Background: c-Kit is a proto-oncogene that encodes a tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker for demonstrating thrombocyte function. We aimed to investigate whether c-kit is expressed in benign, preneoplastic and neoplastic endometrial tissues and whether MPV has a relation with c-kit expression and its intensity. Materials and Methods: c-Kit expression was investigated immunohistochemically in 10 samples of normal endometrium (n=10), simple endometrial hyperplasia (5 cases with atypia and 10 cases without atypia), complex endometrial hyperplasia (10 cases with atypia and 10 cases without atypia) and endometrial cancer (EC) (10 cases grade I and 10 cases grade II) and MPV of all cases was checked. Results: c-Kit expression was observed at very low rates in cases with normal endometrial tissues (NE) and in hyperplasia without atypia. c-Kit expression and immunostaining were strong in endometrial atypia and EC. MPV levels of complex atypical endometrial hyperplasia (CAEH) (p:0.002), EC grade I (ECG I) (p<0.001) and EC grade II (ECG II) (p<0.001) were significantly elevated when compared with the NE group. Both c-kit expression and intensity of immunostaining had a positive correlation with MPV level. Conclusions: While c-kit expression and intensity of immunostaining were mildly positive in NE and hyperplasia without atypia, they were clearly observed in EC and hyperplasia with atypia. As c-kit expression is related to the mutagenesis a long-term followup may be needed in these cases. A high MPV level may be a good test for demonstrating c-kit expression and intensity of immunostaining.
Recently, an increase in the occurrence of sudden local flooding of great volume and short duration due to global climate changes has occasioned the significant danger and loss of life and property in Korea as well as most parts of the world. Such a local flood that usually occurs as the result of intense rainfall over small regions rises quite quickly with little or no advance warning time to prevent flood damage. To prevent the local flood damage, it is important to quickly predict the flood severity for flood events exceeding a threshold discharge that may cause the flood damage for inland areas. The aim of this study is to develop the NFI (New Flood Index) measuring the severity of floods in small ungauged catchments for use in local flood predictions by the regression analysis between the NFI and rainfall patterns. Flood runoff hydrographs are generated from a rainfall-runoff model using the annual maximum rainfall series of long-term observations for the two study catchments. The flood events above a threshold assumed as the 2-year return period discharge are targeted to estimate the NFI obtained by the geometric mean of the three relative severity factors, such as the flood magnitude ratio, the rising curve gradient, and the flooding duration time. The regression results show that the 3-hour maximum rainfall depths have the highest relationships with the NFI. It is expected that the best-fit regression equation between the NFI and rainfall characteristics can provide the basic database of the preliminary information for predicting the local flood severity in small ungauged catchments.
Ha, Seung-Ryong;Hyun, Chang-Taek;Son, Myung-Jin;Kim, Yun-Sik
Korean Journal of Construction Engineering and Management
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v.12
no.4
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pp.29-39
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2011
In Korea, many mixed-used development projects(MXD) in mega project size are currently active. As these mega projects require long-term construction and execution and involve by different subjects in different fields, their completion breeds various problems, such as conflicts among project participants due to their complicated interest relationships and inaccuracy in predicting the economic performance of the projects due to inappropriate facility capacity planning. To solve these problems, it is essential to apply value engineering (VE) at the planning phase of the project, which can result in the best possible cost reduction and improvement of project performance. However, not many projects are actually implementing VE because of the lack of available information, as well as the limitations due to uncertainty in the early period of project execution. Therefore, this study aimed at proposing VE Team Building, Quality Model Performance Indexes, Space Model so as to resolve common mega project problems and overcome VE application limitations at planning stage. The result of this study is expected that the data can be utilized as basic data to apply VE at the planning phase of the large complex projects.
Journal of the Korean association of regional geographers
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v.23
no.2
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pp.239-256
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2017
This research is a theoretically grounded empirical study aimed at shedding light on the policy evolution of Technology Park(TP) in term of historical institutionalism in South Korea for the 16 years. The study analysed the evolution of TP, and the empirical fieldwork was completed in two regions, Gyeongsangbuk-do ana Daegu City. Historically the policy can be divided into three periods being affected by endogenous and exogenous impact. This research found that the functions of local TPs changed as following: six functions decided by central governments ${\rightarrow}$ added the role of supporting regional innovation ${\rightarrow}$ comprehensive support for small & medium-sized enterprise. Analysis of the empirical study reveals significant findings: first, the relationships between central government and local actors which was built in the quickening period have been path dependency. Second, the functions of local TPs were evolved with the characteristics of layering and reorientation of the institutions. Thirdly, there were some differentiation between the two regions because of the milieu, though the central government had the power deciding the functions.
The basic purpose of this study is to investigate service quality and relationship quality affecting the result of long-term relationship between service buyers and suppliers. This research presented a constructive model(service quality${\rightarrow}$relationship quality${\rightarrow}$customer's revisiting intention) and then propose the research model base on prior researches and studies about relationships among components of service. Data were gathered from respondents who visit traditional markets. For this study, data were analyzed by SPSS and AMOS 5.0. Data were gathered from 209 respondents in the Korean traditional market. This research proposed 6 hypotheses on 5 latent variables and tested through structural equation modeling. 5 alternative measurements were compared through statistical significance test of the paths of research model and the overall fitting level of structural equation model. and the result was successful. The results of the study indicate that service quality is properly modeled as an antecedent of relationship quality and revisiting intentions. We also discussed managerial implications of the study and its limitations.
