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State of dental treatment among disabled patients at K university hospital pediatric dentistry (K 대학 소아치과에 내원한 장애인의 구강진료 실태)

  • Kim, Chang-Hee;Park, Jae-Hong;Kim, Jin;Kim, Sun-Ju
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.3
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    • pp.357-368
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    • 2009
  • The purpose of this study was to examine the state of dental treatment among disabled patients by the type of disability. After the medical records of 531 disabled patients who received treatment at the pediatric dentistry in K university hospital, the following findings were given: 1. As for age distribution by year, the rate of patients aged 10 or down rose to 42.5 from 5.1 percent, and the 16-20 age group increased from 16.7 to 24.8 percent. But the rates of patients aged between 11 and 15 and aged 21 and up were on the rise(p<.05). 2. Concerning the type of disability by year, there was an increase in the number of patients with brain lesions, mental retardation, developmental disorder and Down's syndrome(p<.05). As to the number of dental caries by the type of disability, the patients with heart diseases had the most dental caries that numbered 8.49, followed by Down's syndrome, metal retardation, brain lesions, the other disabilities and developmental disorder. 3. In relation to dental treatment experiences by the type of disability, the patients with developmental disorder(57.5%) received the most dental treatment, followed by mental retardation, the other disabilities, brain lesions, Down's syndrome and heart diseases(p<.05). 4. Regarding general anesthesia experience by the type of disability, the patients with mental retardation(31.6%) were put under general anesthesia the most, followed by developmental disorder, brain lesions, the other disabilities, heart diseases and Down's syndrome(p<.05). In conclusion, nationwide efforts to nurture separate dental personnels responsible for the disabled, to expand relevant facilities and to improve the health care insurance are required to promote the oral health of disabled children.

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Characterization and Application of a Novel Thermostable Glucoamylase Cloned from a Hyperthermophilic Archaeon Sulfolobus tokodaii

  • Njoroge, Rose Nyawira;Li, Dan;Park, Jong-Tae;Cha, Hyun-Ju;Kim, Mi-Sun;Kim, Jung-Wan;Park, Kwan-Hwa
    • Food Science and Biotechnology
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    • v.14 no.6
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    • pp.860-865
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    • 2005
  • A gene for a putative glucoamylase, stg, of a hyperthermophilic archae on Sulfolobus tokodaii was cloned and expressed in Escherichia coli. The recombinant glucoamylase (STGA) had an optimal temperature of $80^{\circ}C$ and was extremely thermostable with a D-value of 17 hr. The pH optimum of the enzyme was 4.5. Being different from fungal glucoamylases, STGA hydrolyzed maltotriose (G3) most efficiently. Gel permeation chromatography and sedimentation equilibrium analytical ultracentrifugation analysis showed that the enzyme existed as a dimer. STGA was stable enough to hydrolyze liquefied com starch to glucose in 4 hr at $90^{\circ}C$ with a yield of95%. Comparison of the $k_{cat}$ values for the hydrolysis and the reverse reaction at $75^{\circ}C$ and $90^{\circ}C$ indicated that glucose production by STGA was more efficient at $90^{\circ}C$ than $75^{\circ}C$. Therefore, STGA showed great potential for application to the industrial glucose production process due to its high thermostability.

Comparison of Piroxicam Pharmacokinetics and Anti-Inflammatory Effect in Rats after Intra-Articular and Intramuscular Administration

