• Title/Summary/Keyword: structural regulation

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Development of the Evaluation Element for Fire Engineering Design (건축물의 성능적 내화설계 평가 요소기술 개발)

  • Kwon, In-Kyu;Kim, Heung-Youl
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2009.04a
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    • pp.410-414
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    • 2009
  • Performance based fire engineering design should be developed through basic survey and fundamental element such as analytic program for evaluation of fire performance of building. The basic elements will be expressed to the surveys of the structures of building laws, regulation and the fundamental elements consist of technical guidances contained design fires, heat analysis, determination of structural performance.

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Structural Mechanism for the Cellular Redox Regulation by the Thiol Specific Antioxidant Proteins

  • Park, Hee-Jeong;Kang, Sang-Won;Rhee, Sue-Goo;Ryu, Seong-Eon
    • Proceedings of the Korean Biophysical Society Conference
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    • 1997.07a
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    • pp.15-15
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    • 1997
  • Recent studies indicate that hydrogen peroxide (H$_2$O$_2$), which is one of the reactive oxygen species involved in the oxidative stress, is an intracellular secondary messenger in the signal transduction. A novel family of thiol specific antioxidant (TSA) enzymes with a peroxidase activity shows no sequence homology to previously known antioxidant enzymes.(omitted)

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A Structural Relationship between Self-regulation Efficacy, Task Difficulty Preference, Learning Immersion, and Academic Curiosity in Engineering College Freshmen (공과대학 신입생의 자기조절 효능감, 과제난이도 선호, 학습몰입, 학문적 호기심의 구조적 관계)

  • Hong, Hyojeong
    • Journal of Engineering Education Research
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    • v.25 no.6
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    • pp.14-22
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    • 2022
  • This paper is a basic study of college of engineering freshmen's adaptation to college life, and the relationship between sub-variables of academic self-efficacy, learning immersion, and academic curiosity is analyzed. And based on the results, a plan to support new students of the College of engineering is suggested.

Systems Thinking Perspective on the Collapse of Savings and Loan Banking System in Korea (저축은행 사태에 대한 시스템 사고적 고찰)

  • Ahn, Nam-Sung
    • Korean System Dynamics Review
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    • v.13 no.1
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    • pp.63-80
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    • 2012
  • This paper is aiming at providing the systems thinking perspective on the collapse of the savings and loan banking system in Korea. Two causal loop diagrams are developed to conduct the analysis: The first is focusing on the structural problems included in the establishment of S&L banking in 1990s. The later is developed based on the project financing mechanism by controlling the credit standard required during the due diligence. The result of this study shows that the main cause of the collapse of the S&L banking is the structural problem connected to real estate market including the failure of regulation.

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Structure Prediction of KiSS1-derived Peptide Receptor Using Comparative Modelling

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.9 no.2
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    • pp.136-143
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    • 2016
  • KiSS1-derived peptide receptor, a GPCR protein, binds with the hormone kiss peptin. They are important in the neuroendocrine regulation of reproduction and in the secretion of gonadotrophin-releasing hormone. Thus, analysing the structural features of the receptor becomes important. However, the three dimensional structure of the protein is unavailable. Hence in this study, we have performed the homology modelling of KiSS1-derived peptide receptor with 5 different templates. 30 models were constructed using two platforms - Easymodeller and ITasser. The optimal models were chosen based on the model validation. Two models were selected after validation. The developed models could provide useful for analysing the structural features of KiSS1-derived peptide receptor and their pathophysiological role in various disorders related to them.

A Study on Vehicle Frontal Structure for Crash Compatibility (상호 안전성 대응 차체 전방 구조에 관한 연구)

  • Shin, Jangho;Kim, Yun Chang;Kim, Hye Yeon
    • Journal of Auto-vehicle Safety Association
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    • v.3 no.2
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    • pp.11-16
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    • 2011
  • In recent years, rapid-increasing market share of compact cars and SUVs has brought for both consumer and automaker to pay more attention on crash compatibility between the compact passenger vehicles and the light trucks (i.e., Pickups and SUVs). Vehicle compatibility regarding both self and partner protection in frontal crash of different class vehicles is one of hot issues in vehicle safety. Furthermore, it is expected that the amendment of UNECE-Regulation 94 to implement compatibility issues in couple of coming years. In this study, conceptual design of compatibility compliant frontal vehicle structure which subjects to improve? the distribution of frontal crash loading and structural engagement between vehicles is introduced. The effects of proposed vehicle structure on both possible candidates (i.e. FWRB, FWDB and PDB) for a compatibility evaluation test procedure and car-to-car crash are also investigated.

