• 제목/요약/키워드: systematic relationship

검색결과 1,031건 처리시간 0.031초

A systematic review of the biological mechanisms linking physical activity and breast cancer

  • Hong, Bok Sil;Lee, Kang Pa
    • 운동영양학회지
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    • 제24권3호
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    • pp.25-31
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    • 2020
  • [Purpose] Epidemiological evidence has shown that leisure-time physical activity and structured exercise before and after breast cancer diagnosis contribute to reducing the risk of breast cancer recurrence and mortality. Thus, in this review, we aimed to summarize the physical activity-dependent regulation of systemic factors to understand the biological and molecular mechanisms involved in the initiation, progression, and survival of breast cancer. [Methods] We systematically reviewed the studies on 1) the relationship between physical activity and the risk of breast cancer, and 2) various systemic factors induced by physical activity and exercise that are potentially linked to breast cancer outcomes. To perform this literature review, PubMed database was searched using the terms "Physical activity OR exercise" and "breast cancer", until August 5th, 2020; then, we reviewed those articles related to biological mechanisms after examining the resulting search list. [Results] There is strong evidence that physical activity reduces the risk of breast cancer, and the protective effect of physical activity on breast cancer has been achieved by long-term regulation of various circulatory factors, such as sex hormones, metabolic hormones, inflammatory factors, adipokines, and myokines. In addition, physical activity substantially alters wholebody homeostasis by affecting numerous other factors, including plasma metabolites, reactive oxygen species, and microRNAs as well as exosomes and gut microbiota profile, and thereby every cell and organ in the whole body might be ultimately affected by the biological perturbation induced by physical activity and exercise. [Conclusion] The understanding of integrative mechanisms will enhance how physical activity can ultimately influence the risk and prognosis of various cancers, including breast cancer. Furthermore, physical activity could be considered an efficacious non-pharmacological therapy, and the promotion of physical activity is probably an effective strategy in primary cancer prevention.

Clinical effectiveness of different types of bone-anchored maxillary protraction devices for skeletal Class III malocclusion: Systematic review and network meta-analysis

  • Wang, Jiangwei;Yang, Yingying;Wang, Yingxue;Zhang, Lu;Ji, Wei;Hong, Zheng;Zhang, Linkun
    • 대한치과교정학회지
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    • 제52권5호
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    • pp.313-323
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    • 2022
  • Objective: This study aimed to estimate the clinical effects of different types of bone-anchored maxillary protraction devices by using a network meta-analysis. Methods: We searched seven databases for randomized and controlled clinical trials that compared bone-anchored maxillary protraction with tooth-anchored maxillary protraction interventions or untreated groups up to May 2021. After literature selection, data extraction, and quality assessment, we calculated the mean differences, 95% confidence intervals, and surface under the cumulative ranking scores of eleven indicators. Statistical analysis was performed using R statistical software with the GeMTC package based on the Bayesian framework. Results: Six interventions and 667 patients were involved in 18 studies. In comparison with the tooth-anchored groups, the bone-anchored groups showed significantly more increases in Sella-Nasion-Subspinale (°), Subspinale-Nasion-Supramentale(°) and significantly fewer increases in mandibular plane angle and the labial proclination angle of upper incisors. In comparison with the control group, Sella-Nasion-Supramentale(°) decreased without any statistical significance in all treated groups. IMPA (angle of lower incisors and mandibular plane) decreased in groups with facemasks and increased in other groups. Conclusions: Bone-anchored maxillary protraction can promote greater maxillary forward movement and correct the Class III intermaxillary relationship better, in addition to showing less clockwise rotation of mandible and labial proclination of upper incisors. However, strengthening anchorage could not inhibit mandibular growth better and the lingual inclination of lower incisors caused by the treatment is related to the use of a facemask.

