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Effects of Cinnamomi Cortex on Hypercholesterolemia Induced by Estradiol Valerate in Rats (육계(肉桂)가 Estradiol valerate에 의하여 유발된 고콜레스테롤 혈증에 미치는 영향)

  • Choi, Eu-Gene;Kim, Hyung-Woo;Chung, Hee-Jin;Joung, Young-Min;Shin, Dong-Sung;Cho, Su-In
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.2
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    • pp.264-269
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    • 2011
  • This study was designed to investigate the effects of Cinnamomi Cortex extract (CC) on hypercholesterolemia induced by Estradiol valerate (EV) in female rats. We investigated the effects of CC on Changes in body weights for 5 weeks. In addition, we examined the effects on fasting blood glucose (FBS) and tested oral glucose tolerance test after oral administration of CC for 5 weeks. We also investigated the effects on levels of total cholesterol, HDL-cholesterol and LDL-cholesterol in serum. Treatment with CC restored weight gain rates suppressed by EV significantly. CC did not affect serum glucose level and glucose tolerance. Levels of total cholesterol and triglyceride were lowered by administration of CC compared to EV treated control respectively. These result suggest that CC can lower serum cholesterol level then prevent weight loss induced by EV. We also suggest the possibility as anti-hyperlipidemic agent of CC.

Development of Integrated CAE System for Mechanical Shock Proof Design of TFT-LCD Modules (TFT-LCD 모듈의 내충격성 향상을 위한 통합 CAE 시스템의 개발)

  • 서형원;문성인;구자춘;최재붕;김영진;최성식;이정권
    • Journal of the Korean Society for Precision Engineering
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    • v.21 no.9
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    • pp.135-141
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    • 2004
  • Anti-shock performance is one of the most important design specifications of TFT-LCD modules. Since they are adopted fur major display units of many mobile applications such as lap-top PCs, cellular phones, and palm pilots, they are able to accommodate and endure high level transient mechanical energy inputs. For the reasons, not only the LCD unit manufacturers but their customers like PC makers perform a series of strict impact/drop test on the units. Currently, designers are mostly relying on their own trial-error based experience for the anti-shock design. Thus those designs depending on only experience may result in disqualification from the drop/impact test during final product evaluation. Those shock failures of any new designs are prohibitive for both LCD and PC manufacturers. In order to avoid this problem, many designers are focusing on the development of computer-aided design tools that is directly connected to shock simulation capabilities and then shock-proof design cycle time could be significantly reduced. Development of an integrated CAE system for the shock-proof design is presented in this article. At every stages of the development of present work, practical industrial applicability and mass production feasibility are seriously considered and tested so that the system is to be used in the LCD design engineering field.

Antioxidative and Antimicrobial Effects of Nut Species (Nut류의 항산화 및 항균효과)

  • Lee, Hye-Won;Choi, Moo-Young;Cha, Bae-Cheon
    • Korean Journal of Pharmacognosy
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    • v.29 no.1
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    • pp.28-34
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    • 1998
  • It has been known that diseases related with aging or cancer result, at least in part, from free radicals, and antioxidants may reduce or prevent the abnormalities associated with free radical formation via its scavenging action. Thus, this study was carried out to investigate the antioxidative and antimicrobial activities of nut species for the purpose of developing antioxidant from natural products. Antioxidant activities of four kinds of nuts such as chestnut, groundnut, walnut and acorn were examined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. The extracts from chestnut hull and acorn barnyard millet showed strong antioxidative activities among 10 samples tested. Because of their highest antioxidative activity among 10 samples, radical scavenging effects of 4 different extract compartments (Hexane, EtOAc, BuOH and $H_2O$ extracts) from chestnut hull and acorn barnyard millet, were further examined by DPPH method. EtOAc and BuOH extracts exhibited antioxidative activities similar to those of natural, tocopherol or synthetic antioxidants, BHA. These findings demonstrates that major fraction of the antioxidative activity of chestnut hull or acorn barnyard millet was the EtOAc and BuOH extract compartments. However, antimicrobial activities against food-related bacteria and yeasts was relatively weak.

