• BMB Reports
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• v.42 no.6
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• pp.315-323
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• 2009

In order to elucidate ultimate biological function of the genome, the model animal system carrying mutations is indispensable. Recently, large-scale mutagenesis projects have been launched in various species. Especially, the mouse is considered to be an ideal model to human because it is a mammalian species accompanied with well-established genetic as well as embryonic technologies. In 1990', large-scale mouse mutagenesis projects firstly initiated with a potent chemical mutagen, N-ethyl-N-nitrosourea (ENU) by the phenotype-driven approach or forward genetics. The knockout mouse mutagenesis projects with trapping/conditional mutagenesis have then followed as Phase II since 2006 by the gene-driven approach or reverse genetics. Recently, the next-generation gene targeting system has also become available to the research community, which allows us to establish and analyze mutant mice carrying an allelic series of base substitutions in target genes as another reverse genetics. Overall trends in the large-scale mouse mutagenesis will be reviewed in this article particularly focusing on the new advancement of the next-generation gene targeting system. The drastic expansion of the mutant mouse resources altogether will enhance the systematic understanding of the life. The construction of the mutant mouse resources developed by the forward and reverse genetic mutagenesis is just the beginning of the annotation of mammalian genome. They provide basic infrastructure to understand the molecular mechanism of the gene and genome and will contribute to not only basic researches but also applied sciences such as human disease modelling, genomic medicine and personalized medicine.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.41 no.3
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• pp.11-20
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• 2018

Recently companies have increased the new projects to improve and innovate the business process in order to adopt the advanced technologies such as IoT (Internet of Things), Big Data Analysis, Cloud Computing, mobile and artificial intelligence technologies for sustainable competitive advantages under rapid technological and socioeconomic external environmental changes. However, there are obstacles to achieve the project goals, corporate's strategy and objectives due to various kind of risks based on characteristics of projects and conflicts of stakeholders participated on projects. Hence, the solutions are required to resolve the various kind of risks and conflicts of stakeholders. The objectives of this study are to investigate the impact of the project governance, agency conflicts on the project success based on agency theory by using the statistical hypothesis testing the relationship among those variables. As a result of hypothesis testing, we could find that the project governance impacts positively on project success and negatively on the agency conflicts. Further, the agency conflicts impacts negatively on the project success. Finally, we could find that the agency conflicts such as goal conflict, different risk attitude and information asymmetry between project manager and team members impact negatively on the project success. Meanwhile, the project governance impact positively on the project success, negatively impact on the agency conflicts such as goal conflict, different risk attitude and information asymmetry between project manager and project team members. In order to increase the project success rate, the project governance institutions such as PGB (Project Governance Board), EPMO (Enterprise Project Management Office), PSC (Project Steering Committee) are needed to prevent or reduce the agency conflicts between project manager and team members.

• Journal of Korean Society for Quality Management
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• v.51 no.2
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• pp.185-202
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• 2023

Purpose: The purpose of this study is to identify key performance evaluation items and factors that are effective and practical for project management of defense standard standard improvement projects, and to develop a quantitative performance evaluation model. Methods: For the development of a performance evaluation model for defense standard improvement projects, we analyzed past major project performance and derived evaluation items and factors. To increase the objectivity and efficiency of project evaluation, we developed an evaluation index that enables relative evaluation of evaluation targets, and calculated the main importance of evaluation items using the Analytic Hierarchy Process (AHP) method based on the main opinions of expert groups. Results: The study resulted in the identification of main performance items for defense standard improvement projects, which were classified into defense standard conformity review performance and defense standard improvement performance items. We also simplified the evaluation model by integrating various evaluation items into similar evaluation factors. Additionally, we developed a quantitative evaluation index that enables relative evaluation of the targets and verified the objectivity and validity of the suggested performance evaluation model by reevaluating it using performance data from past commissioned professional institutions Conclusion: Developing a quantitative evaluation model for defense standard improvement projects is expected to provide a means of measuring the effectiveness of the project, and to be used as a tool to determine the appropriateness and effectiveness of medium and long-term project plans.

• Proceedings of the Korea Information Processing Society Conference
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• 2017.11a
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• pp.464-465
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• 2017

본 논문에서는 애자일 방법론과 스크럼 기법에 대해서 소개하고 국내 SI프로젝트에 스크럼 기법을 적용하기 어려운 이유와 스크럼이 적용된 SI프로젝트를 성공적으로 완료하기 위한 가이드를 제안한다.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1154-1161
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• 2022

