absence of diabetes and hyper- tension do not make statistically significant effect on the arteriovenous inosculation rate.

Seed Coating Material and Seed Size Effects on Agronomic Characteristics of Over Sown Pasture Species (피복재료 및 종자의 크기가 겉뿌림 목초의 생육특성에 미치는 영향)

  • 김종관;권찬호;김동암
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.20 no.1
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    • pp.67-76
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    • 2000
  • An experiment was conducted to evaluate the effects of lime, zeolite, and rock phosphate as coating materials and coated seed size on germination, establishment, and early growth of pasture species at the experimental livestock farm, Yonam College of Agriculture in 1997. Germinating energy and germination of coated tall fescue and orchardgrass seeds were lower than those of non-coated seeds. Coated seed of tall fescue with 70% lime and 15% rock phosphate was the best in germination. The germination of small size seed (< ${\varnothing}2$ mm) was better than those of medium (> ${\varnothing}2$ mm and < ${\varnothing}2$ mm) and large size seeds (> ${\varnothing}2$ mm). Germination of coated orchardgrass seed with 55% lime and 30% rock phosphate treatment was higher than that of other coated seeds, and germination of small size seed was higher than those of medium and large size seeds (p<0.05). Germination energy and germination of coated alfalfa and birdsfoot trefoil seeds were lower than those of non-coated seeds. Germination of coated alfalfa seed with 70% lime and 15% rock phosphate, and 45% lime and 55% rock phosphate was higher compared with other coated seeds. Germination of medium size seed was higher than those of small and large size seeds (p<0.05). Among coated birdsfoot trefoil seed, 45% lime and 40% rock phosphate treatment resulted in higher germinating energy and germination than other treatments. There was no significant difference in establishment and early growth of coated tall fescue and orchardgrass seeds. However, tall fescue and orchardgrass coated with 45 % lime and 40% phosphate rock showed higher establishment and early growth. There was also no significant difference in establishment and early growth of coated alfalfa among the treatments. Among coated treatments, establishment and early growth of alfalfa coated with 75% lime and 10% rock phosphate were the highest and showed 46.4% and $72.6\;g/\textrm{m}^2$, respectively. Establishment and early growth of coated birdsfoot trefoil with 55% lime and 30% rock phosphate were the highest among coated birdsfoot trefoil seed (p<0.05) and recorded 46.4% and $44.6\;g/\textrm{m}^2$, respectively. Results of this study indicate that the germination of coated grass and legume seed may be improved by increasing the percentage of rock phosphate and decreasing that of lime. With regard to seed size, the germination of pasture species with small seed size (< ${\varnothing}2$ mm) may be better than medium and large size seeds except alfalfa. Establishment and early growth of grasses can be also improved by increasing the percentage of rock phosphate and decreasing that of lime.

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Solution Structure of 21-Residue Peptide (Asp 84-Leu 104), Functional Site derived from $p16^{INK4A}$ ($p16^{INK4A}$ 단백질 활성부위(Asp 84-Leu 104)의 용액상 구조)

  • Lee, Ho-Jin;Ahn, In-Ae;Ro, Seonggu;Choi, Young-Sang;Yoon, Chang No;Lee, Kang-Bong
    • Analytical Science and Technology
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    • v.13 no.4
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    • pp.494-503
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    • 2000
  • A 21-residue peptide corresponding to amino acids 84-104 of $p16^{INK4A}$, the tumor suppressor, has been synthesized and its structure was studied by Circular Dichroism, $^1H$ NMR spectroscopy and molecular modeling. A p16-derived peptide (84-104 amino acids) forming stable complex with CDK4 and CDK6 inhibits the ability of CDK4/6 to phosphorylate pRb in vitro, and blocks cell-cycle progression through G1/S phase as shown in the function of the full-length p16. Its NMR spectral data including NOEs, $^3J_{NH-H{\alpha}}$ coupling constants, $C_{\alpha}H$ chemical shift, the average amplitude of amide chemical shift oscillation and temperature coefficients indicate that the secondary structure of a p16-derived peptide is similar to that of the same region of full-length p16, which consists of helix-turn-helix structure. The 3-D distance geometry structure based on NOE-hased distance and torsion angle restraints is characterized by ${\gamma}$-turn conformation between residues $Gly^{89}-Leu^{91}$(${\varphi}_{i+1}=-79.8^{\circ}$, ${\varphi}_{i+1}=60.2^{\circ}$) as evidenced in a single crystal structure for the corresponding region of p18 or p19, but is undefined at both the N and C termini. This compact and rigid ${\gamma}$-turn region is considered to stabilize the structure of p16-derived peptide and serve as a site recognizing cyelin dependent kinase, and this well-defined ${\gamma}$-turn structure could be utilized for the design of anti-cancer drug candidates.

