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Outcome of the Teratoma in Pediatric Surgical Patients (소아외과 환자에서 기형종의 치료 결과)

  • Lee, Ho-Kyun;Park, Kyung-Sub;Choi, Soo-Jin-Na;Kim, Shin-Kon;Chung, Sang-Young
    • Advances in pediatric surgery
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    • v.9 no.2
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    • pp.94-97
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    • 2003
  • The teratoma is a unique complex neoplasm and is one of the most frequent pediatric tumors originated from the extragonadal germ cells. Mature teratoma is composed of mature differentiated tissues, while immature teratoma always contains embryonic tissues of variable degrees of immaturity, especially in the neuroepithelial elements. Diagnosis of teratoma is relatively easy by conventional radiologic study, but the immaturity can be identified only by histopathological examination. Between January 1993 to December 2002, 63 cases of teratoma were operated and analysed retrospectively at the Chonnam University Hospital Female to male ratio was about 3:1 and age distribution was relatively even. Among 63 cases, gonadal teratoma was the most common (52.4%), followed by sacrococcygeal (25.4%), retroperitoneal (9.5%) and mediastinal teratoma (9.5%). Fifty-six cases were mature teratomas and seven were immature teratomas. Alpha-fetoprotein (AFP) was elevated in 4 of 6 immature cases, but in 2 of 51 mature ones Elevated AFP progressively returned to normal range by 1 month after operation in all. Complete excision of the mass was performed, and major complication was not noticed. In five immature cases, PEB chemotherapy (Cisplatin, Etoposide, Bleomycin) was performed. Two of 2 cases in histological grade II were well tolerated to the aggressive chemotherapy. One of three cases in grade III expired due to severe bone marrow depression, and two of them expired by tumor recurrences. In conclusion, immature teratoma in histological grade III showed high potentiality of recurrence. Therefore, postoperative chemotherapy has to be applied to the high graded immature tumors.

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Effect of Cultivar, Drying Agent and Preservative on Quality Changes of Fall Harvested Oat Hay (품종, 건조제 및 보존제의 처리가 추계수확 연맥건초의 품질변화에 미치는 영향)

  • 한건준;김동암
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.16 no.4
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    • pp.315-326
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    • 1996
  • An experiment was carried out to determine effect of cultivar, drying agent concentration and preservative on the moisture content, temperature and quality changes of fall harvested oat(Avena sativa L.) hay during field curing and storage. The main plots consisted of the cultivar such as 'Foothill' and 'Swan', the subplots consisted of drying agent concentration such as 7Skg/ha(C1), lOSkglha(C2) and control(C0) and the sub-subplots consisted of preservative such as buffered acid(BA), lactic bacteria inoculant(LB) and control(C0). Moisture contents of 'Foothill' and 'Swan' oat cultivar at harvest were 635.5 and 385.4%DW(Dry weight), respectively, but the final moisture contents of the oat cultivars were 117 and 86%DW. The moisture content of cut oat was not affeded by drying agent concentration. Core temperature of baled 'Swan' oat hay was a little higher than that of 'Foothill' and no consistent preservative effect was found. Total nitrogen content of 'Swan' oat hay was 3.08% and that of 'Foothill' oat hay was 3.45%(P<0.05). Drying agent treatment increased total nitrogen content of 'Swan'(P <0.05), but preservative had no effect. Crude fiber content of oat cultivar was increased as the curing progressed(P<0.05) and the difference of crude fiber content of oat cultivar was maintained through the whole curing period. Effect of drying agent concentration on crude fiber content was not found after preservation. Crude fiber content of 'Swan' oat hay was higher than that of 'Foothill' by 1.O% in ADF and 3.1 % in NDF(P<0.05). No preservative effect was found in crude fiber content. According to RFV of oat cultivar at harvest, forage quality of 'Foothill' and 'Swan' was Prime and Grade 1, respectively, but that of both cultivm was above Grade 2 at the final curing day. RFV of the stored 'Foothill' and 'Swan' oat hay was 122 and 114(P<0.05), respectively, and the quality of oat hay was classified as Grade 1 and 2, respectively, according to the forage quality standard assigned by AFGC.

