• Journal of applied mathematics & informatics
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• v.32 no.5_6
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• pp.737-746
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• 2014

Treatment method refers to a principle or method for treating diseases in Traditional Korean Medicine(TKM). As doctors determine the ideal treatment for a patient's disease or symptom, they are also able to prescribe effective treatment means for the diseases or symptom such as medicinal materials, prescription, acupuncture and moxibustion. Therefore, if significant symptom-treatment method combinations are found from literature or database, proper treatment means for the patient's diseases or symptom may be presented to TKM doctors and enhanced treatment accuracy and efficiency can be expected. This study aims to analyze the relation between symptom and treatment method by interpreting hypotheses through null hypotheses to find significant symptom-treatment method combinations. This combinations suggested in this study will be compared with TKM experts analysis result to find an objective analysis method and eventually apply the method to medical big data, e.g., a huge amount of literature or treatment records.

• The Korean Journal of Mycology
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• v.12 no.4
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• pp.171-174
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• 1984

To investigate the relationship between symptom development of Bakanae disease and yield component (the length of panicle, weight of panicle, number of healthy grain per panicle and number of panicle per hill), rice seedlings infected with F. moniliforme were transplanted. The number of panicles per hill and healthy grain per panicle were greatly decreased by the development of Bakanae symptom. Yield components was not correlated with the time of the Bakanae symptom development. Rice plants with Bakanae symptom had lower yield as 210g per 10 hills than healthy plants as 469g per 10 hills.

• Korean Journal of Adult Nursing
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• v.17 no.2
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• pp.208-218
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• 2005

This study was conducted to develop and evaluate guidelines for cancer patients' symptoms management such as nausea/vomiting, fatigue, constipation, diarrhea, and oral mucositis. Based on the literature review, assessment path to identify each stage of five symptoms were also developed. Guidelines for symptom management of each stage of the symptoms were developed. Guidelines then were evaluated by a panel of experts. Finally, 95 cancer patients were recruited and asked to use the guidelines for their symptom management. Levels of understanding of and satisfaction with assessment path and management guidelines were surveyed. Prevalence rate of five symptoms varied ranging from 20% (diarrhea) to 47% (nausea/vomiting). Regarding the level of understanding of each symptom most of the cancer patients indicated that they were easy and sufficient. Regarding the easiness of use of the symptom management guidelines, most of cancer patients indicated that they were easy to use. Regarding the nursing intervention on each symptom, most of cancer patients indicated that they were easy and helpful. More information was added with feedback from the patients. The result of this study has implications on development of customized patient education materials based on assessment path and symptom management guidelines.

• International Journal of Industrial Entomology and Biomaterials
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• v.39 no.2
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• pp.45-53
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• 2019

The popularity of keeping stag beetles (Dorcus titanus castanicolor Motschulsky 1861, Coleoptera: Lucanidae) as pets has increased. Consistent with the rise in the number of insect farms using these beetles, the number of contaminated or diseased D. titanus castanicolor has also increased. This investigation was conducted to analyze the cause of D. titanus castanicolor disease. The contaminated larvae of D. titanus castanicolor showed Allomyrina nudivirus infection symptoms similar to those of Allomyrina nudivirus infection. However, the disease carried by of D. titanus castanicolor is not derived from the virus infecting Allomyrina, as determined by PCR. Our study revealed that the major gut microbes of infectious D. titanus castanicolor belonged to the phylum Proteobacteria, and specifically, Pseudomonas knackmussi (Symptom 1 - 39.62% to Symptom 2 - 41.50% to Symptom 3 - 76.76% as the disease progressed severely) and Citrobacter koseri (Symptom 1 - 1.48% to Symptom 2 - 6.04% to Symptom 3 - 6.16% as the disease progressed severely) were detected. Additionally, a high proportion of larvae from the uninfected group were found to harbor bacteria belonging to the phylum Firmicutes (72%). However, as the disease progressed severely in these beetles, the proportion of Firmicutes decreased (Symptom 1 - 72.03% to Symptom 2 - 44.7% to Symptom 3 - 26.3%). These findings imply that colonization by Firmicutes was inversely proportional to Proteobacteria colonization in the gut. This was found to be true for both the normal and disease conditions of D. titanus castanicolor. In this study, we examined the distribution of intestinal microbial communities in normal and contaminated larvae. We observed a correlation between these contaminated microbes and the overall health of the beetle, and our findings suggest that there may be a link between disease progression and the gut microbiome.

