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Inhibitory Effects of Fractions from Glycine soja Siebold et Zucc. on Melanogenesis in B16F10 Melanoma Cells (B16F10 멜라닌 세포에서 약콩(Glycine soja Siebold et Zucc.) 분획 추출물의 멜라닌 생성 저해 효과)

  • Kim, Bo Ae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.43 no.3
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    • pp.231-237
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    • 2017
  • This study was performed to cytotoxicity, tyrosinase inhibition activity, intracellular melanin contents to verify the whitening effect of fraction from Glycine soja Siebold et Zucc. (G. soja). Using western blotting, tyrosinase expression in B16F10 melanoma cells and expression levels of tyrosinase related protein-1 (TRP-1) and protein-2 (TRP-2) were examined. As a result, all of the fractions showed a high cell viability over 82% at the concentrations of 0.125, 0.25, 0.5, 2.0 mg/mL. When the whitening effects of fractions from G. soja were tested using B16F10 melanoma cells treated with the ${\alpha}$-melanocyte stimulating hormone (${\alpha}-MSH$), the EtOAc fractions inhibited tyrosinase and melanogenesis effectively. The result of protein expression measurement using western blot showed that TRP-1, TRP-2 and tyrosinase protein expression in B16F10 melanoma cells treated with extracts decreased. Therefore, it is concluded that the fractions from G. soja have whitening effect by inhibiting protein related melanogenesis.

The impact of collaboration process and capabilities on innovation performance in convergence environment (융복합 환경에서 기업 내부 협업프로세스와 역량이 혁신성과에 미치는 영향)

  • Kim, Hoon;Park, Kyung-Hye
    • Journal of Digital Convergence
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    • v.13 no.5
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    • pp.151-158
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    • 2015
  • The purpose of this study to understand collaborative process and the capabilities of the firm impact on innovation performance in convergence environment. To achieve the purpose, research model was empirically tested with a survey from 162 employees from 4 Korea manufacturing companies and 1 USA company. The data obtained from the survey were analyzed using Partial Least Squares (PLS). As a result, collaboration process, learning capability and operation capability have significant and positive impact on innovation performance. It is a meaningful result that the collaboration process improve the innovation performance of firms through the operation capability and the learning capability.

A Study on the Development of Collaborative Learning Model and Behavioral Elements in e-Learning Environment (e-Learning 환경에서의 협력학습을 위한 학습모형 및 학습행위요소 개발)

  • Lee, Insook;Leem, Junghoon;Sung, Eunmo;Jin, Sunghee
    • The Journal of Korean Association of Computer Education
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    • v.9 no.2
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    • pp.27-36
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    • 2006
  • This study intends to present essential models for collaborative learning in e-learning environment as well as to analyze learning behavior elements appearing in collaborative learning activities. In order to achieve goal of the study, the researchers analyzed existing cooperative learning models for face-to-face classroom, collaborative activity models based on instructional theory, and the structures and activities elements of learning community and collaborative activity models focusing on e-learning environment. As a result of the study, the researchers produced a generalizable collaborative learning model for e-learning which include general collaborative learning model, and further analyzed specific learning behaviors performed by learners while they proceed in this model based learning processes. The adequacy of this model and reliability of learning behavior elements were tested through experts' review meetings. The research result, suggesting generalizable collaborative learning model as well as learning behaviors elements which might occur within e-learning based collaborative learning, might work as a foundational model for software infrastructure and e-learning solution business. Moreover, its value might be maximized if its being used for enhancing learning content interoperability and reuse as well as for establishing international standardization for collaborative technology.

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Electromagnetic Environment Analysis of Goheung Aviation Center (고흥항공센터의 전기장 환경 분석)

  • Jang, Kyung-Duk;Kim, Tae-Youn;Jang, Jae-Woong;Min, Byong-Hee;Cho, In-Kyoung;Moon, Guee-Won
    • Aerospace Engineering and Technology
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    • v.12 no.1
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    • pp.46-53
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    • 2013
  • In this study, the analysis of electromagnetic environment of goheung aviation center was performed. If the test object has restrictions to be tested in indoor test facility, open area test site can be used to perform EMC test. Open area test site shall have no obstacles that can generate or reflect the electric field so as to prevent the measurement result from being influenced by unnecessary field. Goheung aviation center is surrounded by fields, and has no buildings that can reflect electric field, so the center can be a good candidate for open area test site. Ambient noise at Goheung aviation center was measured, and the result show that the center has good electromagnetic environment to perform EMC test for large volume object.

Spray characteristics and performance of pressure swirl simplex injector for heavy duty industrial gas turbines (대형가스터빈용 단일 압력 선회식 연료분사기의 분무 특성 및 성능 평가)

  • Seok, Jungmin;Jeong, Hanjin;Choi, Inchan;Kim, Jaiho;Lee, Sanghoon
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2017.05a
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    • pp.892-895
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    • 2017
  • As a component development of heavy duty industrial gas turbine combustor development program, pressure swirl simplex injector was designed and tested to figure out spray characteristics and performance. Injector flow rate as a function of pressure drop was measured and compared to the design target. Also spray shape was analyzed qualitatively and spray cone angle was measured from spray visualization image using shadowgraph. The flow test result showed that the injector was designed and manufactured correctly according to the design target and spray cone angle was measured from shadowgraph result. As a next step, PDA (Phase Doppler Anemometry) measurement is planned to figure out more specific spray performance and characterization.

