• 한국방사선학회논문지
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• 제17권7호
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• pp.1025-1031
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• 2023

저선량흉부 CT (Low Dose chest CT, LDCT)에서 Scout 관전압을 변화시키고 scan parameter인 자동노출제어장치(Auto Exposure Control, AEC)와 적응식 반복재구성기법(Adaptive Statistical Iterative Reconstruction, ASIR)등을 적용하여 최적의 프로토콜을 찾음으로써 방사선 피폭선량과 화질을 평가하고자 하였다. Scout 관전압을 80, 100, 120, 140 kV로 변화시키며 LDCT 프로토콜로 5회 반복 측정 후 선량을 비교하기 위해 장비에서 제공된 Dose report를 이용하여 연구 목적에 적합한 관전압을 선택하였다. 120 kV, 30 mAs의 조건으로 기본 LDCT 촬영한 후, 이 조건에 ASIR 50%를 적용하였으며 신호대잡음비와 대조도대잡음비를 평가하기 위해 배경의 노이즈를 측정하였다. 선량 비교를 위해 장비에서 제공되는 CTDI_vol과 선량길이곱(Dose length product, DLP)를 식을 이용하여 비교 분석하였다. 그 결과 S140 + LDCT + ASIR 50 + AEC를 적용한 프로토콜에서 고식적인 LCDT보다 방사선 피폭선량을 감소시키고 영상의 질을 향상시켰으며 최적의 프로토콜을 얻을 수 있었으며 LDCT는 매 검사 시 필요 이상의 피폭선량이 우려되기 때문에 적절한 Parameter를 적용하는 것이 중요하며, 향후 LDCT를 이용한 건강검진에서 국민의 건강에 이바지 하는데 긍정적인 요인으로 작용될 것으로 사료된다.

• ETRI Journal
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• 제32권5호
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• pp.801-809
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• 2010

This paper presents a statistical model-based noise suppression approach for voice recognition in a car environment. In order to alleviate the spectral whitening and signal distortion problem in the traditional decision-directed Wiener filter, we combine a decision-directed method with an original spectrum reconstruction method and develop a new two-stage noise reduction filter estimation scheme. When a tradeoff between the performance and computational efficiency under resource-constrained automotive devices is considered, ETSI standard advance distributed speech recognition font-end (ETSI-AFE) can be an effective solution, and ETSI-AFE is also based on the decision-directed Wiener filter. Thus, a series of voice recognition and computational complexity tests are conducted by comparing the proposed approach with ETSI-AFE. The experimental results show that the proposed approach is superior to the conventional method in terms of speech recognition accuracy, while the computational cost and frame latency are significantly reduced.

• Archives of Plastic Surgery
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• 제35권5호
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• pp.533-538
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• 2008

Purpose: Sensory changes in the upper limb are complications of a mastectomy with immediate breast reconstruction with the treatment of breast cancer. The purpose of this study is to clarify whether immediate breast reconstruction worsens the sensory changes. Methods: From March 2004 to December 2005, 20 patients who had a mastectomy with immediate breast reconstruction(reconstruction group) were compared with 23 patients who had a mastectomy alone(control group). All patients had stage I or II breast cancer. The sensory changes were assessed in a blind manner by one examiner that used light touch sensation, static two-point discrimination, pain, vibration, hot and cold temperature perception. The sensory changes were identified along the sensory dermatome for diagnosing the damaged nerves. The following factors and their relationship with the sensory changes were analyzed : age, complications, and the mastectomy method. Results: There was no statistical difference in the static two-point discrimination, pain, vibration, hot and cold temperature perception between the two groups. However, the ability to recognize light touch was significantly better(p=0.045) in the reconstruction group than in the control group. The main site of sensory change was the proximal and medial portion of the upper limb in both groups. At these sites, the mean value of Semmes-Weinstein monofilament was $1.01g/mm^2$(reconstruction group 0.82, control group 1.17) and 2-point discrimination was 51.74(converted to perfect score of 100; reconstruction group 42.50, control group 59.78). The total rate of early complications was found to be significantly lower(p=0.006) in the reconstruction group than in the control group. Conclusion: These findings suggest that an immediate breast reconstructive procedure following a mastectomy is as safe as or safer than a mastectomy alone with respect to postoperative sensory changes of the ipsilateral upper limb.

• 한국임상수의학회지
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• 제30권4호
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• pp.268-272
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• 2013

The purpose of this study was to assess the effects of reconstruction kernel, and slice thickness on the accuracy of spiral CT-based volume assessment over a range of object sizes typical of synthetic simulated tumor. Spiral CT scanning was performed at various reconstruction kernels (soft tissue, standard, bone), and slice thickness (1, 2, 3 mm) using a phantom made of gelatin and 10 synthetic simulated tumors of different sizes (diameter 3.0-12.0 mm). Three-dimensional volume assessments were obtained using an automated software tool. Results were compared with the reference volume by calculating the percentage error. Statistical analysis was performed using ANOVA and setting statistical significance at P < 0.05. In general, smaller slice thickness and larger sphere diameters produced more accurate volume assessment than larger slice thickness and smaller sphere diameter. The measured volumes were larger than the actual volumes by a common factor depending on slice thickness; in 100HU simulated tumors that had statistically significant, 1 mm slice thickness produced on average 27.41%, 2 mm slice thickness produced 45.61%, 3 mm slice thickness produced 93.36% overestimates of volume. However, there was no statistically significant difference in volume error for spiral CT scans taken with techniques where only reconstruction kernel was changed. These results supported that synthetic simulated tumor size, slice thickness were significant parameters in determining volume measurement errors. For an accurate volumetric measurement of an object, it is critical to select an appropriate slice thickness and to consider the size of an object.

