• Korean Journal of Veterinary Research
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• v.25 no.2
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• pp.203-207
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• 1985

This study was performed to evaluate the effect of succinylcholine chloride as a muscular relaxant in deers. Succinylcholine chloride was administered for the harvesting of velvet antler to 62 sika deers which were farmed in the surburb of Seoul. The results obtained were as follows. 1. The more the dose of succinylcholine the earlier the time to immobilization and the slower the time to recover (p<0.05). 2. The optimal intramuscular dose of succinylcholine was found to be 0.11~0.14mg per kg of body weight for sika deer. 3. The time to immobilization revealed the longest An 4~6 years group. The more the age the longer the time to recover (p<0.05).

• Journal of Veterinary Clinics
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• v.16 no.2
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• pp.239-247
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• 1999

We estimated the changes of ECG and electrolytes in serum after intravenous administration of Succinylcholine Chloride (SCC), 0.15 mg/kg in ten normal mongrel dogs (mean 13 kg). Hyperkalemia was observed in the highest level by 6.46$\pm$0.8 mEq/L at ten minutes after the administration of SCC. The ECG appeared temporary the most severe changes as the increased T wave, the disappeared P wave, the prolonged of conduction times (PR, QTc intervals and QRS complex), and arrhythmia as ventricular premature contraction at 3 and 5 minutes after the administration SCC. Therefore, the changes of ECG after administration of SCC were suggested to specific and independent from hyperkalemic changes. Because these changes were observed to differ from ECG by hyperkalemia, and the highest period of $K^＋$value in serum differ from the appearance period of severe changes of ECG and arrhythmia by SCC.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.65-68
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• 1999

This study was carried to get detailed information about the analeptic effect of yohimbine on succinylcholine muscle relaxant. Succinylcholine was administered intra- venously at a dose rate of 0.05 mg per kg of body weight and then ten minutes after the succinylcholine injection, yohimbine was administered intravenously at a dose rate of 0.1 mg per kg of body weight. The results obtained were as follows. 1. Induction time of muscle relaxation was fast and favourable as 38 seconds. 2. Mean arousal time and mean walk time were significantly shortened by yohimbine administration in the dogs immobilized with succinylcholine (p＜0.01). 3. Heart rate was slightly increased after succinylcholine administration, and increased significantly after yohimbine administration compared to the control group (p＜0.05). 4. Glucose concentration was slightly increased after succinylcholine administration, and decreased after yohimbine administration compared to the control group.

• Journal of Veterinary Clinics
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• v.7 no.1
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• pp.407-414
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• 1990

This study was performed to evaluate the effects of doxapram after succinylcholine treatment. Succinylcholine was administered intravenously at a dose rate of 0.07 mg per kg of body weight and then ten minutes after the injection of succinylcholine doxapram was administered intravenously at a dose rate of 2 mg per kg of body weight. The results obtained were as follows : 1. Recovery time in dog given doxapram after succinylcholine treatment was shortened comparing with control group. 2. The changes in respiratory rate revealed a maximal increase immediately after the injection of doxapram. Thereafter respiratory rate gradually decreased, and revealed normal levels 20 minutes after the injection of doxapram. 3. The changes in heart rate revealed a maximal increase immediately after the injection of doxapram. Thereafter heart rate gradually decreased, but remained above the levels of control group. 4. Although arrhysthmias were observed after treatment of succinylcholine, these were disappeared after doxapram treatment. And there was no another change on electrocardiograms.

• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.49-51
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• 1986

Atracurium was used in 10 parturients undergoing elective cesarian section under general Anesthesia. An initial bolus of 0.4 mg/kg of the atracurium was injected after recovery from succinylcholine block. Complete neuromuscular block resulted in all cases. Muscular relaxation was maintained by incremental dose of 0.2mg/kg of atracurium. Administration of atracurium did not cause significant change in blood pressure, pulse rate and infants Apgar score. The residual neuromuscular block could be antagonized at the end of the procedure by mixture of 0.005mg/kg glycopyrrolate and 0.03 mg/kg of neostigmine. In all parturients, antagonism was adequate as evidenced by respiratory response and head lift test. Atracurium may be advantageous in parturients undergoing cesarian section under general anesthesia cause it maintained cardiovascular stability, is non-cumulative, is readily antagonized by neostigmine and has no deleterious effect on the newborn.

• The Korean Journal of Pain
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• v.12 no.1
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• pp.81-86
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• 1999

Background: Essential hyperhidrosis is a condition with excessive sweating, which may be localized in any parts of the body. Thoracic sympathectomy has been a surgical procedure for the management of hyperhidrosis. Methods: We studied 30 ASA I and II patients suffering from severe hyperhidrosis. Bilateral upper thoracoscopic sympathectomy of $T_{2-4}$ was performed in 30 patients under general anesthesia. Anesthesia was induced with 2.5% thiopental sodium 5 mg/kg and succinylcholine chloride 1 mg/kg and was maintained with enflurane 1~2 Vol% and $N_2O-O_2$ mixture adjusted to maintain $SpO_2$ greater than 96%. During anesthesia, invasive arterial pressure, heart rate, EKG, $SpO_2$ and capnography were monitored. Skin temperature was measured with thermister probes attached to the index finger of each hand. An increase in temperature after cautery confirmed success of the sympathectomy. Results: There were 14 men and 16 women whose ages ranged from 16 to 46 years old (mean age 22.2). Of these patients, 13 patients had complained of palm-sole hyperhidrosis, 9 of palm-sole-axilla hyperhidrosis, 4 of palm-sole-face hyperhidrosis and 4 of palm-sole-axilla-face hyperhidrosis. The provocative factors of excessive sweating were tension and stress from interpersonal relationships. There was positive familial history in 37%. The most common complication was compensatory hyperhidrosis in 23 patients comprising 76%. Other complication included peumothorax (4 patients), hemothorax (1 patient), ipsilateral Horner's syndrome (1 patient) and paresthesia of right arm (1 patient). The degree of satisfaction was graded as good, fair and poor with 15, 12 and 3 patients, respectively. Conclusions: Thoracoscopic sympathectomy with VATS is an efficient, safe and minimally invasive surgical procedure for essential hyperhidrosis.