• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.770-775
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• 2009

최근 들어 인간 중심의 정보화 사회가 USN 기술의 발전과 더불어 사물 간에도 정보들이 유기적으로 결합되고 활용될 수 있는 유비쿼터스 컴퓨팅 사회로 급격히 변모하고 있다. 이러한 유비쿼터스 컴퓨팅 사회를 성공적으로 구축하기 위해서는 센서노드들로부터 수집되는 센싱 정보를 효율적으로 관리하고, 센서 네트워크 구성에 대한 추상화 기능을 지원하는 USN 센서노드, 센서 네트워크, USN 미들웨어, 그리고 USN 응용 서비스 등의 USN 핵심 기술이 반드시 필요하게 된다. 본 연구에서는 각종 USN 단말장치들로 발생되는 센싱 값들의 전송 이벤트를 처리하기 위해서 USN 및 RFID 단말장치로부터 전송되는 다양한 센싱 값들을 효율적으로 처리할 수 있도록 데이터의 추상화를 수행하는 프로세스를 설계한다.

• BMB Reports
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• 제35권4호
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• pp.371-376
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• 2002

The receptor activator of nuclear factor kappa B (RANK) is a member of the tumor necrosis factor (TNF) receptor superfamily. It plays a critical role in osteoclast differentiaion, lymph node organogenesis, and mammary gland development. The stimulation of RANK causes the activation of transcription factors NF-${\kappa}B$ and activator protein 1 (AP1), and the mitogen activated protein kinase (MAPK) c-Jun N-terminal kinase (JNK). In the signal transduction of RANK, the recruitment of the adaptor molecules, TNF receptor-associated factors (TRAFs), is and initial cytoplasmic event. Recently, the association of the MAPK kinase kinase, transforming growth factor-$\beta$-activated kinase 1 (TAK1), with TRAF6 was shown to mediate the IL-1 signaling to NF-${\kappa}B$ and JNK. We investigated whether or not TAK1 plays a role in RANK signaling. A dominant-negative form of TAK1 was discovered to abolish the RANK-induced activation of AP1 and JNK. The AP1 activation by TRAF2, TRAF5, and TRAF6 was also greatly suppressed by the dominant-negative TAK1. the inhibitory effect of the TAK1 mutant on RANK-and TRAF-induced NF-${\kappa}B$ activation was also observed, but less efficiently. Our findings indicate that TAK1 is involved in the MAPK cascade and NF-${\kappa}B$ pathway that is activated by RANK.

• 의학교육논단
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• 제24권3호
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• pp.240-249
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• 2022

This study explored the public's response to an incident involving publicity about how physicians broke bad news to a terminal cancer patient by analyzing 1,960 comments from three online news websites that reported on this event using Braun and Clarke's theme analysis methods. Three themes and 10 subthemes emerged from the public's responses to the way the physicians broke the bad news. Theme 1 (a physician is a person who tells the facts) contained the following subthemes: physicians are responsible for delivering facts, but it is a matter of consideration for patients to deliver bad news to them, empathy and consolation should be expected from people other than physicians, and physicians who say what patients want to hear are cheaters. Theme 2 (there is a problem with physicians) included the following subthemes: the physicians' empathy or personality and problems with their communication methods. Theme 3 (there are obstacles to communication with dying patients) had the following subthemes: physicians become emotionally dull and find it very stressful to break bad news, giving hope to dying patients can lead to medical disputes, and empathy and consolation are also costly. When breaking bad news, the physicians delivered factual information, but they did so inappropriately, and emotional support for the patient was insufficient. In medical communication education, it is necessary to emphasize training in emotional support. In the medical field, an environment should be created where physicians can communicate as they have learned.

• 인터넷정보학회논문지
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• 제14권3호
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• pp.35-46
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• 2013

모바일 단말 환경이 활성화되면서 안드로이드 플랫폼을 탑재한 상용 모바일 단말이 널리 보급되고 있다. 최근 안드로이드 기반 모바일 단말에서 보안 취약성이 발견되면서 악성 어플리케이션을 통한 공격이 급증하고 있다. 대부분의 악성 어플리케이션은 오픈 마켓 또는 인터넷을 통해 배포되며 어플리케이션 내에 악성코드가 삽입되어 있어 단말 사용자의 SMS, 전화번호부, 공인인증서 등 개인정보와 금융정보 등을 외부 서버로 유출시키는 공격을 시도한다. 이에 따라 상용 모바일 단말에 대한 보안 취약점 분석과 그에 따른 능동적인 대응 방안이 필요하다. 이에 본 연구에서는 최근 급증하는 악성 앱에 의한 피해를 최소화하기 위해 다수의 모바일 단말서 발생하는 이벤트 수집을 통해 모바일 단말 내에서 실행되는 악성 어플리케이션에 의한 공격을 탐지하는 시스템을 설계 및 구현하였다.

• 한국빅데이터학회지
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• 제5권1호
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• pp.181-188
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• 2020

급증하는 항공 여객의 성장세에 맞춰 여객 터미널의 규모가 대형화됨에 따라 출발, 도착, 환승 여객들이 소지한 수하물을 최단 시간 내에 신속, 정확하게 처리할 수 있는 다양한 데이터 기술들이 접목된 첨단 수하물 처리시스템(Baggage Handling System; 이하 BHS)이 필수 요소가 되었다. 따라서 본 연구에서는 공항 수하물 처리시스템 운영의 고도화를 위해, 프로세스 관점의 데이터 분석 방법론을 통한 국내 공항의 수하물 처리능력 분석 방법을 소개하고, 이벤트 로그 기반 주요 지점의 정확한 부하예측 방법을 제시하여, 자원의 선제적 배치 및 flight-carrocel 스케줄링 최적화 문제 등 향후 첨단화된 BHS 운영 전략으로 이어질 수 있도록 한다. 분석에 사용된 데이터는 공공데이터 포털에서 얻을 수 있는 '전국 공항 수송실적', '항공기 운항 정보' API를 활용하였다. 국내 공항 BHS 시뮬레이션 모델에 해당 방법을 적용한 결과, 높은 수준의 예측성능을 확인 할 수 있었다.

