• Journal of Bio-Environment Control
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• v.32 no.4
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• pp.342-352
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• 2023

Ultra-violet (UV) light is one of abiotic stress factors and causes oxidative stress in plants, but a suitable level of UV radiation can be used to enhance the phytochemical content of plants. The accumulation of antioxidant phenolic compounds in UV-exposed plants may vary depending on the conditions of plant (species, cultivar, age, etc.) and UV (wavelength, energy, irradiation period, etc.). To date, however, little research has been conducted on how leaf thickness affects the pattern of phytochemical accumulation. In this study, we conducted an experiment to find out how the antioxidant phenolic content of kale (Brassica oleracea var. acephala) leaves with different thicknesses react to UV-A light. Kale seedlings were grown in a controlled growth chamber for four weeks under the following conditions: 20℃ temperature, 60% relative humidity, 12-hour photoperiod, light source (fluorescent lamp), and photosynthetic photon flux density of 121±10 µmol m^-2 s^-1. The kale plants were then transferred to two chambers with different CO₂ concentrations (382±3.2 and 1,027±11.7 µmol mol^-1), and grown for 10 days. After then, each group of kale plants were subjected to UV-A LED (275+285 nm at peak wavelength) light of 25.4 W m^-2 for 5 days. As a result, when kale plants with thickened leaves from treatment with high CO₂ were exposed to UV-A, they had lower UV sensitivity than thinner leaves. The Fv/Fm (maximum quantum yield on photosystem II) in the leaves of kale exposed to UV-A in a low-concentration CO₂ environment decreased abruptly and significantly immediately after UV treatment, but not in kale leaves exposed to UV-A in a high-concentration CO₂ environment. The accumulation pattern of total phenolic content, antioxidant capacity and individual phenolic compounds varied according to leaf thickness. In conclusion, this experiment suggests that the UV intensity should vary based on the leaf thickness (age etc.) during UV treatment for phytochemical enhancement.

• The Korean Journal of Nuclear Medicine
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• v.37 no.5
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• pp.278-287
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• 2003

Purpose: The performance of nitroglycerin-challenged Tc-99m-MIBI quantitative gated SPECT for the detection of viable myocardium was compared with rest/24-hour redistribution Tl-201 SPECT Materials and Methods: In 22 patients with coronary artery disease, rest Tl-20l/ dipyridamole stress Tc-99m-MIBI gated/24-hour redistribution Tl-201 SPECT were peformed, and gated SPECT was repeated on-site after sublingual administration of nitroglycerin (0.6 mg). Follow-up gated SPECT was done 3 months after coronary artery bypass graft surgery. For 20 segments per patient, perfusion at rest and 24-hour redistribution, and wall motion and thickening at baseline and nitroglycerin-challenged state were quantified. Quantitative viability markers were evaluated and compared;(1) rest thallium uptake, (2) thallium uptake on 24-hour redistribution SPECT, (3) systolic wall thickening at baseline, and (4) systolic wall thickening with nitroglycerin-challenge. Results: Among 100 revascularized dysfunctional segments, wall motion improved in 66 segments (66%) on follow-up gated myocardial SPECT after bypass surgery. On receiver operating characteristic (ROC) curve analysis, the sensitivity and specificity of rest and 24-hour delayed redistribution Tl-201 SPECT were 79%, 44% and 82%, 44%, respectively, at the optimal cutoff value of 50% of Tl-201 uptake. The sensitivity and specificity of systolic wall thickening at baseline and nitroglycerin-challenge were 49%, 50% and 64%, 65% at the optimal cutoff value of 15% of systolic wall thickening. Area under the ROC curve of nitroglycerin-challenged systolic wall thickening was significantly larger than that of baseline systolic wall thickening (p=0.004). Conclusion: Nitroglycerin-challenged quantitative gated Tc-99m-MIBI SPECT was a useful method for predicting functional recovery of dysfunctional myocardium.

