• Title/Summary/Keyword: statistical assessment

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Evaluating the Reliability of Short-Form Berg Balance Scales and Short-Form Postural Assessment Scales in Chronic Stroke Survivors

  • Seung-Heon An;Dae-Sung Park
    • Physical Therapy Rehabilitation Science
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    • v.13 no.2
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    • pp.143-151
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    • 2024
  • Objective: This study aims to assess the test-retest reproducibility of the Short Form Berg Balance Scale (SF-BBS) and the Short Form Postural Assessment Scale for Stroke (SF-PASS) among chronic stroke survivors, focusing on their reliability for consistent measurements over time. Design: A cross-sectional study design Methods: Thirty chronic stroke survivors participated in this study, undergoing evaluations with SF-BBS and SF-PASS scales at two different points, separated by a seven-day interval. The analysis focused on test-retest reliability, employing statistical measures such as the Intra-Class Coefficient (ICC2,1), Standard Error of Measurement (SEM), Minimal Detectable Change (MDC), and MDC%, the Bland-Altman plot to assess the limits of agreement and the extent of random measurement error. Results: The study found notable test-retest reproducibility for both SF-BBS and SF-PASS, with ICC values demonstrating strong reliability (0.932 to 0.941, with a confidence interval of 0.889 to 0.973). SEM values for SF-BBS and SF-PASS were reported as 1.34 and 0.61, respectively, indicating low measurement error. MDC values of 3.71 for SF-BBS and 1.69 for SF-PASS suggest that the scales have an acceptable level of sensitivity to change, with reliability metrics falling below 20% of the maximum possible score. Conclusions: The findings suggest that both SF-BBS and SF-PASS exhibit high intra-class correlation coefficients, indicating strong test-retest reliability. The SEM and MDC values further support the scales' reproducibility and reliability as tools for evaluating mobility and dynamic balance in chronic stroke survivors. Therefore, these scales are recommended for clinical use in this population, providing reliable measures for assessing progress in rehabilitation.

Lifespan assessment of piezoelectric sensors under disposal condition of high-level nuclear waste repository

  • Changhee Park;Hyun-Joong Hwang;Chang-Ho Hong;Jin-Seop Kim;Gye-Chun Cho
    • Geomechanics and Engineering
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    • v.38 no.5
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    • pp.529-539
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    • 2024
  • A high-level nuclear waste (HLW) repository is designed for the long-term disposal of high-level waste. Positioned at depths of 500-1000 meters, it offers an alternative to the insufficient storage space for spent fuels, providing a long-term solution. High-level waste emits heat and radiation, causing structural deterioration, including strength reduction and cracks. Therefore, the use of piezoelectric sensors for structural health monitoring is essential for evaluating the safety of the structure over time. Unlike other structures, the HLW repository restricts human access after the disposal of HLW, rendering sensor replacement impossible. Therefore, it is necessary to assess both the lifespan and suitability of sensors under the disposal conditions in the HLW repository. This study employed an accelerated life test (ALT) to assess the sensor's lifespan under disposal conditions. Failure modes, failure mechanisms, and operational limits were analyzed through accelerated stress test (AST). Additionally, the parameters of the Weibull life probability distribution and the Arrhenius accelerated life model were estimated through statistical methods, including the likelihood ratio test, maximum likelihood estimation, and hypothesis testing. Results confirmed that the sensor's lifespan decreases significantly with the increase in the temperature limit of the HLW repository. The findings of this study can be used for improving sensor lifespan through shielding, development of alternative sensors, or lifespan evaluation of alternative monitoring sensors.

