• Structural Monitoring and Maintenance
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• v.9 no.4
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• pp.323-336
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• 2022

Steel truss bridge is one of the most widely used bridge types in Indonesia. Out of all Indonesia's national roads, the number of steel truss bridges reaches 12% of the total 17,160 bridges. The application of steel truss bridges is relatively high considering this type of bridge provides advantages in the standardization of design and fabrication of structural elements for typical bridge spans, as well as ease of mobilization. Directorate of Road and Bridge Engineering, Ministry of Works and Housing, has issued a standard design for steel truss bridges commonly used in Indonesia, which is designed against the design load in SNI 1725-2016 Bridge Loading Standards. Along with the development of actual traffic load measurement technology using Bridge Weigh-in-Motion (B-WIM), traffic loading data can be utilized to evaluate the reliability of standard bridges, such as standard steel truss bridges which are commonly used in Indonesia. The result of the B-WIM measurement on the Central Java Pantura National Road, Batang - Kendal undertaken in 2018, which supports the heaviest load and traffic conditions on the national road, is used in this study. In this study, simulation of a sequences of traffic was carried out based on B-WIM data as a moving load on the Australian type Steel Truss Bridge (i.e., Rangka Baja Australia -RBA) structure model with 60 m class A span. The reliability evaluation was then carried out by calculating the reliability index or the probability of structural failure. Based on the analysis conducted in this study, it was found that the reliability index of the 60 m class Aspan for RBA bridge is 3.04 or the probability of structural failure is 1.18 × 10^-3, which describes the level of reliability of the RBA bridge structure due to the loads from B-WIM measurement in Indonesia. For this RBA Bridge 60 m span class A, it was found that the calibrated nominal live load that met the target reliability is increased by 13% than stated in the code, so the uniform distributed load will be 7.60 kN/m² and the axle line equivalent load will be 55.15 kN/m.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.1
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• pp.495-505
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• 2014

The retention basin is a river-facility for the flood mitigation by storing the river flow temporarily. The new 3 retention basins are installed in these regions YeoJu, NaJu, YoungWol by the Large River Management Project. In this study, 1D and 2D numerical flow simulation are conducted to evaluate the reduction effect of the peak flood stage for the YeoJu retention basin. HEC-RAS and FLDWAV models are used for 1D simulation with the option of retention basin. CCHE2D model is used for 2D simulation with the same hydrograph used in 1D simulation. It is verified that the peak flood stage is reduced very largely about 0.13 m near the overtopping section of the levee in 1D simulation. It is verified that the peak flood stage is reduced very largely about 0.20 m at the upstream-end of the simulated reach in 2D simulation. 2D simulation for the retention basin is more reasonable because physical characteristics of topography in the model, and also more advantageous for the evaluation of the flow characteristics of the in- and outside of the retention basin on the results of simulation of this study.

• Quality Improvement in Health Care
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• v.12 no.2
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• pp.113-123
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• 2006

Objective : This research is focused on understanding the current status of the Health Smart Card already in use in other advanced countries. This research will analyze the current status of the medical institutions Health Smart Card system adoption process and its effects, and provide a basis for future policy decisions for the effective adoption and diffusion of a Health Smart Card system, in the medical field, through the completed research and analysis. Method : This research surveys the domestic, and foreign, status of Health Smart Card usage. The research also presents up-to-date methodology for the evaluation of the effects of medical and health care technology. The research also conducts a survey of the domestic medical institutions that have implemented a Health Smart Card system, and then analyzes the results of the survey. Additionally, the research carried out a survey and analysis of medical institutions with no Health Smart Card system implemented, and considered the factors affecting the diffusion of Health Smart Card systems in considering an effective policy for the introduction and diffusion of such a system. Research Results : Through the study of the methodology of medical and health care information technology in advanced countries, the methodology for assessing Health Smart Card technology has been established, and focuses on 6 aspects. The study on the status of foreign implementation has shown a model for the Health Smart Card system. A survey was conducted on the current status of medical institutions with an implemented Health Smart Card system, and the survey results have been analyzed. Also, factors influencing the adoption of Health Smart Card systems have been analyzed through the survey on those medical institutions that have not implemented a Health Smart Card system. Conclusion : The government must provide institutional measures for sharing medical records by constructing an IT infrastructure at the national level to enable the adoption and diffusion of a Health Smart Card system. Such a network will make connections between medical institutions possible, thus making the diffusion of the Health Smart Card system nationwide. For the successful adoption and diffusion of a Health Smart Card system, a model system development, under a medical record sharing system, should be conducted. Additionally, a regional unit based model should be developed for the model project, as is done in advanced countries, along with the application of such results.