• Korean Journal of Soil Science and Fertilizer
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• v.7 no.3
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• pp.163-175
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• 1974

Effects on yields, yield components and nutrient content of potassium depression for two or three weeks at various growth stages were investigated in rice (var. Jinheung) under sand culture system.(K 40 ppm 1973) 1. Analysis of variance showed significant difference among treatments of both two-week (at p=0.01) and three-week depression (at p=0.05) in yield. 2. Most sensitive stage to potassium depression on yield appeared two weeks until heading (42% yield decrease) and sensitivity decreased the growth stage is apart from heading either before or after. During 30 days after transplanting two-week potassium depression increased yield, but three-week depression decreased yield. Until about 30 days after heading depression caused poor yield. 3. Root potassium involves in harvest index, filled grain ratio and grain weight with significant correlation and considerably in spikelet per panicle while potassium in leaf sheath+culm involves considerably in spikelet per panicle and panicle per hill. Relative total dry matter weight was significantly correlated with panicle per hill, spikelet per panicle and K or K/Ca+Mg only in leaf sheath+culm. The indications are that root potassium contributes for building sink and efficiency of structure while potassium in leaf sheat+culm primarily for building source, productive structure. 4. Relative yield was significantly correlated with potassium content in root and leaf sheath+culm and with K/Ca+Mg and its ratio before and after depression in root indicating that potassium depression occurs greatly in root and that K/Ca+Mg might have more important role than K content alone under depression. 5. Optimum level of $K_2O$ appears around 3% in leaf blade. 4% in leaf sheath+culm and 1% in root under the assumption that below these level the same content has the same role in relation to yield during growth. The K/Ca+Mg appeares to be 2.5 in root and should not decrease throughout the growth stages. 6. The increase of sodium content in plant by K depression was highest, especially in leaf sheath during the most insensitive period to K depression suggesting that insensitivity may be attributed to partial replacement of Na for K. Partial replacement seems very little in sensitive stage (later stage) and sensitive organ (root).

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.1
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• pp.172-180
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• 2002

Polychlorinated biphenyls(PCBs) are large scale industrial chemicals which are using in diverse applications. The goal of this study was to determine if exposure to 2,2',5,5'-tetrachlorobiphenyl (PCB 52) leads to an increase in the production of active oxidants, and subsequently promotes apoptosis of neuronal SK-N-MC cells. Reactive oxygen species (ROS) formation was examined in SK-N-MC cells after treatment of PCB 52 by concentrations and incubation times, respectively. It showed that the rate of ROS production in the cells was increased in a does-dependent manner to 45 min, followed by a return towards control levels after 120 min treatment. We also examined the association of PCB-induced apoptosis with the modulation of biomakers of oxidative damage to lipids (malondialdehyde [MDA]) in SK-N-MC cells. Increased MDA was observed in a dose-dependent manner in groups treated with 10, 15, and 20 figJ me of PCB 52 for 24 h. After treatment of PCB 52, the cells did not show any significant change in the rate of Cu/Zn-superoxide dismutase (Cu/Zn-SOD) activity. Whereas, the cells had a two-fold greater rate of change in catalase activity at 20 ㎍/㎖ of PCB 52 for 24 h when compared to control group. Korean Ginseng is one of the most important crude drugs which has been used as a traditional Oriental medicine. We next investigated protective effect of extracts of ginseng on cytotoxicity induced by PCB 52 in SK-N-MC cells. Pretreatment of SK-N-MC cells with 25-200 μg/ml of ginseng were reduced cell death in a dose-dependent manner in PCB 52-treated cells. To examine the sensitivity of beta-catenin to ginseng, the protective effect of a range of ginseng concentrations was examined in SK-N-MC cells treated with PCB 52. The result demonstrated that ginseng efficiently blocked PCB 52 inducible beta-catenin proteolysis in a concentration dependent manner. The ROS formation was also measured in the presences of extract of ginseng and superoxide dismutase (inhibitor of oxygen free radical production). The both SOD (400 U/ml) and ginseng (200 μg/ml) significantly inhibited RDS generation in PCB 52-treated group.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.8
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• pp.975-981
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• 2013

