• The Korean Journal of Applied Statistics
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• v.25 no.1
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• pp.139-152
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• 2012

The result of the analysis of a population pharmacokinetic model can directly influence the decision of the dose level applied to the targeted patients. Therefore the validation procedure of the final model is very important in this area. This paper reviews the validation methods of population pharmacokinetic models from a statistical viewpoint. In addition, the whole procedure of the analysis of population pharmacokinetics, from the base model to the final model (that includes various validation procedures for the final model) is tested with real clinical data.

• Transactions of Materials Processing
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• v.4 no.3
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• pp.245-256
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• 1995

SMC(Sheet Molding Compound), a thermoset composite material which consists of unsaturated polyester resin, fiberglass strands, fillers, and various chemical additives for curing agent, has been widely used in fabrication of structural components. The mechanical properties of molded SMS parts are strongly dependent on material flow results during compression molding process, while such flow in molds is affected by material characteristics. For numerical simulation of SMC molding process, estimation of material property of SMC must be accomplished. In this study, flow resistance of SMC was estimated through a simple compression test using a lubricant with grease oil under the constant strain rate condition at various temperatures and the result was compared with other material data available in the literature. The accuracy of the experimentally determined flow resistance was tested by finite element analyses of compression molding of SMC. Simulation results were compared with experimental results under the plane strain condition.

• Journal of Welding and Joining
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• v.12 no.3
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• pp.48-55
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• 1994

In this experiment, to find optimum brazing conditions for Cu/Stainless Steel brazing using filler metals of Ag-Cu-Zn-Cd system, first of all spreading ratio was tested on 304 stainless Steel and low carbon steel. And then shear test of brazed joint was executed. As the result of that, the shear strengths of brazed joints were the range of 60-90 MPa. Through microstructure analysis for brazed interface layer, We found as follows. Firstly interface layer increased as time increased. Secondly continuous layer of Ag-Cd compound was observed along the side of stainless steel. Also by means of EDS analysis for fracture surface, ductile fracture was occurred and precipitates on the fracture surface were found to include Cr, Mn, Si in Ag-rich phase.

• Journal of Welding and Joining
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• v.17 no.5
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• pp.89-96
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• 1999

The base metal and weld metal of alloy designed austenitic stainless steels were electrochemically tested in artificial sea water. Pitting resistance of 14 different stainless steels was evaluated by measuring pitting potential. The effect of alloy element to pitting potential was evaluated by changing chromium, nickel, sulfur content. The site of pitting initiation was observed by optical microscope. As a result of electrochemical test, pitting resistance of weld metal was higher than base metal, and rapidly cooled weld metal has higher pitting potential than slowly cooled weld metal. In case of primary δ-ferrite solidification, pitting potential was increased, but residual δ-ferrite was detrimental to pitting resistance. Chromium was more effective to pitting resistance than nickel, and sulfur was very detrimental element to pitting resistance.

• Parasites, Hosts and Diseases
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• v.51 no.3
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• pp.375-377
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• 2013

In the present study, we first report the seroprevalence of Dirofilaria immitis in dogs in Shenyang, northeastern China. Sera from 528 randomly selected dogs were examined for D. immitis antigen using SNAP$^{(R)}$4Dx test kit; 12.7% tested showed seropositive. No significant difference of infection was observed in different genders and breeds (P>0.05), but the difference was significant in different age groups and rearing conditions (P<0.05). The result suggested that the risk of exposure to D. immitis in dogs is high in Shenyang, and should be given attention.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1996.11a
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• pp.560-564
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• 1996

In recently, annealing process of cold rolled sheet tend to change to continuous annealing process for improving qualify, saving yield. In the meantime as demand for various kind and small lot of products has been increasing, batch annealing has been appreciated for its small restriction for the operation. So, we tested on the effect for a hydrogen contents of atmospheric gas at annealing furnace. As a result of several investigation. We confirmed for the following characteristics ; improved productivity, uniform heating, improved surface quality, saving energy. Therefore, the use of hydrogen instead of nitrogen as the protective gas, combined with high convection in batch annealing furnaces, has shown that considerable increases in furnace output and material quality are attainable. Owing to the low density, high diffusion and reducing character of hydrogen, a better transfer resulting in uniform material temperatures and improved coil surfaces can be achieved.

• Journal of the Korean Society for Precision Engineering
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• v.20 no.4
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• pp.112-117
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• 2003

This paper deals with the problem of synthesis of the 3-dimensional Grasp Planning. In previous studies the genetic algorithm has been used to find optimal grasping points, but it had a limitation such as the determination time of grasping points was so long. To overcome this limitation we proposed a new algorithm which employs the Neural Network. In the Neural network we chose input parameters based on the shape of the object and output parameters resulted from optimization with the GA method. In this study the GRNN method is employed, it has been trained by the result value of optimization method and it has been tested by known object. The algorithm is verified by computer simulation.

• Korean Journal of Pharmacognosy
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• v.32 no.2 s.125
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• pp.140-144
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• 2001

The composition of essential oils in the leaves of three cultivars (Ban-Chung-Gat, Chung-Gat and Dolsan-Gat) of Brassica juncea L. were analyzed and their antifungal activity were investigated in this study. Allyl isothiocyanate, 2-phenyl ethyl isothiocyanate, 4-isothiocyanato-1-butene, 5-methyl isothiazole, benzene acetaldehyde, benzene propane nitrile and beta-ionone have been identified in all of the experimented oils. The main component of the oils from Ban-Chung-Gat and Chung-Gat was 2-phenyl ethyl isothiocyanate while allyl isothiocyanate was the representing compound in the oil of Dolsan-Gat. The antifungal activities of the oils were tested by micro broth dilution method and disc diffusion method. As the result the oils exhibited significant inhibiting activities against Aspergillus niger, A. flavus, Trichoderma viride, Candida albicans, C. utilis, C. tropicalis, Cryptococcus neoformans, Trichosporon mucoides, Trichophyton tonsurans and Geotrichum capitatum.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.8
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• pp.1885-1896
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• 1996

This paper describes the implementation of the AVT(Automatic video Tracker) using ASIC. The basic tracking algorithm is based on the spatio-temporal gradient method, and adaptive window sizing, track state decision algorithm were also realized. Newly developed ASIC performs recursive image filtering, extraction of spatio-temporal gradient/gradient functions of image in field rate. Using the FPGA/ASIC, the tracker was simply realized in one board type which can be easily applied to various image system. We conformed ASIC operation by computer simulation and tested the system in real tracking situations. From the result, the system can track the moving target which has a velocity of 2-3 pixel/field and a size of varying from 2 to 128 pixes. Also fast refresh rateof motion estimation(60Hz) improves the characteristics of servoing system which forms feedback loop with the tracker.

• Journal of the Korean Society for Precision Engineering
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• v.16 no.8
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• pp.100-105
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• 1999

This work analyses the effects of electrical conductivities of dielectric and cobalt amount on output parameters such as metal removal rate and the surface roughness value of cemented carbides cut by wire electrical discharge machining(W-EDM). Especially, the cracking behaviour of W-EDM machined surface and optimal machining condition of three kinds of cemented carbides, which have different chemical composition of tungsten carbide and cobalt are also tested. Experimental result shows that increases in cobalt content and electrical conductivity of the dielectric affect the metal removal rate and substantially worsen the final surface quality as a greater quantity of solidified metal deposits on the eroded surface.