• 핵의학기술
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• 제18권1호
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• pp.134-139
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• 2014

ASIR기법은 statistical noise modeling을 사용하여 CT image를 reconstruction하는 방법으로, mA를 낮춰도 이미지 질을 보전하며 noise reduction 효과가 있다고 알려져 왔다. 본 논문은 본원에서 주로 하는 bone SPECT/CT에 ASIR 기법을 적용하여 이미지를 평가하였다. GE의 Discorvery 670을 이용하여 120 kVp, 100 mA를 기준으로 mA를 변화시켜서 ASIR의 적용 전과 적용 후 영상을 비교하였다(ASIR level: 20-80%). Anthropomorphic phantom으로 ASIR (%)의 변화에 따른 SPECT image의 감쇠 보정 정도를 측정하였다. 두번째로 ACR phantom으로 CT image의 CNR, image noise, spatial resolution을 평가하였다. 세 번째로 lower torso phantom을 이용하여 spine에 최적화할 수 있는 ASIR level을 선택한 후 2명의 bone SPECT/CT follow up 환자에게 ASIR를 적용하여 영상을 획득한 후 5년 이상의 경험이 있는 10명의 방사선사에게 blind test를 시행하였다. SPECT의 영상의 감쇠 보정 정도는 ASIR의 변화와는 무관하게 모두 유의한 차이가 없었다(P>0.05). ASIR을 적용했을 때 CT image의 noise는 mA의 변화에 따라 최소 17%에서 최대 52%까지 감소하였다. ASIR를 적용하지 않았을 때 CNR은 40 mA에서 0.42를 보여준 반면 ASIR를 적용한 40 mA (ASIR 60%)에서도 0.8 이상을 유지하였다. High contrast 영역의 비교에서는 ASIR 적용과 상관없이 40 mA까지 12 lp/cm 영역을 구별할 수 있었다. Lower torso phantom의 spine image에서 100 mA image와 육안적으로 비슷한 ASIR level은 60% (40 mA) 정도였고, bone SPECT/CT에 적용한 후 blind test에서 육안적으로 ASIR를 적용하지 않았을 때와 차이를 구별하지 못하였다. 본 논문의 결과는 SPECT/CT에서 ASIR 기법을 사용했을 때 SPECT와 CT image의 특별한 영상의 질 저하 없이 radiation dose를 줄일 수 있다는 것을 보여준다. 또한 관심부위가 bone에 한정되어 있는 bone SPECT/CT 특성상 더 높은 ASIR level도 가능할 것으로 사료된다.

• 한국광학회지
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• 제19권6호
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• pp.389-393
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• 2008

본 논문에서는 컴퓨터 집적영상(integral imaging(II))에서 분산 추정을 이용하여 심하게 은폐된 물체의 복원 시 은폐물(occluding object)의 블러링 효과를 제거하는 방법을 제안하였다. 하나의 요소영상(elemental image) 군으로부터 은폐 효과를 제거하여 복원된 영상의 선명도를 향상시키는 정보를 추출하는 방법을 분석하였다. 이를 실행하기 위해 픽업되는 요소영상들이 높은 해상도, 낮은 초점오차(focus error), 큰 깊이감을 가질 필요가 있다. 요소 영상을 픽업할 때 디지털 컴퓨터를 이용한 synthetic aperture integral imaging(SAII)이 채택되었다. 컴퓨터(Computational) II에서는 복원 면의 위치에 따라 복원되는 영상의 촛첨이 맺히는 영역이 달라진다. 심하게 은폐된 물체 영상의 복원은 은폐 물체의 블러링(bluring) 효과가 복원 면에 전체적으로 크게 나타나기 때문에 선명한 복원을 할 수가 없다. 이러한 은폐물의 블러링 효과가 제거된 복원 영상을 얻기 위해 분산 추정이라는 통계적인 방법이 채택되었다.

• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.56-65
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• 2009

Compton imaging is often recognized as a potentially more valuable 3-D technique in nuclear medicine than conventional emission tomography. Due to inherent computational limitations, however, it has been of a difficult problem to reconstruct images with good accuracy. In this work we show that the row-action maximum likelihood algorithm (RAMLA), which have proven useful for conventional tomographic reconstruction, can also be applied to the problem of 3-D reconstruction of cone-beam projections from Compton scattered data. The major advantage of RAMLA is that it converges to a true maximum likelihood solution at an order of magnitude faster than the standard expectation maximiation (EM) algorithm. For our simulations, we first model a Compton camera system consisting of the three pairs of scatterer and absorber detectors placed at x-, y- and z-axes, and generate conical projection data using a software phantom. We then compare the quantitative performance of RAMLA and EM reconstructions in terms of the percentage error. The net conclusion based on our experimental results is that the RAMLA applied to Compton camera reconstruction significantly outperforms the EM algorithm in convergence rate; while computational costs of one iteration of RAMLA and EM are about the same, one iteration of RAMLA performs as well as 128 iterations of EM.