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Water Quality Simulation of Juam Reservoir Depend on Total Pollution Loads Control (총량규제에 따른 주암호의 장래 수질 예측)

  • Jang, Sung-Ryong;An, Ki-Sun;Kwon, Young-Ho;Han, Jae-Ik
    • Journal of Environmental Science International
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    • v.19 no.1
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    • pp.39-45
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    • 2010
  • When the Juam multipurpose dam which is connected with existing large water supply facilities is finished, water environment is changed from stream to lake. The changed quality of water should be examined. In this study, the result of water quality forecasting is analysed and an effective management plan of water quality is presented. Tn this study, the WASPS model that is a dynamic water quality simulation model was selected to forecast the water quality. This model forecasts movement of change of pollutants. For an application of the model, the subject areas were divided into seventeen sub-areas by considering change temperature depending measuring points and on depth of water. Meteorological data collected by the meteorological observatory and data about quality measured by the Korea Water Resources Development Corporation were used for an operation of the model. As a result of quality examination through quality data and estimated pollutant loading, the water quality environment criterion was grade II and the nutritive condition was measured as meso-graphic grade. In this study, an effective management was planned to improve water quality by reducing pollution load. According to the result of examination, when more than 30% of BOD was reduced it was recorded that the environment standard of water quality was improved to the second grade.

A Study of Dyeing Properties of Cotton Fabrics Under Supercritical CO2 Depending on Dyestuff : by C.I. Disperse orange 155, C.I. Disperse red 167 (초임계 유체 염색용 염료에 따른 면 섬유의 염색 특성 : C.I. Disperse orange 155, C.I. Disperse red 167)

  • Choi, Hyunseuk;Kim, Hunmin;Jeon, Taeyoung
    • Textile Coloration and Finishing
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    • v.34 no.2
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    • pp.93-101
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    • 2022
  • In this study, the dyeing properties of supercritical fluid dyed cotton fabrics were investigated which use two types of dyes, such as C.I. Disperse orange and C.I. Disperse red 167. Dyeing temperature, pressure and leveling time were equally applied at 130 ℃, 250 bar, and 60 minutes with reference to the related literature, and experiments were performed at concentrations of 0.04, 0.1, 0.4 and 0.8 % o.w.f with different concentrations. Dyeability was confirmed through measurement of washing fastness and color coordinate, and a calibration curve of each dye was drawn up and the absorbance of the residual dye was measured to confirm the amount of residual dye and the dye exhaustion rate at the corresponding concentration. As a result of color difference measurement, as the concentration increased, the L* value decreased and the K/S value increased. However, as the concentration increased, the increase in K/S value decreased compared to the input amount, and this tendency was more obvious in C.I. Disperse red 167 than in C.I. Disperse orange 155. The dye exhaustion rate which was calculated by using the amount of residual dye in the pot was also C.I. Disperse orange 155 was 96.16 % and C.I. Disperse red 167 was 94.57 %. However, as the dyeing concentration increased, the dye exhaustion rate decreased, that C.I. Disperse orange was 95.33 % and C.I. Disperse red 167 was 90.63 %. As a result of the washing fastness test for both dyes, dyed samples of which concentrations were 0.4 and 0.8 % o.w.f decreased by 0.5 ~ 1.0 grade. This is predicted because the dye did not completely adhere to the amorphous region of the cotton fiber and the dye simply adsorbed. The fastness to rubbing also maintained at least grade 3-4 up to the 0.1 % o.w.f concentration, but at the concentration of 0.4 % o.w.f or higher, it fell to grade 1 or lower, showing a very poor friction fastness.

Test & Evaluation for the Configuration Optimization of Thrust Chamber in 70 N-class N2H4 Thruster (Part II: Pulse-mode Performance According to the Chamber Length Variation) (70 N급 하이드라진 추력기의 추력실 최적설계와 시험평가 (Part II: 추력실 길이변화에 따른 펄스모드 성능특성))

  • Jung, Hun;Kim, Jong Hyun;Kim, Jeong Soo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.18 no.1
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    • pp.50-57
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    • 2014
  • A ground hot-firing test (HFT) was conducted to take out the optimal design configurations for the thrust chamber of 70 N-class liquid rocket engine under development. Monopropellant grade (purity: ${\geq}98.5%$) hydrazine was adopted as a propellant for the HFT, and three kinds of thrust chambers having characteristic lengths ($L^*$) of 2.79, 2.95, and 3.13 m were selected for their performance evaluation. It is revealed through the test and evaluation that the increase of the $L^*$ leads to a performance degradation in the test condition specified, and pulse response performance of the development model shows superior characteristics to commercialized hydrazine thrusters.

