• The Journal of the Acoustical Society of Korea
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• v.35 no.5
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• pp.358-367
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• 2016

SSL (Sound Source Localization) has been applied to several applications such as man-machine interface, video conference system, smart car and so on. But in the process of sound source localization, angle estimation error is occurred mainly due to the non-linear characteristics of the sine inverse function. So an approach was proposed to decrease the effect of this non-linear characteristics, which divides the microphone's covering space into narrow regions. In this paper, we proposed an optimal space dividing way according to the pattern of microphone array. In addition, sound source's 2-dimensional position is estimated in order to evaluate the performance of this dividing method. In the experiment, GCC-PHAT (Generalized Cross Correlation PHAse Transform) method that is known to be robust with noisy environments is adopted and triangular pattern of 3 microphones and rectangular pattern of 4 microphones are tested with 100 speech data respectively. The experimental results show that triangular pattern can't estimate the correct position due to the lower space area resolution, but performance of rectangular pattern is dramatically improved with correct estimation rate of 67 %.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.12
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• pp.4819-4834
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• 2015

The spectral efficiency of cellular networks can be improved when proximate users engage in device-to-device (D2D) communications to communicate directly without going through a base station. However, D2D communications that are not properly designed may generate interference with existing cellular networks. In this paper, we study resource allocation and power control to minimize the probability of an outage and maximize the overall network throughput. We investigate three power control-based schemes: the Partial Co-channel based Overlap Resource Power Control (PC.OVER), Fractional Frequency Reuse based Overlap Resource Power Control (FFR.OVER) and Fractional Frequency Reuse based Adaptive Power Control (FFR.APC) and also compare their performance. In PC.OVER, a certain portion of the total bandwidth is dedicated to the D2D. The FFR.OVER and FFR.APC schemes combine the FFR techniques and the power control mechanism. In FFR, the entire frequency band is partitioned into two parts, including a central and edge sub-bands. Macrocell users (mUEs) transmit using uniform power in the inner and outer regions of the cell, and in all three schemes, the D2D receivers (D2DRs) transmit with low power when more than one D2DRs share a resource block (RB) with the macrocells. For PC.OVER and FFR.OVER, the power of the D2DRs is reduced to its minimum, and for the FFR.APC scheme, the transmission power of the D2DRs is iteratively adjusted to satisfy the signal to interference ratio (SIR) threshold. The three schemes exhibit a significant improvement in the overall system capacity as well as in the probability of a user outage when compared to a conventional scheme.

• Journal of Plant Biotechnology
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• v.46 no.4
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• pp.255-273
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• 2019

Orchids are indispensable to the floriculture industry due to their unique floral organization. The flowers have two outer whorls of tepals including a lip (labellum), and two inner whorls, pollinia and gynostemiun (column). The floral organization and development is controlled at the molecular level, mainly by the MADS-box gene family, comprising homeotic genes divided into type I and type II groups. The type I group has four sub-groups, Mα, Mβ, Mγ, and Mδ, playing roles in seed, embryo, and female reproductive organ development; the type II group genes form classes A, B, C, D, and E, which are a part of the MIKC^C subgroup with specific roles in florigenesis and organization. The coordinated functioning of these classes regulates the development of various floral whorls. The availability of genome and transcriptome sequence data for Phalaenopsis equestris offers an opportunity to validate the ABCDE model of flower development. Hence, this study sought to characterize the MADS-box gene family and elucidate of the ABCDE model. A total of 48 identified MADS-box proteins, including 20 type I [Mα (12), Mγ (8)] and 28 type II [MIKC^C (27), MIKC*(1)] members, were characterized for physico-chemical features and domains and motifs organization. The exon-intron distribution and the upstream cis-regulatory elements in the promoter regions of MADS-box genes were also analysed. The discrete pace of duplication events in type I and type II genes suggested differential evolutionary constraints between groups. The correlation of spatio-temporal expression pattern with the presence of specific cis-regulatory elements and putative protein-protein interaction within the different classes of MADS-box gene family endorse the ABCDE model of floral development.