A robust optimization is only one of the ways to minimize the effects of variances in design variables on the objective functions at the preliminary design stage. To predict the variances and to formulate the probabilistic constraints are the most important procedures for the robust optimization formulation. Though several methods such as the process capability index and the six sigma technique were proposed for the prediction and formulation of the variances and probabilistic constraints, respectively, there are few attempts using a percent defective which has been widely applied in the quality control of the manufacturing process for probabilistic constraints. In this study, the robust optimization for a lower control arm of automobile vehicle was carried out, in which the design space showing the mean and variance sensitivity of weight and stress was explored before robust optimization for a lower control arm. The 2nd order Taylor expansion for calculating the standard deviation was used to improve the numerical accuracy for predicting the variances. Simplex algorithm which does not use the gradient information in optimization was used to convert constrained optimization into unconstrained one in robust optimization.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.49 no.2
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• pp.1-8
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• 2012

This paper presents the accelerometer which is a key component of TPMS(Tire Pressure Monitoring System). Generally a piezoresistive accelerometer has characteristics of lower cost, better linearity and better immunity about the environmnet noise than a capacitive one. Three types of piezoresistive accelerometers are degined and simulated using ANSYS program. The best one is a piezoresistive sensor which is supported by four beams located at the center of the edge of the mass after comparing the characteristics of resonant frequency of the three types. Considering the sensor size and a simulated maximum stress and maximum displacement, the length of beams is set as $200{\mu}m$. The size of a piezoresistive accelerometer is $3.0mm{\times}3.0mm{\times}0.4mm$. The sensor output is characterized by measuring the output characteristic depending on angle. As a result the offset voltage of the accelerometer is 43.2 mV and its sensitivity is $42.5{\mu}V/V/g$. The temperature bias drift is measured. The shock durability of the sensor is 1500g and the measuring range is 0 ~ 60 g.

• Korean Journal of Community Nutrition
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• v.7 no.5
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• pp.675-685
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• 2002

A study was performed to develop as a screening tool, the Simple Evaluation Questionnaire for screening Overweight Dietary Patterns in people in their 20's. We used the data from the 20 to 29 year old subjects who participated in the three surveys: the health behavior survey, the dietary habit survey and the food intake survey - as part of the National Health and Nutrition Survey of 1998. The 1,493 adults were classified into two body fatness groups, that of normal (including the underweight) , and the overweight (including the obese) on the basis of their relative body weight (RBW). When comparing general variables between the two groups, significant differences (11 variables) were found in gender, sadness/depression state, stress level, age, number of diseases, age when overweightedness started, maximum body weight, sleep length, presently a smoker, everyday smoking habits, number of alcoholic drinks in the past month, and the number of alcoholic drinks when dunk, as well as snacking frequency and fatty food consumption. There were significant differences between the two groups in the three variables of daily soup/kuk, pan fried fish/meat/poultry and cooked fish paste/ham/dried squid in terms of cooked food intake, and 11 variables of food size, cooked rice, stews, vegetables and kimchi at breakfast, panfried foods and beverage/teas at lunch, cooked rice and stews (liquid) at dinner, cooked fish paste/ham/dried squid at snacks and cooked fishpaste/ham/dried squid at snack between lunch and dinner. In terms of raw food intake, we observed significant differences (8 variables) in daily food intake and grains, grains/vegetables/fishes (shellfish) at breakfast, meat at lunch and milt at snack after dinner. After developing questions with indicators and analyzing the indicators by logistic regression analysis using 34 variables, including these 33, plus eating-out frequency, we chose 10 questions for the simple evaluation of dietary patterns for the overweight category, in order to give each one point each. Among them we assigned an additional point to one question and two points to another question. The average scores of the overweight and normal groups, as shown by the questionnaire developed, were 5.97 $\pm$ 2.36 and 7.36 $\pm$ 2.21, respectively. A score of seven points was selected as the cut-off point. We examined the sensitivity, specificity and positive predictive value of the questionnaire to the results of 49.3%,75.4% and 68.8%, respectively. The total score categorized as an overweight dietary pattern was 30.2%.