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A study of intakes of vegetables in Korea (한국(韓國)의 채소(菜蔬) 음식(飮食) 문화(文化))

  • Cho, Mi-Sook
    • Journal of the Korean Society of Food Culture
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    • v.18 no.6
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    • pp.601-612
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    • 2003
  • In Korean history, vegetables were the major side dishes of meals and originally korean diets were based on vegetables. But recently people prefer meat dishes rather than vegetables and traditional vegetable cooking seems to be disappeared. So it is needed to be positioning the importance of vegetables in food culture of Korean. In present study, history of vegetable eating was reviewed and recent consumption pattern were analyzed. 1. Since the era of the three Kingdom's and Koryo dynasty, the kinds of vegetables varied and at Chosun Dynasty people used similar kinds of vegetables as nowadays except a few things. A Garlic and mug wort had been used from the age of tribes to present and an egg, apple, cucumber, lettuce from the three Kingdom and a bamboo sprout, a taro, a burdock, a radish, a turnip, a stone-leek, a scallion, a Chinese cabbage, a marsh mallow, a spinach and a crown daisy from Koryo Dynasty and a pepper, a pumpkin, a tomato, a cabbage, a salary, a kale, a turnip and a beet from Chosun Dynasty to present. A guard, a water shield plant, a yam and wild plants would have been used before but they would not use any more. 2. Current vegetable consumptions of Korean is 232.2kg/person/yr and comparing with world mean consumption(101.9kg), Koreans still eat the largest amount of vegetables than any other countries and among Asian countries, Koreans consume more vegetables than China(203.5kg) and Japanese people(111.6kg) do. 3.The most frequently consumed vegetables were vegetables for seasonings such as a garlic or stone-leek and for kimchi such as a Chinese cabbage, radish, and carrot. But from data of Korean National Health and Nutrition Survey(2001), kinds of vegetables which people had were only 72 items showing that the kinds of vegetables were limited. 4. A lot of wild plants that would have been used for famine relief are now disappeared and on the other hand, it is increasing of some new and foreign vegetables and herbs. Cooking methods and intake pattern of vegetables are changed and varied so a traditional cooking method such as namuel is less preferred than before. But vegetable wrapping and green vegetable juice, eating uncooked vegetables(sang-sik) are very popular.

Rheological Properties of ${\beta}-Glucan$ Isolated from Non-waxy and Waxy Barley (메성 및 찰성보리 ${\beta}-Glucan$의 리올로지 특성)

  • Choi, Hee-Don;Park, Yong-Gon;Jang, Eun-Hee;Seog, Ho-Moon;Lee, Cherl-Ho
    • Korean Journal of Food Science and Technology
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    • v.32 no.3
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    • pp.590-597
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    • 2000
  • The rheological properties of ${\beta}-glucans$ isolated from non-waxy and waxy barley were investigated. ${\beta}-Glucan$ solutions showed pseudoplastic properties and their behaviors were explained by applying Power law model in the range of concentrations$(1{\sim}4%)$ and temperatures$(20{\sim}65^{\circ}C)$. The effects of temperature and concentration on the apparent viscosity at $700\;s^{-1}$ shear rate were examined by applying Arrhenius equation and power law equation, and their effect was more pronounced in waxy ${\beta}-glucan$ solutions. The activation energy for flow of ${\beta}-glucan$ solutions decreased with the increase of concentration, and the concentration-dependent constant A increased with the increase of temperature. The intrinsic viscosity of waxy ${\beta}-glucan$ was higher than that of non-waxy ${\beta}-glucan$. The transition from dilute to concentrate region occurred at a critical coil overlap parameter $C^*[{\eta}]=0.02.$ The slopes of non-waxy and waxy ${\beta}-glucan$ at $C[{\eta}] were similar, but the slope of waxy ${\beta}-glucan$ at $C[{\eta}]>C^*[{\eta}]$ was higher than that of non-waxy ${\beta}-glucan$. Dynamic viscoelasticity measurement showed that cross-over happened, and storage modulus was higher than loss modulus at frequency range above cross-over. ${\beta}-Glucan$ solutions formed weak gels after stored for 24 hr.

