• Title/Summary/Keyword: stress failure

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Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial

  • Yang, Yi;Wang, Hong;Zhang, Ming;Shi, Mengxue;Yang, Cailing;Ni, Qiang;Wang, Qi;Li, Jing;Wang, Xuemei;Zhang, Chen;Li, Zhi
    • Journal of Ginseng Research
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    • v.46 no.4
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    • pp.543-549
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    • 2022
  • Background: In physical activity or labor, the human body is in a state of high intensity stress, and all parts or physiological functions of the body respond positively to maintain or balance the need for movement. The human body has many physiological changes in the process of movement, and fatigue is the external manifestation of various complex changes inside the human body. Fatigue is also a physiological mechanism of self-protection after the body reaches a certain level of activity, which can prevent the occurrence of life-threatening excessive functional failure. The generation of fatigue is a very complex process, and its mechanism has not been concluded yet. Therefore, it is an important work to search and screen the effective components of natural plants that have anti-fatigue effect and to explore their mechanism. Methods: This was a 8-week, randomized, double-blind, placebo-controlled clinical trial. A total of 110 subjects who passed physical examination were included according to the scheme design, and randomly divided into a test group which was given KRG and a placebo control group. The calculation is carried out according to the standard of sub-high-intensity exercise test. Results: There was no adverse effect on safety index of subjects after taking red ginseng capsule. After KRG treatment, subjective strength grade is significant lower than placebo treatment. Blood lactic acid content is significantly get lower after trial in KRG group, and significant lower than placebo group. Creatine phosphokinase(CK) content is significantly get lower after trial in KRG group, and significant lower than placebo group. Conclusion: According to the criterion in the test scheme, the result shows that KRG is helpful on relieving physical fatigue.

Structural and Dynamic Analysis of a Unmanned Cargo Multicopter Using Hybrid Power System (하이브리드 추진 시스템을 이용한 수송용 멀티콥터 무인기의 구조 및 동특성 해석)

  • Kee, Youngjung;Kim, Taekyun
    • Journal of Aerospace System Engineering
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    • v.16 no.5
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    • pp.78-85
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    • 2022
  • Multicopter-type unmanned aerial vehicles (UAV) are increasingly for cargo transportation to mountainous and island regions, image information acquisition in disaster areas, and emergency rescue transport. In order to successfully perform these tasks, the aircraft structure must be able to safely support the loads induced by flight conditions while ensuring the vibration and aeroelastic stability of the prop-rotor. This study introduced a structural analysis model of a 40kg payload multicopter with an engine-generator hybrid power system. The deformation and stress distribution are investigated depending on the load conditions. In addition, the vibration characteristics and aeroelastic stability of the prop-rotor were also presented to flight speed and aircraft pitch angle. The maximum thrust generated by the prop-rotor and the landing load applied to the multicopter under normal and emergency landing conditions were reviewed., It confirmed that the structure could support without failure. In addition, it confirmed that the damping characteristics of each primary locate in the constant region according to the aircraft's flight speed and the prop-rotors rotating speed.

Numerical FEM assessment of soil-pile system in liquefiable soil under earthquake loading including soil-pile interaction