• The Korean Journal of Physiology and Pharmacology
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• v.8 no.2
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• pp.89-94
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• 2004

The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a key area for the cardiovascular regulation, and the humoral regulation is mediated by a number of substances, including the angiotensin (Ang) II and vasopressin. Recent studies suggest that central interleukin-1 (IL-1) activates the sympathetic nervous system and produces hypertension. The present study was undertaken to elucidate whether IL-1 and Ang II interact in the regulation of cardiovascular responses to the stress of hemorrhage. Thus, Sprague-Dawley rats were anesthetized and both femoral arteries were cannulated for direct measurement of arterial pressure and heart rate (HR) and for inducing hemorrhage. A guide cannula was placed into the lateral ventricle for injection of IL-1 $(0.1,\;1,\;10,\;20\;ng/2\;{\mu}l)$ or Ang II $(600\;ng/10\;{\mu}l)$. A glass microelectrode was inserted into the RVLM to record the single unit spike potential. Barosensitive neurons were identified by an increased number of single unit spikes in RVLM following intravenous injection of nitroprusside. I.c.v. $IL-1\;{\beta}$ increased mean arterial pressure (MAP) in a dose-dependent fashion, but HR in a dose-independent pattern. The baroreceptor reflex sensitivity was not affected by i.c.v. $IL-1\;{\beta}$. Both i.c.v. $IL-1\;{\alpha}\;and\;{\beta}$ produced similar increase in MAP and HR. When hemorrhage was induced after i.c.v. injection of $IL-1\;{\beta}$, the magnitude of MAP fall was not different from the control. The $IL-1\;{\beta}$ group showed a smaller decrease in HR and a lower spike potential count in RVLM than the control. MAP fall in response to hemorrhage after i.c.v. injection of Ang II was not different from the control. When both IL-1 and Ang II were simultaneously injected i.c.v., however, MAP fall was significantly smaller than the control, and HR was increased rather than decreased. These data suggest that IL-1, a defense immune mediator, manifests a hypertensive action in the central nervous system and attenuates the hypotensive response to hemorrhage by interaction with Ang II.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.43 no.3 s.309
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• pp.60-66
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• 2006

The purpose of this study was to suggest a new detection method for early diagnosing diabetic neuropathic foot by obtaining a ratio of toe to finger blood flow using photoplethysmography(PPG) and Laser Doppler(LD). Nerve conduction velocity (NCV) has been routinely used for diagnosing neuropathic foot, but it applies strong electric stimulus to peripheries resulting in stress and pain. The blood flow ratio of 50 neuropathic diabetes($0.96{\pm}0.20$) was significantly higher than that of 64 normal person($0.46{\pm}0.15$)(p<0.000). It also showed that toe temperature of neuropathic diabetes($30.5{\pm}1.4^{\circ}C$) was significantly higher than that of normal group($29.3{\pm}2.0^{\circ}C$)(p<0.000). The optimal boundary value of the blood flow ratio was found to be 0.678 and the sensitivity and specificity of this proposed method resulted in 95.3% and 95.3% respectively. Lastly, there were no neuropathic diabetes whose temperature difference between finger and toe was higher than $4.5\;^{\circ}C$.

• International Journal of Highway Engineering
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• v.5 no.4 s.18
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• pp.1-11
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• 2003

Recently, the new pavement design method considering Korean environment and the specification for improving performance of pavement are being developed in Korea. The Jointed Concrete Pavement Program Applying Load Discretization Algorithm (called HEART-JCP) is one of the results of Korea Pavement Research Project in Korea. HEART-JCP program is developed to analyze various loading condition using the load discretization algorithm without mesh refinement. In addition, it can be modified easily into multi-purpose concrete pavement nidyses program because of the modularized structure characteristic of HEART-JCP. The program consists of basic program part and load discretization part. In basic program part, the displacement and stress are computed in the concrete slab, sub-layer, and dowel bar, which are modeled with plate/shell element, spring element and beam element. In load discretization program part, load discretization algorithm that was used for the continuum solid element is modified to analyze the model with plate and shell element. The program can analyze the distributed load, concentrated load, thermal load and body load using load discretization algorithm. From the result of verification and sensitivity study, it was known that the loading position, the magnitude of load, and the thickness of slab were the major factors of concrete pavement behavior as expected. Since the result of the model developed is similar to the results of Westergaard solution and ILLISLAB, the program can be used to estimate the behavior of jointed concrete pavement reasonably.