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A Development of Method for Surface and Subsurface Runoff Analysis in Urban Composite Watershed (II) - Analysis and Application - (대도시 복합유역의 지표 및 지표하 유출해석기법 개발 (II) - 분석 및 적용 -)

  • Kwak, Chang-Jae;Lee, Jae-Joon
    • Journal of Korea Water Resources Association
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    • v.45 no.1
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    • pp.53-64
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    • 2012
  • In this study (II), the module developed in the previous study (I) has been tested on application and numerical stability. The runoff module was compared the result of analysis with two different models (FFC2Q and $Vflo^{TM}$) considering characteristic of infiltration. To examine the application and stability of developed module, runoff aspect was simulated under the variety case of rainfall intensity, effective soil depth, elapsed time. The development module was presented typical type of infiltration process looking physically, the different of saturation point on soil type, and characteristic of soil type. Also, the module was reflected in the runoff feature about rainfall intensity and time distribution. Finally, this paper drew a conclusion that result of rainfall-runoff analysis as compared with difference models (FFC2Q and $Vflo^{TM}$) has a high accuracy.

Implementation of Game Interface using Human Head Motion Recognition (사람의 머리 모션 인식을 이용한 게임 인터페이스 구현)

  • Lee, Samual;Lee, Chang Woo
    • Journal of Korea Society of Industrial Information Systems
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    • v.19 no.5
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    • pp.9-14
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    • 2014
  • Recently, various contents using human motion are developed in computer vision and game industries. If we try to apply human motion to application programs and contents, users can experience a sense of immersion getting into it so that the users feel a high level of satisfaction from the contents. In this research, we analyze human head motion using images captured from an webcam and then we apply the result of motion recognition to a game without special devices as an interface. The proposed method, first, segments human head region using an image composed of MHI(Motion History Image) and the result of skin color detection, and then we calculate the direction and distance by the MHI sequence. In experiments, the proposed method for human head motion recognition was tested for controlling a game player. From the experimental results we proved that the proposed method can make a gammer feel more immersed into the game. Furthermore, we expect the proposed method can be an interface of a serious game for medical or rehabilitation purposes.

The Study on the Strength Properties of High Volume Fly-Ash Concrete (플라이애시를 다량 사용한 콘크리트의 강도특성에 관한 연구)

  • Paik, Min-Su;Lee, Young-Do;Jung, Sang-Jin
    • Journal of the Korea Institute of Building Construction
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    • v.2 no.4
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    • pp.169-176
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    • 2002
  • To study of binder and fine aggregate a lot of replacement fly-ash concrete, initial characteristics, standard environment of curing temperature $20^{\circ}C$, hot-weather environment, cold weather environment of curing temperature $5^{\circ}C$. Flash concrete tested slump, air contest, setting and Hardening concrete valuated setting period of form, day of age 3, 7, 28 compression strength in sealing curing. Underwater curing specimen compression strength of age 3. 7, 28day used strength change accordingly fly-ash concrete curing temperature. Purpose of study is consultation materials in field that variety of fly-ash replacement concrete mix proportion comparison and valuation. (1) Setting test result, fly-ash ratio of replacement higher delay totting time. Same volume of fly-ash ratio of replacement is lower fly-ash ratio of replacement fine aggregate delay setting time. Setting test in curing temperature $35^{\circ}C$ over twice fast setting in curing temperature $20^{\circ}C$ and all specimen setting delay in curing temperature $5^{\circ}C$. F40 specimen end of setting about 30 time. (2) Experiment result age 28day compression strength more fisher plan concrete then standard environment in curing temperature $20^{\circ}C$, cold weather environment in curing temperature $5^{\circ}C$, most strength F43 is hot-weather environment in curing temperature $35^{\circ}C$ replacement binder 25%, fine aggregate 15%. (3) Hot-weather environment replacement a mount of fly-ash is a same of plan concrete setting period of form. Age 28day compression strength replacement a mount of fly-ash more hot-weather concrete then plan concrete.

Development of EM Wave Absorber for Countermeasure against EM Wave Environment of 2.4 GHz Wireless LAN (2.4 GHz 무선LAN 전자파 환경대책용 전파흡수체 개발)

  • Yoon, Sang-Gil;Kim, Dae-Hun;Park, Soo-Hoon;Kim, Dong-Il
    • Journal of Navigation and Port Research
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    • v.33 no.3
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    • pp.193-197
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    • 2009
  • In this paper, the EM wave absorber was designed and fabricated for improvement of Wireless LAN environment at 2.4 GHz. We fabricated several samples in different composition ratios of Sendust and CPE(Chlorinated Polyethylene). Absorption abilities were simulated in accordance with different thicknesses of the prepared absorbers and changed complex relative permittivity and permeability due to composition ratio. The mixing ratio of Sendust and CPE was searched as 80: 20 wt.% by experiments and simulation Then the EM wave absorber was fabricated and tested using the simulated data. As a result, the EM wave absorber was fabricated based on simulated data. Simulated and measured results agreed well. As a result, the developed EM wave absorber with thickness of 3.25 mm has absorption ability of 19 dB at 2.4 GHz.

Korea High Speed Train Design - focused on aerodynamic optimal form design development (한국형 고속전철 디자인 -공기역학적 최적형상 디자인개발을 중심으로-)

  • 이병종
    • Archives of design research
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    • v.17 no.3
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    • pp.123-132
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    • 2004
  • This paper shows a study on the "Korean High Speed Train Design" method, its design process and the result in the form of aerodynamic optimal exterior design development of a prototype test train(HSR 350${\times}$). It was developed from 1996 until 2002, six years long in R '||'&'||' D project titled "Development of High Speed Railway Technology" The end result of the project is a prototype test train, which has two power cars, two motorized trailers and three trailers, had been tested successfully in the year 2003 to the highest speed limit 380km/h on high speed line. The improved conceptual design work of a new commercial train and next generation's train is also performed for future needs.uture needs.

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