In a power-asymmetry relationship like franchise system, a high dependent franchisee must often rely on its powerful partner. Therefore, in order to build up 'win-win' systems, therefore channel members should increase trust and commitment each other to enhance the relationship quality to sustain long-term cooperative relationships. First of all, to increase the relationship quality in franchise system, franchisor should increase franchisee's perception of the powerful franchisor's justice. The point of this research, I established basic hypotheses and comparative hypotheses to examine franchisor's behavior what franchisee expected which influences on franchisee's attitude and behavior in power - asymmetry relationship in franchise system. For the purpose of the empirical testing, managers of franchisee in the food service industry of Korea had been selected and analyzed, and major findings in this study as follow: First, the relational norm between franchisor and franchisee increased both distributive justice and procedural justice, especially relational norm had more effect on procedural justice than distributive justice. Second, distributive justice increased both economic commitment and social commitment while procedural justice just increased social commitment only but economic commitment. So, on the relational commitment, distributive justice was more important element than procedural justice. On the other hand, procedural justice had indirect effect on economic commitment through distributive and social commitment.
This paper suggests how Korean housemaids, called Sikmo, and Korean-Chinese migrant domestic workers have similar class positions and therefore form a dual identity in their interactions with female employers. rough spoken stories of the experiences of 27 females from Seoul, including Korean-Chinese domestic workers, Korean housemaids, and their employers, this research effectively overcomes the dichotomous discourse of natives versus foreigners. Instead it suggests the new interpretation that it is not foreignness but class inferiority of the domestic workers that plays a key role in establishing relationships with employers. Korean housemaids and Korean-Chinese domestic workers, both groups of whom are migrant workers, have developed coping strategies to enhance their labor value by spatially relocating themselves from their home society to a new society. They possess a similar labor status in women's history, being of low income, low education, and rural births. Consequently, these women experience 'translocal anchoring,' meaning their identities are intertwined with that of their home societies, and employers perceive them based on the characteristics of these places. The Korean employers perceive that the domestic workers' morality and intellectuality are inferior based on their class differences. This stigmatizing process leads employers to regard domestic workers as ambivalent people, not only threatening outsiders but also objects of pity, needing love and protection of their employers. The employers educate them culturally, teaching them skills to survive in the urban environment. These skills include cooking and language, in addition to advice on long-term plans to blend into society.
Commonly to design a database system. a conceptual database has to be designed and then it is transformed into a logical database schema prior to building a target database system. This paper proposes a method which transforms a Temporal Entity-Relationship Model(TERM) into a Temporal Object-Oriented Model(TOOM) to build an efficient database schema. I formalize the time concept in view of object versioning and specify the constraints required during transformation procedure. The proposed transformation method contributes to getting the logical temporal data from the conceptual temporal events Without any loss of semantics, Compared to other approaches of supporting various properties, this approach is more general and efficient because it is the semantically seamless transformation method by using the orthogonality of types of objects, semantics of relationships and constraints over roles.
The summit meeting of the South North Korean leaders was a turning point in the relationships between the two countries. It was followed by the Red-Cross Meeting, Minister-Level Meeting, economic agreements, which have increased the relationship more colorful in both quantities and qualities. However, the half-century period for separation was too long to overcome all the problems by only one event. The two countries have quite different social systems; one politically strong person is governing the North, while many interest groups are involved in political decision making processes in the South. In short, it would take a long time to settle down all the problems residing between the two countries. A system dynamics model is developed to describe the long term dynamics of the relations between the South and North Koreas. As a first attempt, the model focuses only on the diplomatic meeting issues between the South and North. The model aggregates diplomatic issues into 5 categories; economic issues, security issues, infrastructure, cultural issues, and past problems. It assumes that there would not be any dramatic changes between the two countries. It is a conceptual model composed of around 200 variables, and should not be used as a forecast tool. However, it captures most of the logics discussed in the papers and conferences concerning the South and North Korea relations. Many sensitivity studies and Monte Carlo simulations have shown that the simulation results matches with mental models of experts; that is the model can be used as a learning tool or as a secondary opinion until the data required by the model is collected. In order to analyze the current situation, five scenarios are simulated and analyzed; the functional approach, the conditional approach, the balanced approach, the circumstantial approach, and the strategic approach. The functional approach represents that the South makes efforts in the area where the possibility of agreement is high for the next 10 years. The conditional approach is a scenario where the South impose all difficult issues as conditions for resolving other diplomatic issues. The balanced approach is resolving the five issues with the same priorities, while the circumstantial approach is resolving issues which seem to be resolved easily. Finally, another optimum approach has been seek using the system dynamics model developed. The optimum strategy (it is named as the strategic approach) was strikingly different from other four approaches. The optimum strategy is so complicated that no one could find it with mental model(or by just insights). Considering that the system dynamic model used to find the optimum is a simplifind (maybe over simplified) version of the reality, it is concluded that a well designed system dynamics model would be of great help to resolving the complicated diplomatic problems in any kind.
Journal of The Korean Association For Science Education
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v.21
no.1
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pp.13-21
/
2001
This study examined the influences of project activities based on multiple intelligences to science achievement of elementary school children. The proportions of variance of science achievement explained by General Intelligence(GI) and Multiple Intelligences(MI) were analyzed, then the influences of project activities, which used various aspects of MI were investigated. Two classes of grade 5 at Pusan in Korea were selected for the study. On the basis of science achievement of prior term, the subjects were classified into upper-, average-, and lower-achievement groups. GI and MI were measured for each child, and the relationships of these measures with prior science achievement were analyzed using multiple regression analyses. In order to investigate the effects of the project activities on science achievement, the classes were divided into the control and experimental groups, which the former group learned science topics using the traditional teaching and learning method and the latter group performed the projects about the same topics using their own multiple intelligences. Then, their achievements were analyzed by ANOVA. Results showed that the proportion of variance explained by MI was higher about two times than that of explained by GI. Project activities contributed to the improvement of science achievement of average and upper achievers, however, in the case of under achievers, this effect was not statistically significant.
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