• 대기
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• 제20권2호
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• pp.153-160
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• 2010

In this paper, an attempt has been made to build and test self-configuring weather sensor networks and internet based observation system to gather atmospheric data. The aim is to provide integrated or real-time weather information in standard form using network data access protocol. This system was successfully developed to record weather information both digital as well as visual using sensor network and web-enabled surveillance cameras. These data were transformed by network based data access protocol to access and utilize for public domain. The competed system has been successfully utilized to monitor different types of weather. The results show that this is one of the most useful weather monitoring system.

• Journal of Microbiology and Biotechnology
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• 제34권6호
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• pp.1276-1286
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• 2024

The environment has been identified as an origin, reservoir, and transmission route of antibiotic resistance genes (ARGs). Among diverse environments, freshwater environments have been recognized as pivotal in the transmission of ARGs between opportunistic pathogens and autochthonous bacteria such as Aeromonas spp. In this study, five environmental strains of Aeromonas spp. exhibiting multidrug resistance (MDR) were selected for whole-genome sequencing to ascertain their taxonomic assignment at the species-level and to delineate their ARG repertoires. Analyses of their genomes revealed the presence of one protein almost identical to AhQnr (A. hydrophila Qnr protein) and four novel proteins similar to AhQnr. To scrutinize the classification and taxonomic distribution of these proteins, all Aeromonas genomes deposited in the NCBI RefSeq genome database (1,222 genomes) were investigated. This revealed that these Aeromonas Qnr (AQnr) proteins are conserved intrinsic resistance determinants of the genus, exhibiting species-specific diversity. Additionally, structure prediction and analysis of contribution to quinolone resistance by AQnr proteins of the isolates, confirmed their functionality as quinolone resistance determinants. Given the origin of mobile qnr genes from aquatic bacteria and the crucial role of Aeromonas spp. in ARG dissemination in aquatic environments, a thorough understanding and strict surveillance of AQnr families prior to the clinical emergence are imperative. In this study, using comparative genome analyses and functional characterization of AQnr proteins in the genus Aeromonas, novel Aeromonas ARGs requiring surveillance has suggested.

• The Korean Journal of Pain
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• 제37권1호
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• pp.41-50
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• 2024

Background: Recognizing the seriousness of the misuse and abuse of medical narcotics, the South Korean government introduced the world's first narcotic management system, the Narcotics Information Management System (NIMS). This study aimed to explore the recent one-year opioid prescribing patterns in South Korea using the NIMS database. Methods: This study analyzed opioid prescription records in South Korea for the year 2022, utilizing the dispensing/administration dataset provided by NIMS. Public data from the Korean Statistical Information Service were also utilized to explore prescription trends over the past four years. The examination covered 16 different opioid analgesics, assessed by the total number of units prescribed based on routes of administration, type of institutions, and patients' sex and age group. Additionally, the disposal rate for each ingredient was computed. Results: In total, 206,941 records of 87,792,968 opioid analgesic units were analyzed. Recently, the overall quantity of prescribed opioid analgesic units has remained relatively stable. The most prescribed ingredient was oral oxycodone, followed by tapentadol and sublingual fentanyl. Tertiary hospitals had the highest number of dispensed units (49.4%), followed by community pharmacies (40.2%). The highest number of prescribed units was attributed to male patients in their 60s. The disposal rates of the oral and transdermal formulations were less than 0.1%. Conclusions: Opioid prescription in South Korea features a high proportion of oral formulations, tertiary hospital administration, pharmacy dispensing, and elderly patients. Sustained education and surveillance of patients and healthcare providers is required.

• Journal of Microbiology and Biotechnology
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• 제22권4호
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• pp.530-534
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• 2012

A real-time PCR assay was developed and validated inhouse specifically for the detection of Clostridium perfringens (Cl. perfringens) in meats and vegetables by comparing with the culture method. The detection limit of the real-time PCR assay in phosphate-buffered saline was $10^2$ CFU/ml. When the two methods were compared in food samples inoculated with Cl. perfringens, the culture method detected 52 positives, whereas real-time PCR detected 51 positives out of 160 samples. The difference was without statistical significance (p>0.05). Real-time PCR assay is an option for quality assurance laboratories to perform standard diagnostic tests, considering its detection ability and time-saving efficiency.

