• Journal of Pharmaceutical Investigation
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• v.37 no.2
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• pp.79-84
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• 2007

This study was aimed to establish analytical method of Bi to develop a guideline of the bioequivalence test of tripotassium dicitrato bismuthate (TDB). For this purpose, a simple, specific and sensitive inductively coupled plasma-mass spectrometry (ICP/MS) method were developed and validated in human plasma. Various concentrations of bismuth standard solution (0-25ng/mL) were prepared with distilled water and human blank plasma. To 10mL of the volumetric flasks, 2mL of blank plasma was added with 8ml of distilled water. Bi standard solution was added to prepare the calibration samples and injected into ICP-MS. The plasma samples obtained from volunteers given 3 tablets of bismuth (total 900mg as TDB) were analyzed as described above. As a result, the coefficients of variation were <20% in quantitation limit (0.2 ng/mL) and <15% at the rest of concentrations. The stability test by repeated freezing-thawing cycles showed that the samples were stable only for 24hr. The stability tested for samples with a short-term period of storage at room temperature and pre-treatment prior to the analysis showed very stable over 24hr. In 8 healthy Korean subjects received Denol tablets at the dose of 900mg bismuth, AUC, $C_{max},\;T_{max}$ and half-life $(t_{1/2})$ were determined to be $198.33{\pm}173.78 ng{\cdot}hr/mL,\;64.48{\pm}27.06 ng/mL,\;0.52{\pm}0.21 hr,\;and\;5.15{\pm}2.67 hr$, respectively, from the plasma bismuth concentration-time curves. In conclusion, the method was suitable for the determination of bismuth in human plasma samples and could be applied to bioequivalence test of bismuth tablet.

• Journal of Korean Physical Therapy Science
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• v.8 no.2
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• pp.1023-1032
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• 2001

The muscles relating to movement of painful low back was analyzed kinematically, by method of applying elastic tapes and putting non-elastic tapes on muscles involving those movements which cause pain and limitation of range of motion (ROM) in low back and trunk. Taping therapy which is effective for improvement of painful low back and which is supposed to facilitate the total and continual movement based on the postural reflexes will be presented in this paper. Fifty cases who had painful low back were investigated. Patients with painful low back were at first asked pain point and direction of painful movement, and then tested the muscles which are cause of those pain and limited motion. Before attaching tape, all subjects were divided into two groups, flexor pattern and extensor pattern, according to direction of increasing pain. Elastic tapes were applied from origin to insertion of objective muscles and non-elastic tapes were put on effective points of the muscles which were associated with respect to pain and limited ROM. As a result of this study, all subjects with low back pain significantly improved in pain and ROM at the low back. The longest treatment duration group for the low back pain cases was herniated lumbar disc(10.4 days) group. Low back pain have been treated by so many ways. muscles factor should be emphasized to be distinguish1y important to reduce low back pain. The muscles relating to make directly painful motion in low back and trunk should be confirmed by means of taping and painful motion should be analyzed by point of view of postural reflexes.

• Applied Biological Chemistry
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• v.51 no.3
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• pp.228-232
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• 2008

In the present study, we investigated the glutathione S-transferase (GST) induction of medicinal plants using a cultured PC12 cells. The methanol extracts of Dendrobium nobile Lindley, Schizonepeta tenuifolia Briquet, Glycyrrhiza uralensis Fischer, Paenoia lactiflora Pall were tested. As the result, exposure of PC12 cells to G. uralensis resulted in the significant induction of GST. On the continuous experiment, G. uralensis was extracted with methanol, ethanol, and acetone. Among these extracts, methanol extracts showed the highest GST induction. The methanol extracts were further fractionated with hexane, diethyl ether, ethyl acetate, and water layer according to the degree of polarity. The diethyl ether layer showed the highest exhibited GST induction on PC12 cells. Based on these results suggest that the extracts of G. uralensis can be applicable for the development of a new antioxidant agent.

• Journal of The Korean Society of Agricultural Engineers
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• v.55 no.2
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• pp.59-64
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• 2013

The present study is to evaluate physical and mechanical properties of porous concrete having non cement that mainly causes carbon emission. This study aims to explore eco-friendly concrete technology capable of reducing the amount of carbon emission due to the use of normal cement by substituting it with non cement porous concrete to which alkali-activator and blast-furnace slag powder are impregnated. As experimental variables, 5 %, 6 %, 7 %, 8 %, 9 % and 10 % of alkali-activator were substituted as binders and applied. Testing evaluated in this study were pH value, void ratio, compressive strength and residual compressive strength shown after being immersed in $H_2SO_4$ solution and $Na_2SO_4$ solution. The test results were compared with those tested with the use of porous concrete to which 400 $kg/m^3$ of unit cement amount was applied as binder. In consequence, it was concluded that; as for pH value, it was decreased than was the case in which cement was used, but increased with the more the use of alkali activator; as for void ratio and compressive strength, the mix proportion in which 9 % and 10 % of alkali activator were applied in terms of substitution ratio showed the result similar to the mixture in which 400 $kg/m^3$ of unit cement ratio was applied; and, as for residual compressive strength in the case of being immersed in $H_2SO_4$ solution and $Na_2SO_4$ solution, the compressive strength was increased, thus leading to improved chemical resistance.

