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Research for the antiinflamation and antioxidation effect on the Lycoris squamigera Maxim (소염 및 항산화제 개발을 위한 상사화의 효능 연구)

  • Kim, Bo-Mi;Yoo, Myung-Ja;Song, Mi-Seon;Kwon, Tae-Oh;Lee, Young-Hang;Chai, Kyu-Yun
    • Herbal Formula Science
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    • v.19 no.2
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    • pp.109-118
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    • 2011
  • Objectives : The Lycoris squamigera Maxim has been used traditionally for treatment of various diseases. However, the studies on the effect of Lycoris squamigera Maxim have not been carried out. In the present study, extract of Lycoris squamigera Maxim were tested for their anti-inflammatory and anti-oxidation effect. Methods : The anti-inflammatory effect of the various solvent extract was studied in lipopolysaccharide (lps)-treated mouse macrophage cells. RAW 264.7 cells were pre-incubated with Lycoris squamigera Maxim extracts for 4h and treated with $1\;{\mu}g/m{\ell}$ lps for 18h, and then the anti-inflammatory effects of extracts were determined. The anti-oxidation effect of extracts measured by DPPH method, reductive potential test, total phenolics test. Results : Extracted root's ethyl acetate layer showed a significant decrease in nitric oxide. And that layer (root's ethyl acetate extract) was showed decrease in TNF-${\alpha}$ concentration dependently. Separated from Root's ethyl acetate extract was fraction 1 has $0.1{\sim}5\;{\mu}M$ range, fraction 2 has $0.1{\sim}10\;{\mu}M$ range did not showed cytotoxicity. Anti-oxidation result as DPPH test showed the best was root ethyl acetate extract. Redusing power was made a comparison between fractions and standard. They were showed similar value. Fraction's total phenol containing result was better then standard. Conclusions : These results suggest that these extracts can be used as anti-inflammatory, anti-axidation materials.

Study about Oriental Medical Diagnosis and Approach Related to Weighting According to Differentiation of Chronic Tension-type Headaches (만성 긴장성 두통의 한의학적 진단 및 변증의 가중치에 대한 접근방법 연구)

  • Lee, Ki-Su;Kim, Min-Jung;Park, Mi-Ra;Lee, Sang-Bong;Hong, Kwon-Eui
    • The Journal of Korean Medicine
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    • v.31 no.5
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    • pp.41-59
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    • 2010
  • Objective: Headache is one of the most common symptoms in primary medical care. The purpose of this study was to support medical treatment by consideration of a new CTTH (chronic tension-type headache) oriental medical diagnosis index. Methods: An Oriental medical diagnosis questionnaire was administered to a CTTH group, migraine group and normal group. The result was classified by using LDA, CART, factor diagnosis and tested in comparison with the original diagnosis. Also, weighting method based on expert opinions was done. Results: 1. The result analyzed by using LDA has an accuracy of 93.9% in comparison with the original diagnosis. 2. High accuracy showed when the test was performed with about 35 significant questions and four questions selected based on SPSS Wilks' lambda. 3. There was accuracy of 90.9% when differentiation was performed by using CART compared with original diagnosis. 4. 10 factors has a high initial value after factor analysis, consisting of questions to the similar differentiation. 5. Diagnosis formula of headache was made by using weighting method based on expert opinions. Conclusion: Oriental medical diagnosis questionnaires make it possible to classify headaches significantly. The study about weighting method of CTTH can make it possible to classify symptoms more accurately.

Structural analysis of a thick composite rotor hub system by using equivalent properties (등가 물성을 이용한 두꺼운 복합재 로터 허브 시스템의 구조 해석)

  • ;Yanti Rachmadini
    • Composites Research
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    • v.16 no.5
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    • pp.7-14
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    • 2003
  • Modeling of thick composite structures for finite element analysis is relatively complicated. 2-D plane elements may cause inaccurate result since the plane stress condition cannot be applicable in these structures. Therefore a 3-D modeling should be used. However, the difficulty to model all the layers with different material properties and ply orientation arise in this case. In this paper, an equivalent modeling is proposed and numerically tested for analysis of thick composite structures. By grouping layers with same material and ply orientation, number of elements through the thickness is remarkably reduced and still the result is close enough to the one from a detail finite element model. MSC/NASTRAN and PATRAN are used for the analysis. The proposed modeling technique has been applied for analysis of composite rotor hub system designed by Korea Aerospace Research Institute(KARI). Using the proposed equivalent modeling technique, we could conduct stress analysis for the hub system and check the safety factor of each part.