  • Park, Chan Woong;Ma, Kyung Wan;Jang, Sun Woo;Son, Miwon;Kang, Myung Joo
    • Biomolecules & Therapeutics
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    • v.22 no.3
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    • pp.260-266
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    • 2014
  • This study evaluated the pharmacokinetic profile and therapeutic efficacy of piroxicam (PX), a long acting non-steroidal anti-inflammatory drug for the treatment of arthritis, following intra-articular (IA) injection in comparison to the pharmacokinetic profile and therapeutic efficacy of PX after intramuscular (IM) injection. In the pharmacokinetic study in rats, systemic exposure and pharmacokinetic parameters of PX after a single IA dose were compared with systemic exposure and pharmacokinetic parameters of PX after administration of the same dose IM (0.6 mg/kg). The anti-inflammatory and analgesic effects of IA PX were evaluated simultaneously in a monoiodoacetate-induced osteoarthritis rat model. The plasma PX concentration rapidly rose following IA injection, and it was comparable to the plasma PX concentration following IM injection, suggesting the rapid efflux of the drug molecule from the joint cavity. However, in the efficacy study, the IA PX administration significantly reduced the knee swelling by reducing the level of prostaglandin $E_2$ in the joint, compared to that following administration of IA vehicle and after administration of the IM PX dose. In addition, we found that the anti-inflammatory and anti-nociceptive efficacies of IA PX were synergistically increased upon co-treatment with hyaluronic acid (HA), a potent agent for the treatment of osteoarthritis, at the weight ratio of 1:1 or 1:2, and these effects were more pronounced than those following administration of HA or PX alone. In conclusion, this study demonstrated the efficacy of the IA use of PX alone and/or in combination with HA in osteoarthritis.

Lineament analysis in the euiseong area using automatic lineament extraction algorithm (자동 선구조 추출 알고리즘을 이용한 경북 의성지역의 선구조 분석)

  • 김상완
    • Economic and Environmental Geology
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    • v.32 no.1
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    • pp.19-31
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    • 1999
  • In this study, we have estimated lineaments in the Euiseong area, Kyungbuk Province, from Landsat TM by applying the algorithm developed by Kim and Won et al. which can effectively reduce the look direction bias associated with the Sun's azimuth angle. Fratures over the study area were also mapped in the field at 57 selected sites to compare them with the results from the satellite image. The trends of lineaments estimated from the Landsat TM images are characterized as $N50^{\circ}$~70W, NS~$N10^{\circ}$W, and $N10^{\circ}$~$60^{\circ}$E trends. The spatial distribution of lineaments is also studied using a circular grid, and the results show that the area can be divided into two domains : domain A in which NS~$N20^{\circ}$E direction is dominant, and domain B in which west-north-west direction is prominent. The trends of lineaments can also be classified into seven groups. Among them, only C, D and G trends are found to be dominant based upon Donnelly's nearest neighbor analysis and correlations of lineament desities. In the color composite image produced by overlaying the lineament density map of these C-, D-, and G-trends, G-trend is shown to be developed in the whole study area while the eastern part of the area is dominated by D-trend. C-trend develops extensively over the whole are except the southeastern part. The orientation of fractures measured at 35 points in the field shows major trends of NS~$N30^{\circ}$E, $N50^{\circ}$~$80^{\circ}$W, and N80$^{\circ}$E~EW, which agree relatively well with the lineaments estimated form the satellite image. The rose diagram analysis fo field data shows that WNW-ESE trending discontinuities are developed in the whole area while discontinuities of NS~$N20^{\circ}$E are develped only in the estern part, which also coincide with the result from the satellite image. The combined results of lineaments from the satellite image and fracture orientation of field data at 22 points including 18 minor faults in Sindong Group imply that the WNW-ESE trend is so prominent that Gumchun and Gaum faults are possibly extended up to the lower Sindong Group in the study area.

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The Comparative Study about General Education Curriculum of Engineering College in the United states (미국의 공과대학 교양교육과정에 대한 비교 연구)

  • Kim, Myoung-Lang;Park, Hye-Young;Chang, Sun-Young
    • Journal of Engineering Education Research
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    • v.10 no.1
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    • pp.5-19
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    • 2007
  • A general education course is different from a major course in an engineering college. Therefore, they influence a learning outcomes according to their forms and contents. In particular, an engineering college in korea is open to argument against a general education course. Because a general education course has to observe the criterion of ABEEK. Consequently, the purpose of this study is to compare general education courses of engineering colleges in USA. For it, this study analyzes the completion method and academic area of a general education course. In result, this study suggests the property and implication of a general education course in an engineering college.

