• Journal of Institute of Control, Robotics and Systems
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• v.15 no.7
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• pp.683-687
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• 2009

Track jump control is a random access strategy for short distance movement. The most common track jump scheme is a bang-bang control of a kick and brake manner. In a conventional track jump scheme, a track-following compensator is turned off during kick and brake periods, and restarted at a target track for track pull-in. The inevitable controller switching with non-zero initial condition results in undesirable transient response, and excessive overshoot in the transient response causes track pull-in failure. In this paper, a new track jump scheme is proposed for enhancing track jump stability. Instead of control switching, internal states of a track-following controller are artificially manipulated for kick and brake actions in a digital control environment. Experimental results are provided in comparison with conventional track jumps.

• Biomedical Science Letters
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• v.21 no.4
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• pp.241-247
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• 2015

Lactate and ketone bodies are considered biological markers for ketosis and several inherited metabolic disorders. In the current study, the specific ratios of lactate and ketone bodies as analytical tools for differential diagnosis of various lactic acidosis were devised. The study included a protein precipitation step following tert-butyldimethylsilyl derivatisation. Total run time was approximately 30 min including sample preparation and GS/MS analysis. The limits of detection were below 0.1 pg/mL over the targeted 4 analytes. The calibration curve was linear over the concentration range of $0.001{\sim}250{\mu}g/mL$ for pyruvate, beta-hydroxybutyrate, and acetoacetate ($R^2$ > 0.99). Inter-day accuracy and precision were 87.7~94.8% with RSD of 2.5~5.7% at 2 levels. Absolute recoveries (%) of target analytes were 87.0~98.4%. The method was validated for the quantification of lactate and ketone bodies for differentiation of lactic acidosis.

• Bulletin of the Korean Mathematical Society
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• v.29 no.2
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• pp.233-236
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• 1992

Let f:M.rarw.N be a smooth map between Rioemannian manifolds M and N. If f maps geodesics of M to geodesics of N, f is called totally geodesic. As is well known, totally geodesic maps are harmonic and the image f(M) of a totally geodesic map f:M.rarw. N is an immersed totally geodesic submanifold of N (cf. .cint. 6.3 of [W]). We are interested in the following question: When is a harmonic map f:M .rarw. N with rank .leq. 1 everywhere on M totally geodesic\ulcorner In other words, when is the image of a harmonic map f:M .rarw. N with rank .leq. 1 everywhere on M geodesics of N\ulcorner In this note, we give some sufficient conditions on curvatures of M. It is interesting that no curvature assumptions on target manifolds are necessary in Theorems 1 and 2. Some properties of totally geodesic maps are also given in Theorem 3. We think our Theorem 3 is somewhat unusual in view of the following classical theorem of Eells and Sampson (see pp.124 of [ES]).

• Journal of applied mathematics & informatics
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• v.34 no.5_6
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• pp.509-517
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• 2016

In this paper, we consider the following functional equation with involution f(x + y) + f(x + σ(y)) = 2f(x) + f(y) + f(σ(y)) and prove the generalized Hyers-Ulam stability for it when the target space is a non-Archimedean Banach space.

• Proceedings of the KSPS conference
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• 2000.07a
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• pp.211-219
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• 2000

In this paper, we examine fO peak lagging phenomenon in English. FO peak lagging refers to the fact that fO peak corresponding to an accent is realized beyond the domain of the host syllable. We present experimental data of fO peak lagging, which shows that fO peak is heavily delayed when the duration of the accented syllable is relatively short. In addition, we show that fO peak is also heavily delayed and realized in the following syllable in a focused word, even where the target vowel is not intrinsically short.

• Speech Sciences
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• v.8 no.1
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• pp.21-31
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• 2001

The effects of focus on prosodic phrasing, F0, and duration are investigated paying attention not only to the target of focus but also to the constituents that are outside the domain of focus in Korean. We find that the constituents preceding and following the focused word tend to be dephrased. Dephrasing does not always cover up to the Intonation Phrase boundary contrary to Jun's (1993) claim. Dephrasing caused by focus determines F0 and durational difference between focused and neutral sentences. Syntactic constituency is also shown to playa role in prosodic phrasing.