Consideration on Ease of Several Bodice Patterns (각종 부인복 원형의 여유감에 대한 고찰)

  • Geong Hyee Lag
    • Journal of the Korean Society of Clothing and Textiles
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    • v.14 no.4 s.36
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    • pp.274-280
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    • 1990
  • This paper is intended to grasp the characteristics of many bodices patterns which have been shown so far. The way is by selecting four characteristic kinds of patterns, making blouses offer the patterns and measuring ease. In measuring the degree of ease, $Scheff\`{e}'s$ paired comparison is made use of. In analysis, variation ratio has come out of analysis of variance, and significance is tested by producing estimated values between patterns. The Result is summed up as follows. 1. After wearing blouses made ofter different basic patterns and measuring ease, the analysis of variance is made about the sensory value of ease. The result is as follows. 1) In the ease of different patterns, all the areas are significant at the level of $1\%$ , regard- less of movements. 2) Under the influence of movements, the back area of arm hole is significant at the level of $5\%$ in narrow movements, and the front and the back area of arm hole are each significant at the level of $1\%$ in wide movements. 3) In the interaction of patterns and movements, bust and the under area of arm hole are each significant at the level of $1\%$ in narrow movements, and bust is significant at the level of $1\%$ in wide movements. 2. When comparing estimated values between patterns, the value of c is the largest and in the order of b,4, a. And in the other movements, the order changes into c,d, b and a. Thus the ease of blouses is different according to patterns. The reason for this is that the amount of ease of bust, the amount and location of darts, and sleeve cap height have complicate influences on the ease of blouses. Both sleeve cap height and the depth of arm hole have influences on the ease of sleeve. Consequently, in making clothes, it would be better to select and use proper patterns which go with the purposes and desings of clothes rather than to apply one pattern to various clothes.

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Analysis on User's Willingness to Pay for Value Measurement of Planned Infrastructure in the Settlement Zone - Around the District Unit Plan of the Settlement Zone in Cheongju-city - (취락지구의 계획기반시설 가치 측정을 위한 사용자 지불의사 분석 - 청주시 자연취락지구 지구단위계획을 중심으로 -)

  • Yun, Ki-Bum;Hong, Eui-Dong;Hawang, Hee-Yun
    • Journal of Korean Society of Rural Planning
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    • v.19 no.4
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    • pp.1-15
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    • 2013
  • The purpose of this study is to quantitatively analyze the corresponding residents' benefit to get in the future from the district unit plan of the settlement zone by Cheongju local government. The target districts were selected as Gumdeong-gol district, Juseong district, and Shinmok-gol district, and Hyeonam district which had recently set their district unit plans. Specific targets to be analyzed were some infrastructure including roads, parking lots, parks and others. Using the analysis methods of the Logit model and non-parametric test approach, this study estimated to the average amounts to be willingly paid(WTP) by the residents in targeting settlement zones and tested the reliability of the average amounts of WTP. The results of analysis were as follows. First, it was found that the WTPs for infrastructure under 1st influence area in target districts were estimated as 5,233won for road, 2,826won for parking lot, and 3,705won for park respectively. For the WTPs for infrastructure under 1nd area were estimated as 4,910 won for road, 2,242won for parking lot, and 3,620won for park respectively. Second, as the result of calculating the non-parametric WTP which built the 95% confidence interval, it was found that the all WTPs except the WTP for parking lot were fell into the 95% confidence interval. Third, as the result of calculating yearly total sum of benefits that the residents would get from the 1st influence area and the 2nd influence area, it was found that Gumdeong-gol district were expected to get 62,376,472won-amounted benefits, and Juseong district, and Shinmok-gol district, and Hyeonam district would get 35,0778,016won, 26,886,560won, and 22,252,032won respectively.