• Food Science of Animal Resources
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• v.33 no.6
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• pp.715-722
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• 2013

Heugu (Korea Black Cattle) is one of the indigenous cattle breeds in Korea; however there has been severe lack of genomic studies on the breed. In this study, we report the first whole genome resequencing of Heugu at higher sequence coverage using Illumina HiSeq 2000 platform. More than 153.6 Giga base pairs sequence was obtained, of which 97% of the reads were mapped to the bovine reference sequence assembly (UMD 3.1). The number of non-redundantly mapped sequence reads corresponds to approximately 28.9-fold coverage across the genome. From these data, we identified a total of over six million single nucleotide polymorphisms (SNPs), of which 29.4% were found to be novel using the single nucleotide polymorphism database build 137. Extensive annotation was performed on all the detected SNPs, showing that most of SNPs were located in intergenic regions (70.7%), which is well corresponded with previous studies. Of the total SNPs, we identified substantial numbers of non-synonymous SNPs (13,979) in 5,999 genes, which could potentially affect meat quality traits in cattle. These results provide genome-wide SNPs that can serve as useful genetic tools and as candidates in searches for phenotype-altering DNA difference implicated with meat quality traits in cattle. The importance of this study can be further pronounced with the first whole genome sequencing of the valuable local genetic resource to be used in further genomic comparison studies with diverse cattle breeds.

• BMB Reports
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• v.50 no.4
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• pp.208-213
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• 2017

Vascular endothelial growth factor (VEGF) is an essential cytokine that has functions in the formation of new blood vessels and regression of cardiac hypertrophy. VEGF/VEGF-receptor-1 (VEGFR1) signaling plays a key role in the regression of cardiac hypertrophy, whereas VEGF/VEGFR2 signaling leads to cardiac hypertrophy. In this study, we identified the prohypertrophic role of miR-374 using neonatal rat ventricular myocytes (NRVMs). Our results showed that overexpression of miR-374 activated G protein-coupled receptor-mediated prohypertrophic pathways by the inhibition of VEGFR1-dependent regression pathways. Luciferase assays revealed that miR-374 could directly target the 3'-untranslated regions of VEGFR1 and cGMP-dependent protein kinase-1. Collectively, these findings demonstrated that miR-374 was a novel pro-hypertrophic microRNA functioning to suppress the VEGFR1-mediated regression pathway.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2111-2114
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• 2016

Opisthorchiasis is a health problem in Thailand particularly in northeast and north regions where have been reported the highest of cholangiocarcinoma. Active surveillance is required, therefore a cross-sectional surveyed was conducted in Nong Bunnak sub-district of Nakhon Ratchasima province, Thailand. A total of 367 participants were selected by multistage sampling from 5 villages located near natural water resources. Participants completed a predesigned questionnaire containing behavior questions regarding liver fluke disease, covering reliability and validity knowledge (Kuder-Richardon-20) = 0.80, attitude and practice (Cronbach's alpha coefficient) = 0.82 and 0.79, respectively. Descriptive statistics included frequencies, percentages, means, and standard deviations. The majority of the participants were female (58.3%), age group between 21-30 years old (42.5%), with primary school education (59.9%), occupation in agriculture (38.1%), and married (80.9%). They had past histories of raw fish consumption (88.3%), stool examination (1.4%), anti-parasite medication used (4.6%). Heads of villages, village health volunteers, television, and village newstations were the main sources for disease information. Participants had a moderate level of behavior regarding liver fluke disease. The mean scored of knowledge regarding liver fluke life cycle, transmission, severities, treatment, prevention and control was 10.9 (SD=0.5), most of them had a moderate level, 95.1%. The mean score for attitude regarding liver fluke prevention and control was 45.7 (SD=9.7), and for practice was 30.6 (SD=10.5). Participants had a moderate level of attitude and practice, 94.5% and 47.7, respectively. This study indicates that health education is required in this community including stool examination for liver fluke as further active surveillance screening.

