• Mass Spectrometry Letters
• /
• 제6권2호
• /
• pp.38-42
• /
• 2015

Roflumilast analogs are a group of drugs which act as selective photodiesterase (PDE-4) inhibitor for the treatment severe chronic pulmonary disease associated with chronic brochnonities. Structural identification of degradation products using high resolution mass spectrometry and theoretical investigation by density functional theory have been successfully carried out on roflumilast to identify four degradation products namely, 3,5-dichloropyridin-4-amine, N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-hydroxy benzamide, N-(3,5-dichloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy) benzamide and 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxidopyridin-4-yl)-4-(difluoro methoxy) benzamide, generated in alkali, acidic and oxidative conditions.

• 조명전기설비학회논문지
• /
• 제27권7호
• /
• pp.101-107
• /
• 2013

IEC Standards on lightning protection system specify the use of natural components as down conductors. This paper provides an analysis of problems revealed from our field investigation and survey conducted for the relevant experts in the construction site where natural components are used as down conductors. It also considers a suitable condition for installing natural components as down conductors in accordance with the latest version of the standard. As a result, when rebars of reinforced concrete are used as down conductors, vertical bars consisting of rebars of which thickness is not less than D13($127mm^2$) should be connected by welding, clamps or bound joints, using appropriate connection components conforming to IEC Standards. The lashed joints, however, shall not be applied for down conductors.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.431-439
• /
• 2003

The problem of detecting individual differences of chemically similar liquids remains to be unsolved for various areas of the natural sciences, such as medicine, biology, nutrition, and cosmetics 1. This problem is of crucial importance for the cosmetic sciences, including perfumery and aromatherapy. For example, some certain subtle differences of smell and taste between chemically similar liquids are very difficult to detect by using conventional methods of analysis, such as gas chromatography (GC) and the like (except under unique advanced techniques that are expensive, time consuming, and are not readily available). However, a trained human nose and! or mouth of a perfumer and/ or taster can detect differences of that kind. There are two conventional ways to make a fragrance.(omitted)

• 대한용접접합학회:학술대회논문집
• /
• 대한용접접합학회 2008년도 춘계학술발표대회 개요집
• /
• pp.6-6
• /
• 2008

• Smart Structures and Systems
• /
• 제4권2호
• /
• pp.171-182
• /
• 2008

In this paper, a methodology for the estimation of masonry elasticity and shear moduli is presented, for linear elasticity considerations. The methodology is based on the assumption that for a "periodic" masonry wall, which is formed by the repetition of a basic unit containing blocks and mortar, the mechanical characteristics of the unit are representative of the characteristics of the entire wall. For their calculation, the finite element analysis method is used. A micro-model with finite elements simulating separately the blocks and the mortar is developed. An equivalent finite element model, using an homogenous material is also developed and assuming equivalence of strains for the two models, the homogenous material properties are estimated. The efficiency of the method and its applicability limits are investigated.

• 열처리공학회지
• /
• 제23권2호
• /
• pp.75-82
• /
• 2010

A new advanced combined PVD/CVD technique of DLC film deposition has been developed. Deposition of a DLC film was carried out using a pulsed carbon arc discharge in vapor hydrocarbon atmosphere. The arc plasma enhancing CVD process promotes dramatic increase in the deposition rate and decrease of compressive stress as well as improvement of film thickness uniformity compared to that obtained with a single PVD pulsed arc process. The optical spectroscopy investigation reveals great increase in radiating components of $C_2$ Swan system molecular bands due to acetylene molecules decomposition. AFM, Raman spectroscopy, XPS and nano-indentation were used to characterize DLC films. The method ensures obtaining a new superhard DLC nano-material for deposition of protective coatings onto various industrial products including those used in medicine.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2003년도 봄 학술발표회 논문집
• /
• pp.193-196
• /
• 2003

In this paper, the experimental investigation for the setting properties of cement paste, the consistency and strength properties of mortar with steel furnace slag dust was performed and compared with those of cement paste and mortar with ground granulated blast furnace slag. When steel furnace slag dust was replaced with normal portland cement, setting time and flow value indicated to good results like as mortar with ground granulated blast furnace slag. However, mortar with steel furnace slag dust expressed to appreciably strength devaluation according to containing ratio, and did not indicate the pozzolanic reaction like as ground granulated blast furnace slag.

• 펄프종이기술
• /
• 제33권4호
• /
• pp.1-6
• /
• 2001

Today's paper industry tries to use greater amount of high yield pulp and recycled fiber and to close mill water system, which results in higher fines content and buildup of organic and inorganic contaminants in white water system. Researches are being focused to develop chemical additives that provide good retention and drainage in a closed papermaking system. A microparticle retention system consisted of cationic guar gum and anionic colloidal silica so has been developed to meet the requirements for improving machine speed and product quality. The objective of this investigation was to determine the effects of the degree of cationic guar gums, charge density and structure of anionic colloidal silica sols, and the degree of system closure on the performances of this microparticle retention system. Cationic guar gums and anionic colloidal silica sols with higher charge densities showed better retention performance. Particularly, wider maximum in retention was obtained when structure colloidal silica was used suggesting as mechanism of microparticle bridging is functioning in this system.

• 펄프종이기술
• /
• 제39권2호
• /
• pp.54-59
• /
• 2007

Cereal, computer software, wine, small appliances, and fast foods are examples of products that have switched from folding carton to microflute corrugated paperboard. Microflute corrugated paperboards have their unique wonderful packaging characteristics that are driving forces for people to use more and more. Good strength property, excellent shock absorbing ability, and beautiful outer appearance of microflute corrugated paperboards go hand and hand with their environmental advantages. It is known that physical properties of microflute corrugated paperboards depend on not only properties of base paper but corrugator operating conditions. This study was carried out to investigate on the corrugator's optimum operating conditions for making micro flute corrugated paperboards. Lab-scaled micro flute corrugator was installed and run with systematic changes of operation conditions to investigate the effects of operation conditions on physical properties of micro flute corrugated paperboards.

• Earthquakes and Structures
• /
• 제6권3호
• /
• pp.317-334
• /
• 2014

The work is concerned with an investigation of the advantages stemming from the use of lightweight aggregate concrete in earthquake-resistant reinforced concrete construction. As the aseismic clauses of current codes make no reference to lightweight aggregate concrete beams made of lightweight aggregate concrete but designed in accordance with the code specifications for normal weight aggregate concrete, together with beams made from the latter material, are tested under load mimicking seismic action. The results obtained show that beam behaviour is essentially independent of the design method adopted, with the use of lightweight aggregate concrete being found to slightly improve the post-peak structural behaviour. When considering the significant reduction in deadweight resulting from the use of lightweight aggregate concrete, the results demonstrate that the use of this material will lead to significant savings without compromising the structural performance requirements of current codes.