• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.43-43
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• 2010

We have characterized the parametric and functional properties of live cell and cancer cell according to plasma treatment conditions using Atmospheric Pressure (AP) Plasma with uniquely designed low temperature arc-free unit. AP plasma system showed very highly efficient capabilities of reacting and interfacing directly with live and cancer cells. The parametric results with the types of gases, applied power, applied gap, and process times on cells will be presented in accordance with functional studies of the works. The growth of cancer cells is directly influenced by AP plasma exposure with evaluating plasma conditions in several human cancer cells and understanding how plasma exposure alters molecular signaling pathways. The cells exhibit a slower or faster growth rates compared with untreated cells, depending on the cell types. These results strongly support the conclusion that alterations in one or more of each gene are responsible, at least in part, for plasma-induced apoptosis in cancer cells. In addition, it also will be presented that AP plasma has an important role for the improvement of sensor performance due to excellent interface property between enzyme and metal electrode for bio sensor manufacturing process.

• Bulletin of the Korean Mathematical Society
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• v.51 no.3
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• pp.813-822
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• 2014

A ring R is called quasipolar if for every a 2 R there exists $p^2=p{\in}R$ such that $p{\in}comm^2{_R}(a)$, $ a+p{\in}U(R)$ and $ap{\in}R^{qnil}$. The class of quasipolar rings lies properly between the class of strongly ${\pi}$-regular rings and the class of strongly clean rings. In this paper, we determine when a $2{\times}2$ matrix over a local ring is quasipolar. Necessary and sufficient conditions for a $2{\times}2$ matrix ring to be quasipolar are obtained.

• Journal of the Korean Society of Costume
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• v.29
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• pp.71-83
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• 1996

The purpose of this study was 1) to investi-gate the trends of sex-role attitudes of women and 2) to examine the relations between sex-role attitudes and Yin-yang characteristics in clothing design. The survey was conducted among 317 women in Seoul and Kyunggi province. The results were as follows: 1) Androgynious gender and masculine gen-der with sex-role attitudes are strongly ap-peared among the low-age university students and not-married group. 2) Yang characteristics with light and cool-warm color to the clothing color and with clothing design are strongly appeared ming the low-age university students and not-mar-ried group. 3) Masculine attitude with clothing design preference attitudes are strongly appeared among the low-ager university students and not-married group. Many persons appeared to have feminine attitude rather than in andro-gynious attitude. 4) There are significant differences between sex-role attitudes and yin-yang characteristics to the clothing design. A high level of mascu-line gender is storngly indicated the yang characteristics with saturation to the clothing colorand and with clothing design 5) There are significant differences between sex-role attitudes and clothing design prefer-ence attitudes.

• Korean Journal of Radiology
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• v.22 no.10
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• pp.1640-1649
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• 2021

Objective: Flattening in the anteroposterior direction (AP flattening) of the terminal ileum (TI) or sigmoid colon (SC) lying across the psoas muscle, on magnetic resonance enterography (MRE), might mimic bowel inflammation in the coronal view. This study investigated the prevalence of AP flattening and the factors associated with its development. Materials and Methods: A total of 364 surgery-naïve patients with Crohn's disease (CD) who had undergone MRE were retrospectively reviewed. AP flattening was defined as a luminal collapse in the anteroposterior direction, with a bowel width in the axial plane < 1/4 of the normal diameter without reduction of bowel width in coronal images. The prevalence of AP flattening of the TI and SC on MRE in patients with bowel segments lying across the psoas muscle was determined. We further compared the rate of AP flattening between MRE and computed tomography enterography (CTE) in a subcohort of patients with prior CTE. The factors associated with AP flattening were analyzed using multivariable logistic regression in a subcohort of patients with endoscopic findings of TI. Results: Three hundred and twenty-two and 363 patients, respectively, had TI and SC lying across the psoas muscle. The prevalence of AP flattening on MRE was 7.5% (24/322) in TI and 5.2% (19/363) in SC. The prevalences were significantly higher on MRE than on CTE in both the TI (7.3% [12/164] vs. 0.6% [1/164]; p = 0.003) and SC (5.8% [11/190] vs. 1.6% [3/190]; p = 0.039). AP flattening of the TI was independently and strongly associated with the absence of CD inflammation on endoscopy, with an adjusted odds ratio of 0.066 (p = 0.003) for the presence versus the absence (reference) of inflammation. Conclusion: AP flattening of the TI or SC lying across the psoas muscle was uncommon and predominantly observed on MRE of the bowel without CD inflammation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.12
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• pp.4269-4292
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• 2014

Currently, increasing numbers of access points (AP) are being deployed in enterprise offices, campuses and municipal downtowns for flexible Internet connectivity, but most of these access points are idle or redundant most of the time, which causes significant energy waste. Therefore, with respect to power conservation, applying energy efficient strategies in WIFI networks is strongly advocated. One feasible method is dynamically managing network resources, particularly APs, by powering devices on or off. However, when an AP is powered on, the device is initialized through a long boot time, during which period clients cannot be associated with it; therefore, the network performance would be greatly impacted. In this paper, based on a global view of an entire WLAN, we propose an AP selection technology, known as Temporary Access Selection (TAS). The criterion of TAS is a fusion metric consisting of two evaluation indexes which are based on throughput and battery life, respectively. TAS is both service and clients' preference specific through balancing the data rate, battery life and packet size. TAS also works well independently in traditional WLANs in which no energy efficient strategy is deployed. Moreover, this paper demonstrates the feasibility and performance of TAS through experiments and simulations with Network Simulator version 3 (NS3).