A Study on the Species Distribution Modeling using National Ecosystem Survey Data (전국자연환경조사 자료를 이용한 종분포모형 연구)

  • Kim, Jiyeon;Seo, Changwan;Kwon, Hyuksoo;Ryu, Jieun;Kim, Myungjin
    • Journal of Environmental Impact Assessment
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    • v.21 no.4
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    • pp.593-607
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    • 2012
  • The Ministry of Environment have started the 'National Ecosystem Survey' since 1986. It has been carried out nationwide every ten years as the largest survey project in Korea. The second one and the third one produced the GIS-based inventory of species. Three survey methods were different from each other. There were few studies for species distribution using national survey data in Korea. The purposes of this study are to test species distribution models for finding the most suitable modeling methods for the National Ecosystem Survey data and to investigate the modeling results according to survey methods and taxonominal group. Occurrence data of nine species were extracted from the National Ecosystem Survey by taxonomical group (plant, mammal, and bird). Plants are Korean winter hazel (Corylopsis coreana), Iris odaesanensis (Iris odaesanensis), and Berchemia (Berchemia berchemiaefolia). Mammals are Korean Goral (Nemorhaedus goral), Marten (Martes flavigula koreana), and Leopard cat (Felis bengalensis). Birds are Black Woodpecker (Dryocopus martius), Eagle Owl (Bubo Bubo), and Common Buzzard (Buteo buteo). Environmental variables consisted of climate, topography, soil and vegetation structure. Two modeling methods (GAM, Maxent) were tested across nine species, and predictive species maps of target species were produced. The results of this study were as follows. Firstly, Maxent showed similar 5 cross-validated AUC with GAM. Maxent is more useful model to develop than GAM because National Ecosystem Survey data has presence-only data. Therefore, Maxent is more useful species distribution model for National Ecosystem Survey data. Secondly, the modeling results between the second and third survey methods showed sometimes different because of each different surveying methods. Therefore, we need to combine two data for producing a reasonable result. Lastly, modeling result showed different predicted distribution pattern by taxonominal group. These results should be considered if we want to develop a species distribution model using the National Ecosystem Survey and apply it to a nationwide biodiversity research.

Detection of Hepatitis C Virus by RIA, Recombinant Immunoblot Assay and Nested RT-PCR (RIA, Recombinant Immunoblot Assay 및 Nested RT-PCR에 의한 C형 간염바이러스 검출)

  • Kim, Jae-Soo;Kim, Jong-Wan;Lee, Yun-Tai
    • The Journal of Korean Society of Virology
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    • v.30 no.2
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    • pp.151-159
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    • 2000
  • Hepatitis C virus (HCV) is one of the important human pathogen that can cause acute and chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Recently, the third generation radiation immuno assay (RIA) method has been developed as a very sensitive test to detect anti-HCV antibody. However, false positive is the problem with RIA test. To solve this the RIA results were compared to those of 5-antigen recombinant immunoblot assay (5-RIBA) and reverse transcription-polymerase chain reaction (RT-PCR). Among 12,767 serum samples tested from clinic visitors, total 275 (2.2%) samples were antibody positive by RIA. RIBA was performed with 148 RIA positives cases but among them was shown eighty five was antibody positive and sixty three (42.6%) was negative result. However, nested RT-PCR test was shown also carried out with 43 positive, 6 intermediates and 25 negatives of RIBA. As a result of the nested RT-PCR results, HCV antigen were detected in RIBA positive, 33.3% (2/6) RIBA intermediate and 12% (3/25). Clinical syndrome of all 148 patients as a with chronic active hepatitis (46.0%), cirrhosis (18.9%), hepatocellular carcinoma (8.1%) and others (27.0%) and they were positive in reaction by RIA test. But RIBA positive patients with 34.9% of chronic active hepatitis, 18.6% of cirrhosis, 4.6% of hepatocellular carcinoma and 41.9% of others were detected to be positive case by nested RT-PCR.

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Optimum Condition and Color Mechanism for Gold Color Glaze in Diopside Crystallization (Diopside 금색 결정 유약의 발색 기구)

