• Geotechnical Engineering
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• v.10 no.2
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• pp.41-56
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• 1994

Under the groundwater level, the tunnel face is affected by the seepage force and the groundwater flow may cause a trouble to the tunnel support systems. The appropriate methods of analysis and design in the tunnel face and the lining, considering groundwater flow according to tunnel drainage condition are presented in this thesis. First, the effect of seepage on the stability of tunnel face was studied. Seepage force was estimated by the 3-D finite element analysis and the stability of tunnel face was checked by analytical method. Furthermore, using the finite difference method the stress and displacement on the face were computed for either case, where the seepage force is or is not considered, and the effect of seepage on the tunnel face stability was evaluated. Second, the effect of seepage force on the tunnel lining when construction is finished and steady state seepage flow occurs was studied and a design methodology considering seepage effect was made. Consequently, in case where the groundwater level remains almost unchanged and the steady state groundwater flow occurs, the proper countermeasures for face staility are required according to the condition of groundwater flow. Moreover, the tunnel lining should be designed and constructed considering the seepage force occuring by the groundwater flow toward the tunnel linings.

• The Journal of Engineering Geology
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• v.11 no.3
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• pp.255-267
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• 2001

A comparison study is performed to understand the coupling behavior of the thermal, hydraulic, and mechanical interactions in the vicinity of an underground radwaste repository, assumed to be located at a depth of 500 m, within a granitic rock mass with a 58$^{\circ}$ dipping fault passing through the roof-wall intersection of the repository cavern. The two dimensional universal distinct element code, UDEC is used for the analysis. The model includes a granitic rock meas, a canister with PWR spent fuels surrounded by the compacted bentonite inside a deposition hole, and the mixed bentonite backfilled in the rest of the space within a repository cavern. The coupling behavior of hydromechanical, thermomechanical, and thermohydromechanical interaction has been studied and compared. The effect of the time-dependent decaying heat, from the radioactive materials in PWR spent fuels, on the repository and its surroundings has been studied. A steady state flow algorithm is used for the hydraulic analysis.

• Archives of Pharmacal Research
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• v.21 no.4
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• pp.411-417
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• 1998

In order to investigate the effect of the pretreatment with various doses of diltiazem (DTZ) on the pharmacokinetics of indocyanine green (ICG) at steady state, especially the hepatic blood clearance due to the change of hepatic blood flow, the following experiments were carried out with ICG, a hepatic function test marker, not metabolized in liver and only excreted in bile. The intravenous bolus injection ($3,780\mu\textrm{g}$/kg) and the constant-rate infusion ($10,100\mu\textrm{g}$/kg/hr) of ICG into the left femoral vein were made in order to check the steady-state plasma concentration ($C_{ss} of $10\mu\textrm{g}$/ml) of ICG at 20, 25 and 30 min. Following a 90-min washout period, the intravenous bolus injection (108, 430, 860 and $1,720\mu\textrm{g}$/kg) and the constant-rate infusion (108, 433, 866 and $1,730\mu\textrm{g}$/kg/hr) of DTZ into the right femoral vein were made and the achievement of the steady-state plasma levels ($C_{ss} of 50, 200, 400 and 800 ng/ml) of DTZ were conformed at 60, 70 and 80 min. During the steady state of DTZ, the intravenous bolus injection ($3,780\mu\textrm{g}$/kg) and the constant-rate infusion ($10,200\mu\textrm{g}$/kg/hr) of ICG into the left femoral vein were made and also the steady-state plasma concentration of ICG was checked at 20, 25 and 30 min. The plasma concentrations of DTZ and ICG were determined using a high performance liquid chromatographic technique. At the steady state, the hepatic blood clearance of ICG was obtained from the plasma concentration and blood-to-plasma concentration ratio ($R_B$) of ICG. The pretreatment with various doses of DTZ did not influence the plasma concentrations, $R_B$ and plasma free fraction ($f_p$) of ICG. So the hepatic blood clearance of ICG was independent of concentration of DTZ. The hepatic blood clearance of ICG could be affected by both hepatic bood flow and hepatic intrinsic clearance. But there was no change of the hepatic blood clearance of ICG between the control and the DTZ-pretreated rats in this study. So it may be suggested that DTZ does not influence hepatic blood flow.

• Journal of the Korean Solar Energy Society
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• v.23 no.3
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• pp.55-61
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• 2003

This paper represents the effect of rotor geometry on the performance of a small-scale Wells turbine for wave energy conversion. In this study, four kinds of blade profile were selected from previous studies with regard to the blade profile of the Wells turbine. The experimental investigations have been performed for two solidities by model testing under steady flow conditions, and then the effect of blade profile on the running and starting characteristics under sinusoidal flow conditions have been investigated by a numerical simulation using a quasi-steady analysis. In addition, the effect of sweep on the turbine characteristics has been investigated for the cases of CA9 and HSIM 15-262123-1576. As a result, a suitable choice of these design factors has been suggested.