  • Ebadi-Jamkhaneh, Mehdi;Homaioon-Ebrahimi, Amir;Kontoni, Denise-Penelope N.;Shokri-Amiri, Maedeh
    • Geomechanics and Engineering
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    • v.27 no.5
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    • pp.465-479
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    • 2021
  • One of the important causes of building and infrastructure failure, such as bridges on pile foundations, is the placement of the piles in liquefiable soil that can become unstable under seismic loads. Therefore, the overarching aim of this study is to investigate the seismic behavior of a soil-pile system in liquefiable soil using three-dimensional numerical FEM analysis, including soil-pile interaction. Effective parameters on concrete pile response, involving the pile diameter, pile length, soil type, and base acceleration, were considered in the framework of finite element non-linear dynamic analysis. The constitutive model of soil was considered as elasto-plastic kinematic-isotropic hardening. First, the finite element model was verified by comparing the variations on the pile response with the measured data from the centrifuge tests, and there was a strong agreement between the numerical and experimental results. Totally 64 non-linear time-history analyses were conducted, and the responses were investigated in terms of the lateral displacement of the pile, the effect of the base acceleration in the pile behavior, the bending moment distribution in the pile body, and the pore pressure. The numerical analysis results demonstrated that the relationship between the pile lateral displacement and the maximum base acceleration is non-linear. Furthermore, increasing the pile diameter results in an increase in the passive pressure of the soil. Also, piles with small and big diameters are subjected to yielding under bending and shear states, respectively. It is concluded that an effective stress-based ground response analysis should be conducted when there is a liquefaction condition in order to determine the maximum bending moment and shear force generated within the pile.

The effect of fiber reinforcement on behavior of Concrete-Filled Steel Tube Section (CFST) under transverse impact: Experimentally and numerically

  • Yaman, Zeynep
    • Structural Engineering and Mechanics
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    • v.82 no.2
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    • pp.173-189
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    • 2022
  • This study presents an experimental and numerically study about the effects of fiber reinforcement ratio on the behavior of concrete-filled steel tubes (CFST) under dynamic impact loading. In literature have examined the behavior of GFRP and FRP wrapped strengthened CFST elements impact loads. However, since the direction of potential impact force isn't too exact, there is always the probability of not being matched the impact force of the area where the reinforced. Therefore, instead of the fiber textile wrapping method which strengthens only a particular area of CFST element, we used fiber-added concrete-filled elements which allow strengthening the whole element. Thus, the effect of fiber-addition in concrete on the behavior of CFST elements under impact loads was examined. To do so, six simply supported CFST beams were constructed with none fiber, 2% fiber and 10% fiber reinforcement ratio on the concrete part of the CFST beam. CFST beams were examined under two different impact loads (75 kg and 225 kg). The impactors hit the beam from a 2000 mm free fall during the experimental study. Numerical models of the specimens were created using ABAQUS finite element software and validated with experimental data. The obtained results such as; mid-span displacement, acceleration, failure modes and energies from experimental and numerical studies were compared and discussed. Furthermore, the Von Misses stress distribution of the CFST beams with different ratio of fiber reinforcements were investigated numerically. To sum up, there is an optimum amount limit of the fiber reinforcement on CFST beams. Up to this limit, the fiber reinforcement increases the structural performances of the beam, beyond that limit the fiber reinforcement decreases the performances of the CFST beam under transverse impact loadings.

Experimental and numerical studies of concrete bridge decks using ultra high-performance concrete and reinforced concrete

  • Shemirani, Alireza Bagher
    • Computers and Concrete
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    • v.29 no.6
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    • pp.407-418
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    • 2022
  • This paper numerically investigates the effect of changes in the mechanical properties (displacement, strain, and stress) of the ultra-high-performance concrete (UHPC) without rebar and the reinforced concrete (RC) using steel re-bars. This reinforced concrete is mostly used in the concrete bridge decks. A mixture of sand, gravel, cement, water, steel fiber, superplasticizer, and micro silica was used to fabricate UHPC specimens. The extended finite element method as used in the ABAQUS software is applied for considering the mechanical properties of UHPC, RC, and ordinary concrete specimens. To calibrate the ABAQUS, some experimental tests have been carried out in the laboratory to measure the direct tensile strength of UHPC by the compressive-to-tensile load converting (CTLC) device. This device contains a concrete specimen and is mounted on a universal tensile testing apparatus. In the experiments, three types of mixed concrete were used for UHPC specimens. The tensile strength of these specimens ranges from 9.24 to 11.4 MPa, which is relatively high compared with ordinary concrete specimens, which have a tensile strength ranging from 2 to 5 MPa. In the experimental tests, the UHPC specimen of size 150×60×190 mm with a central hole of 75 mm (in diameter)×60 mm (in thickness) was specially made in the laboratory, and its direct tensile strength was measured by the CTLC device. However, the numerical simulation results for the tensile strength and failure mechanism of the UHPC were very close to those measured experimentally. From comparing the numerical and experimental results obtained in this study, it has been concluded that UHPC can be effectively used for bridge decks.