Development and validation of novel simple prognostic model for predicting mortality in Korean intensive care units using national insurance claims data

  • Ah Young Leem;Soyul Han;Kyung Soo Chung;Su Hwan Lee;Moo Suk Park;Bora Lee;Young Sam Kim
    • The Korean journal of internal medicine
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    • v.39 no.4
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    • pp.625-639
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    • 2024
  • Background/Aims: Intensive care unit (ICU) quality is largely determined by the mortality rate. Therefore, we aimed to develop and validate a novel prognostic model for predicting mortality in Korean ICUs, using national insurance claims data. Methods: Data were obtained from the health insurance claims database maintained by the Health Insurance Review and Assessment Service of South Korea. From patients who underwent the third ICU adequacy evaluation, 42,489 cases were enrolled and randomly divided into the derivation and validation cohorts. Using the models derived from the derivation cohort, we analyzed whether they accurately predicted death in the validation cohort. The models were verified using data from one general and two tertiary hospitals. Results: Two severity correction models were created from the derivation cohort data, by applying variables selected through statistical analysis, through clinical consensus, and from performing multiple logistic regression analysis. Model 1 included six categorical variables (age, sex, Charlson comorbidity index, ventilator use, hemodialysis or continuous renal replacement therapy, and vasopressor use). Model 2 additionally included presence/absence of ICU specialists and nursing grades. In external validation, the performance of models 1 and 2 for predicting in-hospital and ICU mortality was not inferior to that of pre-existing scoring systems. Conclusions: The novel and simple models could predict in-hospital and ICU mortality and were not inferior compared to the pre-existing scoring systems.

Multivariate Analysis of Predictive Factors for the Severity in Stable Patients with Severe Injury Mechanism (중증 손상 기전의 안정된 환자에서 중증도 예측 인자들에 대한 다변량 분석)

  • Lee, Jae Young;Lee, Chang Jae;Lee, Hyoung Ju;Chung, Tae Nyoung;Kim, Eui Chung;Choi, Sung Wook;Kim, Ok Jun;Cho, Yun Kyung
    • Journal of Trauma and Injury
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    • v.25 no.2
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    • pp.49-56
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    • 2012
  • Purpose: For determining the prognosis of critically injured patients, transporting patients to medical facilities capable of providing proper assessment and management, running rapid assessment and making rapid decisions, and providing aggressive resuscitation is vital. Considering the high mortality and morbidity rates in critically injured patients, various studies have been conducted in efforts to reduce those rates. However, studies related to diagnostic factors for predicting severity in critically injured patients are still lacking. Furthermore, patients showing stable vital signs and alert mental status, who are injured via a severe trauma mechanism, may be at a risk of not receiving rapid assessment and management. Thus, this study investigates diagnostic factors, including physical examination and laboratory results, that may help predict severity in trauma patients injured via a severe trauma mechanism, but showing stable vital signs. Methods: From March 2010 to December 2011, all trauma patients who fit into a diagnostic category that activated a major trauma team in CHA Bundang Medical Center were analyzed retrospectively. The retrospective analysis was based on prospective medical records completed at the time of arrival in the emergency department and on sequential laboratory test results. PASW statistics 18(SPSS Inc., Chicago, IL, USA) was used for the statistical analysis. Patients with relatively stable vital signs and alert mental status were selected based on a revised trauma score of more than 7 points. The final diagnosis of major trauma was made based on an injury severity score of greater than 16 points. Diagnostic variables include systolic blood pressure and respiratory rate, glasgow coma scale, initial result from focused abdominal sonography for trauma, and laboratory results from blood tests and urine analyses. To confirm the true significance of the measured values, we applied the Kolmogorov-Smirnov one sample test and the Shapiro-Wilk test. When significance was confirmed, the Student's t-test was used for comparison; when significance was not confirmed, the Mann-Whitney u-test was used. The results of focused abdominal sonography for trauma (FAST) and factors of urine analysis were analyzed using the Chi-square test or Fisher's exact test. Variables with statistical significance were selected as prognostics factors, and they were analyzed using a multivariate logistics regression model. Results: A total of 269 patients activated the major trauma team. Excluding 91 patients who scored a revised trauma score of less than 7 points, 178 patients were subdivided by injury severity score to determine the final major trauma patients. Twenty-one(21) patients from 106 major trauma patients and 9 patients from 72 minor trauma patients were also excluded due to missing medical records or untested blood and urine analysis. The investigated variables with p-values less than 0.05 include the glasgow coma scale, respiratory rate, white blood cell count (WBC), serum AST and ALT, serum creatinine, blood in spot urine, and protein in spot urine. These variables could, thus, be prognostic factors in major trauma patients. A multivariate logistics regression analysis on those 8 variables showed the respiratory rate (p=0.034), WBC (p=0.005) and blood in spot urine (p=0.041) to be independent prognostic factors for predicting the clinical course of major trauma patients. Conclusion: In trauma patients injured via a severe trauma mechanism, but showing stable vital signs and alert mental status, the respiratory rate, WBC count and blood in the urine can be used as predictable factors for severity. Using those laboratory results, rapid assessment of major trauma patients may shorten the time to diagnosis and the time for management.