• Women's Health Nursing
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• v.24 no.3
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• pp.297-309
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• 2018

Purpose: To develop Pregnancy Risk symptom Perception Scale (PRPS) and evaluate its validity and reliability. Methods: A preliminary 30-item version of PRPS was developed through literature review, in-depth interview, and Content Validity. Each item was scored on a four-point Likert scale. The preliminary scale was developed based on 301 pregnant women who visited a hospital. Date were analyzed using item analysis, factor analysis, confirmatory factor analysis, Pearson's correlation coefficients, and Cronbach's ${\alpha}$ (0.90 for total item, 0.80 to 0.88 for factors). Results: The PRPS consisted of 27 items. Three factors (physical, environmental, and emotional factors) explained 55% of the total variance. Cronbach's Criterion validity was supported by comparison with the Perception of Pregnancy Risk Questionnaire (r=0.34). In reliability test, the reliability coefficient of pregnancy risk symptom perception was high at 0.90. Conclusion: These results suggest that the pregnancy risk symptom perception scale developed in this study comprises items that can assess the level of pregnant women's pregnancy risk symptom perception in Korea. Its validity and reliability were proven. PRPS can be utilized to measure pregnant women's risk symptom perception during pregnancy. PRPS will contribute to the development of systematic prenatal care and effective risk management.

• The Plant Pathology Journal
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• v.30 no.3
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• pp.316-322
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• 2014

Recently, a Cucumber mosaic virus (CMV) strain, named as CMV-209, was isolated from Glycine soja. In this study, symptom expression of CMV-209 was analyzed in detail in Nicotiana benthamiana by comparing with that of CMV-Fny, which is a representative strain of CMV. Using infectious cDNA clones of CMV strains 209 and Fny, symptom expression of various pseudorecombinants between these two strains were examined in the early and late infection stages. In the early infection stage, the pseudorecombinants containing Fny-RNA2 induced stunting and leaf distortion on the newly emerged leaves whereas the pseudorecombinants containing 209-RNA2 caused no obvious symptoms. In the late infection stage, the pseudorecombinants containing 209-RNA1 and Fny-RNA2 induced severe leaf distortion and stunting, while CMV-209 induced mild symptom and CMV-Fny caused typical mosaic, general stunting, and leaf distortion symptoms, indicating that RNA 2 encodes a symptom determinant(s) of CMV, which is capable of enhancing symptoms. Furthermore, our results support the possibility that natural recombination between compatible viruses can result in emergence of novel viruses causing severe damages in crop fields.

• Horticultural Science & Technology
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• v.28 no.4
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• pp.529-534
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• 2010

Occurrence of wilted symptom in watermelon plant ($Citrullus$ $lanatus$ L.) is known to be caused by physiological disorder. The symptom results in the loss of fruit production and thus the economical loss of watermelon growers. The incidence of symptom is often found from the middle of March to the end of May in the major watermelon crop production areas of Korea (i.e. Uiryeong, Gyeongnam (lat $37^{\circ}$56'64"N, long $126^{\circ}$99'97"E)). Despite of extensive information about the physiological disorder, little study has been conducted to understand a relationship between the wilted symptom and accompanying environment factors (e.g. temperature). This study aimed to investigate effects of environmental conditions amended by a forced-ventilation system on physiological characteristics of watermelon and incidence of the wilted symptom. Watermelon plants were grown from January to May, 2009 with either the forced-or natural-ventilation treatment in a greenhouse located in the Uiryeong. In the result, the forced-ventilation treatment decreased the air, leaf and root-zone temperature approximately $4.5^{\circ}C$, $5^{\circ}C$ and $3^{\circ}C$, respectively, compared to the natural-ventilation. The fruit growth rate was maximized twice during the entire growing period. The higher rate of fruit growth was observed under the natural-ventilation than the forced one. Maximization of the fruit growth rate (approximately 430 g per day) was first observed by 12 days after fruiting under the natural-ventilation treatment, while the second one (approximately 350 g per day) was observed by 24 days after fruiting. The wilted symptom started occurring by 22 days after fruiting under the natural-ventilation, whereas no incidence of the symptom was found under the forced-ventilation treatment. Interestingly, the forced-ventilation lowered the fruit growth rate (approximately 320 g per day) compared to the natural one. Maximization of the fruit growth rate under the forced-ventilation was found at 4 days later than that under the natural one. This result coincided with a slower plant growth under the forced-ventilation treatment. These results suggest that the forced-ventilation slows down extension growth of fruit and plant, which may be associated with lowering leaf temperature and saturation deficit. We suggest the hypothesis that the forced-ventilation may alleviate stress of the wilted symptom by avoiding extreme water evaporation from leaves due to high temperature and thus by reducing competition between leaves and fruits for water. More direct and detailed investigations are needed to confirm the effect of the forced ventilation.

