• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XII)
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• pp.263-266
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• 2003

감미제로 많이 사용되고 있는 약용식물 중 대추와 감초, 황기로부터 기능성 천연 감미료를 얻기 위해 에탄올과 물을 추출용매로 사용하여 당류가 포함된 시료를 얻었다. 이들 시료에 대한 감미효과를 구체적으로 알아보기 위해 당 분석 및 난충치성 실험을 실시한 결과 황기와 감초에서 산생성력과 dental plaque의 수치가 낮게 나타나 기능성 천연 감미료를 얻을 수 있는 약용식물로 판단된다.

• 센서학회지
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• 제27권3호
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• pp.156-159
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• 2018

We developed a glucose sensor using glucose dehydrogenase flavin adenine dinucleotide (GDH-FAD). The structure of the three-layer glucose sensor was simplified, in which a single-layer design was used to lower the unit cost, and GDH-FAD was used to increase the measurement reliability. GDH-FAD has less impact on the 20 interfering substances that affect blood glucose measurement, such as galactose and maltose compared to glucose oxidase (GOD), and is not affected by the oxygen saturation; therefore, it is possible to measure both arterial or venous blood and thus less susceptibility to hematocrit. In this study, we developed a single-layer glucose sensor strip with low hematocrit effect using the GDH-FAD enzyme, and measured and evaluated the performance.

• Communications for Statistical Applications and Methods
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• 제27권1호
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• pp.37-46
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• 2020

Recurrent event data frequently occur in clinical studies, demography, engineering reliability and so on (Cook and Lawless, The Statistical Analysis of Recurrent Events, Springer, 2007). Sometimes, two or more different but related type of recurrent events may occur simultaneously. In this study, our interest is to estimate the covariate effect on bivariate recurrent event times with zero inflations. Such zero inflation can be related with susceptibility. In the context of bivariate recurrent event data, furthermore, such susceptibilities may be different according to the type of event. We propose a joint model including both two intensity functions and two cure rate functions. Bivariate frailty effects are adopted to model the correlation between recurrent events. Parameter estimates are obtained by maximizing the likelihood derived under a piecewise constant hazard assumption. According to simulation results, the proposed method brings unbiased estimates while the model ignoring cure rate models gives underestimated covariate effects and overestimated variance estimates. We apply the proposed method to a set of bivariate recurrent infection data in a study of child patients with leukemia.

• Mycobiology
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• 제48권1호
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• pp.1-8
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• 2020

Pentraxin 3 (PTX3) is a soluble pattern recognition receptor (PRR), which is produced by several kinds of cells, such as neutrophils, dendritic cells, macrophages, and epithelial cells. PTX3 is known to play an important protective effect against Aspergillus. Genetic linkage in gene-targeted mice and human PTX3 plays a non-redundant role in the immune protection against specific pathogens, especially Aspergillus. Recent studies have shown that the polymorphism of PTX3 is associated with increased susceptibility to invasive aspergillosis (IA). In this review, we provide an overview of these studies that underline the potential of PTX3 in diagnosis and therapy of IA.

• 미생물학회지
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• 제30권3호
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• pp.177-180
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• 1992

Among 120 U. maydis strains isolated in Korea 14 different strains containing specific viral dsRNA segments were analyzed for the distribution of dsRNA and the production of toxin protein. Several distinctive dsRNA patterns were identified, 9 cases of P type with typical H, M and L ds RNA and one case of non-P-type, the frequency of a specific isolate was decreased with increasing number of dsRNA segments. The presence of dsRNA had no effect on the cultural or morphological phenotype of the host. Two isolates containing P type dsRNA segments appeared to produce toxin protein (killer strains) which inhibited the growth of 4 isolates (sensitive strain) with different susceptibility. Two killer strains contain unique M dsRNA segment which may code for toxin protein. However, the presence of toxin-sensitive strains among dsRNA-free isolates was similar to that of ds RNA containing strains.

• 터널과지하공간
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• 제6권2호
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• pp.166-174
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• 1996

Stability of rock slope is greatly affected by the geometry and strength of discontinuities developed in the rock mass. In this study an analytical method which is capable of analyzing the effect of relative orientation between the discontinuities and the slope face on the safety of slope by assessing their vector components was used to evaluate the stability and the maximum cut-angle for the proposed slope design. The results of computerized vector analysis revealed that slope area under investigation might be divided into 3 sections of different face directions. The safety factors for benches in each 3 sections were calculated using the limit-equilibrium theory. Then, by utilizing the concept of probabilistic risk analysis, the susceptibility of entire slope failure was estimated. Based on the distribution of safety factor in each bench, the maximum cut angle of each section could be selected differently ot achieve the permanent stability of the entire slope.

• The Korean Journal of Pain
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• 제18권2호
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• pp.208-209
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• 2005

Interstitial cystitis is an extremely painful and distressing condition, characterized by severe suprapubic pain, which increases with bladder filling and is relieved by voiding. The daily frequency of micturition may approach 100 times, but no incontinence is observed. The symptoms persist throughout the night, which consequently affects sleep. The etiology of this condition is still unknown, but includes infection, autoimmune response, allergic reaction, neurogenic inflammation, epithelial dysfunction and inherited susceptibility. Herein, a case of interstitial cystitis, with severe symptoms, which was successfully treated with lumbar sympathetic block, is reported.

• 한국군사과학기술학회지
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• 제11권6호
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• pp.148-155
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• 2008

We investigated the damage effects of microcontroller devices under high power electromagnetic(HPEM) wave. HPEM wave was radiated from the open-ended standard rectangular waveguide(WR-340) to free space. The influence of different reset-, clock-, data-, and power supply-line lengths has been tested. The susceptibility of the tested microcontroller devices was in general much influenced by clock-, reset-, and power supply-line length, little influenced by data-line length. Further the line length was increased, the malfunction threshold was decreased as expected, because more energy couples to the devices. The surfaces of the destroyed microcontroller devices were removed and the chip conditions were investigated with microscope. The microscopic analysis of the damaged devices showed component and bondwire destructions such as breakthroughs and melting due to thermal effects.

• 한국환경교육학회지:환경교육
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• 제23권3호
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• pp.97-114
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• 2010

The aims of this study are to develop and apply a Nature Game program for the ecological experience learning in Jeju Gotjawal forest and analyze the environmental sensitivity change of the students. The results obtained in 4th graders of A elementary school of Seogwipo-city are as follows: It was found that attention, susceptibility and practice will of environment protection for forest environment of the experimental class were significantly higher than those of the comparison class. And it was found that interest and curiosity into forest environment were also elevated in the results of the qualitative evaluation, suggesting that we could get the effect of developed Nature Game program on ecological experience learning. If various ecological experience learning programs considering the regional-specific characteristics are developed to cause students' interest and curiosity, students would come to participate in the protection activity of environment aggressively a little more.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.211-216
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• 2002

To investigate transition region in welded overlay relating to disbonding crack, the effect of vanadium addition on disbonding of Cr-Mo steels overlay welded with austenitic stainless steel was studied. V modified Cr-Mo steels have a higher resistance to disbonding than V free Cr-Mo steel. One reason is due to the fact that fine vanadium carbide precipated in base metal traps hydrogen and thus decreases the susceptibility to the disbonding. The second is related to the higher stability of the vanadium and stable carbides formed during PWHT, in which the carbon diffusion to the interface is lower than for V free Cr-Mo steel. Decreasing the carbon content at the interface of the weld overlay shows good resistance to the disbonding. Hence, it is important to control the carbon content at the interface of the weld overlay.