• Title/Summary/Keyword: structural regulation

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A Study on Development of U-Manless Overload Regulation System (U-중차량 무인과적단속시스템 구축방안에 대한 연구)

  • Jo, Byung-Wan;Kim, Do-Keun;Choi, Hae-Yun;Park, Jung-Hun;Yoon, Suk-Min
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.20 no.3
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    • pp.387-392
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    • 2007
  • Overloaded Vehicles are one of biggest of hazard in durability decrease of roads and bridges. Thus, regulation was put in force about overloaded vehicles to reserve this problem. However, existing system had many problems. For these reasons, this paper presents solutions of U-intelligent overload vehicles regulation system based on manless and wireless for fixing of problems of existing system and construction of u-lTS. With this in mind, we studied about composition method of system, applications of USN, design of system controller, WCDMA/HSDPA and we verified performance of WIM Sensors in this paper.

The Effects of Maternal Parenting Variables on Preschool Children's Self Regulation (어머니의 양육관련 변인과 유아의 자기조절 능력과의 관련성 탐색)

  • Cho, Young-Suk;Lee, Yang-Hee
    • Journal of the Korean Home Economics Association
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    • v.47 no.6
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    • pp.51-66
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    • 2009
  • The purpose of this study was to develop a model for preschool children's self regulation by examining the effects of maternal parenting variables on preschool children's self regulation. The subjects were 1219 mothers of 4- to 6-year-old preschool children attending kindergarten or child care centers located in Seoul and Kyunggi Province, Korea. For data analysis, exploratory factor analysis(EFA) and confirmatory factor analysis(CFA) were applied to the survey data in the first phase and structural equation modeling(SEM) analysis in the second phase. The major results of this study were as follows: maternal parenting stress and maternal behavior were the most direct influential variables on preschool children's self-regulation. Moreover, maternal parenting efficacy was indirectly mediated through maternal behavior.

Analysis and Priorities of State Regulation of the Labor Market in Crisis Conditions

  • Yurii Shpak;Vitaliy Davydenko;Vаsyl Pasichnyk;Valentyna Zhukovska;Viktoriya Ivanyuta
    • International Journal of Computer Science & Network Security
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    • v.23 no.12
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    • pp.181-186
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    • 2023
  • The main purpose of the study is to analyze the features of state regulation of the labor market in a crisis. Structural shifts in the labor market are due to the transformation of public and economic relations in today's globalized world. Increasing competition, the development of the knowledge economy, information technology, changes in the content and forms of labor require updating the labor market regulation system. The research methodology implies the use of modern methods of analysis. The analysis of the features of state regulation of the labor market in crisis conditions is carried out.

The effect of child, adolescent period's father-child relationship on interpersonal problems among married women : The mediating role of impaired objective self and emotional regulation difficulties (어린 시절 부-자녀관계가 대인관계문제에 미치는 영향 : 대상적 자기손상과 정서조절곤란의 매개효과)

  • Lee, MunHee
    • Journal of Family Relations
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    • v.23 no.1
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    • pp.97-120
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    • 2018
  • Objectives: The purpose of this study is to examine the process of how a parent-child relationship affects an impaired objective self, emotional regulation difficulties, and, consequently, interpersonal problems. Methods: To carry out this study, a total of 467 married women were surveyed on their parent-child relationship, impaired objective self, and emotional regulation difficulties. The resulting data was interpreted using descriptive statistics analysis, correlation analysis, and structural equation models analysis. Results: First, the parent-child relationship shows negative correlations with an impaired objective self, emotional regulation difficulties, and interpersonal problems. In addition, an impaired objective self, emotional regulation difficulties, and interpersonal problems show positive correlations with one another. Second, an impaired objective self and emotional regulation difficulties mediate the parent-child relationship and intrapersonal problems consecutively. Conclusions: This indicates that efforts to mitigate an impaired objective self and to intervene in difficulties in emotional regulation can help address intrapersonal difficulties. Finally, this paper examines how this study affects the ongoing discussion on this matter and its implications for future studies.

