• Title/Summary/Keyword: susceptibility assessment

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Assessment of Bacterial Contamination of Bottled Water in Korea, 2005 (2005년 한국에서 시판된 먹는 샘물의 미생물 오염)

  • Kim Yun-A;Lee Do-Kyung;Yu Kyoung-Mi;Kang Byung-Yong;Ha Nam-Joo
    • Environmental Analysis Health and Toxicology
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    • v.21 no.3 s.54
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    • pp.283-289
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    • 2006
  • In recent years, there has been an increase in consumer demand for bottled waters. There is a perception that consumption of natural mineral water represents a healthy life style and that these products are relatively safe. In this study, the microbiological quality of 39 samples of bottled water, purchased from retail store in Korea, was investigated during the 2005. Applying pour plate method, the 1 mL of water samples were analyzed for the presence and enumeration of total general bacteria and Pseudomonas spp.. Nineteen samples representing 9 brands of bottled water contained general bacteria ($1.54{\times}10^2$ CFU/mL). In addition four samples contained Pseudomonas spp. and Camamonas acidovorans. The susceptibility of the strains tested against 25 antimicrobial agents, Pseudomonas fluorescens were resistant to Lincomycin, Amoxacilin/Clavulanic acid and Cefazolin (> $100{\mu}g/mL$). Also Comamonas acidovorans were intermediate to Cephalothin and resistant to Cefoperazone.

The analysis of E-field produced by satellite S-band under fairing of launcher (인공위성 S-band가 형성한 발사체 패어링내의 전기장 해석)

  • Kim, Eui-Chan;Lee, Sang-Kon
    • Aerospace Engineering and Technology
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    • v.10 no.2
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    • pp.82-86
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    • 2011
  • This paper presents an RF Electric field assessment at 2.290 [GHz] inside launcher PROTON M/Breeze M long fairings, produced by COMS TM. COMS intentional RE due to TM ON under fairing has been assessed considering PROTON M / BREEZE M fairing characteristics. As fairings of all launchers present similar sizes, a similar E-field level under fairing is expected for the other launchers. As a result, the RE level under faring is compliant with COMS RS limits, but is not compliant with RS requirements of the launcher PROTON M/Breeze M.

Quantitative Evaluation of the Impact of Low-Voltage Loads due to Repetitive Voltage Sags

  • Yun Sang-Yun;Kim Jae-Chul;Moon Jong-Fil;Kang Bong-Seok
    • KIEE International Transactions on Power Engineering
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    • v.5A no.3
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    • pp.293-299
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    • 2005
  • Automatic reclosing is a typical protection method in power distribution systems for the clearing of temporary faults. However, it has a fatal weakness in regards to voltage sags because it produces repetitive voltage sags. In this paper, we explored the repetitive impact of voltage sag due to the automatic reclosing of power distribution systems. The actual tests of low voltage loads were carried out for obtaining the susceptibility of voltage sags. The final results of the tests yielded power acceptability curves of voltage sag, and the curves transformed the 3-dimensional CBEMA (Computer Business Equipment Manufacturer Association) format. For the quantitative evaluation of the impact of repetitive voltage sags, an assessment formulation using the voltage sag contour was proposed. The proposed formulation was tested by using the voltage sag contour data of IEEE standard and the results of the test. Through the case studies, we verified that the proposed method can be effectively used to evaluate the actual impact of repetitive voltage sags.

Experimental assessment of the effect of frozen fringe thickness on frost heave

  • Jin, Hyun Woo;Lee, Jangguen;Ryu, Byun Hyun;Shin, Yunsup;Jang, Young-Eun
    • Geomechanics and Engineering
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    • v.19 no.2
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    • pp.193-199
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    • 2019
  • A frozen fringe plays a key role in frost heave development in soils. Previous studies have focused on the physical and mechanical properties of the frozen fringe, such as overall hydraulic conductivity, water content and pore pressure. It has been proposed that the thickness of the frozen fringe controls frost heave behavior, but this effect has not been thoroughly evaluated. This study used a temperature-controllable cell to investigate the impact of frozen fringe thickness on the characteristics of frost heave. A series of laboratory tests was performed with various temperature boundary conditions and specimen heights, revealing that: (1) the amount and rate of development of frost heave are dependent on the frozen fringe thickness; (2) the thicker the frozen fringe, the thinner the resulting ice lens; and (3) care must be taken when using the frost heave ratio to characterize frost heave and evaluate frost susceptibility because the frost heave ratio is not a normalized factor but a specimen height-dependent factor.