Analysis of Arterial Stiffness by Age Using Pulse Waveform Measurement of 5-levels Graded Pressure (5단계 가압 맥파측정에 의한 연령별 혈관 경화도 분석)

  • Kwon, Sun-Min;Kang, Hee-Jung;Yim, Yun-Kyoung;Lee, Yong-Heum
    • Korean Journal of Acupuncture
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    • v.27 no.2
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    • pp.107-120
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    • 2010
  • Objectives : The aim of this study is to measure pulse waveforms by applying 5-level graded pressure, and selecting optimum pulse waveforms. Also to proposing the possibility of using AW(Area of the 1/3 upper height of h1) rate in respect to AT(Total Area) for risk assessment of hypertension or arteriosclerosis is another aim of the study. Methods : Pulse waveforms of normotensive were measured by 5-level graded pressure. The pulse waveforms well reflecting properties of blood vessel(having the largest h1) were selected for optimum pulse waveforms. Various parameters(h-parameter, t-parameter, and others) of optimum pulse waveforms were analyzed. AIx(Augmentation index) was calculated by height-parameters to assess arterial stiffness. The area rate of the 1/3 upper height for h1 in respect to total area was analyzed according to aging. Results : According to aging 1. in height-parameter, h2 and h3 were increased but h5 was decreased. 2. In time-parameter, t2, t3, and t5 were getting short. 3. Area of systolic period was increased, and that of diastolic period decreased. 4. AIx rose by aging. 5. AW was significantly increased despite no changes in AT. Conclusions : By analyzing optimum pulse waveforms of 5-level graded pressure method, we could complement weakness of single graded pressure method. Also, possibility of applying the AW rate to risk assessment of hypertension or arteriosclerosis was confirmed in normotensive population which might not be assessed by AIx.

Growth Optimization of Photorhabdus luminescens Isolated from Entomopathogenic Nematode Heterorhabditis bacteriophora (병원성 선충 Heterorhabditis bacteriophora에서 분리된 공생 박테리아 Photorhabdus luminescens의 생장조건)

  • Yoo, Sun Kyun;Randy Gaugler;Christopher W. Brey
    • Microbiology and Biotechnology Letters
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    • v.29 no.2
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    • pp.104-109
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    • 2001
  • The yield of infective juveniles of Heterorhabditis bacteriophora (Tf strain) in vitro monoxenic liquid culture was improved significantly as the amount of symbiont biomass, Photorhabdus sp. strain Tf, increased. To investigate the influence of abiotic factors on the growth and biomass production of Photorhabdus sp. strain Tf, triplicate flask cu1tmes were performed. The optinal temperature and medium pH for the growth of Photorhahdus sp. strain Tf were 30$^{\circ}$C and between pH 5.5-7.3, respectively. Aeration also improved greatly growth and yield of biomass of Photorhabdus sp. strain Tf. Photorhabdus sp. strain Tf in batch fermentation showed growth-associated pattem in terms of pigment production, and the pH of culture medium rose steadily until growth stopped dUling the fermentation. Both pigment production and culture pH rise would be useful parameters indicating a reliable growth of Photorhabdus sp. strain Tf.

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The Explosion Prevention Method for Electrolytic Motor Start Capacitors using Current Characteristic (통전전류 특성을 이용한 모터 기동용 전해 커패시터 폭발 방지 방법)