노인의 여가 참여동기가 행복감에 미치는 영향: 자기효능감에 대한 매개효과 연구 (A Study on the Impact of the Leisure Motivation of the Elderly upon Happiness: Focusing on the Mediating Effect on Self-Efficacy)

  • 공경배
    • Journal of Platform Technology
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    • 제10권3호
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    • pp.30-43
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    • 2022
  • 본 연구의 목적은 노인의 여가 참여동기, 자기효능감, 행복감 간의 구조적인 역학관계를 확인하여 보다 체계적인 노인의 여가활동 분야의 활성화 방안과 시사점을 제공하는 것이다. 본 연구의 결과는 다음과 같다. 첫째, 노인의 여가 참여동기 중, 유능적 동기를 제외하고 지적 동기, 사회적 동기, 휴식적 동기가 행복감에 유의한 영향을 미치는 것으로 나타났다. 둘째, 노인의 여가 참여동기인 지적, 사회적, 유능적, 휴식적 동기 요인 모두 자기효능감에 긍정적인 영향을 미치는 것으로 나타났다. 셋째, 노인의 자기효능감은 행복감에 유의한 긍정적인 영향을 미치는 것으로 나타났다. 넷째, 노인의 여가 참여동기인 지적, 사회적, 유능적, 휴식적 동기와 행복감의 관계에서 자기효능감은 유의한 매개효과가 있음을 검증하였다.

Strategies to prevent the new infectious diseases from an ecological perspective

  • Lee, Chang Seok
    • Journal of Ecology and Environment
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    • 제46권3호
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    • pp.172-182
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    • 2022
  • Background: The coronavirus problem is an ecological problem stemming from a sudden change in the relationship between parasites and hosts. Ecologists judge organisms that are established out of their original territory as exotic species. Unlike in their original habitat, these exotic species become very aggressive in their newly settled habitat. Coronavirus infection damage was bigger in Europe or the United States than that in the country of its origin, China, and its neighboring countries. Therefore, coronavirus infection damage resembles the damage due to the invasive species. Results: Exotic species are found in places with similar environmental conditions to those of their origin when introduced to other ecological regions. However, there are few ecological ill effects in their place of origin, while the damage is usually severe in the ecological regions in which it is introduced. According to historical records, exotic infectious diseases, such as European smallpox and measles, also showed a similar trend and caused great damage in newly established places. Therefore, it is expected that measures to manage exotic species could be used for the prevention of exotic infectious diseases such as the coronavirus. Conclusions: Prevention comes first in the management of exotic species, and in order to come up with preventive measures, it is important to collect information on the characteristics of related organisms and their preferred environment. In this respect, ecosystem management measures such as exotic species management measures could be used as a reference to prevent and suppress the spread. To put these measures into practice, it is urgently required to establish an international integrated information network for collecting and exchanging information between regions and countries. Furthermore, a systematic ecosystem-management strategy in which natural and human environments could continue sustainable lives in their respective locations may serve as a countermeasure to prevent infectious diseases.

간호대학생의 표준주의 수행에 미치는 영향요인 연구 (A Study on Factors Affecting Nursing Students' Standard Precautions Compliance)

  • 하혜진;김은아
    • 한국융합학회논문지
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    • 제13권5호
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    • pp.473-481
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    • 2022
  • 간호대학생의 표준주의 지식, 표준주의 태도, 사회적 지지 및 표준주의 수행의 관계를 파악하고, 표준주의 수행에 영향을 미치는 요인을 규명하기위해 시도된 서술적 조사연구이다. 연구대상자는 G시에 소재한 3개 대학교 간호대학생 170명을 대상으로 하였다. 자료분석은 SPSS 24.0 프로그램을 이용하였으며 multiple regression로 분석하였다. 연구결과 간호대학생의 표준주의 수행에 영향을 미치는 요인은 사회적 지지, 표준주의 지식 순으로 정적 영향을 미치는 것으로 나타났다. 따라서 간호대학생의 표준주의 수행을 높이기 위해 표준주의 지식의 함량을 증진시키고, 사회적 지지를 긍정적으로 인식하고, 강화시킬 수 있도록 구성된 체계적 교육전략과 프로그램을 개발해야 할 것이다.