• Journal of the Korean Vacuum Society
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• v.15 no.1
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• pp.103-109
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• 2006

A target for a high-brightness microfocus x-ray tube, which is based on carbon nanotubes (CNT) as electron source, is designed. The x-ray tube has the following specifications: brightness of $1\times10^{11}phs/s.mm^2. mrad^2$, spot size $\~5{\mu}m$, and average x-ray energy of $20\~40 keV$. In order to meet the specifications, the design parameters of the target, such as configuration, material, thickness of the target as well as the required beam current, were optimized using computer code MCNPX. The design parameters were determined from the calculation of both x-ray spectrum and intensity distribution for a transmission type configuration. For the thin transmission type target to withstand vacuum pressure and localized thermal loading, the structural stability and temperature distribution were also considered. The material of the target was selected as molybdenum(Mo) and the optimized thickness was $7.2{\mu}m$ to be backed by $150{\mu}m$ beryllium (Be). In addition, the calculations revealed that the maximum temperature of the transmission target can be maintained within the limits of stable operation.

• Molecules and Cells
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• v.39 no.5
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• pp.395-402
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• 2016

Identifying Hoxc8 target genes is at the crux of understanding the Hoxc8-mediated regulatory networks underlying its roles during development. However, identification of these genes remains difficult due to intrinsic factors of Hoxc8, such as low DNA binding specificity, context-dependent regulation, and unknown cofactors. Therefore, as an alternative, the present study attempted to test whether the roles of Hoxc8 could be inferred by simply analyzing genes frequently coexpressed with Hoxc8, and whether these genes include putative target genes. Using archived gene expression datasets in which Hoxc8 was differentially expressed, we identified a total of 567 genes that were positively coexpressed with Hoxc8 in at least four out of eight datasets. Among these, 23 genes were coexpressed in six datasets. Gene sets associated with extracellular matrix and cell adhesion were most significantly enriched, followed by gene sets for skeletal system development, morphogenesis, cell motility, and transcriptional regulation. In particular, transcriptional regulators, including paralogs of Hoxc8, known Hox co-factors, and transcriptional remodeling factors were enriched. We randomly selected Adam19, Ptpn13, Prkd1, Tgfbi, and Aldh1a3, and validated their coexpression in mouse embryonic tissues and cell lines following $TGF-{\beta}2$ treatment or ectopic Hoxc8 expression. Except for Aldh1a3, all genes showed concordant expression with that of Hoxc8, suggesting that the coexpressed genes might include direct or indirect target genes. Collectively, we suggest that the coexpressed genes provide a resource for constructing Hoxc8-mediated regulatory networks.

• Journal of the Society of Disaster Information
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• v.12 no.1
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• pp.10-18
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• 2016

This study presented a new NOS model through the following suggestions to apply the construction work planing and management to NOS(Network Operating System). First, This study presented CIMS(construction information classification system) reflected the characteristics of facility classification - functional component classification - functional component classification - work classification - resource classification. Based on this system. this study presented how to establish PMMB(performance measurement management baseline) with proposed master target equation which analyzed the trend of performance measurement management baseline and proposed work target equation which analyzed the execution results. Finally, this study presented NOS model that can be applied to fixed price method and cost plus fee method through the theoretical verification of executive performance analysis method.

• Korean Journal of Clinical Pharmacy
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• v.27 no.4
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• pp.276-283
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• 2017

Objective: Dyslipidemia is recognized as a prominent risk factor for cardiovascular and cerebrovascular diseases but it is manageable through therapeutic and lifestyle intervention. Interpreting the latest guidelines is essential for an application of recommendation from guidelines into clinical practice. Therefore, this study aimed to compare the most recent guidelines on dyslipidemia treatment recommendations in Korea and USA. Methods: This study analyzed and compared 2015 Korean guidelines for the management of dyslipidemia, 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline and 2016 supportive guidelines from ACC. Results: A comparison was made focused on the following: target patients based on cardiovascular risk assessment, target goal, and treatment strategies including statin and non-statin therapies. Four target patient groups by risk were suggested in 2015 Korean guideline and cardiovascular risk factors were also considered for initiation of lipid lowering therapy. Titrated statin regimen was recommended by Korean guideline to reach LDL cholesterol and non-HDL cholesterol target level. In 2013 ACC/AHA guideline, four statin benefit group was introduced considering ASCVD risk and high intensity statin or intermediate intensity statin use were recommended without dose titration. 2016 update was to support non-statin therapy based on updated evidence and new consideration of ezetimibe, PCSK9-inhibitor and bile acid sequestrant was brought up. Conclusion: Guidelines are continuously updating as new and important clinical data are constantly released along with the advent of newly approved drugs for lipid disorder. This article provides resources that facilitates uptake of these recommendations into clinical practice.