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Evaluation of Cytotoxic Potential of Indonesian Medicinal Plants in Cultured Human Cancer Cells

  • Park, Go-Woo-Ni;Lee, Eun-Jin;Min, Hye-Young;Choi, Hye-Young;Han, Ah-Reum;Lee, Sang-Kook;Seo, Eun-Kyoung
    • Natural Product Sciences
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    • v.8 no.4
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    • pp.165-169
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    • 2002
  • One-hundred and twenty plant extracts were prepared from 29 Indonesian plants and were primarily tested in vitro cytotoxicity in cultured human lung (A549), colon (Col2), and stomach (SNU-638) cancer cells. As a result, the 23 extracts were found to be active in the criteria of $ED_{50}$<$20\;{\mu}g/ml$. Remarkable cytotoxicity was observed for chloroform and n-butanol extracts of Calotropis gigantea, with $ED_{50}$ values ranging from 0.25 to $0.46\;{\mu}g/ml$. Five extracts derived from Eclipta alba and Excoecaria cochinchinensis displayed potent cell-line selective cytotoxicity, while the rest of 15 extracts showed modest cytotoxic activity against all of three cancer cells. In addition, the cytotoxic potential of subfractions of Zingiber cassumunar against a panel of human cancer cell lines is presented.

A Study on the Development of Enjoyment Indicators of Public Libraries (공공도서관 향유지표 개발에 관한 연구)

  • Cha, Mi-Kyeong;Pyo, Soon-Hee
    • Journal of the Korean Society for Library and Information Science
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    • v.42 no.4
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    • pp.329-354
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    • 2008
  • The purpose of this study is to develop the indicators for measuring enjoyment of public libraries by the community. The term, enjoyment is defined as the community members' use and appreciation. Four types of enjoyment indicators are constructed through literature review: basic(environment), state(use), result(outcome), and essential(to enhance enjoyment). The prepared enjoyment indicators are evaluated and selected by focus groups interviews of professionals(researchers, librarians and policy makers). Those selected indicators are tested and revised through a internet survey of 508 Kyungi residents. Based on the analysis of the results this study suggests a total of 46 enjoyment indicators.

High-Temperature Rupture of 5083-Al Alloy under Multiaxial Stress States

  • Kim Ho-Kyung;Chun Duk-Kyu;Kim Sung- Hoon
    • Journal of Mechanical Science and Technology
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    • v.19 no.7
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    • pp.1432-1440
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    • 2005
  • High-temperature rupture behavior of 5083-Al alloy was tested for failure at 548K under multiaxial stress conditions: uniaxial tension using smooth bar specimens, biaxial shearing using double shear bar specimens, and triaxial tension using notched bar specimens. Rupture times were compared for uniaxial, biaxial, and triaxial stress conditions with respect to the maximum principal stress, the von Mises effective stress, and the principal facet stress. The results indicate that the von Mises effective and principal facet stresses give good correlation for the material investigated, and these parameters can predict creep life data under the multiaxial stress states with the rupture data obtained from specimens under the uniaxial stress. The results suggest that the creep rupture of this alloy under the testing condition is controlled by cavitation coupled with highly localized deformation process, such as grain boundary sliding. It is also conceivable that strain softening controls the highly localized deformation modes which result in cavitation damage in controlling rupture time of this alloy.

Efficiency Assessment of Turbine for Tidal Current Power Plant by In-Field Experimental Test (현장계측에 의한 조류 발전용 수차의 효율 평가)

  • Han, Sang-Hun;Lee, Kwang-Soo;Yum, Ki-Dai;Park, Woo-Sun;Park, Jin-Soon;Yi, Jin-Hak
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.06a
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    • pp.517-520
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    • 2006
  • The Korean peninsula has a number of coastal sites where the rhythmic rising and lowering of water surface due to tides results in strong tidal current. The kinetic energy of these currents can be efficiently exploited by use of tidal current turbines. The pilot tidal current power plant is to be constructed at the Uldolmok narrow channel between J info and Haenam, Our ins next Year, and extensive coastal engineer ing research works have been carried out. This paper describes and analyzes some observation results of field test about the efficiency of Helical turbine for tidal current power plant. The efficiency of turbine, which is diameter 2.2m and height 2.5m, is evaluated meximum RPM, torque, and current velocity. The tested turbines had the maximum efficiencies of the bounds of 25 to 35% in the current velocity range between 1.4 and 2.6 m/s. This result shows that the pilot tidal current power plant needs three helical turbines with diameter 3.0m and height 3.6m to produce electric power 500kW.