• Analytical Science and Technology
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• v.15 no.1
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• pp.7-14
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• 2002

Laser ablation ion trap mass spectrometry (LAITMS) was developed for the analysis of metal and ceramic samples. For this study, XeCl excimer laser (308 nm) was used for ablating the samples and ITMS was used as a detector. Samples were introduced from outside of a ring electrode and this way of sample introduction was very effective for solid samples when laser ablation was employed. Helium gas was used as a buffer gas, and its effect on sensitivity and some parameters (buffer gas pressure, ion storage time, and cut-off RF voltage) were studied. The optimized conditions were $1{\times}10^{-4}$ Torr of buffer gas pressure, 100 ms of ion storage time and $1150V_{p-p}$ of cut-off RF voltage. From that results, copper (Cu) and molybdenum (Mo) metals were tested with LAITMS and the mass spectra of these pure metals were compared with the natural abundance of isotope ratio. We also examined ceramic samples ($Al_2O_3$, $ZrO_2$) and represented the result of elemental analysis.

• Korean Journal of Environmental Agriculture
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• v.35 no.2
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• pp.97-103
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• 2016

BACKGROUND: Clay mineral is well known to improve physico-chemical of soil. The objective of this study was to investigate the growth characteristics and inorganic nutrient contents of crops with application levels of phyllite.METHODS AND RESULTS: Both young radish and lettuce were selected as target crops for this study. The experiment was conducted in a wagner pot(1/5000a) in glass house at Sunchon National University. Treatment conditions were divided P0NPK(No phyllite + NPK), P5NPK(phyllite 5 Mg/ha + NPK), P10NPK(phyllite 10 Mg/ha + NPK) and P15NPK(phyllite 15 Mg/ha + NPK) by crops, respectively. Bulk density and porosity of soil in control without treatment conditions were ranged from 1.02 ∼1.04 g/cm³ and 56.5∼57.0%, respectively, and those for treatments with phyllite were in the ranged from 0.94∼1.00 g/cm³ and 58.4∼63.5%, respectively. Dry weights of young radish and lettuce were higher in P15NPK treatment than those in other treatments. The amounts of T-N, T-P and K uptake in young radish with phyllite application treatments were increased 36∼115, 18∼67 and 20∼76% than without phyllite application treatment, respectively. In lettuce treatments, amounts of T-N, T-P and K uptake were intended to all tested treatments similar with result of young radish treatment.CONCLUSION: Therefore, these results confirm that phyllite application to the soil improves physico-chemical of soil in addition to improving growth of young radish and lettuce.

• Journal of Energy Engineering
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• v.24 no.3
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• pp.1-5
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• 2015

This study is to investigate the effect of torrefaction on enzymatic hydrolysis of lignocellulosic biomass for bio-ethanol production. As a pretreatment, the torrefaction of lignocellulosic biomass was conducted in temperature of $250{\sim}350^{\circ}C$ in the absence of oxygen. Tween-80, nonionic surfactant, was tested to enhance saccharification efficiency by coping with hydrophobicity resulted from torrefaction. As a result, the glucose production from enzymatic hydrolysis of biomass pretreated by torrefaction was greater than that obtained from the non-pretreated biomass. Sugar conversion was higher when the biomass was saccharified with addition of tween-80. It was found that torrefaction can be applied as a preptreatment for lignocellulosic biomass and tween-80 is needed to enhance its enzyme saccharification.

• Journal of Energy Engineering
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• v.20 no.3
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• pp.224-230
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• 2011

For developing high performance fuel cell, peripheral devices and key components have to be studied in priority. In this study, centrifugal pump was studied for heat recovery. For PEM fuel cell system, a four-impeller centrifugal pump was designed, tested and compared with result of commercial product (IWAKI). In addition, effects of number of impeller were analyzed by CFD. The experiment and analysis were progressed in the same conditions. The results showed the quantitative difference under 30% between the numerical and the experimental pressure difference and mass flow rate.

• Journal of Sensor Science and Technology
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• v.7 no.6
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• pp.409-417
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• 1998

Originally, the reference white of the NTSC system used to be CIE illuminant C of 6774K. However, that of color television receiver has been adjusted to 9300K as a result of consumer preference for a very bluish white for monochrome television. Recent studies have revealed that the preferred color temperature of display white should be 3000K or 4000K higher than that of surround illuminant. Therefore it is required to classify ambient lighting source. In this paper, a efficient method that can distinguish the ambient incandescent lamp from fluorescent lamp under television viewing condition is developed using only two color sensors, yellow and cyan. Experimental results show that the proposed method is very useful for the discrimination of ambient lighting source, fluorescent of 6000K and incandescent lamp of 3000K. The system was also tested for mixture of these light sources.

• Journal of Biomedical Engineering Research
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• v.24 no.1
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• pp.15-21
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• 2003

In this study, for a safetv assessment of light weight wheelchair occupant in frontal crash, we tested a dynamic sled impact test. we carried out total 6 times test and impact speed was 20g/48 km/h. By using Hybrid III 50%ile male dummy, head injury criteria(HIC), neck flexion moment, neck axial tension force, neck shear force. chest acceleration, head, wheelchair and knee excursion were measured, we evaluated light weight wheelchair occupant safety by motion criteria(MC) which proposed in SAE J2249 and combined injury criteria(CIC) which is a voluntary standard(GM-IARV) of General Motors Co.. when we assumed that the maximum injury value in frontal crash was 100%, the result of motion criteria(MC) of wheelchair occupant was 52%, occupant upper body injury index(CIC) was 60.1%.