• Title/Summary/Keyword: stress sensitivity

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Some aspects of load-rate sensitivity in visco-elastic microplane material model

  • Kozar, Ivica;Ozbolt, Josko
    • Computers and Concrete
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    • v.7 no.4
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    • pp.317-329
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    • 2010
  • The paper describes localization of deformation in a bar under tensile loading. The material of the bar is considered as non-linear viscous elastic and the bar consists of two symmetric halves. It is assumed that the model represents behavior of the quasi-brittle viscous material under uniaxial tension with different loading rates. Besides that, the bar could represent uniaxial stress-strain law on a single plane of a microplane material model. Non-linear material property is taken from the microplane material model and it is coupled with the viscous damper producing non-linear Maxwell material model. Mathematically, the problem is described with a system of two partial differential equations with a non-linear algebraic constraint. In order to obtain solution, the system of differential algebraic equations is transformed into a system of three partial differential equations. System is subjected to loadings of different rate and it is shown that localization occurs only for high loading rates. Mathematically, in such a case two solutions are possible: one without the localization (unstable) and one with the localization (stable one). Furthermore, mass is added to the bar and in that case the problem is described with a system of four differential equations. It is demonstrated that for high enough loading rates, it is the added mass that dominates the response, in contrast to the viscous and elastic material parameters that dominated in the case without mass. This is demonstrated by several numerical examples.

Behavioral Response and Immune Alterations by Electric Footshock in Mice (생쥐에서 전기자극 스트레스에 의한 행동반응과 면역 기능 변화)

  • Kim, Jung-Bum;Park, Won-Kyun;Song, Dae-Kyu
    • Korean Journal of Psychosomatic Medicine
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    • v.4 no.1
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    • pp.44-53
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    • 1996
  • The present experiment was designed to investigate the effects of behavioral, response to immune function in response to electric footshock in mice. Mice were subjected to electric footshock for 3 days(two sessions a day, 11 times of shock for about 31 minutes a session). The humoral immune response was measured using mice immunized with rat RBC. The cell-mediated immune responses were evaluated by contact hypersensitivity to 2, 4-dinitrofluorobenzene(DNFB) and by phytohemagglutin(PHA)-stimulated splenocytes proliferation assay. In stressed group, electric footshock suppressed significantly anti-rat RBC antibody production(p<0.05), but enhanced significantly $T_{48}$ relative to $T_{24}$ in contact hypersenstivry (P<.01) and T-cell proliferation response(P<.05) by PHA stimulation elative to control group. T-cell proliferation response by PHA stimulation was significantly correlated to the movement than the sensitivity and coping behavior in the mouse, in response to the electric footshock. These data supper the importance of behavioral response in stress-induced changes of immune functions.

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Knockdown of RCAN1.4 Increases Susceptibility to FAS-mediated and DNA-damage-induced Apoptosis by Upregulation of p53 Expression

  • Kim, Young-Sun;Lee, Hong-Joon;Jang, Cho-Rong;Kim, Ho-Shik;Cho, Young-Jin
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.6
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    • pp.483-489
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    • 2009
  • Despite the potential importance of the human regulator of calcineurin 1 (RCAN-1) gene in the modulation of cell survival under stress, little is known about its role in death-inducing signal pathways. In this study, we addressed the effects of RCAN1.4 knockdown on cellular susceptibility to apoptosis and the activation of death pathway proteins. Transfection of siRNAs against RCAN1.4 resulted in enhanced Fas- and etoposide-induced apoptosis, which was associated with increased expression and translocation of Bax to mitochondria. Our results suggest that enhanced expression and activation of p53 was responsible for the upregulation of Bax and the increased sensitivity to apoptosis, which could be reversed by p53 knockdown. To explain the observed upregulation of p53, we propose a downregulation of the ubiquitin ligase HDM2, probably translationally. These findings show the importance of appropriate RCAN1.4 expression in the modulation of cell survival and reveal a link between RCAN1.4 and p53.

