• Journal of the Korean Statistical Society
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• 제9권1호
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• pp.97-108
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• 1980

Variance components model appears often in designing experiments including time series data analysis. This paper is investigating the properties of the various procedures in estimating variance components for the two-way random model without interaction under normality. In this age of computer-oriented computations, MINQUE is found to be quite practicla because of the robustness with respect to the design configurations and parameters. Also adjusted AOV type estimation procedure is found to yield superior results over the unadjusted one.

• 한국임상수의학회지
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• 제26권3호
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• pp.189-199
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• 2009

With the growing importance of evidence-based medicine, clinical or biomedical research relies critically on the validity and reliability of data, and the subsequent statistical inferences for medical decision-making may lead to valid conclusion. Despite widespread use of analytical techniques in papers published in the Journal of Veterinary Clinics statistical errors particularly in design of experiments, research methodology or data analysis methods are commonly encountered. These flaws often leading to misinterpretation of the data, thereby, subjected to inappropriate conclusions. This article is the first in a series of nontechnical introduction designed not to systemic review of medical statistics but intended to provide the journal readers with an understanding of common statistical concepts, including data scale, selection of appropriate statistical methods, descriptive statistics, data transformation, confidence interval, the principles of hypothesis testing, sampling distribution, and interpretation of results.

• Journal of applied mathematics & informatics
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• 제6권2호
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• pp.631-638
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• 1999

Sensitive testing has been widely employed for many years in connection with the development and evaluation explosives detonation devices and propellants. Perhaps its earliest and possibly most important implementation was in biological studies of dosage mortality and response to drugs. Recently sensitivity experiments has been employed in the evaluation of new materials subject to stress in various environments and in delineanation of unstable combustion regions in chemical propulsion systems. This paper discussed a sta-tistical development of sensitivity testing.

• 반도체디스플레이기술학회지
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• 제3권1호
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• pp.35-39
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• 2004

Statistical design of experiments was successfully employed to investigate the effect of alternating magnetic field on activation of polycrystalline Si (p-Si) doped as n-type using $\textrm{PH}_3$, by full factorial design of three factors with two levels. In this design, the input variables are graphite size, alternating current, and activation time. The output parameter, sheet resistance, is analyzed in terms of the primary effects and multi-factor interactions. Notably, the three-factor interaction is calculated to be a dominant interaction. The interaction between graphite size and activation time and the main effect of current are important effects compared to the other variables and relevant interactions. Alternating magnetic flux activation is proved a significantly beneficial processing technique.

• Transactions on Electrical and Electronic Materials
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• 제13권3호
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• pp.129-135
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• 2012

A number of surface mount technology (SMT) process variables including land design are considered for minimizing tombstone defect in flexible printed circuit assembly in high volume manufacturing. As SMT chip components have been reduced over the past years with their weights in milligrams, the torque that once helped self-centering of chips, gears to tombstone defects. In this paper, we have investigated the correlation of the assembly process variables with respect to the tombstone defect by employing statistically designed experiment. After the statistical analysis is performed, we have setup hypotheses for the root causes of tombstone defect and derived main effects and interactions of the process parameters affecting the hypothesis. Based on the designed experiments, statistical analysis was performed to investigate significant process variable for the purpose of process control in flexible printed circuit manufacturing area. Finally, we provide beneficial suggestions for find-pitch PCB design, screen printing process, chip-mounting process, and reflow process to minimize the tombstone defects.

• 상하수도학회지
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• 제19권2호
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• pp.181-192
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• 2005

This study evaluated the effect of factors influencing the initial biofilm formation in drinking water distribution pipe by running experiments using a $2^{4-1}$ fractional factorial experimental design with a replicate. Important variables used for assessing biofilm formation included BDOC(biodegradable dissolved organic carbon), viable heterotrophic bacteria present in drinking water, water temperature, and shear stress at two levels each. Based on the statistical analysis of biofilm levels measured as attached HPC(heterotrophic plate count) and community-level assay, the main factors that have significant effects on biofilm formation were found to be viable heterotrophic bacteria and BDOC. Water temperature only exhibited significant effect on the levels of attached HPC, while shear stress was not a significant factor under given conditions. Moreover, the statistical analysis revealed that interactions between the important variables were not statistically significant at a 0.05 significance level.