Theoretical Heat Flow Analysis and Vibration Characteristics During Transportation of PCS(Power Conversion System) for Reliability (전력변환장치 캐비넷에서의 내부발열 개선을 위한 열유동 분석 및 유통안전성 향상을 위한 진동특성 분석)

  • Joo, Minjung;Suh, Sang Uk;Oh, Jae Young;Jung, Hyun-Mo;Park, Jong-Min
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.28 no.2
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    • pp.143-149
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    • 2022
  • PCS needs to freely switch AC and DC to connect the battery, external AC loads and renewable energy in both directions for energy efficiency. Whenever converting happens, power loss inevitably occurs. Minimization of the power loss to save electricity and convert it for usage is a very critical function in PCS. PCS plays an important role in the ESS(Energy Storage System) but the importance of stabilizing semiconductors on PCB(Printed Circuit Board) should be empathized with a risk of failure such as a fire explosion. In this study, the temperature variation inside PCS was reviewed by cooling fan on top of PCS, and the vibration characteristics of PCS were analyzed during truck transportation for reliability of the product. In most cases, a cooling fan is mounted to control the inner temperature at the upper part of the PCS and components generating the heat placed on the internal aluminum cooling plate to apply the primary cooling and the secondary cooling system with inlet fans for the external air. Results of CFD showed slightly lack of circulating capacity but simulated temperatures were durable for components. The resonance points of PCS were various due to the complexity of components. Although they were less than 40 Hz which mostly occurs breakage, it was analyzed that the vibration displacement in the resonance frequency band was very insufficient. As a result of random-vibration simulation, the lower part was analyzed as the stress-concentrated point but no breakage was shown. The steel sheet could be stable for now, but for long-term domestic transportation, structural coupling may occur due to accumulation of fatigue strength. After the test completed, output voltage of the product had lost so that extra packaging such as bubble wrap should be considered.

Benzoylaconine improves mitochondrial function in oxygen-glucose deprivation and reperfusion-induced cardiomyocyte injury by activation of the AMPK/PGC-1 axis

  • Chen, Leijie;Yan, Laixing;Zhang, Weiwei
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.5
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    • pp.325-333
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    • 2022
  • Heart failure (HF) has become one of the severe public health problems. The detailed role of mitochondrial function in HF was still unclear. Benzoylaconine (BAC) is a traditional Chinese medicine, but its role in HF still needs to be explored. In this study, oxygen-glucose deprivation and reperfusion (OGD/R) was executed to mimic the injury of H9C2 cells in HF. The viability of H9C2 cells was assessed via MTT assay. OGD/R treatment markedly decreased the viability of H9C2 cells, but BAC treatment evidently increased the viability of OGD/R-treated H9C2 cells. The apoptosis of H9C2 was enhanced by OGD/R treatment but suppressed by BAC treatment. The mitochondrial membrane potential was evaluated via JC-1 assay. BAC improved the mitochondrial function and suppressed oxidative stress in OGD/R-treated H9C2 cells. Moreover, Western blot analysis revealed that the protein expression of p-AMPK and PGC-1α were reduced in OGD/R-treated H9C2 cells, which was reversed by BAC. Rescue assays indicated that AMPK attenuation reversed the BAC-mediated protective effect on OGD/R-treated cardiomyocytes. Moreover, BAC alleviated myocardial injury in vivo. In a word, BAC modulated the mitochondrial function in OGD/R-induced cardiomyocyte injury by activation of the AMPK/PGC-1 axis. The findings might provide support for the application of BAC in the treatment of HF.