• Journal of Korean Society for Atmospheric Environment
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• v.24 no.5
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• pp.538-550
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• 2008

Radon is an invisible, odorless, and radioactive gas. It is formed by the disintegration of radium, which is a decay product of uranium. Some amounts of radon gas and its products are present ubiquitously in the soil, water, and air. Particularly high radon levels occur in regions of high uranium content. Although radon is permeable into indoor environment not only through geological features (bed rock and permeability) but also through the construction materials and underground water, the radiation from the geological features is generally main exposure factor. So there can be a problem in a certain space such as the underground and/or relatively poor ventilation condition. In this study, a GIS technique was used in order to investigate spatial distribution of radon measured from sub- way stations of 1 thru 8 in Seoul, Korea in 1991, 1998, 2001, and 2006. Spatial analysis was applied to reproduce the radon distribution. We utilized spatial analysis techniques such as inverse distance weighted averaging (IDW) and kriging techniques which are widely used to relate between different spatial points. To validate the results from the analyses, the jackknife technique for an uncertainty test was performed. When the number of measuring sites was less than 100 and also when the number of omitted sites increased, the kriging technique was better than IDW. On the other hand, when the number of sites was over 100, IDW technique was better than kriging technique. Thus the selection of analytical tool was affected sensitives by the analysis based on the number of measuring sites.

• Journal of Korea Multimedia Society
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• v.12 no.3
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• pp.345-353
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• 2009

It is for sure that a stable game managing system is absolutely needed to accept simultaneous interfacing of many users for P2P on-line game system. The proposed P2P on-line game system in this paper is able to get smart and stable game managing taking care of extensive players through reorganizing numerous RS(Region Server) and mutual communications among RS's which can be avoid congestion on one region. Moreover, it is possible to synchronize for game nodes in time stamp utilizing Global Zone Buffer of Monitoring Server which leads to breakup loads. The system manages middleware layers in the so-called sub area, and it is able to execute no matter how big the game sizes are. That means, in some ways, we got everything we try to ensure such as the problems of high cost server and stabilization of message transmission. This paper welcomes to prove efficiency of the suggested system through the simulation.

• Journal of information and communication convergence engineering
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• v.8 no.6
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• pp.645-650
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• 2010

In this paper, we present the effect of binocular cues which plays crucial role for the visualization of a stereoscopic or 3D image. This study is useful in extracting depth and disparity information by image processing technique. A linear relation between the object distance and the image distance is presented to discuss the cause of cybersickness. In the experimental results, three dimensional view of the depth map between the 2D images is shown. A median filter is used to reduce the noises available in the disparity map image. After the median filter, two filter algorithms such as 'Gabor' filter and 'Canny' filter are tested for disparity visualization between two images. The 'Gabor' filter is to estimate the disparity by texture extraction and discrimination methods of the two images, and the 'Canny' filter is used to visualize the disparity by edge detection of the two color images obtained from stereoscopic cameras. The 'Canny' filter is better choice for estimating the disparity rather than the 'Gabor' filter because the 'Canny' filter is much more efficient than 'Gabor' filter in terms of detecting the edges. 'Canny' filter changes the color images directly into color edges without converting them into the grayscale. As a result, more clear edges of the stereo images as compared to the edge detection by 'Gabor' filter can be obtained. Since the main goal of the research is to estimate the horizontal disparity of all possible regions or edges of the images, thus the 'Canny' filter is proposed for decipherable visualization of the disparity.

• Journal of Microbiology
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• v.40 no.3
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• pp.211-218
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• 2002

A 4.8-kb DNA fragment encoding the P-450 type hydroxylase and ferredoxin genes was cloned from Pseudonocardia autotrophica IFO 12743 that can convert vitamin D$\_$3/ into its hydroxylated active forms. In order to isolate the P-450 gene cluster in this organism, we designed PCR primers on the basis of the regions of an oxygen binding site and a heme ligand pocket that are general characteristics of the P-450 hydroxylase. Sequencing analysis of the BamHI fragment revealed the presence of four complete and one incomplete ORFs, named PauA, PauB, PauC, and PauD, respectively. As a result of computer-based analyses, PauA and PauB have homology with enoyl-CoA hydratase from several organisms and the positive regulators belonging to the tetR family, respectively. PauC and PauD show similarity with SuaB/C proteins and ferredoxins, respectively, which are composed of P-450 monooxygenase systems for metabolizing two sulfonylurea herbicides in Streptomyces griseolus PauC shows the highest similarity with another CytP-450$\_$Sca2/ protein that is responsible for production of a specific HMG-CoA reductase inhibitor, pravastatin, in S. carbophilus. Cultures of Steptomyces lividans transformant, containing the P-450 gene cluster on the pWHM3 plasmid, was unable to convert vitamin D$\_$3/ to its hydroxylated forms.