• Journal of Acupuncture Research
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• 제25권6호
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• pp.47-54
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• 2008

Objectives : This study was aimed to figure out how effectively acupuncture treatment and herb-medicine work on patients with elevation of LFT value and lipid-obesity index. Methods : The subject were 23 patients visited to Dept. of Acupuncture and Moxibustion, Kwangdong Oriental Medicine Hospital, who complained chronic fatigue and wandering pain from Oct. 2007. to Oct. 2008. Before treatments, they were tested for LFT, total cholesterol, triglyceride, body fat ratio and obesity index. They were treated with Ganjeonggyeok acupuncture weekly for 1 month. During acupuncture treatments, we applied Sangkankunbi-tang to all patients twice a day. After 1 month, they were retested for LFT, total cholesterol, triglyceride, body fat ratio and obesity index. Results : 1. After treatments, we could get the result of dropping means of AST, ALT and $\gamma$-GTP value. Statistical significance of ALT and $\gamma$-GTP were recognized before and after treatments, but AST was not recognized. 2. After treatments, we also could get the result of dropping means of total cholesterol, triglyceride, body fat ratio and obesity index. Statistical significance of all values were recognized before and after treatments. 3. Among 23 patients, 10 cases were reported that they were not within normal limits at least one in AST, ALT and $\gamma$-GTP. After treatments of those patients, we could get the result of dropping means of AST, ALT and $\gamma$-GTP value. Statistical significance of all values were recognized before and after treatments. 4. Among 23 patients, 19 cases were reported that they were not within normal limits at least one in total cholesterol, triglyceride, body fat ratio and obesity index. After treatments of those patients, we could get the result of dropping means of total cholesterol, triglyceride, body fat ratio and obesity index. Statistical significance of all values were recognized before and after treatments. Conclusions : Though further study is necessary, our finding suggest that the conduction of Ganjeonggyeok acupuncture and Sangkankunbi-tang treatments have helped to decrease the figures of LFT and lipid-obesity index in patients.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권4호
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• pp.287-294
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• 2011

Introduction: Ameloblastoma is a benign but locally invasive tumor with a high recurrence rate. The aim of this study was to make an easier diagnosis and treatment planning of ameloblastoma. Materials and Methods: From January 1993 to October 2009, 139 cases from 123 patients, who had been diagnosed with ameloblastoma through radiologic and biopsy in the department of oral and maxillofacial surgery of Kyunpook National University, were selected as the subjects in this study. According to the medical charts, 9 factors (age, gender, location, chief complaints, duration, radiographic findings, size and recurrence) concerned in deciding the treatment method and the relevance between each factor and the treatment methods were examined.(Conservative treatments were marsu-pialization, enucleation, curettage and lateral decortication. Radical treatments included block excision, resection and hemisection) Results: In the patients under the age of 20, 77.14% had conservative treatments, whereas 22.86% underwent radical treatments. In the patients over the age of 20, 44.23% were treated conservatively treatments, and 55.77% underwent radical treatments. For unilocular types, 28.57% had conservative treatments, whereas 71.43% had radical treatments. For the multilocular types, 66.67% underwent conservative treatments, and 33.33% had radical treatments. For the primary cases, 58.68% were treated conservatively and 41.32% had radical treatments. For the recurrent cases, 16.67% and 83.33% underwent conservative and radical treatments, respectively. Conclusion: There was statistical significance in the factors affecting the treatment methods, such as age, radiographic findings and recurrence.

• Journal of Acupuncture Research
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• 제34권3호
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• pp.23-38
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• 2017

Objectives : The purpose of this study was to evaluate the clinical prognostic factors affecting facial palsy in 98 idiopathic facial palsy patients who were hospitalized and treated in 2015, using retrospective statistical analysis. Methods : We investigated patients with idiopathic facial nerve palsy, admitted to a Korean medical hospital in 2015, and examined patients' variables and therapeutic variables. For analysis of clinical data, an independent sample t-test, analysis of variance (ANOVA), and simple regression analysis were performed using IBM SPSS version 24.0. Results : 1. The initial degree of facial palsy showed statistical significance with age. The older the age, the more severe the initial palsy. 2. Following treatment degree of facial palsy was statistically significant with age, hypertension, and fasting blood sugar (FBS). The higher the value, the slower the recovery from facial palsy. There was a statistical significance with the number of treatments in a Korean medical hospital. The more frequent the treatment, the faster the facial palsy recovery. 3. Degree of facial palsy after 12 months was statistically significant with age, hypertension, diabetes, FBS, and the initial severity of facial palsy. The higher the value, the slower the facial palsy recovery. 4. Sex, left or right sided palsy, alcohol consumption, smoking, history of facial palsy, season of onset, total number of treatments and bio chemistry (BC), complete blood cell count (CBC), urinalysis (UA) factors had no statistical significance with prognosis of facial palsy. Conclusion : Age, season of onset, hypertension, diabetes, FBS, initial severity of facial palsy, and the number of treatments at a Korean medical hospital showed statistical significance. The number of treatments at the Korean medical hospital positively correlated with facial palsy prognosis, and the others variables showed a negative correlation with facial palsy prognosis.