• Management Science and Financial Engineering
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• v.16 no.1
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• pp.119-135
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• 2010

In this paper, we readdress the optimization problem for minimizing the inspection cost in a back-light unit inspection system, which forms a network including a K-stage inspection system, a source inspection shop, and a re-inspection shop. In order to formulate our objective function when the system is in a steady state, assuming that the number of nonconforming items in a lot follows a binomial distribution when a lot is formed for inspection, we make a steady-state network flow analysis between shops, and derive the steady-state amount of flows between nodes and the steady-state fraction defectives by solving a nonlinear balance equation. Finally we provide some fundamental properties and an enumeration method for determining an optimal value of K which minimizes our objective function. In addition, we compare our results numerically with previous ones.

• Journal of Advanced Marine Engineering and Technology
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• v.31 no.3
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• pp.272-281
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• 2007

A numerical simulation on nitrogen gas flow in a long parallel plate microchannel was performed to obtain the effect of compressibility and rarefaction on gaseous flow in microchannels. The simulation was based on steady. two dimensional compressible Navier-Stokes and energy equations with noslip and first order slip boundary conditions. The channel was $1.2{\mu}m$ deep and $3000{\mu}m$ long. The Reynolds numbers were in the range of order from $10^{-2}$ to $10^{-1}$. So the flow was assumed to be laminar. The computations were performed on various pressure ratios. The outlet pressure was fixed to atmospheric pressure. The outlet Knudsen number was 0.0585, consequently the flow was in the slip flow regime. The computations were performed with the assumption of isothermal channel walls. The results were compared with the experimental data. The agreement was good.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.2
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• pp.158-165
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• 1996

The knowledge of air flow in an engine room has become more and more important in recent car design. The fluid flow in the engine compartment was investigated by numerical analysis. Due to the complex geometry of the engine compartment, mesh generation is a time-consuming job. In this research, the "ICEM" code was used to generate meshes by the Cartesian mesh model. The Reynolds-averaged Navier Stokes equations, together with the porous flow model for radiator and condenser, were solved. Computation was performed for the steady, incompressible, and high speed viscous flow, adopting the standard K-ε turbulence model. The "STAR-CD" code was used as a solver. The effect of car front openning area on the flow in engine room was also investigated.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.711-722
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• 2008

A projectile when passes through a moving shock wave, experiences drastic changes in the aerodynamic forces as it moves from a high-pressure region to a low pressure region. These sudden changes in the forces are attributed to the wave structures produced by the projectile-flow field interaction, and are responsible for destabilizing the trajectory of the projectile. These flow fields are usually encountered in the vicinity of the launch tube exit of a ballistic range facility, thrusters, retro-rocket firings, silo injections, missile firing ballistics, etc. In earlier works, projectile was assumed in a steady flow field when the computations start and the blast wave maintains a constant strength. However, in real situations, the projectile produces transient effects in the flow field which have a deterministic effect on the overtaking process. In the present work, the overtaking problem encountered in the near-field of muzzle guns is investigated for several projectile Mach numbers. Computations have been carried out using a chimera mesh scheme. The results show that, the unsteady wave structures are completely different from that of the steady flow field where the blast wave maintains a constant strength, and the supersonic and subsonic overtaking conditions cannot be distinguished by identifying the projectile bow shock wave only.

• Bulletin of the Korean Chemical Society
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• v.27 no.10
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• pp.1618-1622
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• 2006

Bacteriophage T7 gp4A' is a ring-shaped hexameric DNA helicase that catalyzes duplex DNA unwinding using dTTP hydrolysis as an energy source. To investigate the effect of single-stranded DNA (ssDNA) on the kinetic pathway of dTTP hydrolysis by the T7 DNA helicase complexed with ssDNA, we have first determined optimal concentration of long circular M13 single-stranded DNA and pre-incubation time in the absence of $Mg^{2+}$ which is necessary for the helicase-ssDNA complex formation. Steady state dTTP hydrolysis in the absence of $Mg^{2+}$ by the helicase-ssDNA complex provided $k_{cat}$ of $8.5\;{\times}\;10^{-3}\;sec^{-1}$. Pre-steady state kinetics of the dTTP hydrolysis by the pre-assembled hexameric helicase was monitored by using the rapid chemical quench-flow technique both in the presence and absence of M13 ssDNA. Pre-steady state dTTP hydrolysis showed distinct burst kinetics in both cases, indicating that product release step is slower than dTTP hydrolysis step. Pre-steady state burst rates were similar both in the presence and absence of ssDNA, while steady state dTTP hydrolysis rate in the presence of ssDNA was much faster than in the absence of ssDNA. These results suggest that single-stranded DNA stimulates dTTP hydrolysis reaction by T7 helicase by enhancing the rate of product release step.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.6
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• pp.1-12
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• 1997

In an SI engine, the characteristics of the air flow is important not only for the design of the intake system geometry but also for the accurate measurement of the induction air mass. In this study, an air flow rate measurement using the ultrasonic flow meter and hot wire flow meter was conducted at the upstream of the intake port and the throttle. At the upstream of the intake port, the pulsating flow into the cylinder affected by the pressure wave was detected directly with the flow meters instead of pressure sensors. At the upstream of the throttle, the reverse flow phenomena were showed by comparing the flow pattern measured by the hot wire air flow meter and the ultrasonic air flow meter. The results of this study can be used for the analysis of the tuning effect in the intake manifold and estimation of the error in real time measurement for the air flow rate.