• Title/Summary/Keyword: stochastic generation

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A Study on the Genetic Risk and Carcinogenesis Probability of Prostate Cancer Patients Due to Photoneutron Generation (광중성자 발생으로 인한 전립샘암 환자의 유전적 위험과 발암의 확률에 관한 연구)

  • Joo-Ah Lee
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.473-479
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    • 2023
  • In this study, the dose of photoneutrons generated during radiotherapy of prostate cancer using high energy was measured using a photo-stimulated luminescence dosimeter. In addition, this study was intended to study the probability of side effects occurring in the abdomen. A medical linear accelerator capable of generating 15 MV energy, True Beam STx (Varian Medical Systems, USA) and a radiation treatment planning system (Eclipse, Varian Medical Systems, USA) were used. A human body phantom was installed on the couch of the linear accelerator, and an Albedo Neutron Optical Stimulation Luminescence Neutron Detector (Landauer Inc., IL, USA) was used to measure the photoneutron dose. The photoneutron dose value in the abdomen of VMAT and 3C-CRT was 52.8 mSv, more than twice as high as VMAT compared to 3D-CRT. During radiotherapy of prostate cancer, the probability of causing side effects in the abdomen due to light neutron dose was calculated to be 3.2 per 1,000 for VMAT and 1.4 for 3D-CRT. By studying the abdomen, which has a major side effect that can occur during radiotherapy of prostate cancer, it is expected that it will be used as a meaningful study to study the quality of life and stochastic effect of prostate cancer patients