• Structural Engineering and Mechanics
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• v.10 no.4
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• pp.299-312
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• 2000

The response of an embedded body to dynamic loads is greatly influenced by the reactions of the soil to the motion of the body. The properties of the soil surrounding embedded bodies (e.g., piles) may be different than those of the far-field for a variety of reasons. It may be weakened or strengthened according to the method of installation of piles, or altered due to applying one of the soil strengthening technique (e.g., electrokinetic treatment of soil, El Naggar et al. 1998). In all these cases, the shear strength of the soils and its shear modulus vary gradually in the radial direction, resulting in a radially inhomogeneous soil layer. This paper describes an analysis to compute vertical and torsional dynamic soil reactions of a radially inhomogeneous soil layer with a circular hole. These soil reactions could then be used to model the soil resistance in the analysis of the pile vibration under dynamic loads. The soil layer is considered to have a piecewise, radial variation for the complex shear modulus. The model is developed for soil layers improved using the electrokinetic technique but can be used for other situations where the soil properties vary gradually in the radial direction (strengthened or weakened). The soil reactions (impedance functions) are evaluated over a wide range of parameters and compared with those obtained from other solutions. A parametric study was performed to examine the effect of different soil improvement parameters on vertical and torsional impedance functions of the soil. The effect of the increase in the shear modulus and the width of the improved zone is investigated.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.831-839
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• 2002

Allergy has a born predominant cause of atopy in body and react oversenstively several meterial. The cause of allergy are tick, house dust, egg, milk, bean, cosmetics, virus, bacteria, flesh and meat in Western medicine. While, Oriental medicine did not have an application on the allergy, but recognized that allergy is connected with fetal toxicosis, heat-syndrome in new born, syndrome characterized by dyspnea, sneezing, stuffy nose, nasal discharge and phlegm. Therefor, We knowed method of medical treatment following cause of disease and pathogenesis against allergy. Allergic disease(atopic dermatitis, bronchial asthma, rhinitis) were related with lung, spleen, kidney. To prevent allergic disease in born, Oriental medicine taked a serious view of fetal education. In Western medicine, The cause of allergy applied to exopathogen of Oriental medicine. In Oriental medicine, Treatment of allergy used generally strengthening the body resistance to eliminate pathogenic factors.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.2
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• pp.141-153
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• 2024

Purpose : This study aimed to determine the effects of a 12-week program of beta-glucan intake and muscle strengthening exercises on the body composition, physical fitness, blood lipids, insulin and insulin resistance of adult women. Methods : For this study, 45 adult women were selected and divided into two groups : the experimental group (n= 25), which received a combination of beta-glucan and strength exercise, and the control group (n= 20), which received only strength exercise. The program was conducted for 50 minutes three times a week for 12 weeks. Results : Several significant differences were found in both groups pre-to post program. First, in both groups, there were significant differences in hip circumferences (p<.05). Second, the results showed significant improvements in left grip strength and sit-ups achieved (p<.05), right grip strength (p<.001). Third although the results show no significant post-program differences in either group, there was a significant pre-to post-program difference in free fatty acids in both groups (p<.05). Fourth, the results show no significant differences in insulin or insulin resistance in either group, nor do they show any significant differences between the groups. Conclusion : The above results indicate that both groups exhibited decreased hip circumference and increased muscle strength (left grip strength) and muscle endurance. Furthermore, they indicate that when the beta-glucan intake and exercises were combined, the effects were more pronounced. Finally, because both groups exhibited significant increases in fat-free mass, muscle mass, skeletal muscle mass, muscle strength (right grip strength), and coordination as well as decreases in free fatty acids, it can be concluded that both the combined program of beta-glucan intake and exercise and a program of exercise alone can positively affect these outcomes.

• Herbal Formula Science
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• v.5 no.1
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• pp.184-202
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• 1997