• Molecules and Cells
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• 제25권1호
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• pp.86-90
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• 2008

Caspase-3 (CASP3) plays a key role in apoptosis. In this study, HAX-1 was identified as a new substrate of CASP3 during apoptosis. HAX-1 was cleaved by CASP3 during etoposide-(ETO) induced apoptosis, and this event was inhibited by a CASP3-specific inhibitor. The cleavage site of HAX-1, at $Asp^{127}$, was located using N-terminal amino acid sequencing of in vitro cleavage products of recombinant HAX-1. Overexpression of HAX-1 inhibited ETO-induced apoptotic cell death. It also inhibited CASP3 activity. Together, these results suggest that HAX-1, a substrate of CASP3, inhibits the apoptotic process by inhibiting CASP3 activity.

• BMB Reports
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• 제35권5호
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• pp.508-512
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• 2002

Phospholipase C-gamma-2 ($PLC{\gamma}2$) activation is a key signaling event for many cell functions. In order to delineate the pathways that lead to $PLC{\gamma}2$ activation, we devised a quick method for obtaining sufficient $PLC{\gamma}2$. We obtained the full-length cDNA for human $PLC{\gamma}2$ and expressed it in E. coli using the expression vector pT5T. To enhance the protein expression, tandem AGG-AGG arginine codons at the amino acid positions 1204-1205 were replaced by CGG-CGG arginine codons. The protein expression was detected in a Western blot analysis by both anti-$PLC{\gamma}2$ antibodies and the antibodies that are raised against the tripeptide epitope (Glu-Glu-Phe) tag that are genetically-engineered to its carboxyl terminal. Crude lysates that were prepared from bacteria that express $PLC{\gamma}2$ were found to catalyze the hydrolysis of phosphatidylinositol 4,5 bisphosphate. Similar to previous reports on $PLC{\gamma}2$ that is isolated from mammalian tissue, the recombinant enzyme was $Ca^{2+}$ dependent with optimal activity at 1-10 uM $Ca^{2+}$.

• 한국위성정보통신학회논문지
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• 제7권3호
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• pp.58-62
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• 2012

DMB 재난 경보 방송은 재난 발생 상황을 국민들에게 신속하고 효과적으로 전달하기 위해 T-DMB 망을 통해 서비스되고 있고, DGPS 보정 정보는 GPS 수신 데이터의 정확도를 향상시키기 위하여 개발된 것으로서 보편적인 사용을 위해 T-DMB 방송망을 통해 전송되는 것이 연구되고 있다. DGPS 보정 정보가 T-DMB 방송망을 통해 전송되므로 동일한 매체로 전송되는 재난 경보 메시지에 DGPS 보정 정보를 적용한다면, 재난이 발생한 지역을 보다 정확하게 지정할 수 있고 단말기에서는 재난 발생 위치의 정확한 측정이 가능하다. 따라서 본 논문에서는 T-DMB AEAS 메시지의 구조와 수신기에서 재난의 발생 위치를 측정할 수 있는 DGPS 정보를 이용한 T-DMB 재난 경보 방송 시스템 구현 방법을 제안한다.

• 디지털산업정보학회논문지
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• 제15권4호
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• pp.51-62
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• 2019

Recently, as the number of Smart Phone users increase, the simple payment system has been able to make payments using only card information such as a registered password without extra authorized certificate authentication or input of card information. In this paper, it will examine and analyze simple payment system provided by IT companies and financial institutions and the simple payment system that operates global online payment system by case view of operational direction. Then with this examination, it will study ways to improve the problems with terms of convenience and stability in terms of users. In this paper, it will analyze the inconvenient problem in using the QR code system that recently introduced and will propose solutions. Also, it will propose suggestions to solve inconvenience that caused by system that supports NFC simple payment terminal in Korea is not universalize by analyze case study on the overseas simple payment system. It will also propose opinions on the matters that customer having responsible for event of a small financial accident related to loss or theft when using the simple payment system. Then it will suggest expected requirements to prepare new security technical countermeasures and solve the conditions of meeting expectation satisfaction of users.

• 수산해양교육연구
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• 제29권2호
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• pp.354-364
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• 2017

This study tries to evaluate the effect of ITT introduction in Busan New Port. The study used the estimation model of the number of vehicles required in accordance with the backhaul rate. The model used big data, COPINO e-document for one year in 2015. COPINO recorded the event such as truck ID, container ID, ATA, damage etc when truck arrived at gate. The study finds important information to estimate the required number of trucks for handling current ITT containers in Busan New Port: Daily throughput in Busan New Port is 1650 vans, especially night throughput recorded peak level in 1800 hours to 2400 hours, the throughput between adjacent terminals recorded high, i.e PNIT to HPNT. The transportation capability for 6 hours between terminals is from 4 vans to 7 vans. The required trucks are estimated 89 currently without considering peak level. If we change the back haul rate from current 20% to 40%, 60% and 80%, how much would the cost drop? It was discovered that, if it is raised to 40%, 60% and 80%, the number of vehicle required will be reduced from 89 (current) to 76, 65 and 59. It was also discovered that the total savings will reduce down to 12%, 25% and 34%.