실험계획법을 이용한 유연 디스플레이용 무색 투명 폴리이미드 필름의 광학 성능 최적화 (Optimization of Optical Performance of Colorless and Transparent Polyimide Film for Flexible Display using Design of Experiment)

  • 조다운;유연수;남희은;장진해;오충석
    • 반도체디스플레이기술학회지
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    • 제21권1호
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    • pp.79-84
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    • 2022
  • As various flexible display products are released, the demand for high-performance colorless and transparent polyimide (CPI) film is continuously increasing. The primary purpose of this study is to establish a systematic procedure for optimizing the optical performance of CPI films by applying the response surface method. After selecting three key factors (monomer type, stirring time for varnish synthesis, and maximum temperature of vacuum furnace for film production) affecting optical performance based on experiences and references, CPI films were manufactured according to the experimental sequence designed by the central composite design, and then the yellowness index (YI) and optical transmittance (Tr) of the films were measured. When producing a CPI film by pouring varnish into a petri dish, the change in optical properties according to thickness should be considered, and there was a meaningful linear relationship between YI and Tr. The species of monomer and the maximum temperature were the critical factors that had an influence on YI and Tr, respectively. It is expected that the procedure proposed in this study can serve as a starting point for CPI film optimization studies considering the other factors that were not considered and responses such as thermal properties.

공공도서관의 관료제적 특성이 서비스 품질에 미치는 영향 연구 (A Study on the Effects of Bureaucratic Characteristics on Service Quality in Public Libraries)

  • 송현경;김기영
    • 한국문헌정보학회지
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    • 제56권3호
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    • pp.391-414
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    • 2022
  • 본 연구는 공공도서관의 대표적 조직 특성 중 하나를 관료제로 보고, 이것이 서비스 품질을 바탕으로 한 성과에 미치는 영향을 분석하였다. 이를 위해 한국의 수도권에 위치한 8개 공공도서관의 이용자를 대상으로 설문조사를 실시하여 각 도서관의 서비스 품질을 조사하였고 사서를 통해 각 도서관의 관료제 특성을 조사하였다. 이를 바탕으로 관료제 특성이 서비스 품질에 미치는 영향을 분석하였다. 분석 결과, 관료제 및 탈관료제 특성들은 모두 서비스 품질에 영향을 미치는 인과 관계가 있는 것으로 나타났다. 특히, 관료제 특성들의 조합은 서비스 품질에 영향을 미치는 것으로 분석되었다. 이와 함께 관료제 특성 중 규칙 체계는 서비스 품질에 중요한 영향을 미치는 것으로 나타났다. 본 연구는 공공도서관 조직이 양질의 서비스를 생산하는 데 필요한 관료제 특성을 실증 연구를 통하여 제시하였다는 데 의의가 있다.

Ectopic teeth with disparate migration: A literature review and new case series

  • Pallak Arora ;Madhu K. Nair ;Hui Liang ;Paras B. Patel ;John M. Wright;Mehrnaz Tahmasbi-Arashlow
    • Imaging Science in Dentistry
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    • 제53권3호
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    • pp.229-238
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    • 2023
  • Purpose: Ectopic eruption can be defined as the emergence of a tooth in an abnormal location, where the tooth does not follow its typical eruption pathway. While ectopic eruption within the dentate region is well-documented in the literature, ectopic eruption in non-dentate regions is relatively rare. This study aimed to report 6 cases of ectopic teeth and present a systematic review of the English-language literature on ectopic teeth, emphasizing demographic characteristics, radiographic features, potential complications, and treatment options. Materials and Methods: A literature search was conducted using the PubMed, Medline, Web of Science, and Cochrane databases. The demographic data and radiographic findings of patients presenting with ectopic teeth were recorded. Results: The literature review yielded 61 cases of ectopic teeth, with patients ranging in age from 3 to 74 years. The findings from these previously reported cases demonstrated that the most common location for ectopic teeth was the maxillary sinus, which is consistent with this case series. The Pearson chi-square test was performed to evaluate the correlation between age and location of ectopic teeth, and the results were found to be statistically significant (P<0.05). However, no statistically significant relationship was observed between sex and the location of ectopic teeth. Conclusion: The distinct features of these cases warrant reporting. This study presents the first case of supernumerary teeth in the condyle without any associated pathosis. Another notable characteristic is the pre-eruptive resorption of 2 inverted supernumerary teeth ectopically located in the palate, which predisposes to sinus opacification.