The results of immune response and antiallergic reaction were as follows. 1. Hemagglutinin titer and hemolysin titer were increased in case of AMR, AR, SNH. But the results were not recognized as having significance. 2. PFC was increased in case of AMR, AR. But the results were not recognized as having significance. 3. RFC was increased in all groups, and the results in the AR, SNH were significant. 4. In experimentation of phagocytic activity in peritoneal exudate cells, AR and SNH showed significant increase. In spleen cells AR and SNH showed significant increase. In monolymphocytus cells AMR, AR and SNH were increased, but result of AMR was of no significance. 5. I examined promotion on spleen cells transformation. As these results, AMR showed increase in $50{\mu}g/m{\ell}$, $5000{\mu}g/m{\ell}$ in comparison with control group. And in $500{\mu}g/m{\ell}$ AMR showed increase in case of 24 hours, 72 hours incubation, but showed decrease in case of 48 hours incubation. AR showed increase in all. In $50{\mu}g/m{\ell}$ SNH showed increase in comparison with control group. And in $500{\mu}g/m{\ell}$, $5000{\mu}g/m{\ell}$ SNH showed increase in case of 24 hours, 48 hours incubation, but showed decrease in case of 72 hours incubation. 6. I examined proliferation of spleen cells. As these results AMR and SNH showed the highest increase in $50{\mu}g/m{\ell}$, but showed the lowest increase in $5000{\mu}g/m{\ell}$. AR showed the highest increase in $500{\mu}g/m{\ell}$, but this result was the almost same in $50{\mu}g/m{\ell}$, $5000{\mu}g/m{\ell}$. And AMR, AR, SNH showed higher activity in Lipopolysaccharide than Concanavalin A. 7. In all groups results of PCA were decreased in 2 week. In 4 week AR and SNH showed decrease, but AMR didn't show change. In 6 week AR and SNH showed decrease, but on the contrary AMR showed increase. 8. In experimentation on histamine contents, AMR showed significant increase at first agent contact. And AR, SNH showed decrease at first agent contact, but these results were of no importance. At second agent contact AMR showed decrease, but was of no importance. AR, SNH showed significant decrease. At third agent contact, AMR showed significant increase. AR, SNH showed decrease, but these results were of no importance. From above these results, AR and SNH showed good effects on immunoreaction. And all the herb medicines in this examination showed good effects in promotion on spleen cells transformation and proliferation of spleen cells, especially activated B-cells. AR, SNH showed good effects on anti-allergic reaction, but AMR was almost inefficient. Accordingly I think that AR shall be used in disease bringing about a lowering of immunity, that is, AR shall be used in strengthening the body resistance. And I think that SNH shall be used in eliminating pathogenic factors with strengthening the body resistance. It is necessary to a deep study in future.

• The Journal of Korean Medicine
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• v.21 no.3
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• pp.31-39
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• 2000

Objectives : Chekamuiyiin-tang has effects of promoting diuresis, promoting blood circulation, elimating phlegm and strengthening the body's resistance to disease. We experimented with Chekamuiyiin-tang in order to find effects which might possibly cure obesity. Methods : We fed a control group of rats a high fat diet and administered normal saline for 8 weeks. And we fed an experimental group of rats a high fat diet and administered an extract of Chekamuiyiin-tang for 8weeks. Results : The serum total cholesterol level, triglyceride level, free fatty acid level, total lipid level and phospholipid level in the Chekamuiyiin-tang group showed a significant decrease in comparison with the control group. The serum HDL-cholesterol level in the Chekamuiyiin-tang group showed no change in comparison with the control group. The serum LDL-cholesterol level in the Chekamuiyiin-tang group showed a decrease in comparison with the control group, but this result showed no efficacy. The size of the epididymal fat cell and the fat drops area in the hepatic lobule of rats in the Chekamuiyiin-tang group showed a significant decrease in comparison with the control group. Conclusios : According to the above results, Chekamuiyiin-tang has shown to be capable of curing and preventing obesity.

• The Journal of Korean Medicine
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• v.27 no.1 s.65
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• pp.155-164
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• 2006

Objectives : The aim of this study is to review allergic rhinitis and to help make full use of oriental medical therapy in this disease. Methods : We investigated the published papers with the key word 'allergic rhinitis' and refered to several important old records Results : 1. Allegic rhinitis in Oriental Medicine is known as bigu, bunche and the main symptoms is rhinorrhea, sneezing, nasal obstruction. 2. The cause of allergic rhinitis in Oriental Medicine is dysfunctions of the spleen, lung and kidney systems bring weakness to the vital energy(正氣) making wind and cold(風寒邪氣) energy easy to intrude. 3. Determination of the patient's constitution and understanding of the weakness of spleen, lung and kidney systems helps improve the treatment rate, it is used to treat allergic rhinits with herbal medicines, acupunctures and so on. 4. In acupuncture therapy, the mainly used acupuncture points are 迎香(younghyang), 印堂(yindang), 鼻通(bitong), 上星(sangsung), 合谷(habgouk). Conclusions : The Oriental Medicine treatment principal of rhinitis is strengthening the body resistance and eliminating the pathogenic factors according to the individual characters of each patients and the symptoms.