Clinical impact of cerebral microbleeds on cognition in patients with CADASIL

  • Lee, Jung Seok;Ko, Keun Hyuk;Oh, Jung-Hwan;Choi, Jay Chol;Kim, Joong-Goo
    • Journal of Medicine and Life Science
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    • v.15 no.2
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    • pp.89-94
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    • 2018
  • Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is inherited microangiopathy caused by mutations in the Notch3 gene. Typical findings from brain magnetic resonance imaging (MRI) include subcortical lacunes, extensive white matter change and cerebral microbleeds(CMBs). CMBs are indicative of bleeding-prone microangiopathy. Despite some studies investigating the association between lacunes and cognitive dysfunction in CADASIL, few studies have examined the relationship between cognitive dysfunction and CMBs. We sought to assess whether CMBs are associated with cognitive dysfunction in CADASIL. This study enrolled 83 consecutive patients with CADASIL between April 2012 and January 2014. Their degree of cognitive dysfunction was assessed by the Korean version of the CERAD neuropsychological assessment battery, digit span test, and the Stroop test. A 3.0-T MRI was used to obtain T1-weighted, fluid-attenuated inversion recovery, and susceptibility weighted images. In multiple logistic regression analysis, the grade of CMBs influenced tests of memory dysfunction (p=0.003). Three or more lacunes correlated with dysfunction in the executive domain (p=0.013) and attention domain (p=0.005). White matter hyperintensity (WMH) was an independent predictor of executive dysfunction (p=0.001). These findings suggest that in addition to lacunes, CMBs and WMHs may be useful imaging markers to associated with cognitive dysfunction in CADASIL.

Difference of Potential Range Formed at the Anode Between Water Drop Test and Temperature Humidity Bias Test to Evaluate Electrochemical Migration of Solders for Printed Circuit Board

  • Young Ran Yoo;Young Sik Kim
    • Corrosion Science and Technology
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    • v.22 no.3
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    • pp.153-163
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    • 2023
  • Two types of accelerated tests, Water Drop Test (WDT) and Temperature-Humidity-Bias Test (THBT), can be used to evaluate the susceptibility to electrochemical migration (ECM). In the WDT, liquid water is directly applied to a specimen, typically a patterned conductor like a printed circuit board. Time to failure in the WDT typically ranges from several seconds to several minutes. On the other hand, the THBT is conducted under elevated temperature and humidity conditions, allowing for assessment of design and life cycle factors on ECM. THBT is widely recognized as a more suitable method for reliability testing than WDT. In both test methods, localized corrosion can be observed on the anode. Composition of dendrites formed during the WDT is similar to that formed during THBT. However, there is a lack of correlation between the time to failure obtained from WDT and that obtained from THBT. In this study, we investigated the relationship between electrochemical parameters and time to failure obtained from both WDT and THBT. Differences in time to failure can be attributed to actual anode potential obtained in the two tests.

Prediction of Landslides and Determination of Its Variable Importance Using AutoML (AutoML을 이용한 산사태 예측 및 변수 중요도 산정)

  • Nam, KoungHoon;Kim, Man-Il;Kwon, Oil;Wang, Fawu;Jeong, Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.30 no.3
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    • pp.315-325
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    • 2020
  • This study was performed to develop a model to predict landslides and determine the variable importance of landslides susceptibility factors based on the probabilistic prediction of landslides occurring on slopes along the road. Field survey data of 30,615 slopes from 2007 to 2020 in Korea were analyzed to develop a landslide prediction model. Of the total 131 variable factors, 17 topographic factors and 114 geological factors (including 89 bedrocks) were used to predict landslides. Automated machine learning (AutoML) was used to classify landslides and non-landslides. The verification results revealed that the best model, an extremely randomized tree (XRT) with excellent predictive performance, yielded 83.977% of prediction rates on test data. As a result of the analysis to determine the variable importance of the landslide susceptibility factors, it was composed of 10 topographic factors and 9 geological factors, which was presented as a percentage for each factor. This model was evaluated probabilistically and quantitatively for the likelihood of landslide occurrence by deriving the ranking of variable importance using only on-site survey data. It is considered that this model can provide a reliable basis for slope safety assessment through field surveys to decision-makers in the future.

Improvement of Fat Suppression and Artifact Reduction Using IDEAL Technique in Head and Neck MRI at 3T