  • Kim, Jae-Hyun;Park, Jin-Young;Park, Kwang-Muk;Bang, Sun-Bae;Kim, Yong-Un
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.12
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    • pp.1836-1843
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    • 2017
  • In this paper, we investigated fire cases those are believed to be caused by explosion of a electrolytic motor start capacitor. Using two types of commercially available electrolytic motor start capacitors, capacitor current and the possibility of capacitor explosion were tested. And the ignition possibility of the internal material leaked from a capacitor was also tested. In addition, experiments were conducted to see if the fire could spread when a capacitor was exposed to an external flame. From our test we observed that the current of the electrolytic motor start capacitor rose continuously to a certain level by product, if the capacitor was continuously energized with working voltage, and then the capacitor was exploded. The gas and liquid leaked from the capacitor by the explosion could ignite by an electric arc and an external flame. The capacitor current at explosion was different product by product, but each product had a certain current level at explosion. And the increase rate of the capacitor current until explosion was 24% and 31% for the products used in the experiment. We proposed the capacitor explosion prevention method that cuts off power when the capacitor current rises to a certain threshold level. The proposed method can be used if the current of the applied electrolytic motor start capacitor rises continuously and then the capacitor is exploded at a certain current level when the capacitor is energized continuously.

A Study on the Regional Conditions and Characteristics of Apartment Ownership Resale (지역별 아파트 분양권 실태 및 특성 연구)

  • Kim, Sun-Woong;Suh, Jeong-Yeal
    • Journal of Cadastre & Land InformatiX
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    • v.48 no.2
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    • pp.5-20
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    • 2018
  • This paper aims to analyze characteristic by the cities focused on the ratio of new apartment resale that is one of the apartment unit sale market, which has been increased recently. So, this study examined characteristics of population, apartment trade & sale, housing with 162 cities and counties and performed multiple regression analysis with dependent variable, ratio of new apartment resale. As a result. the factors affecting the ratio of new apartment resale are 7variables, apartment sales rate, transfer of ownership, apartment turnover rate, sale volume, regional apartment rate, population increasing rate, housing average apartment sale price rate. In terms of the increase in apartment sales prices, the rate of sales price increase was relatively low in areas where the transaction rate for apartment sales is high, and the number of apartment sales right transactions increased as the number of other ownership transfers rose. As a result, the data will be based on the improvement of the government's policies and systems to stimulate the transaction focused on the real estate agents in the apartment market.

Elimination of Lancet-Related Needlestick Injuries Using a Safety-Engineered Lancet: Experience in a Hospital

  • An, Hye-sun;Ko, Suhui;Bang, Ji Hwan;Park, Sang-Won
    • Infection and chemotherapy
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    • v.50 no.4
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    • pp.319-327
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    • 2018
  • Background: Lancet-related needlestick injuries (NSIs) occur steadily in clinical practices. Safety-engineered devices (SEDs) can systematically reduce NSIs. However, the use of SEDs is not active and no study to guide the implementation of SEDs was known in South Korea. The lancet-related NSIs may be eliminated to zero incidence using a SED lancet with effective sharp injury protection and reuse prevention features. Materials and Methods: We implemented a SED lancet by replacing a conventional prick lancet in a tertiary hospital in a sequential approach. A spot test of the new SED was conducted for 1 month to check the acceptability in practice and a questionnaire survey was obtained from the healthcare workers (HCWs). A pilot implementation of the SED lancet in 2 wards was made for 1 year. Based on these preliminary interventions, a hospital-wide full implementation of the SED lancet was launched. The incidence of NSIs and cost expenditure before and after the intervention were compared. Results: There were 29 cases of conventional prick lancet-related NSIs for 3 years before the full implementation of SED lancet. The proportion of prick lancet-related NSIs among yearly all kinds of NSIs during two years before the pilot study was average 11.7% (22/188). Pre-interventional baseline incidence of all kinds of NSIs was 7.01 per 100 HCW-years. After the full implementation of SED lancet, the lancet-related NSIs became zero in the 2nd year (P = 0.001). The average direct cost of 18,393 US dollars (USD) per year from device and post-exposure medical care before the intervention rose to 20,701 USD in the 2nd year of the intervention. The incremental cost-effectiveness ratio was 210 USD per injury avoided. Conclusion: The implementation of a SED lancet could eliminate the lancet-related NSIs to zero incidence. The cost increase incurred by the use of SED lancet was tolerable.