• 생명과학회지
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• 제16권1호
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• pp.58-63
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• 2006

모 조선수리업에 근무하는 1,086명 중 석면에 노출되는 작업공정에 10년 이상 근무한 근로자 118명을 대상으로 단면조사연구를 수행하였다. 연구대상자들에 대해 흥부방사선검사, 폐기능검사와 미국의 산업안전보건청 석면표준, 의학적 감시 프로그램(OSHA asbestos standard, medical surveillance program)에 따라 국내 실정에 맞게 일부 편집한 설문조사를 시행하였고 아울러 이들의 작업장에 대한 작업환경측정 자료도 분석하였다. 흉부방사선검사상 석면관련 폐질환 소견의 유병율은 118명의 근로자중 16명으로 $13.6\%$였다. 흉부방사선검사상 정상군에 비해 석면관련 폐질환 유소견군에서 유의한 요인들은 폐기능검사상 이상소견, 기침, 가래, 호흡기 질환의 과거력, 근무력이었다. 본 연구 결과를 통해 볼 때 폐기능검사 소견상 이상소견, 기침과 가래의 임상증상을 호소하거나 호흡기질환의 과거력, 20년 이상의 근무력이 있는 근로자에 대해서는 석면관련 폐질환의 엄격한 관리가 필요할 것으로 생각된다. 그리고, 본 연구에서 관련성 여부를 완전히 배제할 수 없었던 요인들에 대해서는 향후 광범위한 전향적 연구를 통하여 연관성을 규명하여 석면노출 사업장의 의학적 감시 프로그램에 적극 활용되기를 기대한다.

• 디지털융복합연구
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• 제11권9호
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• pp.289-299
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• 2013

본 연구의 목적은 현재 질병관리본부에서 사용하고 있는 건강보험 청구자료 기반의 결핵환자 분류기준을 고도화하여 보다 효과적인 결핵환자감시체계의 토대를 제공하기 위해 수행되었다. 이를 위해 건강보험심사평가원의 2009년 1년간 결핵상병으로 청구된 81,199명 중 10%인 8,118명을 표본추출한 후 실제 결핵환자인지에 대해서 의무기록 조사를 실시하여 조사가 완료되고, 국민건강보험공단 건강보험청구 자료와 매칭이 완료된 7,132명을 최종 분석대상자로 하였다. 결핵환자분류를 위한 모형을 개발하여 평가한 결과 결핵과 관련된 임상전문가 의견과 통계적 분류 알고리즘이 종합적으로 고려된 의사결정나무모형이 가장 우수한 모형으로 평가되었다. 의사결정나무 모형에 따른 결핵분류모형의 주요 독립변수는 연령, 최초 청구시점의 결핵약제 종류수, 최초 청구시점의 이용 의료기관 유형, 최초 청구시점의 청구결핵검사 종류, 2008년 결핵약 투약일수, 최초 청구시점 결핵약제 투약일수, 최초 청구시점 결핵상병 종류로 나타났다. 이 모형의 향상도는 최고 11.8이였으며, 개발된 모형에서 분류된 1~5유형까지 적용하여 청구된 자료 중 결핵이 아님을 예측할 경우, 민감도는 90.6%, 양성예측도는 96.1%, 정분류율은 87.6%로 나타나, 현재 질병관리본부에서 사용하는 청구2회 이상, 약제 2제 이상 모형(민감도 82.6%, 양성예측도 95%, 정분류율 80%)보다 우수한 모형인 것으로 나타났다.

• 수산경영론집
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• 제34권1호
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• pp.137-156
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• 2003

Increasingly, leisure time is being used for outdoor recreational activities, and fishing is one of the principal forms of marine recreation. Marine recreational fishing is a popular activity in Korea and this activity has led to the development of a sector of substantial social and economic value. Also it is considered as one of the important outdoor leisure industries in Korea. With rising of income level and development of marine outdoor leisure industries, social, economic demand increase of marine recreational fishing are showing us new advance ability of marine aquatic bio-industry. However the recreational use of fish stocks has become an important consideration in the public and environmental economic analysis of management aspect of fishing, having grown considerably over recent years to reach a level in Korea where the fish stocks and coastal ecosystem has become a significant management problem. we are inevitably facing marine environmental deterioration and overfishing in marine recreational fishing. In this study, not only resources and environmental problems which are occurred by recreational fishers, but also illegal fishing behaviors and other problems such as market's failure are going to analyze basic management theories and methods of recreational fishing through mathematical principals and economic rents which maximize net social benefits. In view of the likelihood of marine recreational fishers adopting high rates of discount, the conservation of fish resources would appear to require continual public surveillance and control of the physical yield and condition of the fish stocks and the optimal use level. The institutional management of recreational fisheries is the way of escaping the collapse of recreational fisheries just like as the situation of management's failure of commercial fisheries worldwide. One of the effective management measure is a license system. In this system, optimal fee is paid by recreational fishers, which prevent them from overfishing, environmental problems to some extents and carry out the optimal number of outings. And money obtained by license fee should be spent for more improvement fishing culture and welfare for marine recreational fishing. Marine recreational fishing is to be promoted under sound conservation and management principles.