Influence of Thermal Treatment on Surface Morphology of Tin Dioxide Thin Films (열처리에 따른 SnO2 박막의 표면형상)

  • Park, Kyung-Hee;Ryu, Hyun-Wook;Seo, Yong-Jin;Lee, Woo-Sun;Hong, Kwang-Jun;Park, Jin-Seong
    • Korean Journal of Materials Research
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    • v.13 no.7
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    • pp.442-446
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    • 2003
  • Tin dioxide ($SnO _2$) thin films were deposited at $375^{\circ}C$ on alumina substrate by metal-organic chemical vapor deposition. A few hillocks like a cauliflower were observed and the number of hillock on thin film surface increased with annealing temperature in air atmosphere. The oxygen content and the binding energy during air annealing at$ 500^{\circ}C$ came to close the stoichiometric $SnO_2$. The cauliflower hillocks seem to be the result of the continuous migration of the tiny grains to release the stress of an expanded grain. Sensitivity of CO gas depended on annealing temperature and increased with increasing annealing temperature.

PREDICTION OF MICROSTRUCTURE DURING HIGH TEMPERATURE FORMING OF Ti-6Al-4V ALLOY

  • Lee Y. H.;Shin T. J.;Yeom J. T.;Park N. K.;Hong S. S.;Shim I. O.;Hwang S. M.;Lee C. S.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2003.10b
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    • pp.43-46
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    • 2003
  • Prediction of final microstructures after high temperature forming of Ti-6Al-4V alloy was attempted in this study. Using two typical microstructures, i.e., equiaxed and $Widmanst\ddot{a}tten$ microstructures, compression test was carried out up to the strain level of 0.6 at various temperatures $(700\~1100^{\circ}C)$ and strain rates $(10^{-4}\~10^2/s)$. From the flow stress-strain data, parameters such as strain rate sensitivity (m) and activation energy (Q) were calculated and used to establish constitutive equations for both microstructures. Then, finite element analysis was performed to predict the final microstructure of the deformed body, which was well accorded with the experimental results.

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The Parameters of the Bounding Surface Plasticity Model in the Isotropically Consolidated Clay (등방압밀점토에서 항복경계면 소성모델의 매개변수)

  • 이영생;김원영
    • Geotechnical Engineering
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    • v.12 no.4
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    • pp.21-32
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    • 1996
  • To predict the stress-strain behavior of the soil more approximately, the concept of the critical state soil mechanics was added to the plasticity increment theory in the bounding surface Plasticity model. This model was constituted with two ellipse and one hyperbola in older to describe the behaviour of the isotropically consolidated soil. Thus, this model is very complicate due to the various parameters used. Therefore, the accurate understanding and skill of the theory is required in order to apply this model to the practical geotechnical problems. In the present paper, the bounding surface shape paraiheter R and A, the mapping center parameter C among various parameters used were varied and the results were numerically analized. Finally, each sensitivity with respect to monotonic and cyclic loading was analized and the range of the value of the each parameter was proposed.

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Design of High Speed Spindle for 5-Axis Machining Equipment Equipped with Piezo-Electric Load Sensoring (압전형 부하 센서링이 장착된 5축 절삭가공기의 고속 주축시스템 설계)

  • Choi, Hyun-Jin;Park, Chul-Woo;Jang, Eun-Sil;Kim, Chung-Hyun;Choi, Seong-Dae
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.10 no.5
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    • pp.20-25
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    • 2011
  • In this paper, we reviewed the spindle system's motor and bearing and its mode safety for optimal design of a high speed spindle system that exceeds DmN value of 1,500,000. We could verify that it has a separation margin during critical speed by performing critical speed analysis. Also, we have selected an optimal sensoring installation location and actually manufactured & installed the sensor by identifying the stress concentration position in the axial load through finite element analysis to install the built-in piezo electric type load sensor to the spindle housing that can measure and monitor the machining load during high speed rotation of the spindle. Reproducibility is also verified by calibrating the error through the sensor's sensitivity adjustment after comparing the output between the plate dynamoneters and the load sensor to confirm the reproducibility of the load sensor.

