• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 추계학술대회 및 한일 식물생명공학 심포지엄
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• pp.191-191
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• 2005

• 한국안전학회지
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• 제16권4호
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• pp.7-13
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• 2001

Wire electrical discharge machining experiments in conducted to investigate characteristics of acoustic emission (AE) and electrical discharge energy due to current peak (I$_{p}$), pulse on time($\tau$/on/). The AE signals are obtained with a sensor attached to workpiece side. Machining states are identified with scanning electron microscopy and residual stress analyzer. It is demonstrated that the residual stress provide reliable informations about the machining states. Moreover, machining states can be detected successfully using both the residual stress and AE count rate.e.

• Journal of Photoscience
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• 제9권2호
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• pp.229-232
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• 2002

There are two distinct UV-responsive signaling pathways in UV-irradiated mammalian cells, i.e., the DNA damage-dependent and -independent pathways. The former occurs in nucleus and results in growth arrest and apoptosis via post-translational modification of p53. The latter is initiated by oxidative stress and/or by damages in cell membrane or cytoplasm, which activate signaling cascade through intracellular molecules including mitogen activated protein kinases (MAPK). In normal human fibroblastic cells, all of MAPK family members, extracellular signal-related kinases (ERK), c-Jun N-terminal kinases (JNK) and p38, were rapidly phosphorylated following UV-irradiation. ERK phosphorylation was suppressed by an inhibitor of receptor tyrosine kinases (RTK). As ERK usually responds to mitogenic stimuli from RTK ligands, UV-induced ERK phosphorylation may be linked to the proliferation of survived cells. In contrast, phosphorylation of JNK and p38, as well as apoptosis, were modulated by the level of UV-generated oxidative stress Therefore, JNK and p38 may take part in oxidative stress-mediated apoptosis. Phosphorylation of p53 at Ser and Thr residues are essential for stabilization and activation of p53. Among several sites reported, we confirmed phosphorylation at Ser-15 and Ser-392 after UV-irradiation. Both of these were inhibited by a phosphoinositide 3-kinase inhibitor, presumably due to the shutdown of signals from DNA damage to p53. Phosphorylation at Ser-392 was also sensitive to an antioxidant and a p38 inhibitor, suggesting that Ser-392 of p53 is one of the possible points where DNA damage-dependent and -independent apoptic signals merge. Thus, MAPK pathway links UV-induced intracellular signals to the nuclear responses and modifies DNA damage-dependent cellular outcome, resulting in the determination of cell death.

• 대한기계학회논문집A
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• 제29권6호
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• pp.822-827
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• 2005

The characteristics of elastic waves emanating from crack initiation and propagation in 6061 aluminum alloy subjected to fatigue loading with different stress ratio was investigated. The objective of this study is to determine the properties of the signals generated from each stage of fatigue crack growth. AS a crack propagates, substantial elastic wave occurred just prior to penetration. Then it decreased and the crack penetrated. The waveforms and their power spectra were found to be dependent on the different stress ratio associated with the signals. It is determined that high-frequency signal $0.5{\sim}0.75$ MHz is most likely emitted during crack propagation at peak load of fatigue cycle which release the highest energy. It is determined that 0.3 MHz is closely related to crack closure effect. The frequency peaks below 0.25 MHz may be attributed to fretting or hydraulic noise.

• 한국해양공학회지
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• 제15권1호
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• pp.52-56
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• 2001

This study were looks at the effect of the initial cut length or stress concentration level, on the wave forms produced by crack propagation. The signals were collected, then classified visually for each type of sample. They were put into three classes according to their shapes in the time and frequency domain. Each class should domain signals which could be correlated to a certain micro-failure mechanism that occurs during the fatigue process. Classes of these signals compared, with each sample. To see if there were any classes common to the three samples. The fatigue test attempted to determine if the initial cut length has any influence on the type of signals.

• Nutrition Research and Practice
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• 제9권3호
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• pp.235-241
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• 2015

