• 제목/요약/키워드: statistical design of experiments

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Guidelines for experimental design and statistical analyses in animal studies submitted for publication in the Asian-Australasian Journal of Animal Sciences

  • Seo, Seongwon;Jeon, Seoyoung;Ha, Jong K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권9호
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    • pp.1381-1386
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    • 2018
  • Animal experiments are essential to the study of animal nutrition. Because of the large variations among individual animals and ethical and economic constraints, experimental designs and statistical analyses are particularly important in animal experiments. To increase the scientific validity of the results and maximize the knowledge gained from animal experiments, each experiment should be appropriately designed, and the observations need to be correctly analyzed and transparently reported. There are many experimental designs and statistical methods. This editorial does not aim to review and present particular experimental designs and statistical methods. Instead, we discuss some essential elements when designing an animal experiment and conducting statistical analyses in animal nutritional studies and provide guidelines for submitting a manuscript to the Asian-Australasian Journal of Animal Sciences for consideration for publication.

실험계획법을 이용한 MOF-5 합성공정 최적화 연구 (A Study of the Optimization of the MOF-5 Synthesis Process using Design of Experiments)

  • 이민형;이상민;유계상
    • 공업화학
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    • 제33권4호
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    • pp.402-407
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    • 2022
  • 실험계획법을 이용하여 MOF-5 합성공정의 최적화에 대한 연구를 수행하였다. 먼저 전구체의 농도를 최적화 하기 위하여 혼합물 설계법을 이용하였다. 합성에 사용되는 세 가지 전구체인 terephthalic acid, zinc acetate dihydrate, N,N-dimethylformamide의 농도비를 extreme vertices design methods로 최적화 하였다. MOF-5 합성을 위한 최적의 농도는 1 mol : 2.7 mol : 40 mol로 예측되었다. 이후, 온도, 시간 및 교반 속도와 같은 합성 반응 조건이 합성에 미치는 영향을 분석하기 위해 다단계 요인 설계법을 사용하였다. 수행된 통계 분석에 따라 교반 속도는 후속 연구에서 제외되었다. 합성시간과 온도를 고려한 합성 공정 최적화는 중앙 조성 설계법을 이용하였다. 13번의 합성 실험을 통해 도출된 2차 모델 방정식을 이용하여 결과를 추정하였다. 설계에 사용된 모델에 의하면 119 ℃ 및 10.4 h 조건에서 합성된 MOF-5가 최대의 결정화도를 가지는 것으로 예측되었다.

3n-p Fractional Factorial Design Excluded Some Debarred Combinations

  • Park, Byoung -Chul
    • Communications for Statistical Applications and Methods
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    • 제6권3호
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    • pp.695-706
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    • 1999
  • When fractional factorial experiments contain some infeasible treatment combinations called debarred combinations we should construct experimental designs so that those debarred combinations are to be excluded by selecting defining contrasts appropriately. By applying Franklin(1995)'s procedure for selecting defining contrasts to Cheng and Li(1993)'s method this paper presents a method of selecting defining contrasts to construct orthogonal 3-level fractional factorial experiments which exclude some debarred combinations.

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다양한 런 규칙을 고려한 VSI 관리도의 경제적-통계적 설계 (Economic-statistical Design of VSI Control Charts Considering Various Runs Rules)

  • 강분규;임태진
    • 한국품질경영학회:학술대회논문집
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    • 한국품질경영학회 2010년도 춘계학술대회
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    • pp.123-128
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    • 2010
  • This article investigates economic-statistical design of VSI(variable samling interval) charts considering Various Runs Rules. Most recent adaptive control charts are conplex designs. Actually It's not easy to operating control quality process. We propose a procedure for designing VSI Runs charts, based on Lorenzen and Vence's model. The optimal design parameters of the charts can be determined by minimizing the cost model. And computational experiments show that the VSI Runs Rules charts is superior to the FSSI Runs Rules charts in the economic-statistical characterisitics.

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순차적 실험계획법과 인공신경망을 이용한 제한조건이 없는 문제의 최적화 알고리즘 개발 (Development of Optimization Algorithm for Unconstrained Problems Using the Sequential Design of Experiments and Artificial Neural Network)

  • 이정환;서명원
    • 대한기계학회논문집A
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    • 제32권3호
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    • pp.258-266
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    • 2008
  • The conventional approximate optimization method, which uses the statistical design of experiments(DOE) and response surface method(RSM), can derive an approximated optimum results through the iterative process by a trial and error. The quality of results depends seriously on the factors and levels assigned by a designer. The purpose of this study is to propose a new technique, which is called a sequential design of experiments(SDOE), to reduce a trial and error procedure and to find an appropriate condition for using artificial neural network(ANN) systematically. An appropriate condition is determined from the iterative process based on the analysis of means. With this new technique and ANN, it is possible to find an optimum design accurately and efficiently. The suggested algorithm has been applied to various mathematical examples and a structural problem.