• Environmental Analysis Health and Toxicology
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• v.31
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• pp.10.1-10.8
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• 2016

Objectives Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic effects like the aromatase inhibitors, the effects of EGb761 on steroidogenesis have not been studied yet. Therefore, the effects of EGb761 on steroidogenesis and aromatase activity was studied using a H295R cell model, which was a good in vitro model to predict effects on human adrenal steroidogenesis. Methods Cortisol, aldosterone, testosterone, and $17{\beta}$-estradiol were evaluated in the H295R cells by competitive enzyme-linked immunospecific assay after exposure to EGb761. Real-time polymerase chain reaction were performed to evaluate effects on critical genes in steroid hormone production, specifically cytochrome P450 (CYP11/ 17/19/21) and the hydroxysteroid dehydrogenases ($3{\beta}$-HSD2 and $17{\beta}$-HSD1/4). Finally, aromatase activities were measured with a tritiated water-release assay and by western blotting analysis. Results H295R cells exposed to EGb761 (10 and $100{\mu}g/mL$) showed a significant decrease in $17{\beta}$-estradiol and testosterone, but no change in aldosterone or cortisol. Genes (CYP19 and $17{\beta}$-HSD1) related to the estrogen steroidogenesis were significantly decreased by EGb761. EGb761 treatment of H295R cells resulted in a significant decrease of aromatase activity as measured by the direct and indirect assays. The coding sequence/Exon PII of CYP19 gene transcript and protein level of CYP19 were significantly decreased by EGb761. Conclusions These results suggest that EGb761 could regulate steroidogenesis-related genes such as CYP19 and $17{\beta}$-HSD1, and lead to a decrease in $17{\beta}$-estradiol and testosterone. The present study provides good information on potential therapeutic effects of EGb761 on estrogen dependent breast cancer.

• Korean Journal of Food Science and Technology
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• v.47 no.1
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• pp.111-118
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• 2015

In the present study, the phenolic compound level, antioxidant activity, and inhibition of lipid accumulation in Aspergillus oryzae-fermented water extracts of the Platycodon grandiflorum (PG) root and the Curcuma longa (CL) root were determined. Total polyphenol and flavonoid contents were decreased after fermentation. However, the flavonoid content of the fermented PG (FPG) was increased by 2.9-fold that of the PG before fermentation. In addition, the antioxidant activities were significantly decreased following fermentation. The potential anti-obesity activity was assessed by determining lipid accumulation and mRNA expression of sterol regulatory element-binding protein 1c (SREBP-1c) and peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) in 3T3-L1 cells. Aspergillus-fermented extracts of PG and CL roots decreased lipid accumulation, and mRNA expression of SREBP-1c and $PPAR{\gamma}$ in 3T3-L1 cells. These results indicate that Aspergillus fermentation augments the anti-obesity activity of PG and CL by regulating the expression of the genes involved in lipid accumulation and cell differentiation of 3T3-L1 cells.

• Food Science and Preservation
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• v.21 no.6
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• pp.917-924
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• 2014

Normal- and late-harvested Fuji apples were fermented using the rapid-fermenting yeast strain Saccharomyces cerevisiae SS89. The late-harvest apples showed a slightly higher soluble-solid content with a lower level of total-acid and moisture (p<0.05) contents as well as hardness (p<0.05) than the normal-harvest apples. During the fermentation, the apples had similar changes in the pH and total-acid content regardless of the harvest time, but the increases in the alcohol content and yeast viable count with the decrease of the soluble-solid content were more rapid in the late-harvest apples than in the normal-harvest apples. After the completion of the fermentation, the soluble-solid and alcohol contents became very similar. The late-harvest cider showed a high total phenolic-compound content and a high DPPH radical scavenging effect, although these were slightly lower than those of the normal-harvest cider. It also showed a higher malic-acid content and higher hue color (p<0.05), Hunter's L, and b (p<0.05) values than the normal-harvest cider. In the sensory evaluation, the late-harvest cider obtained a higher score in taste and a lower score in color compared to the normal-harvest cider.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.40 no.4
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• pp.429-435
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• 2020