  • Kim, Gumsun;Lim, Seong-Ho;Lee, Byung-Ha
    • Korean Journal of Materials Research
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    • v.23 no.5
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    • pp.286-292
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    • 2013
  • Generally, the color gold has had a biased conception due to its traditional use. Thus, this bias has resulted in a lack of usage of golden glaze on ceramics and also a lack of extensive studies of such glazes. In this paper, optimum conditions and mechanism of formation of gold color crystallization glaze containing $Fe_2O_3$(hematite), which is developed for gold colors of ceramic glazes, were studied. Experimental result showed that there are pyroxene based on diopside and $TiO_2$ phase in the base of a crystallization glaze with a value of $TiO_2$ of 6 wt% confirmed by XRD and Raman Spectroscopy. When $Fe_2O_3$ was used as a colorant for the gold color, the $TiO_2$ peak became extinct and the intensity of the diopside peak was sharper. Feldspar of 60 wt%, talc of 20 wt% and limestone of 20 wt% were used as the starting materials and these were tested using a three component system. The best result of test was selected and extended to its vicinity as an experiment to determine $TiO_2$ and $Fe_2O_3$ contents. The glaze with $TiO_2$ of 6 wt% and $Fe_2O_3$ of 12 wt% addition showed stable pyroxene based diopside crystals and the development of gold color. This gold color was obtained with CIE-$L^*a^*b^*$ values of 51.27, 4.46, 16.15 (a grayish yellow brown color), which was gained using the following firing conditions: temperature increasing speed $5^{\circ}C$/min, holding for 1 h at $1280^{\circ}C$, annealing speed $3^{\circ}C$/min till $1100{\circ}C$, holding for 2 h at $1100{\circ}C$, and finally natural annealing.

Prevalence and Risk Factors of Myofascial Pain Syndrome on School Boys (청소년들에서 근막동통증후군의 유병률과 위험요인)

  • Lim, Hyun-Sul;Lee, Jong-Min;Kim, Duck-Soo
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.2
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    • pp.184-192
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    • 2000
  • Objectives : To inquire the prevalence and the risk factors for myofascial pain syndrome (MPS) on young boys in order to use these results as the fundamental data for the prevention of their MPS. Methods : For 7 days in May 1999, this research was taken on 489 male students ranging from 6th to 12th grade. We randomly selected a class for every group and from these classes we operated physical examinations, self-reported questionnaires and from a rehabilitation doctor, MPS test was taken. Thoracic kyphosis and lumbar lordosis were also taken by using the inclinometer. We defined MPS as a regional pain complaint, palpable taut band that is painful on compression. Results : The shoulder MPS prevalence of the subjects were 29.7 persons/100 persons. The statistics revealed that as grades went up, the percentage significantly increased in the MPS prevalence. As of case-control study, 145 students who were tested postive in all aspects were placed as cases, and 176 students who were perfectly normal as controls on risk factors. As a result of comparing the student groups who were stisfied with their chairs to the student groups were not satisfied, the taller showed a significantly higher odds ratio (p<0.01). By the multiple logistic regression test, we concluded that the MPS disease was prevailed far more in the students in the higher grades (Odds ratio: 1.16, 95% C.I.: 1.03-1.31), and also those who were dissatisfied with their chairs than in the ones who were satisfied (Odds ratio: 1.92, 95% C.I.: 1.17-3.17). Conclusions : Significant correlations showed between the MPS diagnosed group and the students who are dissatisfied with their chairs. As a result, more research and observation has to be made concerning this disease, and the desks and chairs should be adjusted to suit the student's physical standards.

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A Study on Development of Computer model for Evaluating the Effective Rainfall on Upland Soil (밭 토양에서의 유효강우량 산정을 위한 전산모델 개발에 관한 연구)

  • 고덕구;정하우
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.24 no.1
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    • pp.63-72
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    • 1982
  • To maintain an optimum condition for the plant growth on upland soil, the irrigation planning after the natural rainfall should be given enormous considerations on the rainfall effectiveness. This study has been intended to develop the computer model for estimating the effec- tiveness of the rainfall. The computer model should also estimated the infiltration due to the rainfall and the soil moisture deficiency at the root zone of the plant. For this purpose, the experiments of infiltration using rainfall simulator and the observations of the change of soil moisture content before and after rainfall were carried out. Needed input data for the developed model include final infiltration capacity and field capacity of the soil, porosity of the top soil, root depth of the plant, rainfall intensity and duration, and the Horton's decay coefficient. Among the needed input data for the developed model, final infiltration capacity and Horton's decay coefficient were determined by the experiments of infiltration. And from the result of the experiments, it is found that there is a great correlation between initial infiltration capacity and initial moisture content. And it is also found that the infiltration due to rainfall can be estimated with the Horton's equation. The developed model was tested by the experimental data with two rainfall intensities. Tests were conducted on the different root depths at each rainfall. Observed and estimated effective rainfalls were found to have great correlation. The result of the experiments showed that the effectiveness of the rainfall were 100%, so the comparisons were conducted by the comsumption rates of infiltration at each depth. The developed model can be also used for estimating the deficiency of rainfall, if the rainfall is not sufficient to the needed soil moisture. But, test was not carried out.

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