BACKGROUND/OBJECTIVES: Doenjang, Korean traditional fermented soybean paste has been reported to have an anti-obesity effect. Because adipose tissue is considered a major source of inflammatory signals, we investigated the protective effects of Doenjang and steamed soybean on oxidative stress and inflammation in adipose tissue of diet-induced obese mice. MATERIALS/METHODS: Male C57BL/6J mice were fed a low fat diet (LF), a high-fat diet (HF), or a high-fat containing Doenjang diet (DJ) or a high-fat containing steamed soybean diet (SS) for 11 weeks. RESULTS: Mice fed a DJ diet showed significantly lower body and adipose tissue weights than those in the HF group. Although no significant differences in adipocyte size and number were observed among the HF diet-fed groups, consumption of Doenjang alleviated the incidence of crown-like structures in adipose tissue. Consistently, we observed significantly reduced mRNA levels of oxidative stress markers (heme oxygenase-1 and $p40^{phox}$), pro-inflammatory adipokines (tumor necrosis factor alpha and macrophage chemoattractant protein-1), macrophage markers (CD68 and CD11c), and a fibrosis marker (transforming growth factor beta 1) by Doenjang consumption. Gene expression of anti-inflammatory adipokine, adiponectin was significantly induced in the DJ group and the SS group compared to the HF group. The anti-oxidative stress and anti-inflammatory effects observed in mice fed an SS diet were not as effective as those in mice fed a DJ diet, suggesting that the bioactive compounds produced during fermentation and aging may be involved in the observed health-beneficial effects of Doenjang. CONCLUSIONS: Doenjang alleviated oxidative stress and restored the dysregulated expression of adipokine genes caused by excess adiposity. Therefore, Doenjang may ameliorate systemic inflammation and oxidative stress in obesity via inhibition of inflammatory signals of adipose tissue.

• Journal of Platform Technology
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• 제9권1호
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• pp.40-45
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• 2021

COVID-19 펜데믹으로 인하여 우리의 일상은 많은 변화를 가지고 왔다. 이로 인한 사회적거리두기와 같은 공중보건 조치로 인하여 COVID-19의 확장을 줄이는 데는 필수적이나, 동시에 우울증, 불안장애, 우울장애, 외상 및 스트레스 관련 장애 등에 노출이 되고 있다. 본 논문에서는 생체신호를 실시간으로 측정이 가능한 Smart Watch 디바이스를 기반으로 한 ECG와 PPG 측정을 통하여 HRV 데이터 및 스트레스 지수 확인이 가능한 Application을 개발하였다. 개발된 Application의 경우 실시간으로 Heart Rate를 측정하여 표시 하였으며, 걸음 수와 칼로리, 총 운동 거리를 측정하여 기본적인 운동정보를 전달하였고, 측정하기 프로그램으로 혈압, 심박수, HRV 데이터를 블루투스 기반으로 원활히 전달 하였다. 이를 통해 스스로 정신건강 관리를 할 수 있는 IoT 스마트 스트레스 케어 Application이 스트레스 및 우울 외상 장애 환자에게 도움이 될 것이라 생각한다.

• Corrosion Science and Technology
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• 제12권2호
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• pp.93-101
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• 2013

The object of this work is to establish an electrochemical noise(EN) measurement technique combined with a direct current potential drop(DCPD) method for monitoring of localized corrosion cracking of nickel-based alloy, and to analyze its mechanism. The electrochemical current and potential noises were measured under various conditions of applied stress to a compact tension specimen in a simulated primary water chemistry of a pressurized water reactor. The amplitude and frequency of the EN signals were evaluated in both time and frequency domains based on a shot noise theory, and then quantitatively analyzed using statistical Weibull distribution function. From the spectral analysis, the effect of the current application in DCPD was found to be effectively excluded from the EN signals generated from the localized corrosion cracking. With the aid of a microstructural analysis, the relationship between EN signals and the localized corrosion cracking mechanism was investigated by comparing the shape parameter of Weibull distribution of a mean time-to-failure.

• 설비공학논문집
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• 제27권11호
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• pp.596-602
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• 2015

In this study, experiments using bioelectronic signals and questionnaire surveys were carried out in learning conditions when temperatures changed from low- and high-uncomfortable to comfortable. As a result, the stress factor Photoplethysmography (PPG) decreased, while the Root Mean Square of Standard Deviation (RMSSD) of PPG increased when the indoor temperature was changed from low- or high-uncomfortable to comfortable. Additionally, the absolute power of the ${\alpha}$-wave in the brain increased. According to the analysis of the association between the questionnaire and bioelectronic signals, the standard deviation of the stress factor as measured by pulse was closely related to the result of the thermal sensation questionnaire. In addition, it was found that the concentration on studying improved under comfortable temperatures when compared to uncomfortable temperatures.

• 융합신호처리학회논문지
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• 제20권1호
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• pp.9-15
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• 2019

As the human population increases in the world, the ratio of health doctors is rapidly decreasing. Therefore, it is an urgent need to create new technologies to monitor the physical and mental health of people during their daily life. In particular, negative mental states like depression and anxiety are big problems in modern societies. Usually this happens due to stressful situations during everyday activities including work. This paper presents a machine learning approach to reliably estimating the level of human mental stress using wearable physiological sensors. And also, this paper presents an Android- and Arduino-based stress monitoring and relief system.