North Korea declared itself complete with nuclear force after its sixth nuclear test in 2017. Despite efforts at home and abroad to denuclearize the Korean Peninsula, the prospects for the denuclearization are not bright. Along with political and diplomatic efforts to deter NK's WMD threats, the government is required to strengthen its consequence management capabilities against 'catastrophic situations' expected in case of emergency. Accordingly, this study was conducted to present measures to strengthen follow-up management against CBRN threats. The research model was partially supplemented and utilized by the THIRA process adopted and utilized by the U.S. Department of Homeland Security among national-level disaster management plan development models. Korea's consequence management (CM) system encompasses risk and crisis management on disaster condition. The system has been carried out in the form of a civil, government and military integrated defense operations for the purpose of curbing the spread or use of CBRNs, responding to threats, and minimizing expected damages. The preventive stage call for the incorporation of CBRN concept and CM procedures into the national management system, supplementing the integrated alarm systems, preparation of evacuation facilities, and establishment of the integrated training systems. In the preparation phase, readjustment of relevant laws and manuals, maintenance of government organizations, developing performance procedures, establishing the on-site support systems, and regular training are essential. In the response phase, normal operations of the medical support system for first aid and relief, installation and operation of facilities for decontamination, and development of regional damage assessment and control guidelines are important. In the recovery phase, development of stabilization evaluation criteria and procedures, securing and operation of resources needed for damage recovery, and strengthening of regional damage recovery capabilities linked to local defense forces, reserve forces and civil defense committees are required.

• Journal of Korea Water Resources Association
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• v.45 no.8
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• pp.743-753
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• 2012

AWS data can be used effectively to understand the rainfall characteristics in Korea. In spite of this advantage, AWS data have been used restrictively in flood control analysis and the study on water use analysis such as water balance assessment is very insufficient. In this study, AWS data are used to analyze spatial rainfall characteristics quantitatively and water balance assessment is performed based on AWS data. Water balance assessment is carried out from year 2002 to year 2010 considering water supply networks in Korea. The analysis shows that year 2009 is the driest year during 9 years (2002~2010) and the regions with low level water supply reliability are concentrated in the west coast of Jeonnam and the upper region of the Nakdong River. As a result, the regions that have a lack of available water resources such as the coastal and insular areas are vulnerable to droughts. Therefore, regional water supply and management plans are urgently needed. Additionally, AWS data, which consider rainfall characteristics of the coastal and insular areas, can be useful in water balance assessment.

• Food Science and Preservation
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• v.17 no.4
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• pp.451-456
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• 2010

We investigated changes in the quality of pulp-containing apple juice, during storage, after addition of various amounts of vitamin C, which was stable over time. Neither sugar content nor acidity level varied when vitamin C was added. The pH was slightly lower (pH 4.29-4.30) in juice with added vitamin C than in unsupplemented juice (pH 4.40). The L and b color values fell as vitamin C content rose and the storage period was extended. In sensory evaluation tests, taste and overall acceptability were higher for juice to which vitamin C had been added to 0.02% (w/v) than for unsupplemented juice. Vitamin C levels fell less during storage at $4^{\circ}C$ than at higher temperatures. The alcohol-soluble color (ASC) value fell as the amount of added vitamin C rose, and tended to be lower when juice was stored at $4^{\circ}C$ compared to $37^{\circ}C$. In summary, apple juice containing pulp was optimally stored at $4^{\circ}C$ after addition of 0.02% (w/v) vitamin C

• Economic and Environmental Geology
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• v.47 no.3
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• pp.291-302
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• 2014

The Chinese government and its agencies were trying in order to solve the unstability of resource supply and demand. Ministry of Land and Resources of China(MLR) carried out a lot of national-level policy and planning for estimating the domestic mineral and energy resources potential and recoverable reserves, as the Chinese land and resources survey plan(1999~2010), the Chinese mineral resource survey and exploration plan(2008~2020), announcement for shale gas industry policies of China, the Chinese shale gas resources evaluation and selection project for its development priority areas(2012), and the plan for Chinese shale gas development(2011~2015). The two large sedimentary basins of Chinese shale gas reserves are Sichuan and Tarim basins with excellent potential, accounting for majority of the estimated national reserves. Recoverable gas-bearing shale of China was surveyed to be widespread. The volume of recoverable shale gas reservoirs in China has been estimated to be around 31 trillion cubic meters(1,115 trillion cubic feet). China is one of only three countries with the US and Canada to produce shale gas in commercial quantities. China is concentrating on technology development to enhance commercial production of shale gas, and on survey and exploration activities to increase its recoverable reserves. The trends related to shale gas development and R&D activities in China to respond to changes in international oil market should be actively monitored based on analysis of Chinese policies and technology.