Hypofractionated radiotherapy for early glottic cancer: a retrospective interim analysis of a single institution

  • Lee, Jeong Won;Lee, Jeong Eun;Park, Junhee;Sohn, Jin Ho;Ahn, Dongbin
    • Radiation Oncology Journal
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    • v.37 no.2
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    • pp.82-90
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    • 2019
  • Purpose: To evaluate the results of hypofractionated radiotherapy (HFX) for early glottic cancer. Materials and Methods: Eighty-five patients with cT1-2N0M0 squamous cell carcinoma of the glottis who had undergone HFX, performed using intensity-modulated radiotherapy (IMRT, n = 66) and three-dimensional conformal radiotherapy (3D CRT, n = 19) were analyzed. For all patients, radiotherapy was administered at 60.75 Gy in 27 fractions. Forty-three patients received a simultaneous integrated boost (SIB) of 2.3-2.5 Gy per tumor fraction. Results: The median follow-up duration was 29.9 months (range, 5.5 to 76.5 months). All patients achieved complete remission at a median of 50 days after the end of radiotherapy (range, 14 to 206 days). The 5-year rates for locoregional recurrence-free survival was 88.1%, and the 5-year overall survival rate was 86.2%. T2 stage was a prognostic factor for locoregional recurrence-free survival after radiotherapy (p = 0.002). SIB for the tumor did not affect disease control and survival (p = 0.191 and p = 0.387, respectively). No patients experienced acute or chronic toxicities of ≥grade 3. IMRT significantly decreased the dose administered to the carotid artery as opposed to 3D CRT (V35, p < 0.001; V50, p < 0.001). Conclusions: Patients treated with HFX achieved acceptable locoregional disease control rates and overall survival rates compared with previous HFX studies. A fraction size of 2.25 Gy provided good disease control regardless of SIB administration.

Effects of Critical Thinking Disposition and Empathy on Cultural Competency in Dental Hygiene Students

  • Hwang, Ji-Min;Han, Ji-Hyoung
    • Journal of dental hygiene science
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    • v.18 no.1
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    • pp.24-31
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    • 2018
  • This study investigated the effects of critical thinking and empathy on the cultural competence of dental hygienists and students. A total of 529 dental hygiene students were randomly sampled and included as subjects. PASW Statistics for Windows ver. 18.0 was used to obtain the following results. Among the critical thinking sub-domains, cognitive integration was the highest and the lowest. Empathic ability had the highest acceptance factor among the sub-domains. Cultural competence was the highest among the sub-domains, while cultural knowledge was the lowest. According to their general characteristics, subject age, grade, religion, and economic level influenced the cultural capacity. Cultural awareness and sensitivity were high when there were foreign visiting experiences. Cultural awareness, sensitivity, skills, and knowledge were high when subjects had experienced multicultural education (p<0.05). Cultural awareness, sensitivity, skill, experience, and knowledge were correlated with critical thinking and cultural competence, among which cultural sensitivity showed the highest correlation (p<0.001). There was a correlation between cultural awareness and sensitivity, skill, and experience among the empathy and cultural competency sub-domains (p<0.001). The factors influencing cultural awareness included intellectual integration, openness, prudence, and perspective-taking (p<0.001). The factors influencing cultural sensitivity included intellectual integration, openness, and empathic concern (p<0.001). The factors influencing cultural skill included intellectual integration, creativity, and conductivity (p<0.001). The factors influencing cultural experience included prudence, objectivity, perspective-taking, and personal distress (p<0.001). Finally, the factors influencing cultural knowledge included creativity and conductivity (p<0.001). The results indicate that dental hygiene students should be equipped with cultural competence to enhance critical thinking and empathy required by the modern society and optimized dental hygiene courses should be provided for multicultural subjects.