• Archives of Plastic Surgery
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• 제47권6호
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• pp.590-596
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• 2020

Background The introduction of the partial second toe pulp free flap has enabled superior aesthetic and functional results for fingertip reconstruction in adults. Children undergoing fingertip amputation for various reasons have limited options for reconstruction. Conventional treatment could shorten the finger, leading to poor cosmesis and function. We report 18 years of our experiences with fingertip reconstruction using partial second toe pulp free flaps in patients in early childhood. Methods Medical charts of children who had undergone fingertip reconstruction using partial second toe pulp free flaps from 2001 to 2018 were retrospectively reviewed. The surgical procedures were identical to those for adults, except for the usage of 11-0 nylon sutures. Patients' demographic data, vessel size, flap dimensions, length of the distal phalanx, and functional outcomes over the course of long-term follow-up were documented. The statistical analysis was performed with the Student t-test, the Mann-Whitney U test, and Pearson correlation analysis. Results Eighteen toe pulp flaps in 17 patients (mean age, 3.0 years) were identified. All the flaps survived without any major complications. In long-term follow-up, the flap-covered distal phalanges showed growth in line with regular development. There was no donor-site morbidity, and all children adapted to daily life without any problems. In two-point discrimination tests, the fingertip sensation recovered to almost the same level as that in the contralateral finger. Conclusions Partial second toe pulp free flaps are an excellent option for fingertip reconstruction in young children, as well as in adults.

• 대한의용생체공학회:의공학회지
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• 제19권2호
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• pp.133-142
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• 1998

Bayesian SPECT 영상재구성에 있어서 정교한 형태의 사전정보를 사용할 경우 bias 및 variance와 같은 통계적 차원에서의 정량적 성능을 향상시킬 수 있다. 특히, "thin plate" 와 같은 고차의 smoothing 사전정보는 "membrane"과 같은 일반적인 다른 사전 정보에 비해 bias를 개선시키는 것으로 알려져 있다. 그러나, 이와 같은 장점은 영상재구성 알고리즘에 내재하는 hyperparameters의 값을 최적으로 선택하였을 경우에만 적용된다. 본 연구에서는 thin plate와 membrane의 두가지 대표적인 사전정보를 포함하는 영상재구성 알고리즘의 정량적 성능에 대해 집중 고찰한다. 즉, 알고리즘에 내재하는 hyperparameters 가 통계적 차원에서 bias와 variance에 어떠한 영향을 미치는지 관찰한다. 실험에서 Monte Carlo noise trials를 사용하여 bias와 variance를 계산하며, 각 결과를 ML-EM 및 filtered backprojection으로부터 얻어진 bias 및 variance와 비교한다. 결론적으로 thin plate와 같은 고차의 사전정보는 hyperparameters의 선택에 민감하지 않으며, hyperparameters 값의 전 범위에 걸쳐 bias를 개선시킴을 보인다. 걸쳐 bias를 개선시킴을 보인다.

• Journal of Gastric Cancer
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• 제22권2호
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• pp.83-93
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• 2022

Background: To analyze the short- and long-term clinical outcomes of 2 reconstruction methods after distal gastrectomy for gastric cancer. Methods: Three keywords, "gastric neoplasm," "distal gastrectomy," and "reconstruction," were used to search PubMed. We selected only randomized controlled trial that compared the anastomosis methods. A total of 11 papers and 8 studies were included in this meta-analysis. All statistical analyses were performed using the R software. Results: Among short-term clinical outcomes, a shorter operation time, reduced morbidity, and shorter hospital stay were found for Billroth type I (B-I) than for Roux-en-Y (RNY) reconstruction in the meta-analysis (P<0.001, P=0.048, P<0.001, respectively). When comparing Billroth type II (B-II) to RNY, the operation time was shorter for B-II than for RNY (P<0.019), but there were no differences in morbidity or length of hospital stay (P=0.500, P=0.259, respectively).Regarding long-term clinical outcomes related to reflux, there were significantly fewer incidents of reflux esophagitis, reflux gastritis, and bile reflux (P=0.035, P<0.001, P=0.019, respectively) for RNY than for B-I in the meta-analysis, but there was no difference between the 2 methods in residual food (P=0.545). When comparing B-II to RNY, there were significantly fewer incidents of reflux gastritis (P<0.001) for RNY than for B-II, but the amount of residual food and patient weight gain showed no difference. Conclusion: B-I had the most favorable short-term outcomes, but RNY was more advantageous for long-term outcomes than for other methods. Surgeons should be aware of the advantages and disadvantages of each type of anastomosis and select the appropriate method.