• Journal of the Korean Statistical Society
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• 제14권1호
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• pp.48-55
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• 1985

In clinical trials subjects are avalible sequentially and must be assigned to treatments immediately. Completely randomized procedure for the allocation of treatments to each subject may result in severe imbalance among the number of subjects in treatment groups, especially for small experiments or interim analyses of large experiments. In this study, restricted randomization methods such as biased coin designs (Efron, 1971), permuted block design, and truncated binomial design are compared to teh completely randomized design in the presence of selection and/or accidential bias by Monte Carlo simulations.

• Journal of the Korean Statistical Society
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• 제1권1호
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• pp.11-17
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• 1973

A class of sequential binomial tests and a sequential rank test can be applied for testing two treatments when subjects are paired in many-to-one ratio. The efficiency of each test is examined in terms of the average sample number. The binomial tests are much easier and more convenient to apply than the rank test not as efficient. Within the class of binomial test, the median test appears to be the most efficient is general.

• Journal of the Korean Statistical Society
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• 제3권2호
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• pp.85-101
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• 1974

In a Balanced Factorial Experiments (BFE) with n factors $F_1, F_2,\cdots,F_n$ at $m_1, m_2,\cdots,m_n$ levels respectively, Shah [15] has considered the following association scheme: the two treatments are the $(P_1, P_2,\cdot,P_n)$th associates, where $p_i=1$ if the ith factor occurs at the same level in both treatments and $p_i=0$ otherwise; $\lambda_{(p_1,p_2,\cdots,p_n)}$ will denote the number of times these treatments occur together in a block. He has showed that a BFE is partially Blanced Incomplete Block(PBIB) design with repsect to the above association scheme. Kurjian and Zelan [6] have proved that factorial designs possessing a Property A (a particular structure for their matrix NN') are factorially balanced.

• Communications for Statistical Applications and Methods
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• 제6권1호
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• pp.159-168
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• 1999

We introduce a new conditional signed-rank test for the tree alternatives comparing several treatments with a control in the randomized block design. We demonstrate its performance by comparing with 3 classes of signed-rank tests proposed by Park et al.(1991) in some general situations. In most cases the proposed procedure is simpler to compute and has better power than others.

• Journal of the Korean Statistical Society
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• 제15권1호
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• pp.26-30
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• 1986

Basu (1980) examined Fisher Randomization Test (FRT) of matched pair experimental data with critical point of view. Additionally, Lane (1980) pointed out that "the experimenter may be interested in a weaker notion of equality between two treatments, " than the notion of equality which FRT relies on. In this study, a randomization test is developed so that it can test a weaker hypothesis of equality. equality.

• 동의생리병리학회지
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• 제26권4호
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• pp.557-565
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• 2012

The purpose of this study was to examine the effect of acupuncture on trunk flexors compared with trunk extensors in patients with chronic low back pain. The experimental group was treated with acupuncture on trunk flexors. The control group was treated with acupuncture on trunk extensors. Acupuncture treatment was performed 12 sessions over the course of 6 weeks. Volunteers who satisfied the requirements were enrolled in the study. Chronic low back pain was evaluated based on the VAS for bothersomeness, VAS for pain intensity at every treatment and 8, 12 and 24 weeks after starting the treatments, and ODI, SF-36 and BDI before and after treatments and 8, 12 and 24 weeks after starting the treatments. The VAS score for bothersomeness significantly decreased after treatment for up to 24 weeks after starting the treatments in both group (p<0.05). The VAS score for bothersomeness in the experimental group decreased more rapidly than that of the control group with statistical significance (p<0.05). The VAS score for pain intensity, ODI, SF-36 and BDI significantly improved after treatment for up to 24 weeks after starting the treatments in both group (p<0.05). The VAS score for pain intensity, ODI, SF-36 and BDI in the experimental group showed more rapid improvement than those of the control group. But, there were no statistical significances. Treating trunk flexors using acupuncture was more effective in decreasing the degree of bothersomeness caused by chronic low back pain than treating trunk extensors with acupuncture. There is a need to perform further studies.

• Communications for Statistical Applications and Methods
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• 제16권6호
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• pp.945-957
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• 2009

의약학 분야에서는 여러 집단에서 하나의 반복요인을 가지는 반복측정 자료가 많이 사용된다. 이 논문에서는 대조군과 처리군들의 시간에 따른 반응값의 선형추세를 비교하기 위하여 각 개체의 기울기를 추정하고 추정된 기울기들에 의해 생생된 표본으로 F-test, Jonckheere-Terpstra test, updated control group procedure를 이용하여 대조문과 처리군들의 차이를 검정하는 방법을 제안하였다. 모의실험 (Monte Carlo Simulation)을 통해 실험유의수준(experimental significance level)과 검정력(power)을 비교하였다.