• Journal of Plant Biology
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• v.39 no.4
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• pp.249-256
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• 1996

Beet curly top virus is the DNA virus that is providing useful for basic studies of the infection of Arabidopsis thaliana with viral host and provides a system for studying both resistance and the molecular basis of symptom development. An importnat aspect of symptom development observed in BCTV-infected A. thaliana (ecotype Sei-O) was the induction of cell division on phloem and surrounding cortex cells. Analysis of the expression of GUS reporter gene activity in transgenic plants containing constructs with promoter of the auxin-inducible saur gene showed that saur promoter activity was induced concomitantly in symptomatic tissues at the inflorescence shoot tips of the transgenic lines. The auxin sensitivity tests showed that hypersusceptible ecotype, Sei-O produced more amounts of callus than susceptible ecotype, Col-O. These studies indicated that changes in auxin concentration were involved in the induction of cell division in BCTV-infected plants and clearly demonstrated that there was a strong correlation between auxin-induced gene expression and the activation of cell division.

• Korean Journal of Occupational Health Nursing
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• v.26 no.1
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• pp.30-39
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• 2017

Purpose: The aim of this study was to explore the association between psychosocial work environments and depressive symptoms among Korean registered nurses. Methods: The study population of 331 registered nurses was derived from the 2014 Korean Working Condition Survey (KWCS). Depressive symptom was assessed using the WHO-5 wellbeing index. Results: The thirty-five percentage of Korean registered nurses reported the risk for depressive symptom. Korean nurses with higher 'work-family conflict' were more likely at the risk of depression almost 1.83 (95% CI 1.04~3.20) times than their counterpart. Higher 'possibilities for development' were more likely decrease almost 60% of the risk of depressive symptom. Conclusion: Work-family conflict and possibility of development were associated with depressive symptom among Korean registered nurses. We suggest future researches identifying strategies for decreasing work-family conflict and its negative effects.

• Journal of Sasang Constitutional Medicine
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• v.32 no.4
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• pp.45-64
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• 2020

Purpose This study was to develop and study 'Diagnostic Index for the Ordinary Symptom of Soyangin'. Methods The main diagnosis and evaluation index symptoms of Soyangin were extracted based on 『Donguisusebowon』 and Clinical Practice Guidelines for Sasang Constitutional Medicine Symptomatology; CPG for soyangin. The selected ordinary symptoms were divided into 4 categories such as Exterior-Cold ordinary symptom (表寒素證), Exterior-Disease unfavorable's ordinary symptom (表病逆證素證), Interior-Heat ordinary symptom (裏熱素證), Interior-Disease unfavorable's ordinary symptom (裏病逆證素證) of Soyangin and translated into Korean. And the inclusion, importance and translation validity of major diagnosis and assessment indicators of Soyangin were surveyed online by a group of Sasang constitutional experts. Results & Conclusions 29 ordinary symptoms and pathological mechanism were selected from references and translated into 51 Korean symptoms. After inclusion yes or no survey by expert group, 45 symptoms were selected. The importance survey showed that 'Have a soft stool' of Exterior-Cold ordinary symptom indication, '(If you're stressed, if you're not in good health) Have a soft stool or diarrhea' of Exterior-Disease unfavorable's ordinary symptom, 'The feces harden easily' of Interior-Heat ordinary symptom and '(If you're stressed, if you're not in good health) Have an upset stomach' of Interior-Disease unfavorable's ordinary symptom were the most important. Finally, [Diagnostic Index for the Ordinary Symptom of Soyangin] was completed after survey of translation validity, reflection of individual opinions by the expert committee, and application of weighted value calculated from the importance survey.