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A Study of Measurement of In-plane Displacement by CW Laser Speckle Photography and Image Processing (연속파 레이저 스페클 사진법(寫眞法)과 화상처리(畵像處理)에 의한 면내섭위(面內燮位) 측정(測定)에 관한 연구(硏究))

  • Kim, K.S.;Na, G.D.;Kim, T.H.;Chung, N.K.;Kim, C.W.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.10 no.1
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    • pp.47-55
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    • 1990
  • This paper presents experimental results which explore the capability of a CW laser speckle photography for tile measurement of in-plane displacement at high temperature. The serious restrictions on the application of the method seem to be the ambient air turbulence and the change of surface texture caused by the oxidation, as they tend to decorrelate the double exposured speckle patterns. In order to assess only the effect of air turbulence, a ceramics-coated stainless steel plate is heated in air and Ar-laser specklegrams are made with combination of temperature and lateral translation displacement. The slight reduction in visibility of Young's fringes is observed at $1000^{\circ}C$. The analyses of Young's fringes are carried out by a image processing system using a TV-camera and computers, and the result agrees well with the micrometer reading. Futhermore, uncoated stainless steel and Hastelloy X plates are tested and the effect of oxidation is also evaluated. The experimental results demonstrate that a CW laser speckle photography is applicable at temperatures up to $1000^{\circ}C$.

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Properties Evaluation on Aluminum for Die-casting(ADC 12) to Packing Case of Composite Sensor (복합센서 케이스용 알루미늄 다이캐스팅(ADC 12) 합금의 특성평가)

  • Son, Jae-Hwan;Oh, Sang-Kyun;Kim, Dong-Bae;Han, Chang-Woo
    • Journal of the Korean Society of Industry Convergence
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    • v.9 no.2
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    • pp.141-145
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    • 2006
  • In case of sense case manufactured by method of outage capacity, sensitivity is declined by outside effect and method of the photo electricity has a problem in transmission. therefore, packing case of composite sense should be developed to improve such a problem about influence of outside environment and its property evaluation has been performed. Mechanical property and result of analysis & test evaluation of Mat'l on aluminum die-casting(ADC 12type) Mat'l developed are as following. Tensile test piece, No. 4 of KS B 0801, has been applied to mechanical property test of Mat'l and It has been tested by method of metal mat'l tensile test(KS B 0802 : 2003). It can be found that physical property to KS(Korea Standard) is excellent. and homogeneous mechanical property appears. Test of Mat'l analysis has been performed by using OE Spectrometer, according to ASTM E 1251 : 1994 regulation. Consequently, good and homogeneous component contents classified by element to standard, except for Fe, have been obtained with coordination of Fe content as below 1.3% from composition standard of Aluminum Die-casting.

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Fracture Behavior of Fiber Reinforced Composites under tensile and Bending Loadings (섬유강화 복합재료의 인장 및 굽힘에 의한 파괴)

  • Nam, Gi-U;Mun, Chang-Gwon
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.30 no.1
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    • pp.45-52
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    • 1994
  • The study was conducted to evaluate reliability of the longitudinal tensile properties of unidirectional carbon fiber reinforced composites. Two kinds of carbon fiber reinforced composites laminates were tested in order to examine the factors of variability and have the information concerning reliability improvement. Temperature dependence of the strength and its variability were investigated by means of testing at two kinds of temperatures. Statistical distributions of the respective mechanical properties were obtained from the tensile tests. As a result, strength of composites was directly proportional to the ultimate strain and was not proportional to the elastic modulus. The fracture behavior in bending of notched plate was studied for a composite material. The uniform bending tests of notched plates have been carried out for a wide range of notch radii. The experiment shows that the nominal stress at failure decreased with decreasing notch radius and it approaches a constant value when the notch radius is less than about 0.3mm. The critical maximum stress is governed by notch root radius alone in the case of a constant thickness of specimen.

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