• Journal of Veterinary Clinics
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• v.12 no.1
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• pp.829-837
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• 1995

This study was performed to evaluate the effects of ocular bacteria and tear lactoferrin on the Tear Staining Syndrome(TSS) in poodle dogs. Staphylococcus, Klebsiella, Micrococcus and Pseudomonas were the most Prevalent microorganisms isolated in normal eyes of poodle dogs, whereas the predominant isolates in the poodle dogs with TSS were Micrococcus, Staptococcus and Staphylococcus. There were no significant differences between the normal and tear-stained poodle dogs in the quantity of tear lactoferrin. In vitro hair staining experiment, bacteria isolated from the eyes with TSS and lactoferrin didn't stain hair. The results have shown that either ocular bacteria or tear lactoferrins were not related to the TSS.

• Journal of Veterinary Clinics
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• v.25 no.2
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• pp.115-118
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• 2008

22 dogs (31 eyes) that had treated with trimethoprim-sulfamethoxazole for tear staining syndrome at Snoopy Pet Clinic from October 2000 to September 2002 were reviewed. Of the 22 dogs, 12 were female and 10 male. Their mean (${\pm}$ SD) age was 3.5 (${\pm}\;1.3$) years. The breeds of the dogs consisted of Maltese (8 dogs), Shih tzu (6 dogs), Poodle (5 dogs), Yorkshire terrier (2 dogs), and Mixed (1 dog). The dogs received 30 mg/kg trimethoprim-sulfamethoxazole perorally twice daily for two to six weeks. 26 (19 dogs) of the 31 eyes (22 dogs) recovered completely and did not show relapse at $26{\sim}30$ weeks after treatment. Any complications did not observed. Five eyes of three dogs were not cured. Two eyes (one dogs) of them had not response to medicament and three eyes (two dogs) recurrence but the clinical signs decreased. It was considered that the trimethoprim-sulfamethoxazole was effective for the treatment in dogs with tear staining syndrome.