Optimum Structural Design of a Triaxial Load Cell for Wind Tunnel Test (풍동용 3 축 로드셀의 구조최적설계)

  • Lee, Jae-Hoon;Song, Chang-Kon;Park, Seong-Hun
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.2
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    • pp.226-232
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    • 2011
  • In this study, an optimized design of a triaxial load cell has been developed by the use of finite element analysis, design of experiment and response surface method. The developed optimal design was further validated by both stress-strain analysis and natural vibration analysis under an applied load of 30 kgf. When vertical, horizontal, and axial loads of 30 kgf were applied to the load cell with the optimal design, the calculated strains were satisfied with the required strain range of $500{\times}10^{-6}{\pm}10%$. The natural vibration analysis exhibited that the fundamental natural frequency of the optimally designed load cell was 5.56 kHz and higher enough than a maximum frequency of 0.17 kHz which can be applied to the load cell for wind-tunnel tests. The satisfactory sensitivity in all triaxial directions also suggests that the currently proposed design of the triaxial load cell enables accurate measurements of the multi-axial forces in wind-tunnel tests.

Sensitivity Analysis of the Factors Influencing for Decision of Reinforced Roadbed Thickness (강화노반 두께 결정을 위한 영향인자 민감도 분석)

  • Choi, Chan-Yong;Lee, Jin-Wook;Bae, Jae-Hoon;Shin, Eun-Chul
    • Proceedings of the KSR Conference
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    • 2007.05a
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    • pp.1827-1832
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    • 2007
  • The purpose of a railway track is to provide a smooth surface for safe and economical train transportation. The performance of the track results from a complex interaction of the track and subgrade components in response to train loading and environmental actions. In the past, the role of subgrade as the track foundation were not recognized adequately. There are insufficient information and inadequate methods for subgrade design, assessment and improvement. This situation has survived for a long time largely because a subgrade defect can often be adjusted by adding more ballast under the ties or applying more frequent track maintenance. Therefore, the application of reinforced roadbed technology will be expected to increase in the future. The reinforced roadbed thickness is set depending on subgrade reaction modulus$(K_{30})$ in the condition of upper subgrade through PBT in both conventional railroad and KTX railroads. As train velocity (V), train passing tonnage (N), and train axial load (P) are not considered in design, the roadbed thickness could be overestimated (or underestimated). Therefore, In this study, the computer model, GEOTRACK, was analyzed the influence of reinforced roadbed thickness factors on track modulus and the characteristics of stress pulses in track and subgrade generated by repeated axle loading.

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Effect of Process Parameters of P/M and Induction Heating on the Cell Morphology and Mechanical Properties of 6061 Aluminum Alloy (P/M법과 유도가열 공정변수가 6061 알루미늄 합금의 미세기공과 기계적 성질에 미치는 영향)

  • 강충길;윤성원
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.6
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    • pp.222-229
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    • 2003
  • The purpose of this study is to evaluate the mechanical properties of 6061 Al foams, which were fabricated by P/M and multi-step induction heating method, and to build the database, which is needed for computer aided modeling or foam components design. Aluminium foams, consisting of solid aluminium and large quantities of porosities, is widely used in automotive, aerospace, naval as well as functional applications because of its high stiffness at very low density, high impact energy absorption, heat and fire resistance, and greater thermal stability than any organic material. In this study, 6061 Al foams were fabricated for variation of fraction of porosities (%) according to porosities (%)-final heating temperature ( $T_{a3}$) curves. Mechanical properties such as compressive strength, energy absorption capacity, and efficiency were investigated to evaluate the feasibility of foams as crash energy absorbing components. Moreover, effect of the surface skin thickness on plateau stress and strain sensitivity of the 6061 Al foams with low porosities (%) were studied.d.