Building Information Modelling (BIM) has evolved into a comprehensive, collaborative method in construction project delivery. Most industrialized and developed countries have made BIM mandatory in the government and public projects, whereas developing countries are embracing and catching up BIM technologies to improve their professional's abilities and reduce claims in the construction projects. However, BIM awareness and professional's competence have become critical in implementing BIM in infrastructure projects in Nepal, particularly hydropower projects. The objectives of this study are to find the BIM awareness among hydropower professionals in Nepal and assess their response. The study used a questionnaire survey to assess the awareness. The results showed that only few professionals (12 percentage in this study) are aware of BIM and its application in Hydropower infrastructures. Majority of the respondents (more than 50%) were interested in BIM trainings and believed BIM implementation in future projects. The study indicated that lack of BIM training and lack of BIM awareness were the top factors affecting BIM implementation in hydropower projects in Nepal. The findings showed that about 66 percent of the respondents who used BIM in their projects mainly used during construction phase. More than 80 percent believed that BIM should be mandated for the hydropower projects in Nepal. The findings presented in this study could promote awareness among different professionals, organization, and construction team and encourage BIM implementation in Hydropower projects. The findings could raise awareness of BIM in Nepal's infrastructure sectors and its invaluable benefits in construction.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.259-262
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• 2015

Due to the labor-intensiveness, high investment cost, long execution time, frequent change orders, and many stakeholders in a BIM project, a BIM manager is bound to face a lot of risks to make decisions in cost managing process. Since the productivity of a BIM team will affect the execution cost, this study investigates a simple method of assessing the productivity of a BIM team using the working timesheet records of the team. In this research, the productivity of a BIM team is defined as the effective working floor area (in square meters) of BIM uses per labor-time (in man-months) spent by the team. After the applicability of this method is tested by regression analysis using data from 5 real BIM projects in the construction phase, it is found that the simple productivity definition adopted in the method, although easy-to-implement, does not produce a statistically constant productivity value. More research is therefore needed in the future to devise better indicator(s) for assessing the productivity of a BIM team.

• Communications of Mathematical Education
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• v.26 no.2
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• pp.155-176
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• 2012

In this paper, we present a practical and essential method of using team projects for calculus. We, specifically, take into account the team project that calculate the volume of lung represented on CT scan images. We have demonstrated that the process of analyzing the images in a team project encourage studying numerical methods of integration for calculus. Also, we have used various technological programs(MATLAB, MATHEMATICA, MS Excel) to solve the team project.

• Journal of Engineering Education Research
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• v.17 no.1
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• pp.20-25
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• 2014

This study investigated the mediating effect of engineering design self-efficacy on the relationship between self-leadership and perceived team creativity. Participants were 110 engineering college students pursuing team projects. Engineering design self-efficacy showed complete mediation effects on the relationships between perceived team creativity and self-reward and evaluating beliefs and assumptions. Partial mediation effect of engineering design self-efficacy was found on the relationship between perceived team creativity and natural reward. Finally, limitations of this study and suggestions for future studies were discussed.

• Journal of Korean Society of Rural Planning
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• v.30 no.2
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• pp.69-77
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• 2024

As impervious area increases due to urbanization, rainfall on the impervious area does not infiltrate into the ground, and stormwater drains quickly. Low impact development (LID) practices have been suggested as alternatives to infiltrate and store water in soil layers. The practices in South Korea is applied to urban development projects, urban renewal projects, urban regeneration projects, etc., it is required to perform literature research, watershed survey, soil quality, etc. for the LID practices implementation. Prior to the LID implementation at fields, there is a need to simulate its' effect on watershed hydrology, and Storm Water Management Model (SWMM) provides an opportunity to simulate LID practices. The LIDs applied in South Korea are infiltration-based practices, vegetation-based practices, rainwater-harvesting practices, etc. Vegetation-based practices includes bio-retention cell and rain garden, bio-retention cells are mostly employed in the model, adjusting the model parameters to simulate various practices. The bio-retention cell requires inputs regarding surface layer, soil layer, and drain layer, but the inputs for the drain layer are applied without sufficient examination, while the model parameters or inputs are somewhat influential to the practice effects. Thus, the approach to simulate vegetation-based LID practices in SWMM uses was explored and suggested for better LID simulation in South Korea.

• Journal of Wetlands Research
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• v.8 no.1
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• pp.97-106
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• 2006

This study discusses two canceled dam projects, Youngwol Dam in South Korea and Two Forks Dam in Colorado of the United States. Both of them illustrate how the new paradigm applies to regional water projects because they became victims of environmental opposition in the new paradigm. While the cases have no apparent close relationships and they occurred in different decades, they offer interesting comparisons. They were basically struggles between water development coalitions and environmental protection coalitions on regional water conflicts. The two proposed projects brought about fierce debates on large dam as they embraced a wide-range of environmental, social, and political issues rather than construction of dams themselves. Huge anti-dam oppositions scrapped them at the cost of nearly ten years for decision-makings and enormous financial resources for feasibility studies respectively. It identifies who the policy actors were, what the policy strategies were, and how the water policies evolved in both countries. The decision-makings on the two projects appeared at first glance to be made under formal institutional frameworks, but in actuality, they relied significantly on decisions of the two important political actors. The Korean society began to learn negotiation and cooperation approaches to solve the water conflict by establishing the Joint Task Force Team on Youngwol project in 1999. The team is recognized as a new conflict resolution method in South Korea because a diverse of stakeholder interests voluntarily participated in the decision-making process and discussed water issues directly. Even though the projects resulted in futile fruits in each country, they illustrate the images of the new paradigm that significantly affected in formulating regional water policies in South Korea and the United States.