• The Journal of Internal Korean Medicine
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• v.30 no.4
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• pp.799-805
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• 2009

Objectives : This study was aimed to assess characteristics in acute stroke patients according to abdominal obesity. Method : 1,506 subjects were included from the patients admitted to the Internal Medical Department at Kyunghee University Oriental Medical Center, Kyunghee University East-West Neo Medical Center, Kyungwon University Songpa Oriental Medical Center, Kyungwon University Incheon Oriental Medical Center, and D ongguk University Ilsan Oriental Medical Center from April 2007 to August 2009. Results : 1. Considering the demographic variables of the patients, the gender, older age, diabetes, hyperlipidemia and multiple infarction were significantly higher in the abdominal obesity group than in the control group. 2. Sasang constitution and oriental medical diagnosis showed significant difference in the abdominal obesity group. By oriental medical diagnosis, the D amp ness-Phlegm group was significantly higher in abdominal obesity group than in the control group. According to this analysis, we observed the general disposition of various characteristic distributions according to abdominal obesity in acute stoke patients These results can be utilized in the future as a basis material.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.586-595
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• 2004

Kamidojuk-San (KDJS) is known to be effective for treating cardiovascular diseases such hypertension, and clinically applied for the treatment of cerebral palsy or stoke patients. Yet, the overall mechanisms underlying its activity at the cellular levels are not known. Using experimental animal system, we investigated whether KDJS has protective effects on cells in cardiovascular and nervous systems. KDJS was found to rescue death of cultured primary neurons induced by AMPA, NMDA and kainate as well as BSO and Fe/sup 2+/ treatments. Moreover, KDJS treatment promoted animal's recovery from coma induced by a lethal dose of KCN treatment, and improved survival in animals exposed to lethal dose of KCN. Neurological examinations further showed that KDJS reduced the time which is required for animals to respond in terms of forelimb and hindlimb movements. To examine its physiological effects on cardiovascular and nervous systems, we induced ischemic injury in hippocampal neurons and cerebral neurons by middle cerebral artery (MCA) occlusion. Histological examination revealed that KDJS significantly protected neurons from ischemic damage. Thus, the present data suggest that KDJS may play an important role in protecting cells of cardiovascular and nervous systems from external noxious stimulations.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.69-69
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• 2011

본 논문에서는 비정상 상태의 비압축성 유동장을 해석하기 위하여 물체맞춤격자방법이 아닌 가상경계법을 사용하였다. 가상경계법은 구조격자를 사용하여 구조물 경계면에서 Momentum Forceing을 사용하여 가상의 경계를 만들어 유동장을 해석하는 방법이다. Navier-Stoke 방정식의 수치 이산화 방법으로 Kim et al(1985)이 사용한 Fractional Step Method(FSM)을 사용하였다. 시간에 대하여 semi-implicit FSM를 사용하였고, 확산항에 대해서는 2차 정확도의 Crank-Nicolson Method를 대류항은 3차 정확도의 Runge-Kutta Method를 사용 하였다. 본 연구에서는 가상경계법을 이용한 유동장 해석이 교량 단면에 대하여 수치해석이 가능한지 검토하였다. 가상경계법은 현재 많은 연구가 유선형의 구조물에 대하여 수행되어 오고 있다. 교량 단면과 같은 각 진 구조물에 대한 검토는 아직 미비한 실정이다. 가상경계법에서 다루고 있는 구조물 경계면에서의 Momentum Forcing 방법이 유선형의 구조물에 맞추어 연구가 진행되었기 때문이다. 먼저 본 연구의 프로그램을 검증하기 위하여 원형 실린더에 대하여 가상경계법을 적용한 결과 Re 수 200에서 Strouhal Number, 양력계수, 항력계수를 이전 연구 결과와 비교하였다. Williamson(1988)과 Zhang(1995)의 연구결과와 유사한 결과를 얻을 수 있다. 그리고 교량의 단면과 같은 각진 구조물(Bluff Body)에 대하여 가상경계법 적용하였다. 본 논문의 연구에서 평가 대상으로 하고 있는 2차원 교량 단면에 대하여 유동장 해석을 하였다. 본 논문에서 정량적인 유체력과 유동장에 대한 비교 및 검토가 이루어지지 못했지만 압력장과 유선의 형태가 이론적인 값을 벗어나지 않고 있는 것으로 확인 되었다. Re 수 2700에서 전산 해석을 수행하였으며, 교량 단면 주위의 압력계수와 박리현상 그리고 후류에서의 Vortex shedding 현상이 모두 적절한 분포가 나타나는 것을 확인할 수 있었다. 따라서 가상경계법을 이용하여 각진 구조물에 대한 주위 유동장해석에 대한 가능성을 확인하였으며, 풍동실험과의 결과비교를 통하여 가상경계법을 이용하여 교량 단면 주위의 유동장 해석 결과를 정량적으로 비교할 것이다.

