• Title/Summary/Keyword: statistical potential

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USING AN ABSTRACTION OF AMINO ACID TYPES TO IMPROVE THE QUALITY OF STATISTICAL POTENTIALS FOR PROTEIN STRUCTURE PREDICTION

  • Lee, Jin-Woo
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.15 no.3
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    • pp.191-199
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    • 2011
  • In this paper, we adopt a position specific scoring matrix as an abstraction of amino acid type to derive two new statistical potentials for protein structure prediction, and investigated its effect on the quality of the potentials compared to that derived using residue specific amino acid identity. For stringent test of the potential quality, we carried out folding simulations of 91 residue A chain of protein 2gpi, and found unexpectedly that the abstract amino acid type improved the quality of the one-body type statistical potential, but not for the two-body type statistical potential which describes long range interactions. This observation could be effectively used when one develops more accurate potentials for structure prediction, which are usually involved in merging various one-body and many-body potentials.

Statistical Back Trajectory Analysis for Estimation of CO2 Emission Source Regions (공기괴 역궤적 모델의 통계 분석을 통한 이산화탄소 배출 지역 추정)

  • Li, Shanlan;Park, Sunyoung;Park, Mi-Kyung;Jo, Chun Ok;Kim, Jae-Yeon;Kim, Ji-Yoon;Kim, Kyung-Ryul
    • Atmosphere
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    • v.24 no.2
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    • pp.245-251
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    • 2014
  • Statistical trajectory analysis has been widely used to identify potential source regions for chemically and radiatively important chemical species in the atmosphere. The most widely used method is a statistical source-receptor model developed by Stohl (1996), of which the underlying principle is that elevated concentrations at an observation site are proportionally related to both the average concentrations on a specific grid cell where the observed air mass has been passing over and the residence time staying over that grid cell. Thus, the method can compute a residence-time-weighted mean concentration for each grid cell by superimposing the back trajectory domain on the grid matrix. The concentration on a grid cell could be used as a proxy for potential source strength of corresponding species. This technical note describes the statistical trajectory approach and introduces its application to estimate potential source regions of $CO_2$ enhancements observed at Korean Global Atmosphere Watch Observatory in Anmyeon-do. Back trajectories are calculated using HYSPLIT 4 model based on wind fields provided by NCEP GDAS. The identified $CO_2$ potential source regions responsible for the pollution events observed at Anmyeon-do in 2010 were mainly Beijing area and the Northern China where Haerbin, Shenyang and Changchun mega cities are located. This is consistent with bottom-up emission information. In spite of inherent uncertainties of this method in estimating sharp spatial gradients within the vicinity of the emission hot spots, this study suggests that the statistical trajectory analysis can be a useful tool for identifying anthropogenic potential source regions for major GHGs.

Reproducibility of Statistical Motor Unit Number Estimate in Amyotrophic Lateral Sclerosis: Comparisons between Size-and Number-Weighted Modifications (근위축성 측삭 경화증에서의 Statistical Motor Unit Number Estimate 재연성: Size-and Number-Weighted Modifications간의 비교)

  • Kwon, Oh Yun;Lee, Kwang-Woo
    • Annals of Clinical Neurophysiology
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    • v.5 no.1
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    • pp.27-33
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    • 2003
  • Background: Motor unit number estimation (MUNE) can directly assess motor neuron populations in muscle and quantify the degree of physiologic and/or pathologic motor neuron degeneration. A high degree of reproducibility and reliability is required from a good quantitative tool. MUNE, in various ways, is being increasingly applied clinically and statistical MUNE has several advantages over alternative techniques. Nevertheless, the optimal method of applying statistical MUNE to improve reproducibility has not been established. Methods: We performed statistical MUNE by selecting the most compensated compound muscle action potential (CMAP) area as a test area and modified the results obtained by weighted mean surface-recorded motor unit potential (SMUP). Results: MUNE measures in amyotrophic lateral sclerosis (ALS) patients showed better reproducibility with sizeweighted modification. Conclusions: We suggest size-weighted MUNE testing of "neurogenically compensated"CMAP areas present an optimal method for statistical MUNE in ALS patients.

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Statistical analysis of direct current potential drop data (직류전위차법 자료에 대한 통계적 자료분석)

  • Lee, Jeong-Hee;Lee, Woo-Dong
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.1
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    • pp.139-146
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    • 2010
  • It was verified that the effect of the distance between current input point and output point on direct current potential drop (DCPD) in the material with two-dimensional surface notch. If the distance between potential drop measuring points was fixed at a certain distance, the potential drop was decreased with increasing the distance between current input and output points. DCPD technique was a useful method for surface crack sizing because the potential drop was proportional to the length of notch. In this paper, we suggest a statistical model to describe the data and want to find a significant variables to effect to potential drop. We use R program to analyze the data.

Evaluation of High Order Statistical Parameter for Electrochemical Noise Analysis

  • Kim, Jong Jip
    • Corrosion Science and Technology
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    • v.7 no.5
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    • pp.296-299
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    • 2008
  • High order statistical parameters were evaluated using the electrochemical noise data collected during corrosion of type 430 stainless steel coupled to a inert, platinum electrode in 3.5% NaCl solution. High order statistical parameters are shown to predict uniform corrosion properly. However, Localization index, skewness of current, kurtosis and skewness of potential are capable of predicting pitting corrosion only when the transients are large with long life time. Of the high order statistical parameters evaluated, kurtosis of current is found to be the most sensitive parameter for detecting uniform and pitting corrosion.