• Archives of Pharmacal Research
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• v.25 no.4
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• pp.475-479
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• 2002

Capsaicin, a major pungent constituent of red pepper (Capsicum annuum L.) possesses a vast variety of pharmacologic and physiologic activities. Despite its irritant properties, the compound exerts anti-inflammatory and anti-nociceptive effects. Previous studies from this laboratory revealed that capsaicin, when topically applied onto dorsal skin of female ICR mice, strongly attenuated activation of NF-kB and AP-1 induced by the typical tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), which may account for its anti-tumor promoting activity in mouse skin. In the present work, we have found that capsaicin suppresses TPA-stimulated activation of NF-kB through inhibition of $IkB{\alpha}$ degradation and blockade of subsequent nuclear translocation of p65 in human pro myelocytic leukemia HL-60 cells. Methylation of the phenolic hydroxyl group of capsaicin abolished its inhibitory effect on NF-kB DNA binding. Likewise, TPA-induced activation of AP-1 was mitigated by capsaicin treatment.

• The KIPS Transactions:PartC
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• v.18C no.1
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• pp.45-50
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• 2011

Due to advances in wireless communications and portable terminals, any-time, any-where, and any-device Internet access is possible. In particular, Internet access in moving vehicles is an emerging and challenging issue. Even though a variety studies have been conduced for vehicular networks, little attention is paid to vehicular Wi-Fi networks where a Wi-Fi access point (AP) is installed at the vehicle and the AP is connected to an external base station (BS). In this paper, we conduct a measurement study on the uplink and downlink throughput for Internet access in vehicular Wi-Fi networks. We consider diverse network environments: high-speed train, car, and subway. Measurement results demonstrate that current Internet access in vehicular Wi-Fi networks are not satisfactory for interactive multimedia applications. Therefore, in-depth study on resource management in vehicular Wi-Fi networks is strongly required.

• Toxicological Research
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• v.15 no.1
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• pp.109-115
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• 1999

The antiosidant activity of carnosine and related compounds such as anserine, homo-carnosine, histidine, and $\beta$-alanine which are found in most mammalian tissues, was investigated using hypochlorite (HOCl)-induced oxidant systems. Carnosine and related compounds were protective against HOCl-induced ascorbic acid oxidation, as determined by UV absorbance at 265nm. L-histidine was the most effective among them. The inhibitory effect of these compounds was strongly associated with a decrease in HOCl. It was also found that carnosine and related compounds significantly protected against the HOCl-mediated erythrocyte damage, as determined by hemoglobin release and gemolysis (p<0.05). Carnosine and anserine also inhibited of $\alpha$-antiprotease($\alpha$-AP) by HOCl, thereby inactivating porcine elastase. The inhibitory effect of carnosine on inactivation of $\alpha$-AP by HOCl depended on the concentration of carnosine and on the time preincubated with HOCl. Homocarnosine, histidine, and $\beta$-alanine did not inhibit the reaction. These results indicate that carnosine and related compounds can neutralize or scavenge HOCl. Thus, these compounds may play an important role in protecting against HOCl-mediated damage of biomolecules in vivo.

• Biomolecules & Therapeutics
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• v.25 no.2
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• pp.165-170
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• 2017

Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by $NF-{\kappa}B$ and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor $(TNF)-{\alpha}$. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.

• Journal of Ginseng Research
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• v.46 no.5
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• pp.690-699
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• 2022

Background: Few studies reported the therapeutic effect of Korean Red Ginseng (KRG) in lung inflammatory diseases. However, the anti-inflammatory role and underlying molecular in cadmium-induced lung injury have been poorly understood, directly linked to chronic lung diseases (CLDs): chronic obstructive pulmonary disease (COPD), cancer etc. Therefore, in this study we aim to investigate the therapeutic activities of water extract of KRG (KRG-WE) in mouse cadmium-induced lung injury model. Method: The anti-inflammatory roles and underlying mechanisms of KRG-WE were evaluated in vitro under cadmium-stimulated lung epithelial cells (A549) and HEK293T cell line and in vivo in cadmium-induced lung injury mouse model using semi-quantitative polymerase chain reaction (RT-PCR), quantitative real-time PCR (qPCR), luciferase assay, immunoblotting, and FACS. Results: KRG-WE strongly ameliorated the symptoms of CdSO4-induced lung injury in mice according to total cell number in bronchoalveolar lavage fluid (BALF) and severity scores as well as cytokine levels. KRG-WE significantly suppressed the upregulation of inflammatory signaling comprising mitogen-activated protein kinases (MAPK) and their upstream enzymes. In in vitro study, KRG-WE suppressed expression of interleukin (IL)-6, matrix metalloproteinase (MMP)-2, and IL-8 while promoting recovery in CdSO₄-treated A549 cells. Similarly, KRG-WE reduced phosphorylation of MAPK and c-Jun/c-Fos in cadmium-exposed A549 cells. Conclusion: KRG-WE was found to attenuate symptoms of cadmium-induced lung injury and reduce the expression of inflammatory genes by suppression of MAPK/AP-1-mediated pathway.