Multimetric Measurement Data Monitoring System Using Sigmoid Function (시그모이드 함수를 이용한 다중 계측데이터 모니터링 시스템)

  • Jeong-Ho Song;Jun-Woo Shin;Heui-Soo Han
    • The Journal of Engineering Geology
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    • v.33 no.1
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    • pp.137-149
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    • 2023
  • In order to intuitively grasp the earth pressure direction acting on the structure and displacement state, displacement data in the horizontal and vertical directions were processed using the sigmoid function. A displacement coordinate system was set up for each axis. The system can intuitively check the current displacement and assess the management stage of each point. A displacement path can be compiled from continuously recorded points, allowing trends in the displacement's history and stress direction to be known. Analysis of data measured for excavated ground, found that displacement occurred in the direction of destressing at all points, and that the points' management state steady. Similar behavior trends were found among measurement points with high spatial correlation, whereas differing behavior trends occurred among measurement points with low spatial correlation. If the correlation analysis of the precursor and behavior area is performed using the continuously distributed surface settlement data and displacement coordinate system, it will be possible to predict the failure time and area.

A Comparison of the Crack Plane Equilibrium Model for Elastic-Plastic Fracture Analysis with the Irwin's Plastic Zone Corrected LEFM (탄소성 파괴해석을 위한 크랙 평면 평형모형과 항복 선형 파괴역학과의 비교에 관한 연구)

  • Lee, Kyu-Yong;Smith, F.W.
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.20 no.1
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    • pp.30-36
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    • 1984
  • It is well known that the application of linear elastic fracture mechanics is inadequate to solve the large deformation fracture failures which occurr in ductile manner because of the large scale yielding due to the severe stress concentration in the region adjacent to the crack tip. The authors have been evolved a fracture model, the crack plane equilibrium model, for this kinds of elastic-plastic fracture problems in the previous report. In this report, the crack plane equilibrium model was compared with the Irwin's plastic zone corrected linear elastic fracture mechanics through theoretical comparisons and experimental results to examine the validity of the crack plane equilibrium model as an available tool for nonlinear fracture analysis. Through this study, the main results were reached as follows; Irwin's plastic zone corrected linear elastic fracture mechanics could be applicable only for small scale yielding problems as expected while the crack plane equilibrium model valid as a fracture model for large deformation fracture failure. However, the followings should be considered for the more precise evaluations of CPE model; 1) It is necessary to test more specimens which contain small cracks in the range of 2a/W<0.1. 2) It is important to detect the crack initiation point during the fracture test for determining an accurate fracture load. 3) Effects of specimen thickness in the fracture process zone should be examined.

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Characteristics of Shear Behavior for Coarse Grained Materials Based on Large Scale Direct Shear Test (III) - Final Comprehensive Analysis - (대형직접전단시험을 이용한 조립재료의 전단거동 특성 (III) - 최종 종합 분석 -)

  • Lee, Dae-Soo;Kim, Kyoung-Yul;Hong, Sung-Yun;Oh, Gi-Dae;Jeong, Sang-Seom
    • Journal of the Korean Geotechnical Society
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    • v.25 no.4
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    • pp.39-54
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    • 2009
  • Large scale direct shear tests were carried out to analyze the shear behavior of crushed rocks at local representative quarries. Shear strength for each specimen was derived and the effects on shear behavior induced by the variation of factors such as particle size, water immersion, density, uniformity coefficient, and particle breakage were evaluated and quantitatively compared with previous studies. The opportunity was also taken to identify stress-dilatancy relation of crushed rocks following the energy-based theory and friction coefficients at critical state as well as peak friction angles and dilation angles were estimated. As a result of tests it was found that uniaxial compressive strength and particle breakage of the parent rocks have crucial effect on internal friction angles; in addition, dilatancy at the failure showed strong relationship as well.