• Korean Journal of Adult Nursing
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• v.12 no.1
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• pp.147-162
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• 2000

Predicting factors of post-stroke depression were investigated. The subjects were 254 stroke patients who had been discharged and visited regularly the outpatient clinic for follow up care. The influencing factors were classified into five categories : demographic, disease-related, current state, social support, and illness intrusiveness. Sex, age, job, and educational level were defined as the demographic factor. The disease-related factors included stroke type, illness duration, attack frequency, and NIH score. ADL, cognitive function, and social activity were considered as the current state factors. The social support was measured as the perceived amount of social support. Illness intrusiveness means the perceived illness induced life style disruptions. Demographic, disease-related, current state, and social support were hypothesized to directly and indirectly affect post-stroke depression through illness intrusiveness. The illness intrusiveness was hypothesized to directly affect post-stroke depression. The hierarchial multiple regression was used to identify significant factors. The result showed that this model explained 43.3% of variance of post-stroke depression. And the prevalence of post-stroke depression was 38.8%. Among the demographic factors, job was identified as a main contributor to indirectly increase the post-stroke depression. Among the disease-related factors, stroke type, attack frequency, and NIH score were found to indirectly affect the post-stroke depression. Among the current state factors, ADL and social activity indirectly affected the post-stroke depression through illness intrusiveness. Social support and illness intrusiveness were identified to directly affect the post-stroke depression. This study has proved the factors likely to be implicated in the development of post-stroke depression. Based upon these results, it is recommended that the nurses who take care of post-stroke patients consider the risk factors such as social support, illness intrusiveness et al. Also programs which decrease the illness intrusiveness and increase the social support to reduce post-stoke depression recommended to be developed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.36 no.5
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• pp.819-830
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• 2016

Hydrodynamic characteristics of wave propagation through density stratification have not been identified in details. So this study conducted a numerical simulation using LES-WASS-3D ver. 2.0 for analysis of density current due to water temperature and salinity in order to analyze hydraulic characteristics under wave action in a two-layer density stratified fluid. For the validity and effectiveness of numerical wave tank used, it was compared and analyzed with the experiment to show waveform based on $3^{rd}$-order Stoke wave theory at the internal of a density stratification. Using the results obtained from numerical simulation, the surface and internal wave heights are reduced as the wave propagates in a two-layer density stratified water. And the surface or internal wave attenuation became more serious as the vorticities were increased by the velocity difference of wave propagation due to the upper-lower density difference around the interface of a density stratification. As well, the surface and internal wave attenuations became more serious with higher density difference and depth ratio between upper and lower layers when the wave propagates through a density stratification.

• The Journal of Internal Korean Medicine
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• v.19 no.2
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• pp.50-59
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• 1998

Background : Vascular dementia occurs mainly due to cerebral vascular disease. So we performed this clinical study to investigate the incidence and characteristics of vascular dementia in stroke patients. Methods : This study was performed on the patients hospitalized from April 1, 1998 to August 31, 1998 at the department of circulatory internal medicine, hospital of Oriental medicine, Kyung-Hee University, and diagnosed cerebral infarction or hemorrhage by Brain CT or MRI. we devided the patients into two groups; vascular dementia group and non dementia group according to MMSE-K(Mini Mental State Examination Korean version), Hasegawa dementia scale. Patients were diagnosed dementia using DSM-IV. We compared general characteristics, stoke types and laboratory findings between the two groups and investigated the correlationship between MMSE-K and Hasegawa dementia scale. Results : Results showed that the incidence of vascular dementia was about 27.8% in stroke patients. The greater number of subjects with dementia were women in the lower educational classes and had lower MBI(Moderfied Bathel Index) scores. Vascular dementia were more common in patients with large brain lesion size($>20cm^3$). There was a positive correlationship between Hasegawa scores and MMSE-K.

