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Significant Correlation between Salivary and Serum Ca 15-3 in Healthy Women and Breast Cancer Patients

  • Laidi, Fatna;Bouziane, Amal;Lakhdar, Amina;Khabouze, Samira;Amrani, Mariam;Rhrab, Brahim;Zaoui, Fatima
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4659-4662
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    • 2014
  • The tumor marker CA 15-3 is one of the most import reliable for metastatic breast cancer monitoring. While it is generally assessed in serum of patients, blood sampling is an invasive method compared to saliva sampling which is simple and could be an alternative to blood according to many studies. The aim of this investigation was to assess the relationship between serum and salivary concentrations of the protein CA 15-3 in patients with breast cancer and healthy asymptomatic volunteers. A case-control study was conducted with 60 women: 29 breast cancer patients from the Maternity Hospital Souissi Rabat (Morocco) and 31 healthy asymptomatic women. The CA 15-3 concentrations in saliva and serum samples were assessed using an enzyme immune assay (EIA kits) and comparison between cases and controls was made by the Mann-Whitney test. The correlation between serum and saliva CA 15-3 concentration was tested using Pearson correlation. The comparison result of CA15-3 concentration in saliva and serum level in cases and controls was not statistically significant (p>0.05). However, the correlation between salivary and serum CA 15-3 concentration was positive and statistically significant (r=0.27, p=0.03). In conclusion, the positive correlation between salivary and serum expression found in our study suggests that saliva could be an alternative to blood sampling to help breast cancer monitoring.

A Study on Standardization of UPS (Uninterruptible Power Supply) for Traffic Signal Controller (교통신호제어기용 무정전전원장치 용량기준 연구)

  • Ko, Kwang-Yong;Lee, Choul-Ki;Kim, Min-Sung;Heo, Nak-Won;Jeong, Jun-Ha
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.11 no.5
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    • pp.1-6
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    • 2012
  • Unlike the past, modern urban intersections have dramatic growth in size and utilizations. As a result, continual traffic signal control is essential. Hence the individual or regional electrical blackout may bring about uncontrollable traffic congestion. Late summer of 2011 a regional blackout brought about traffic nightmare not including time and revenue loss associated with this disaster. Due to this disaster our national police agency and other government agencies are in process of introducing an UPS (uninterruptible power supply) system into essential intersections. This study estimates the power consumption necessary to sustain at least 2 continuous hours for a standard four-legged intersection. Prototype was studied using these standards. The field experiment of prototype showed positive results and was able to meet standard guidelines set forth. Prototype tested was able to meet standards in medium to large capacity of traffic size.

Simple Algorithm for Large-scale Unbalanced Transportation Problem (대규모 불균형 수송문제의 간단한 해법)

  • Lee, Sang-Un
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.4
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    • pp.223-230
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    • 2015
  • As the Transportation Simplex Method of the general transportation problem are inapplicable to the large-scale unbalanced transportation problem, a commercialized linear programming package remains as the only viable means. There is, however, no method made available to verify the optimality of solutions attained by the package. This paper therefore proposes a simple heuristic algorithm to the large-scale unbalanced transportation problem. From a given problem of $31{\times}15$supply and demand areas, the proposed algorithm determines the number of demands areas for each supply area and executes on the latter in the ascending order of each of their corresponding demand areas. Next, given a single corresponding demand area, it supplies the full demand volume and else, it supplies first to an area of minimum associated costs and subsequently to the rest so as to meet the demand to the fullest extent. This initial optimal value is then optimized through an adjustment process whereby costs are minimized as much as possible. When tested on the $31{\times}15$cost matrix, the proposed algorithm has obtained an optimal result improved from the commercial linear programming package by 8.9%.

A Study on Distributed System Construction and Numerical Calculation Using Raspberry Pi

  • Ko, Young-ho;Heo, Gyu-Seong;Lee, Sang-Hyun
    • International journal of advanced smart convergence
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    • v.8 no.4
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    • pp.194-199
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    • 2019
  • As the performance of the system increases, more parallelized data is being processed than single processing of data. Today's cpu structure has been developed to leverage multicore, and hence data processing methods are being developed to enable parallel processing. In recent years desktop cpu has increased multicore, data is growing exponentially, and there is also a growing need for data processing as artificial intelligence develops. This neural network of artificial intelligence consists of a matrix, making it advantageous for parallel processing. This paper aims to speed up the processing of the system by using raspberrypi to implement the cluster building and parallel processing system against the backdrop of the foregoing discussion. Raspberrypi is a credit card-sized single computer made by the raspberrypi Foundation in England, developed for education in schools and developing countries. It is cheap and easy to get the information you need because many people use it. Distributed processing systems should be supported by programs that connected multiple computers in parallel and operate on a built-in system. RaspberryPi is connected to switchhub, each connected raspberrypi communicates using the internal network, and internally implements parallel processing using the Message Passing Interface (MPI). Parallel processing programs can be programmed in python and can also use C or Fortran. The system was tested for parallel processing as a result of multiplying the two-dimensional arrangement of 10000 size by 0.1. Tests have shown a reduction in computational time and that parallelism can be reduced to the maximum number of cores in the system. The systems in this paper are manufactured on a Linux-based single computer and are thought to require testing on systems in different environments.