A Study on Risk Assessment Method for Earthquake-Induced Landslides (지진에 의한 산사태 위험도 평가방안에 관한 연구)

  • Seo, Junpyo;Eu, Song;Lee, Kihwan;Lee, Changwoo;Woo, Choongshik
    • Journal of the Society of Disaster Information
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    • v.17 no.4
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    • pp.694-709
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    • 2021
  • Purpose: In this study, earthquake-induced landslide risk assessment was conducted to provide basic data for efficient and preemptive damage prevention by selecting the erosion control work before the earthquake and the prediction and restoration priorities of the damaged area after the earthquake. Method: The study analyzed the previous studies abroad to examine the evaluation methodology and to derive the evaluation factors, and examine the utilization of the landslide hazard map currently used in Korea. In addition, the earthquake-induced landslide hazard map was also established on a pilot basis based on the fault zone and epicenter of Pohang using seismic attenuation. Result: The earthquake-induced landslide risk assessment study showed that China ranked 44%, Italy 16%, the U.S. 15%, Japan 10%, and Taiwan 8%. As for the evaluation method, the statistical model was the most common at 59%, and the physical model was found at 23%. The factors frequently used in the statistical model were altitude, distance from the fault, gradient, slope aspect, country rock, and topographic curvature. Since Korea's landslide hazard map reflects topography, geology, and forest floor conditions, it has been shown that it is reasonable to evaluate the risk of earthquake-induced landslides using it. As a result of evaluating the risk of landslides based on the fault zone and epicenter in the Pohang area, the risk grade was changed to reflect the impact of the earthquake. Conclusion: It is effective to use the landslide hazard map to evaluate the risk of earthquake-induced landslides at the regional scale. The risk map based on the fault zone is effective when used in the selection of a target site for preventive erosion control work to prevent damage from earthquake-induced landslides. In addition, the risk map based on the epicenter can be used for efficient follow-up management in order to prioritize damage prevention measures, such as to investigate the current status of landslide damage after an earthquake, or to restore the damaged area.

Statistical Errors in Papers Published in the Journal of the Korean Society for Therapeutic Radiology and Oncology (대한방사선종양학회지 게재 논문의 통계적 오류 현황)

  • Park, Hee-Chul;Choi, Doo-Ho;Ahn, Song-Vogue;Kang, Jin-Oh;Kim, Eun-Seog;Park, Won;Ahn, Seung-Do;Yang, Dae-Sik;Yun, Hyong-Geun;Chung, Eun-Ji;Chie, Eui-Kyu;Pyo, Hong-Ryull;Hong, Se-Mie
    • Radiation Oncology Journal
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    • v.26 no.4
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    • pp.289-294
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    • 2008
  • Purpose: To improve the quality of the statistical analysis of papers published in the Journal of the Korean Society for Therapeutic Radiology and Oncology (JKOSTRO) by evaluating commonly encountered errors. Materials and Methods: Papers published in the JKOSTRO from January 2006 to December 2007 were reviewed for methodological and statistical validity using a modified version of Ahn's checklist. A statistician reviewed individual papers and evaluated the list items in the checklist for each paper. To avoid the potential assessment error by the statistician who lacks expertise in the field of radiation oncology; the editorial board of the JKOSTRO reviewed each checklist for individual articles. A frequency analysis of the list items was performed using SAS (version 9.0, SAS Institute, NC, USA) software. Results: A total of 73 papers including 5 case reports and 68 original articles were reviewed. Inferential statistics was used in 46 papers. The most commonly adopted statistical methodology was a survival analysis (58.7%). Only 19% of papers were free of statistical errors. Errors of omission were encountered in 34 (50.0%) papers. Errors of commission were encountered in 35 (51.5%) papers. Twenty-one papers (30.9%) had both errors of omission and commission. Conclusion: A variety of statistical errors were encountered in papers published in the JKOSTRO. The current study suggests that a more thorough review of the statistical analysis is needed for manuscripts submitted in the JKOSTRO.