• The Journal of Korean Medicine
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• v.27 no.1 s.65
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• pp.118-129
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• 2006

Objectives : A human being is classified into 4 constitutions(Taeyangin, Soyangin, Taeumin, and Souemin) and each constitution has the different incidence, treatment and prevention of disease in Sasang Constutional Medicine[SCM], The purpose of this study is to find relative risk(RR)s of each risk factors including Sasang Constitution[SC] for incidence of ischemic stroke. Methods : In 344-case patients with ischemic stroke and 1446 healthy control subjects without ischemic stroke, we evaluated sex, age. height, weight, BMI, ECG abnormality, hypertension, diabetes mellitus, blood lipid level and SC. These data were statistically analysed to investigate the relations between risk factors and the incidence of ischemic stroke by chi-square test. And then significant factors were analysed to get each adjusted odds ratio[OR] by binary logistic regression analysis. Results : ECG abnormality, hypertension, diabetes mellitus, HDL(high density lipoprotein) cholesterol, and SC were significantly related to the incidence of ischemic stroke, while age, sex and BMI were adjusted in a binary logistic regression analysis. Especially in SC, the incidence of ischemic stoke in Tae-eumin and Soyangin were higher than that in Soeumin (Tae-eumin OR=11.68[95% CI: 6.26-21.80], Soyangin OR=4.64[95% CI: 2.66-8.10]). Conclusions : These results suggested that SC may be one of important risk factors for ischemic stroke and it should be a useful data for prediction of incidence of ischemic stroke.

• The Journal of Internal Korean Medicine
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• v.37 no.6
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• pp.990-997
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• 2016

Objectives: This study observed changes in gait pattern according to the motor grade of the paretic lower limb in patients with basal ganglia stroke who are in the subacute phase. Methods: We used the Manual Muscle Test (MMT) to evaluate the motor grade of the paretic lower limb of 21 patients with subacute basal ganglia stroke and then divided them into two groups based on the MMT results. Stroke patients with a motor grade above Gr. III were put in group I (15 people) and those with a grade less than Gr. III in group II (6 people). We also estimated spatiotemporal factors using treadmill gait analysis equipment. The values were gait velocity, step length, step time, double support phase, and cadence. The first measure was conducted during the early period of admission and the second was between four and five weeks after admission. Results: In Group I, the gait velocity and step length of both legs significantly increased. In Group II, the step length and step time of the paretic side and the gait velocity tended to decrease, but not significantly. The step length of the paretic side in Group II was significantly longer than that in Group I at the first measure. The step time of the paretic side in Group I was significantly shorter than that in Group II and gait velocity and cadence in Group I were significantly higher than in Group II at the second measure. Conclusions: The gait parameters of all stroke patients improved in terms of time. In addition, the changes in gait pattern were different depending on the motor grade of the paretic lower limb.

• The Journal of Internal Korean Medicine
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• v.41 no.2
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• pp.204-212
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• 2020

This study aimed to investigate the effect of traditional Korean medical treatments on a stroke patient with gait disturbance, cognitive impairment, dysuria, and dysphagia. A 78-year-old female with chronic middle cerebral artery infarction had symptoms of gait disturbance, cognitive impairment, dysuria, and dysphagia. After being treated with Korean medicine therapies, including acupuncture and herbal medicine, the patient's symptoms were significantly improved. During all the treatments, Indices including manual muscle test, functional ambulation category, functional independence measuring, mini-mental state examination-K, global deterioration scale, pelvic symmetry, functional ambulation profile used to evaluate her symptoms indicated improvement in her symptoms, without any side effects. Traditional Korean medical treatments, such as acupuncture and herbal medicine, can be considered to be effective therapies for a stoke patient who has symptoms of gait disturbance, cognitive impairment, dysuria, and dysphagia.

• The Journal of Korean Physical Therapy
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• v.22 no.4
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• pp.15-20
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• 2010

Purpose: The purpose of this study was to measure changes in the H-reflex and V wave under loading conditions (e.g. prone and standing position) and to investigate whether postural change would affect the H-reflex and V wave in post stroke hemiplegic patients. Methods: Thirty persons with hemiplegia resulting from stroke (20 males, 10 females) participated in this study. Electromyography (EMG) was used to electrically stimulate and record the soleus H-reflexes and V waves under various loading conditions. The normality of the distribution of each variable (H latency, $H_{max}/M_{max}$ ratio, $V_{max}/M_{max}$ ratio) was tested using the Kolmogorov-Smirnov test. The means of normally distributed continuous data were assessed by independent t-test (${\alpha}$=0.05). Results: There were statistically significant differences in $H_{max}/M_{max}$ ratio (p<0.01), $V_{max}/M_{max}$ ratio (p<0.01), H latency (p<0.01) among the prone and standing position. Conclusion: We found that the H-reflex and V wave in standing position was more active to weight bearing load than prone position.