Development and Application of Algorithm Teaching Materials Centered on Plays for Problem-solving Abilities of Elementary Students (초등학생의 문제해결력을 위한 놀이 중심 알고리즘 교재 개발 및 적용)

  • Baek, Seon-Ryeon;Song, Jeong-Beom;Park, Jung-Ho;Lee, Tae-Wuk
    • The Journal of Korean Association of Computer Education
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    • v.11 no.1
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    • pp.85-95
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    • 2008
  • The purpose of this study is to develop and apply the algorithm teaching materials centered on plays(ATMCP) to improve problem-solving abilities of elementary students. For this goal, the ATMCP were reviewed by the expert group and tested them out on 71 fifth-grade elementary students in Daegu, Korea during the 6 weeks. We divided students into two groups: one is the group of the ATMCP and the other is the group of conventional algorithm teaching materials(ATM). And we analyzed the change of the problem-solving ability of each group between before and after using two types of teaching materials with the Mixed ANOVA. The result showed that there was a significant difference in students' problem-solving abilities between before and after using them and the group of the ATMCP was greater improvement than the group of the conventional ATM in a problem-solving ability.

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The Effect of Storycrafting Program on Mathematical Creativity and Communication (스토리크래프팅 프로그램이 수학적 창의성 및 의사소통능력에 미치는 영향)

  • Lee, Hyewon;Chang, Hyewon
    • Journal of Elementary Mathematics Education in Korea
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    • v.20 no.4
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    • pp.677-694
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    • 2016
  • Storycrafting is a creative educational technique in Finland. Since 2011, storytelling approach of mathematics textbooks in South Korea can be regarded as opportunities for interesting learning of mathematics as well as its improper application to mathematics lessons. We need to revise and improve the storytelling method. The purpose of this study is to make a storycrafting program that encourages students to make mathematical stories for themselves and to analyze the effect of the storycrafting program on mathematical creativity and communication. To do so, we developed a storycrafting program of mathematics for sixth graders, which is composed of 33 lessons. And we applied them to one sixth class as experimental group. Through pre-test and post-test, their mathematical creativity and communication were tested. Based on the result of t-test, we can verify the statistical meaningful effect of the storycrafting program. This study contains some conclusions and suggestions.

Do Inner Planets Modulate the Solar Wind Velocity at 1 AU from the Sun?

  • Kim, Jung-Hee;Chang, Heon-Young
    • Journal of Astronomy and Space Sciences
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    • v.31 no.1
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    • pp.1-6
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    • 2014
  • Quite recently, it has been suggested that the interaction of the solar wind with Mercury results in the variation in the solar wind velocity in the Earth's neighborhood during inferior conjunctions with Mercury. This suggestion has important implications both on the plasma physics of the interplanetary space and on the space weather forecast. In this study we have attempted to answer a question of whether the claim is properly tested. We confirm that there are indeed ups and downs in the profile of the solar wind velocity measured at the distance of 1 AU from the Sun. However, the characteristic attribute of the variation in the solar wind velocity during the inferior conjunctions with Mercury is found to be insensitive to the phase of the solar cycles, contrary to an earlier suggestion. We have found that the cases of the superior conjunctions with Mercury and of even randomly chosen data sets rather result in similar features. Cases of Venus are also examined, where it is found that the ups and downs with a period of ~ 10 to 15 days can be also seen. We conclude, therefore, that those variations in the solar wind velocity turn out to be a part of random fluctuations and have nothing to do with the relative position of inner planets. At least, one should conclude that the solar wind velocity is not a proper observable modulated by inner planets at the distance of 1 AU from the Sun in the Earth's neighborhood during inferior conjunctions.