An analysis of the potential impact of various ozone regulatory standards on mortality

  • Kim, Yong-Ku
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.1
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    • pp.125-136
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    • 2011
  • Ground-level ozone, an air pollutant that is monitored by the Environmental Protection Agency (EPA), damages human health by irritating the respiratory system, reducing lung function, damaging lung cells, and aggravating asthma and other chronic conditions. In March 2008, the EPA strengthened ozone standards by lowering acceptable limits from 84 parts per billion to 75 parts per billion. Here epidemiologic data is used to study the effects of ozone regulation on human health and assessed how various regulatory standards for ozone may affect nonaccidental mortality, including respiratory-related deaths during ozone season. The assessment uses statistical methods based on hierarchical Bayesian models to predict the potential effects of the different regulatory standards. It also analyzes the variability of the results and ho they are impacted by different modeling assumptions. We focused on the technical an statistical approach to assessing relationship between new ozone regulations and mortality while other researches have detailed the relationship between ozone and human mortality. We shows a statistical correlation between ozone regulations and mortality, with lower limits of acceptable ozone linked to a decrease in deaths, and projects that mortality is expected to decrease by reducing ozone regulatory standards.

Statistical Characterization Fabricated Charge-up Damage Sensor

  • Samukawa Seiji;Hong, Sang-Jeen
    • Transactions on Electrical and Electronic Materials
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    • v.6 no.3
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    • pp.87-90
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    • 2005
  • $SiO_2$ via-hole etching with a high aspect ratio is a key process in fabricating ULSI devices; however, accumulated charge during plasma etching can cause etching stop, micro-loading effects, and charge build-up damage. To alleviate this concern, charge-up damage sensor was fabricated for the ultimate goal of real-time monitoring of accumulated charge. As an effort to reach the ultimate goal, fabricated sensor was used for electrical potential measurements of via holes between two poly-Si electrodes and roughly characterized under various plasma conditions using statistical design of experiment (DOE). The successful identification of potential difference under various plasma conditions not only supports the evidence of potential charge-up damage, but also leads the direction of future study.

Survey of the use of statistical methods in Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • Choi, Yong-Geun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.44 no.1
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    • pp.25-28
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    • 2018
  • Objectives: This study aimed to describe recent patterns in the types of statistical test used in original articles that were published in Journal of the Korean Association of Oral and Maxillofacial Surgeons. Materials and Methods: Thirty-six original articles published in the Journal in 2015 and 2016 were ascertained. The type of statistical test was identified by one researcher. Descriptive statistics, such as frequency, rank, and proportion, were calculated. Graphical statistics, such as a histogram, were constructed to reveal the overall utilization pattern of statistical test types. Results: Twenty-two types of statistical test were used. Statistical test type was not reported in four original articles and classified as unclear in 5%. The four most frequently used statistical tests constituted 47% of the total tests and these were the chi-square test, Student's t-test, Fisher's exact test, and Mann-Whitney test in descending order. Regression models, such as the Cox proportional hazard model and multiple logistic regression to adjust for potential confounding variables, were used in only 6% of the studies. Normality tests, including the Kolmogorov-Smirnov test, Levene test, Shapiro-Wilk test, and $Scheff{\acute{e}}^{\prime}s$ test, were used diversely but in only 10% of the studies. Conclusion: A total of 22 statistical tests were identified, with four tests occupying almost half of the results. Adoption of a nonparametric test is recommended when the status of normality is vague. Adjustment for confounding variables should be pursued using a multiple regression model when the number of potential confounding variables is numerous.

Method-Free Permutation Predictor Hypothesis Tests in Sufficient Dimension Reduction

  • Lee, Kyungjin;Oh, Suji;Yoo, Jae Keun
    • Communications for Statistical Applications and Methods
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    • v.20 no.4
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    • pp.291-300
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    • 2013
  • In this paper, we propose method-free permutation predictor hypothesis tests in the context of sufficient dimension reduction. Different from an existing method-free bootstrap approach, predictor hypotheses are evaluated based on p-values; therefore, usual statistical practitioners should have a potential preference. Numerical studies validate the developed theories, and real data application is provided.

A Geo-statistical Assessment of Heavy Metal Pollution in the Soil Around a Ship Building Yard in Busan, Korea (통계지표를 활용한 부산지역 조선소 주변 토양 내 중금속 오염조사 연구)

  • Choi, Jung-Sik;Jeon, Soo kyung
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.7
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    • pp.907-915
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    • 2018
  • With the increase of metal usage in various industries, metal pollution and ecological toxicity in the environmental system have become a significant concern. A geo-statistical index has been widely used to determine contamination level with normalization through a background value. In this study, geo-statistical indexes such as an enrichment factor, accumulation index, and potential ecological risk index were used to assess metal pollution in soil at locations associated with shipbuilding manufacturing industries. Metal contamination, especially of Cu and Pb, was observed in some samples located closer to manufacturing sites. Enrichment factor and accumulation (IGEO) values were indicative of concerning levels of soil contamination in specific samples, and the soil contamination could be induced by anthropogenic sources. In further study, after more detailed sampling for soil and potential pollution sources, high interpretation techniques such as Pb isotope analysis and X-ray analysis will be needed to investigate source identification.