Hydrolysis by Alcalase Improves Hypoallergenic Properties of Goat Milk Protein

  • Jung, Tae-Hwan;Yun, Sung-Seob;Lee, Won-Jae;Kim, Jin-Wook;Ha, Ho-Kyung;Yoo, Michelle;Hwang, Hyo-Jeong;Jeon, Woo-Min;Han, Kyoung-Sik
    • Food Science of Animal Resources
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    • v.36 no.4
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    • pp.516-522
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    • 2016
  • Goat milk is highly nutritious and is consumed in many countries, but the development of functional foods from goat milk has been slow compared to that for other types of milk. The aim of this study was to develop a goat milk protein hydrolysate (GMPH) with enhanced digestibility and better hypoallergenic properties in comparison with other protein sources such as ovalbumin and soy protein. Goat milk protein was digested with four commercial food-grade proteases (separately) under various conditions to achieve the best hydrolysis of αs -casein and β-lactoglobulin. It was shown that treatment with alcalase (0.4%, 60℃ for 30 min) effectively degraded these two proteins, as determined by SDS-PAGE, measurement of nonprotein nitrogen content, and reverse-phase high-performance liquid chromatography. Hydrolysis with alcalase resulted in a significant decrease in β-lactoglobulin concentration (almost to nil) and a ~40% reduction in the level of αs-casein. Quantification of histamine and TNF-α released from HMC-1 cells (human mast cell line) showed that the GMPH did not induce an allergic response when compared to the control. Hence, the GMPH may be useful for development of novel foods for infants, the elderly, and convalescent patients, to replace cow milk.

Preparation of Bi2O3-PbO-SrO-CaO Coating Sol for Wiring and Superconductivity and Its properties

  • Jung, Jee-Sung;Iwasaki, Mitusnobo;Park, Won-Kyu
    • Korean Journal of Materials Research
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    • v.17 no.3
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    • pp.147-151
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    • 2007
  • Cu-free multi-component sol, of which final oxide composition becomes $Bi_{1.9}Pb{0.35}SrCaO,\;Bi_{1.8}Pb_{0.2}SrCaO\;and\;Bi_{1.5}SrCaO$, respectively, was prepared through sol-gel route and coated on a bare Cu substrate. Starting materials were metal-alkoxides as follows.; [$Bi(OC_{2}H_{5})_{3}\;Pb(O^{1}C_{3}H_{7})_{2},\;Sr(O^{i}C_{3}H_{7})_{2},\;Ca(OC_{2}H_{5})_{2}$] as a reagent grade. Transparent light yellowish sol was obtained in the case of $Bi_{1.9}Pb_{0.35}SrCaO\;and\;Bi_{1.8}Pb_{0.2}SrCaO$ composition and $Bi_{1.5}SrCaO$ composition's sol was light greenish. Each sol was repeatedly dip-coated on Cu substrate four times and pre-heated at $400^{\circ}C$ and finally heat-treated in the range of $740{\sim}900^{\circ}C$. In the results, crystalline phases confirmed by XRD were (2201) orthorhombic and monoclinic phases. However, only $Bi_{1.9}Pb_{0.35}SrCaO_{x}$ composition showed pseudo-superconductive behavior after heat-treatment at $900^{\circ}C$ for 12 seconds and then onset temperature was 77 K, even though it did not exhibit zero resistance below Tc.

Transformation of C9 Aromatics on Metal Loaded Mordenite (금속담지 Mordenite 에 의한 C9 Aromatics 전환반응)

  • Lee, Hak-Sung;Kim, Byung-Kyu;Park, Bok-Soo
    • Applied Chemistry for Engineering
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    • v.1 no.2
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    • pp.240-248
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    • 1990
  • The catalytic activity and selectivity of metal loaded H-mordenite for transalkylation of $C_9$ aromatics were studied in a continuous flow fixed bed reactor under high pressure. Nickel loaded H-mordenite(T-Ni) catalyst showed high activity and slow decay of activity. Molybdenum and nickel loaded H-mordenite(T-NiMo) catalyst also showed high activity and suppressed coking of hydrocarbons. The selectivity of xylene for T-Ni and T-NiMo catalysts decreased with temperature, but that for T catalyst(commercial grade) monotonically increased with temperature within the experimental range. The performance of T-Ni and T-NiMo catalysts was better than that of T catalyst in terms of initial activity and its decay. The addition of Mo improved slightly stability of T-Ni catalyst.

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