The Hsp90 chaperone machinery: from structure to drug development

  • Hahn, Ji-Sook
    • BMB Reports
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    • v.42 no.10
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    • pp.623-630
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    • 2009
  • Hsp90, an evolutionarily conserved molecular chaperone, is involved in the folding, stabilization, activation, and assembly of a wide range of 'client' proteins, thus playing a central role in many biological processes. Especially, several oncoproteins act as Hsp90 client proteins and tumor cells require higher Hsp90 activity than normal cells to maintain their malignancy. For this reason, Hsp90 has emerged as a promising target for anti-cancer drug development. It is still largely unknown how Hsp90 can recognize structurally unrelated client proteins. However, recent progress in structural studies on Hsp90 and its interaction with various co-chaperones has broadened our knowledge of how the Hsp90 ATPase activity, which is essential for its chaperone function, is regulated and coupled with the conformational changes of Hsp90 dimer. This review focuses on the roles of various Hsp90 co-chaperones in the regulation of the Hsp90 ATPase cycle, as well as in the selection of client proteins. In addition, the current development of Hsp90 inhibitors based on the structural information will be discussed.

Measurement and Prediction Analysis of Ground and Structural Vibration Induced by Train Load (열차하중에 의한 지반 및 인접구조물의 진동 계측과 예측 해석)

  • 이주호;박광순;박경래;양신추
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1998.04a
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    • pp.365-370
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    • 1998
  • In this study, the method of analysis which is developed for calculating dynamic train loads and ground vibration by Shin-Chu Yang is verified comparing measurements of real structure. The results of analysis are agreed well with measurements of ground and structural vibration induced by passing train. The vibration level of analyzed results which is more than that of measured gives conservative result. To analyze frequency characteristics, the analyzed results are applied to the ISO environmental vibration regulation and reveal the possibility of application in analysis of frequency characteristics.

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A Structural Analysis between Financial Regulations and Security Industry through the Systems Thinking (시스템 사고를 통한 금융 규제와 보안 산업의 구조 분석)

  • Lee, Jeong-Ha
    • Korean System Dynamics Review
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    • v.16 no.4
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    • pp.31-50
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    • 2015
  • The purpose of this research is to understand a structural relationship between financial regulations and security industry based on the systems thinking perspective using causal loop analysis. As a result, the positive regulations on security technology against finance security incidents shrink the autonomy of the security industry and will deteriorate the competitiveness of the security industry through the unknown feedback loop. The conclusion provides the direction that policy makers understand causal loop diagram related current regulations and open enough to the consideration of the negative regulations.

A Study on Vertical Separation Regarding Paperless Trade Infrastructure (전자무역기반시설의 구조 분리에 관한 연구)

  • Roh, Jae-Whak
    • International Commerce and Information Review
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    • v.8 no.3
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    • pp.121-142
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    • 2006
  • Recently regarding the ownership and proper operational forms of paperless trade infrastructure has become an issue. In this research the structural separation approach, different from the behavioral regulation approach, has been adopted. Following the structural separation, the core e-trade infrastructure which is separated from a vertically integrated provider, can be operated by three different forms such as a private sector; a public sector; finally a consortium among participants. As another option, the separated whole infrastructure including both core and non-core can be operated by a independent private entity. However, this option is not interesting case to us. As the last option, it can be considered that a new wholesale independent company for the separated core-infra can be set up for running. Additionally, three other alternative ways such as accounting separation, division separation, or corporation separation with keeping same ownership are also demonstrated. However the cautious investigation on cost and benefits of vertical separation are strongly recommended by OECD and agrees with the conclusion of this study.

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