Robust Designs to Outliers for Response Surface Experiments

  • Jeong B. Yoo;Park, Sung H.
    • Journal of the Korean Statistical Society
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    • 제20권2호
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    • pp.147-155
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    • 1991
  • This paper treats a robust design criterion which minimizes the effects of outliers and model inadequacy, and investigates robust designs for some response surface designs. In order to develop a robust design criterion and robust design, the integrated mean squared error of *(equation omitted) over a region is utilized, where *(equation omitted). is the estimated response by the minimum bias estimation proposed by carson, Manson and Hader (1969) . According to the number of aberrant observations and their positions, the proposed criterion and designs are studied. Also further development of the proposed criterion is treated when outliers can occur in any position of a design.

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Slope-rotatable Designs for Estimating the Slope of Response Surfaces in Experiments with Mixtures

  • Park, Sung H.;Kim, Jung I.
    • Journal of the Korean Statistical Society
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    • 제17권2호
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    • pp.121-133
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    • 1988
  • In this paper a class of mixture designs for estimating the slope of second order Scheffe polynomial response surfaces for mixture experiments with q components is presented. The variance of the estimated directional slope at a point is a function of the direction of the slope and the design. If the variance is averaged over all possible directions in the (q-1)-dimensional simplex, the averaged variance is only a function of the point and the design. By choice of design, it is possible to make this variance constant for all points equidistant from the centroid point. This property is called "slope-rotatability over al directions in the simplex", and the necessary and sufficient conditions for mixture design to have this property are given and proved. The class of designs with this property is compared with other mixture designs and discussed.discussed.

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반응표면을 활용한 통계적 모멘트 추정 방법과 신뢰도해석에 적용 (RS-based method for estimating statistical moments and its application to reliability analysis)

  • 허재성;곽병만
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.852-857
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    • 2004
  • A new and efficient method for estimating the statistical moments of a system performance function has been developed. The method consists of two steps: (1) An approximate response surface is generated by a quadratic regression model, and (2) the statistical moments of the regression model are then calculated by experimental design techniques proposed by Seo and $Kwak^{(4)}$. In this approach, the size of experimental region affects the accuracy of the statistical moments. Therefore, the region size should be selected suitably. The D-optimal design and the central composite design are adopted over the selected experimental region for the regression model. Finally, the Pearson system is adopted to decide the distribution type of the system performance function and to analyze structural reliability.

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적응형 이동평균(A-MA) 관리도의 경제적-통계적 설계 (Economic-Statistical Design of Adaptive Moving Average (A-MA) Control Charts)

  • 임태진
    • 대한산업공학회지
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    • 제34권3호
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    • pp.328-336
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    • 2008
  • This research proposes a method for economic-statistical design of adaptive moving average (A-MA) charts. The basic idea of the A-MA chart is to accumulate previous samples selectively in order to increase the sensitivity. The A-MA chart is a kind of adaptive chart such as the variable sampling size (VSS) chart. A major advantage of the A-MA chart over the VSS chart is that it is easy to maintain rational subgroups by using the fixed sampling size. A steady state cost rate function is constructed based on Lorenzen and Vance (1986) model. The cost rate function is optimized with respect to five design parameters. Computational experiments show that the A-MA chart is superior to the VSS chart as well as to the Shewhart $\bar{X}$ chart in the economic-statistical sense.

Review on the Application of Statistical Methods to Maritime Traffic Safety Assessment

  • Gong, In-Young
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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    • pp.35-40
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    • 2006
  • For the maritime traffic safety assessment of vessels navigating in harbor or fairway, simulation techniques by using shiphandling simulator system have been traditionally used. When designing the simulation experiments and when analyzing the simulation results, however, there has been a little systematic method. Ship-handling simulations can be regarded as a kind of statistical experiment by using ship-handling simulator system, which means that shiphandling simulation conditions should be designed statistically and that the simulation results should be statistically analyzed as well. For the safe and economic design of harbor and fairway, reasonable decisions based upon the scientific analysis of shiphandling simulation results are indispensable. In this paper, various statistical methods, such as Bayes theorem, statistical hypothesis testing, and probability distributions, are reviewed with a view to application to maritime traffic safety assessment. It is expected that more reasonable decisions on harbor and fairway design can be made from shiphandlers' view point by using statistical methods.

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