• 수산경영론집
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• 제48권3호
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• pp.15-32
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• 2017

This article's aim is to review the jurisprudence which has emerged pursuant to the international dispute settlement provisions and to provide a provisional expectation as to the future of international dispute settlement under "UNCLOS". Globally, marine fisheries play an important role in ocean biodiversity and the food security of millions of people, providing a vital source of high-quality dietary protein and supporting individuals' livelihoods and income. In the 1982 Convention, the establishment of co-operative mechanisms for effective monitoring, control, surveillance and enforcement, decision-making procedures facilitating the adoption of such measures of conservation and management, and the promotion of the peaceful settlement of disputes are called for. In this study, 'Northeast Asian Sea' means that the Yellow/East China Sea, the East Sea, the Ohotsk Sea, the Kamchaka Sea, the Alaska Sea, and the Bering Sea surrounded by Korea, China, Japan, Russia, U.S.A. and Canada including their EEZs. There are several bilateral fisheries agreements existing in Northeast Asian area, the Fisheries Agreement between Republic Korea and Japan, between Republic of Korea and China, between China and Japan, between Republic Korea and U.S.A., between Republic Korea and Russia, between Russia and Japan, And there are several regional fisheries organizations existing in Northeast Asian area, for example NPAFC(Convention for the Conservation of Anadromous Stocks in the North Pacific Ocean), CBSPC (Convention on the Central Bering Sea Pollack Conservation), PICES(North Pacific Marine Science Organization), NPFC(North Pacific Fishery Commi-ssion) etc. It analyzed the proliferation of bilateral treaties and multilateral treaties due to the adoption of the EEZ in Northeast Asia reviewed the strengthening of management rights on the high seas marine living resources and marine environment preservation of regional fisheries organizations. In view of the changes in the international fisheries mechanism this paper suggested the future direction of the country in overseas fisheries. We concluded as follows. We shall apply bilateral treaties first, regional fisheries organizations' treaties secondly, and provisions under "UNCLOS" for dispute settlement last.

• 한국임상약학회지
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• 제13권2호
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• pp.72-81
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• 2003

Adverse drug reaction (ADR) may increase hospital admission, morbidity and mortality and adding extra cost to healthcare expenditures. AIMS: This study was performed to identify the types of ADR being reported in a tertiary hospital, and to find out the ways to improve current ADR monitoring system. To investigate the attitudes of hospital pharmacists towards, and their understanding of ADR reporting. METHODS: Of 117 reports submitted to the pharmacy department during 3 months survey period, A questionnaire survey of 75 randomly selected hospital pharmacists was conducted. RESULT: Of the report was from patients aged between 60 and 70. The medical department with the high frequency in ADR reporting was Internal Medicines $(60\%)$. The most common ADR manifestations were gastrointestinal complaints $(47.8\%)\;and\;80\%$ of the reported cases were mild in their severity. The most common drugs suspected of causing ADR were CNS drugs which accounted for $38.4\%.\;55.5\%$ of respondent were aware of the need to education and information about ADR monitoring. The important reasons for unreporting ADR were unknown of how to report ADRs $(94.6\%)$. CONCLUSIONS: An ADR reporting system based on reporting by staff pharmacists has been effective increasing the number of reported reactions and pharmacist involvement in monitoring patients for ADRs. Pharmacists have the knowledge and responsibility to contribute to ADR reporting program. A great opportunity exists for pharmacists to contribute in this area of patient care.

• 수산경영론집
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• 제33권1호
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• pp.1-18
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• 2002

The observer program is being utilized In various fishing areas and fisheries internationally and nationally due to the its expected effectiveness in fisheries management and the collection of bioeconomic data necessary in fisheries management policy. The timely gathered data by observers play substantially a major role in decision-making fisheries policy such as the change in management measures, the application of season closure and area closure and etc. The expected effectiveness of the observer program In fisheries management, generally mentioned, is that it would lead to the increase in stock size from which the level of harvest would consequently increases. This study is aimed to analyze this tentatively expected effectiveness of the observer program in fisheries management. The changes in stock size and the level of harvest over time are analyzed under the observer program assuming the fishermen bear the cost of the observer program by investigating the change in fisherman's fishing activity under the observer program and by combining this changed activity with the biological model. The level of fishing efforts of fishermen was decreased from the results of the increase in fishing cost caused by the observer cost and the decrease in catchable stock size restricted by observers. This reduced level of fishing efforts enables stock size to increase over time and therefore, the expected level of harvest increases as time goes on. Another benefit under the observer program is to reduce management costs from the fact that fishermen are responsible for the cost of the observer program and the avoidance cost of fisherman responding to the fisheries regulation could be eliminated from the surveillance of observer. Therefore, it may possible to accomplish the cost-efficient fisheries management policy.