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Development of New BNR Process Using Fixed-Biofilm to Retrofit the Existing Sewage Treatment Plant (고정생물막을 이용한 기존 하수처리장의 생물학적 영양염 제커 신공정개발)

  • Kim, Mi-Hwa;Lee, Ji-Hyung;Chun, Yang-Kun;Park, Tae-Joo
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.6
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    • pp.1093-1101
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    • 2000
  • The object of this study was to develop new BNR process using fixed-biofilm which could be applied to retrofit the existing wastewater treatment plant or to introduce as tertiary treatment plant. To achieve complete denitrification from typical raw sewage in Korea, external carbon source must be supplied because $SCOD_{cr}/T-N(NH_4{^+}-N+NOx-N)$of raw sewage was lower than other countries. In this study, the ratio of $SCOD_{cr}/NH_4{^+}-N$ was 2.49 and the influent $NH_4{^+}$-N concentration during the experimental period was varied from 25 to 37 mg/L. To enhance nitrogen removal from the sewage, the two processes using fixed biofilm were adopted as R-Hanoxic/mid.settler/aerobic/anoxic/ aerobic) and R-2(aerobic/mid.settlerlanoxic/anoxic/aerobic), respectively. In the comparison of $NH_4{^+}$-N, T-N effluent quality and T-N removal efficiency in both processes without external carbon source, R-1 process was better than R-2 process for nitrogen removal from raw sewage. With respect to $SCOD_{cr}$/NOx-N ratio and total nitrogen removal in each anoxic reactor of two processes, R-1's was more effective than R-2's for distributing organic matters of raw sewage. In the both processes using fixed biofilm, the amount of required alkalinity to remove unit $NH_4{^+}$-N were 5.18 and 5.76($g{\cdot}CaCO_3/g{\cdot}NH_4{^+}-N_{removed}$), respectively and were lower than activated sludge BNR process(7.14).

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Development of Drawing & Specification Management System Using 3D Object-based Product Model (3차원 객체기반 모델을 이용한 설계도면 및 시방서관리 시스템 구축)

  • Kim Hyun-nam;Wang Il-kook;Chin Sang-yoon
    • Korean Journal of Construction Engineering and Management
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    • v.1 no.3 s.3
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    • pp.124-134
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    • 2000
  • In construction projects, the design information, which should contain accurate product information in a systematic way, needs to be applicable through the life-cycle of projects. However, paper-based 2D drawings and relevant documents has difficulties in communicating and sharing the owner's and architect's intention and requirement effectively and building a corporate knowledge base through on-going projects due to Tack of interoperability between specific task or function-oriented software and handling massive information. Meanwhile, computer and information technologies are being developed so rapidly that the practitioners are even hard to adapt them into the industry efficiently. 3D modeling capabilities in CAD systems are enormously developed and enables users to associate 3D models with other relevant information. However, this still requires a great deal of efforts and costs to have all the design information represented in CAD system, and the sophisticated system is difficult to manage. This research focuses on the transition period from 2D-based design Information management to 3D-based, which means co-existence of 2D and 3D-based management. This research proposes a model of a compound system of 2D and 3D-based CAD system which presents the general design information using 3D model integrating with 2D CAD drawings for detailed design information. This research developed an integrated information management system for design and specification by associating 2D drawings and 3D models, where 2D drawings represents detailed design and parts that are hard to express in 3D objects. To do this, related management processes was analyzed to build an information model which in turn became the basis of the integrated information management system.

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