  • Hong, Jin Ho;Lee, Ha Young;Kang, Young Hye;Lim, Myung Kwan;Kim, Yeo Ju;Cho, Soon Gu;Kim, Mi Young
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.1
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    • pp.44-52
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    • 2016
  • Purpose: To quantitatively and qualitatively compare fat-suppressed MRI quality using iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) with that using frequency selective fat-suppression (FSFS) T2- and postcontrast T1-weighted fast spin-echo images of the head and neck at 3T. Materials and Methods: The study was approved by our Institutional Review Board. Prospective MR image analysis was performed in 36 individuals at a single-center. Axial fat suppressed T2- and postcontrast T1-weighted images with IDEAL and FSFS were compared. Visual assessment was performed by two independent readers with respect to; 1) metallic artifacts around oral cavity, 2) susceptibility artifacts around upper airway, paranasal sinus, and head-neck junction, 3) homogeneity of fat suppression, 4) image sharpness, 5) tissue contrast of pathologies and lymph nodes. The signal-to-noise ratios (SNR) for each image sequence were assessed. Results: Both IDEAL fat suppressed T2- and T1-weighted images significantly reduced artifacts around airway, paranasal sinus, and head-neck junction, and significantly improved homogeneous fat suppression in compared to those using FSFS (P < 0.05 for all). IDEAL significantly decreased artifacts around oral cavity on T2-weighted images (P < 0.05, respectively) and improved sharpness, lesion-to-tissue, and lymph node-to-tissue contrast on T1-weighted images (P < 0.05 for all). The mean SNRs were significantly improved on both T1- and T2-weighted IDEAL images (P < 0.05 for all). Conclusion: IDEAL technique improves image quality in the head and neck by reducing artifacts with homogeneous fat suppression, while maintaining a high SNR.

Assessment of Earthquake Induced Landslide Susceptibility with Variation of Groundwater Level (지하수위 변화에 따른 지진 유발 산사태의 취약섬 분석)

  • Kim, Ji-Seok;Park, Hyuek-Jin;Lee, Jung-Hyun
    • Economic and Environmental Geology
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    • v.44 no.4
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    • pp.289-302
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    • 2011
  • Since the frequency of the earthquake occurrence in Korean peninsular is continuously increasing, the possibility that massive landslides are triggered by earthquake is also growing in Korea. Previously, the landslide is known to be induced by large magnitude earthquake, whose magnitude is larger than 6.0. However, the landslide can be induced by only small magnitude earthquake, especially in the fully saturated soil. Therefore, the susceptibility of landslide caused by small magnitude earthquake in fully saturated soil is analyzed in this study. For that, the topographical and geological characteristics of the site were obtained and managed by GIS software. In the procedure of the study, slope angle, cohesion, friction angle, unit weight of soil were obtained and constructed as a spatial database layer. Combining these data sets in a dynamic model based on Newmark's displacement analysis, the landslide displacements were estimated in each grid cell. In order to check out the possibility of the earthquake induced landslides, the level of the groundwater table is varied from dry to 80% saturated soil. In addition, in order to analyze the effect of the magnitude of earthquake and distance to epicenter, four different earthquakes epicenters were considered in the study area.

Accelerated DNA Adduct Formation in the Lung of the Nrf2 Knockout Mouse Exposed to Diesel Exhaust

  • Aoki, Yasunobu;Sato, Hiromi;Nishimura, Noriko;Takahashi, Satoru;Itoh, Ken;Yamamoto, Masayuki
    • Proceedings of the Korea Environmental Mutagen Society Conference
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    • 2002.05a
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    • pp.36-42
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    • 2002
  • Diesel exhaust (DE) has been recognized as a noxious mutagen and/or carcinogen, because its components can form DNA adducts. Mechanisms governing the susceptibility to DE and the efficiency of such DNA adduct formation require clarification. The transcription factor Nrf2 is essential for inducible and/or constitutive expression of a group of detoxification and antioxidant enzymes, and we hypothesized that the nrf2 gene knockout mouse might serve as an excellent model system for analyzing DE toxicity. To address this hypothesis, lungs from nrf2(-/-) and nrf2(+/-) mice were examined for the production of xenobiotic-DNA adducts after exposure to DE (3 $mg/m^{3}$ suspended particulate matter) for 4 weeks. Whereas the relative adduct levels (RAL) were significantly increased in the lungs of both nrf2(+/-) and nrf2(-/-) mice upon exposure to DE, the increase of RAL in the lungs from nrf2(-/-) mice exposed to DE were approximately 2.3-fold higher than that of nrf2(+/-) mite exposed to DE. In contrail, cytochrome P4501Al mRNA levels in the nrf2(-/-)mouse lungs were similar to those in the nrf2(+/-) mouse lungs even after exposure to DE, suggesting that suppressed activity of phase II drug-metabolizing enzymes is important in giving ise to the increased level of DNA adducts in the Nrf2-null mutant mouse subjected to DE. Importantly, severe hyperplasia and accumulation of the oxidative DNA adduct 8-hydroxydeoxyguanosine were observed in the bronchial epidermis of nrf(-/-) mite following DE exposure. These results demonstrate the increased susceptibility of the nrf2 germ line mutant mouse to DE exposure and indicate the nrf2 gene knockout mouse nay represent a valuable model for the assessment of respiratory DE toxicity.

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