Real-time hybrid substructuring of a base isolated building considering robust stability and performance analysis

  • Avci, Muammer;Botelho, Rui M.;Christenson, Richard
    • Smart Structures and Systems
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    • v.25 no.2
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    • pp.155-167
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    • 2020
  • This paper demonstrates a real-time hybrid substructuring (RTHS) shake table test to evaluate the seismic performance of a base isolated building. Since RTHS involves a feedback loop in the test implementation, the frequency dependent magnitude and inherent time delay of the actuator dynamics can introduce inaccuracy and instability. The paper presents a robust stability and performance analysis method for the RTHS test. The robust stability method involves casting the actuator dynamics as a multiplicative uncertainty and applying the small gain theorem to derive the sufficient conditions for robust stability and performance. The attractive feature of this robust stability and performance analysis method is that it accommodates linearized modeled or measured frequency response functions for both the physical substructure and actuator dynamics. Significant experimental research has been conducted on base isolators and dampers toward developing high fidelity numerical models. Shake table testing, where the building superstructure is tested while the isolation layer is numerically modeled, can allow for a range of isolation strategies to be examined for a single shake table experiment. Further, recent concerns in base isolation for long period, long duration earthquakes necessitate adding damping at the isolation layer, which can allow higher frequency energy to be transmitted into the superstructure and can result in damage to structural and nonstructural components that can be difficult to numerically model and accurately predict. As such, physical testing of the superstructure while numerically modeling the isolation layer may be desired. The RTHS approach has been previously proposed for base isolated buildings, however, to date it has not been conducted on a base isolated structure isolated at the ground level and where the isolation layer itself is numerically simulated. This configuration provides multiple challenges in the RTHS stability associated with higher physical substructure frequencies and a low numerical to physical mass ratio. This paper demonstrates a base isolated RTHS test and the robust stability and performance analysis necessary to ensure the stability and accuracy. The tests consist of a scaled idealized 4-story superstructure building model placed directly onto a shake table and the isolation layer simulated in MATLAB/Simulink using a dSpace real-time controller.

Proposed image encryption method using PingPong256

  • Kim, Ki-Hwan;Lee, Hoon Jae;Lee, Young Sil
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.1
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    • pp.71-77
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    • 2020
  • In this paper, we propose a method in which PingPong256 combines LFSR and variable clock to generate an irregular PRNG and use it for image encryption. PingPong256 is guaranteed an extended period based on the two LFSRs, and the variable clock is a structure that outputs the result of operating a predetermined clock in one operation by referring to the state of the different LFSR. A variable clock is characterized by the difficulty of predicting the output at any time because the choice increases with time. PingPong256 combines the advantages of LFSR and variable clock, the convenience of hardware and software implementation, and the benefits of sensitivity and irregular periods. Also, the statistical safety was verified using the NIST SP800-22, the safety of the proposed method, and the sensitivity of the image change was tested using NPCR and UACI.

Bitcoin Distribution in the Age of Digital Transformation: Dual-path Approach

  • Lee, Won-Jun;Hong, Seong-Tae;Min, Taeki
    • Journal of Distribution Science
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    • v.16 no.12
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    • pp.47-56
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    • 2018
  • Purpose - The potential use of cryptocurrencies in a retail environment proposes a rapid shift from the traditional financial system. Nakamoto(2008) defines Bitcoin as an open source alt-coin based on the blockchain technology. Luther(2016) insists that the new technology will be widely adopted for the digital payment processes. However, the use of Bitcoin is in the real world is still sparse. Despite the growing attention and purported benefits, it is doubtful whether the Bitcoin will be eagerly accepted by ordinary consumers in the mainstream market. To answer this question, this paper develops a causal model that has a dual path to explain the motivation to adopt Bitcoin. According to Glaser, Zimmermann, Haferkorn, Weber, and Siering(2014), Bitcoin is both an asset and a currency at the same time. In summary, the attitude towards Bitcoin may vary depending on whether the fin-tech product is viewed as an asset or as a currency. Based on the arguments, we propose that asset attitude and currency attitude will give influence to consumers' intention to adopt Bitcoin. Research design, data, and methodology - Quantitative data collection is conducted from a Bitcoin SIG(special interest group) working in an internet community. As a result, 192 respondents who know Bitcoin completed the survey. To analyze the causal relations in the research model, PLS-SEM(partial least squares structural equation modeling) method is used. Also, reliability and validity of measures are tested by performing Cronbach's alpha test, Fornell-Larcker test and confirmatory factor test. Results - Our test results show that every hypothesis is supported except the influence of perceived ease of use. In addition, we find that the relationships between constructs are different between the high innovative group and low innovative group. Conclusions - We provide evidence that asset attitude and currency attitude are key antecedents of Bitcoin adoption.