• 응용통계연구
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• 제17권3호
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• pp.419-430
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• 2004

마이크로어레이 기술은 한번에 수만 개의 유전자를 동시에 분석할 수 있는 고효율, 고가의 새로운 연구 도구로 자리잡았으며 마이크로어레이 실험 자료의 올바른 분석을 위해서는 실험 목적에 맞는 실험계획법의 확립과 통계분석법의 적용이 중요하다 본 논문에서는 마이크로어레이 자료에서 여러 군 사이에서 발현의 차이를 보이는 유전자를 찾을 수 있는 되돌림 설계를 소개하고 ANOVA 모형을 이용하여 분석하는 방법을 제시한다. 연세대학교 암전이 연구센터의 되돌림 설계를 이용한 백혈병 자료를 MA-ANOVA(Wu et. al.(2003))를 이용하여 분석하였다

• Corrosion Science and Technology
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• 제12권3호
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• pp.132-141
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• 2013

This work is concerning a methodology of Ni-base superalloy development for a very high temperature gas-cooled reactor(VHTR) using design of experiments(DOE) and thermodynamic calculations. Total 32 sets of the Ni-base superalloys with various chemical compositions were formulated based on a fractional factorial design of DOE, and the thermodynamic stability of topologically close-packed(TCP) phases of those alloys was calculated by using the THERMO-CALC software. From the statistical evaluation of the effect of the chemical composition on the formation of TCP phase up to a temperature of 950 oC, which should be suppressed for prolonged service life when it used as the structural components of VHTR, 16 sets were selected for further calculation of the mechanical properties. Considering the yield and ultimate tensile strengths of the selected alloys estimated by using the JMATPRO software, the optimized chemical composition of the alloys for VHTR application, especially intermediate heat exchanger, was proposed for a succeeding experimental study.

• 응용통계연구
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• 제27권6호
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• pp.1029-1038
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• 2014

본 연구에서는 베이지안 실험계획법에 대하여 논의하고 간단한 모의실험을 통하여 최적화된 베이지안 실험계획법이 어떠한 특징을 가지고 있는지 설명하였다. 실험을 설계하는 경우 연구자는 관심있는 주제가 모수추정인지 아니면 예측인지를 결정하고 사전확률과 우도함수를 기반으로 이에 맞는 사후확률을 찾아 효용함수와 결합하여 최적의 실험설계를 찾는 것이 베이지안 실험계획법의 기본 원리이다. 만일 사전적 정보가 존재하지 않는다면 무정보적 부적합 사전확률을 이용하여 실험을 설계할 수 있으며, 이는 비 베이지안적 접근방법과 일치하게 된다. 만일 모수나 예측값에 대한 사전적 정보가 존재하는 경우에는 베이지안 실험계획법이 유일한 해결 방법이다. 하지만 모형의 복잡도가 증가하게 되면, 최적해를 찾는 과정이 매우 복잡해져서 극복해야 하는 많은 문제점들이 존재하므로 향후 많은 연구가 필요한 분야이다.

• 반도체디스플레이기술학회지
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• 제12권4호
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• pp.9-13
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• 2013

Lapping is a very complicated and random process resulting from the variation of abrasive grains in its sizes and shapes and from the numerous factors having an effect on the process quality. This paper presents a study of a $2^4$ full factorial experimental design and analysis to optimize surface quality in lapping operation. The optimization of the factors to obtain minimum surface roughness was carried out by incorporating effect plots, main effect plots, interaction plots, analysis of variance(ANOVA), surface plots, and contour plots. The statistical design experiments, designed to reduce the total number of experiments required, indicated that, within the selected conditions, all the parameters influenced at a significance level of 5%. In addition, some of the possible interactions between these parameters also influenced the lapping process, especially those that were of third order. A regression model was suggested and fitted the experimental data very well.