• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.24 no.2
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• pp.87-95
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• 2011

Objective : Subcorneal pustular dermatosis is a rare, chronic neutrophilic dermatoses that was first described in 1956. The eruption is characterized by flaccid pustules grouped in a circinate pattern on normal or erythematous skin. We treated a case of subcorneal pustular dermatosis in one patient; there have been no former reports of this disease treated by oriental medicine. We present this case because we considered it to be useful as a possible Oriental medicine treatment for subcorneal pustular dermatosis, and something that canbe used for further study of neutrophilic dermatoses. Method : We used herbal medication, acupuncture, herbal wet dressing, herbal ointment, cupping therapy and phototherapy during treatment. We assessed symptoms during treatment and also carried out blood tests through out. Result : We observed and treated a case of subcorneal pustular dermatosis patient and after treatment the patient's objective and subjective symptoms showed noticeable improvement. Conclusion : We suggest that subcorneal pustualr dermatosis can be treated by Oriental medicine therapy effectively. We expect these study results will help provide useful evidence of Oriental medicine as an effective treatment for subcorneal pustualr dermatosis.

• Korean Journal of Veterinary Research
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• v.53 no.2
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• pp.125-127
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• 2013

Canine Subcorneal pustular dermatosis (CSPD) represents a sterile, superficial, pustular skin disease of unknown cause but may be a variant of pemphigus foliaceus. A 7-year-old, intact female, mixed dog presented with 3-month history of pruritic multiple pustules and crusts. Direct smears from intact pustules revealed numerous nondegenerate neutrophils, some acantholytic cells, and bacterial culture was negative. Histologic examination of lesional skin showed subcorneal pustules filled with neutrophils and acantholytic cells. The direct immunofluorescence tests stained with IgG, IgA, IgM, C3 were negative. Oral administration of dapsone (1 mg/kg/q8h) was initiated and it was reduced to 1 mg/kg/q12h with good control of the lesions.

• Journal of Veterinary Clinics
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• v.37 no.6
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• pp.339-341
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• 2020

Subcorneal pustular dermatosis (SPD) is a rare pustular skin disorder of dogs. Dapsone is treatment of choice, but ineffective in some cases. Therapeutic alternatives are limited and less effective. In humans, successful results with oral retinoid have been reported. To describe successful treatment of a dog that developed SPD with acitretin as an alternative drug of dapsone. A 7-year-old male neutered miniature schnauzer was presented with generalized pustules and crusts. SPD was diagnosed based on physical, cytological, and histopathological examination with direct immunofluorescence test. In this report, we describe a case of canine SPD treated initially by dapsone with poor response that improved with acitretin. Acitretin could be considered as an alternative drug in canine SPD.