Conformational Switch and Functional Regulation of Proteins (단백질의 구조 전환과 기능 조절)

  • Yu, Myeong-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.11b
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    • pp.3-6
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    • 2001
  • In common globular proteins, the native form is in its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, and internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of a 1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of a 1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of a 1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

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Conformational Switch and Functional Regulation of Proteins (단백질의 구조 전환과 기능 조절)

  • 유명희
    • Electrical & Electronic Materials
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    • v.14 no.12
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    • pp.3-6
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    • 2001
  • In common globular proteins, the native form is n its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, ad internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of $\alpha$1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of $\alpha$1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of $\alpha$1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

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Conformational Switch and Functional Regulation of Proteins (단백질의 구조 전환과 기능 조절)

  • 유명희
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.11a
    • /
    • pp.3-6
    • /
    • 2001
  • In common globular proteins, the native form is in its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these Proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, and internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of ${\alpha}$1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of ${\alpha}$1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of e 1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

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The Relationship between Child Abuse and Emotional Regulation: Mediating Effect of Rejection Sensitivity (아동의 학대 경험과 정서조절의 관계: 거부민감성의 매개효과)

  • Kang, Ha-Eun;Cho, Young-A
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.11
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    • pp.618-627
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    • 2017
  • Recently, the number of cases of child abuse has been increasing and, consequently, the social interest in this issue is increasing. The purpose of this study is to examine the relationship between child abuse, rejection sensitivity and emotional regulation and to identify the mediating effects of rejection sensitivity in the relationship between child abuse and emotional regulation. For this purpose, a survey on child abuse, rejection sensitivity and emotional regulation was administered to 217 elementary school students in the fourth, fifth and sixth grades, who had been reported as victims of child abuse or managed as suspected child abuse victims in the Seoul, Gyeonggi, Gangwon, Chungcheong, and Gyeongsang regions. The data was analyzed using structural equation modelling and bootstrapping. The findings showed that child abuse was significantly negatively correlated with emotional regulation, but positively correlated with rejection sensitivity. Emotional regulation was significantly negatively correlated with rejection sensitivity. Second, the structural equation analysis also revealed that rejection sensitivity fully mediated the relationship between child abuse and emotional regulation. This means that child abuse has an indirect effect on emotional regulation through rejection sensitivity. Therefore, when counseling abused children with emotional regulation problems, it is important for the counselors to include interventions designed to lower their rejection sensitivity.

Mothers' Parenting Behaviors and School-Aged Children's Strategies and Competence of Emotional Regulation (어머니의 양육행동과 학령기 아동의 정서조절 전략 및 정서조절 능력간의 관계)

  • Park Seo-Jung;Kim Soon-Ok
    • Journal of Families and Better Life
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    • v.23 no.4 s.76
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    • pp.35-53
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    • 2005
  • In this study, the influence of mothers' parenting behaviors on children's strategies and competence of emotional regulation was examined. Further, the mediating effects of children's active-social support seeking and aggressive strategies on the above relationship were explored. The participants were W mother-child pairs. The children were 5th and 6th graders at two elementary schools in Kyunggi province and Kwangju metropolitan area The data were analyzed with descriptive statistics, factor analysis, Cronbach's alpha, Pearson correlations, standard multiple regressions and structural equation modeling analysis by LISREL 8.3. The main results of this study were as follows: (1) The more the mothers coached children with affection and reasoning, the more adaptive emotional regulation the children had; whereas children tended to have maladaptive emotional regulation in response to the mothers' rejecting and forceful parenting behaviors. Also, when children were coached by mothers with love, reasoning and consistent restriction, they used more active-social support seeking strategies, whereas they used more aggressive strategies when the mothers coached children with rejecting and forceful parenting behaviors. The more the mothers were rejecting, forceful and intervening, the more the children used passive-avoidant strategies. (2) The more the children used active-social support seeking strategies and the less the children used aggressive strategies, the more likely they had adaptive emotional regulation. The more the children used aggressive strategies, the more likely they had maladaptive emotional regulation. (3) Children's active-social support seeking strategies played a partial mediating role between mothers' affectionate and reasoned coaching and children's adaptive emotional regulation. These strategies, on the other hand, played a full mediating role between mothers' consistent restriction and children's adaptive emotional regulation. Children's aggressive strategies played a partial mediating role between mothers' rejecting and forceful parenting behaviors and children's maladaptive emotional regulation. Mothers' non-intervention had an influence on neither the children's aggressive strategies nor their maladaptive emotional regulation.