Factors Clustering Approach to Parametric Cost Estimates And OLAP Driver

  • JaeHo, Cho;BoSik, Son;JaeYoul, Chun
    • 국제학술발표논문집
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    • The 3th International Conference on Construction Engineering and Project Management
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    • pp.707-716
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    • 2009
  • The role of cost modeller is to facilitate the design process by systematic application of cost factors so as to maintain a sensible and economic relationship between cost, quantity, utility and appearance which thus helps in achieving the client's requirements within an agreed budget. There are a number of research on cost estimates in the early design stage based on the improvement of accuracy or impact factors. It is common knowledge that cost estimates are undertaken progressively throughout the design stage and make use of the information that is available at each phase, through the related research up to now. In addition, Cost estimates in the early design stage shall analyze the information under the various kinds of precondition before reaching the more developed design because a design can be modified and changed in all process depending on clients' requirements. Parametric cost estimating models have been adopted to support decision making in a changeable environment, in the early design stage. These models are using a similar instance or a pattern of historical case to be constituted in project information, geographic design features, relevant data to quantity or cost, etc. OLAP technique analyzes a subject data by multi-dimensional points of view; it supports query, analysis, comparison of required information by diverse queries. OLAP's data structure matches well with multiview-analysis framework. Accordingly, this study implements multi-dimensional information system for case based quantity data related to design information that is utilizing OLAP's technology, and then analyzes impact factors of quantity by the design criteria or parameter of the same meaning. On the basis of given factors examined above, this study will generate the rules on quantity measure and produce resemblance class using clustering of data mining. These sorts of knowledge-base consist of a set of classified data as group patterns, of which will be appropriate stand on the parametric cost estimating method.

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초국가적 동아시아정체성에 대한 연령 및 세대코호트, 국가정체성의 효과분석 (Analysing the Effects of Age, Generational Cohorts, National Identity on Supranational Regional Identity)

  • 지은주;권혁용
    • 국제지역연구
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    • 제14권1호
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    • pp.309-330
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    • 2010
  • 이 논문은 동아시아정체성에 영향을 미치는 연령 및 세대코호트(cohort)효과에 대해 분석한다. 또한 이 논문은 동아시아 지역정체성이 한국인이라는 국가정체성(national identity)의 정도와 어떠한 방식으로 연관되는가를 분석한다. 2008년 시카고국제문제협의회-동아시아연구원에서 실시한 한국인 여론조사 데이터에 대한 분석은 다음과 같은 흥미로운 경험적 발견을 제시한다. 연령이 높을수록 동아시아정체성의 정도가 더 강하게 나타나며, 국가정체성이 강할수록 강한 동아시아정체성을 지니는 경향이 있다. 이러한 경험적 발견은 서구를 대상으로 한 기존연구들의 발견과는 다른 패턴을 보이는 것이다. 첫째, 한국의 경우 젊은 층이 아니라 경제적 자원이 어느 정도 있는 연령층이 더 초국가정체성을 지닌다. 둘째, 일반적인 동북아공동체에 관한 연구의 논의와 다르게, 이 연구는 강한 국가정체성이 동아시아 지역정체성과 상보적(complementary)이라는 점을 제시한다. 이 연구는 동아시아지역통합의 이론적, 정책적 모색과 동아시아 지역 내 강한 민족주의의 관계에 대한 새로운 미시적 기초를 밝혀준다.