• BMB Reports
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• v.55 no.1
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• pp.39-47
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• 2022

Adoptive cell transfer (ACT), a form of cell-based immunotherapy that eliminates cancer by restoring and strengthening the body's immune system, has revolutionized cancer treatment. ACT entails intravenous transfer of either tumor-resident or peripheral blood-modified immune cells into cancer patients to mediate anti-tumor response. Although these immune cells control and eradicate cancer via enhanced cytotoxicity against specific tumor antigens, several side effects have been frequently reported in clinical trials. Recently, exosomes, potential cell-free therapeutics, have emerged as an alternative to cell-based immunotherapies, due to their higher stability under same storage condition, lower risk of GvHD and CRS, and higher resistance to immunosuppressive tumor microenvironment. Exosomes, which are nano-sized lipid vesicles, are secreted by living cells, including immune cells. Exosomes contain proteins, lipids, and nucleic acids, and the functional role of each exosome is determined by the specific cargo derived from parental cells. Exosomes derived from cytotoxic effectors including T cells and NK cells exert anti-tumor effects via proteins such as granzyme B and FasL. In this mini-review, we describe the current understanding of the ACT and immune cell-derived exosomes and discuss the limitations of ACT and the opportunities for immune cell-derived exosomes as immune therapies.

• PNF and Movement
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• v.14 no.1
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• pp.49-52
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• 2016

Purpose: The purpose of the present study was to examine the effects of the area of the base of support formed by the human body on the maximal voluntary isometric contraction of upper limb muscles. Methods: The study was conducted with 20 normal adults. To identify changes in the base of support, the maximal voluntary isometric contraction of the biceps muscle was measured in a standing position, a sitting position, and a lying position for each subject. The sizes of the base of support formed in the standing, sitting, and lying positions were set to 1, 2, and 3 respectively, based on the sizes, to analyze the correlations. The maximal voluntary isometric contraction of the biceps muscle was measured using surface electromyograms (EMGs) (Noraxon DTS, Germany). Results: The results showed negative correlations in which, as the size of the base of support increased, the maximal voluntary isometric contraction of the biceps muscle decreased. Conclusion: Changes in the base of support of the body affect the maximal voluntary isometric contraction of the upper limbs. Therefore, when resistance exercises are applied for muscle strengthening, the positions should be changed considering the changes in muscle activity according to those positions. In addition, when EMGs are used to measure the maximal voluntary isometric contraction, the measurements should be conducted in the same positions, considering muscle activity that changes according to the base of support and positions, for data quantification.

• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.23-37
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• 2001

Objective: The purpose of this study is to develop and activate anti-tumor herbal acupuncture for cancer patients in South Korea. Methods: We investigated some literatures on anti-tumor herbal acupuncture which is used in South Korea and China, and made diagrams. Results: The results are summarized as follows. Anti-tumor herbal acupuncture is one of the traditional oriental medical method which is effective for cancer patients. In domestic studies, most of herb materials are belong to action of cooling&detoxification(25.0%) and strengthening body resistance(46.4%) which are proved to have effects of anti-tumor, immune activation and preventing tumor. In China, point injection therapy are used for improving symptoms of cancer patients and hea1ing tumor. Also herbal intravenous injection is used for combination of chinese traditional and western cancer therapy and treating cancer patients variously. Conclusions: From the above results. it is expected that anti-tumor herbal acupuncture is useful to improve clinical symptoms and quality of life(QOL) of cancer patients. Also we must develop new progressive methods of point injection and herbal intravenous injection for treating cancer patients, and advance clinical studies and trials.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.41-47
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• 2023

This study was conducted to determine the effect of an exercise program applied to prevent musculoskeletal changes that occur due to aging on pain, muscle strength, balance ability, and falling efficacy in elderly women. An exercise program including quadriceps setting exercise, bridge exercise, resistance band exercise, and foam roller exercise was applied to elderly women aged 65 years or older once a week for 8 weeks. A visual analog scale was used to evaluate pain, muscle strength was evaluated using a digital muscle strength meter, balance ability was measured using the Berg balance scale, and fear of falling was evaluated using the fall efficacy scale. As a result of the study, compared to before the experiment, pain in the lower back and knee area was significantly reduced, the strength of the quadriceps femoris and gluteus maximus was significantly increased, and balance ability and falling efficacy were significantly improved. In conclusion, application of a program that includes various exercise methods has a positive effect on the physical activity of elderly women by strengthening the musculoskeletal system. Additionally, in order to prevent physical changes due to aging, an exercise program that includes various exercise methods that can strengthen the musculoskeletal system should be applied.