A Study on the Effect of University Library User's Sense of Community on User Satisfaction and Loyalty (대학도서관 이용자의 공동체의식이 이용자 만족도 및 충성도에 미치는 영향 연구)

  • Roh, Hyo Jin;Chang, Woo Kwon
    • Journal of the Korean Society for information Management
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    • v.36 no.1
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    • pp.137-168
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    • 2019
  • This study measures and analyzes the university library user's sense of community, service quality assessment, user satisfaction and loyalty. In addition, the effect of the university library user's sense of community on university library user satisfaction and loyalty mediated by the assessment of the quality of service is investigated. On the basis of study result, to improve user satisfaction and user loyalty, the direction and implications of library development are presented. In order to achieve the purpose of the study, precedent research and literature were investigated, and the study model and hypothesis were established based on theoretical background. In order to verify the hypothesis, a total of 300 questionnaires were distributed to subject who had experience using the Central Library among undergraduate students at the C National University, and the final 282 sample was used for analysis. To analyze the differences depending on the general characteristics of the samples, It is the result of an independent sample t-test and one-way ANOVA. The results of the mediated effects analysis using the PROCESS macro-programs models 4 and 6 of Hayes for hypothesis testing are as follows. First, The university library user's sense of community (Service Benefits Perception and Satisfaction, Mutual sense of influence) effect the user satisfaction of university library mediated by service quality assessment at statistical significance. This showed that the higher the university library user's sense of community, the higher the service quality assessment, and the higher the user satisfaction level of university library. Second, The university library user's sense of community (Service Benefits Perception and Satisfaction, Mutual sense of influence) effect the user loyalty of university library mediated by service quality assessment and user satisfaction. This showed that the higher the university library user's sense of community, the higher the service quality assessment, the higher user satisfaction level of university library and the higher the user loyalty level of university library. The results of this study showed that the university library user's sense of community has a direct and indirect effect on enhancing user satisfaction and loyalty through the service quality assessment.

Individual Bioequivalence Tests under 3 X 2 Design (3 X 2 교차설계법에서 개인 생물학적 동등성 검정)

  • Jung, Gyu-Jin;Lim, Nam-Kyoo;Park, Sang-Gue
    • The Korean Journal of Applied Statistics
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    • v.23 no.1
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    • pp.139-150
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    • 2010
  • In recent years, more generic drug products became available. The current regulation for assessing the bioequivalence of two drug formulations is based on the concept of average bioequivalence. This approach has been indicated to be insufficient for assessing switchability between two drug formulations and US FDA has adopted individual bioequivalence as one of the bioequivalence criterion since 2001. The US FDA recommends that individual bioequivalence be assessed based on $2\;{\times}\;4$ crossover design, while a $2\;{\times}\;3$ crossover design may be used as an alternative design to reduce the length and cost of the study. In this paper, a statistical procedure for assessment of individual bioequivalence under $3\;{\times}\;2$ crossover designs is proposed and some statistical points are discussed with $2\;{\times}\;3$ crossover design and $2\;{\times}\;3$ extra-reference design through simulation studies.

Comparison of formaldehyde concentration in working environment between passive sampling method and impinger sampling method (능동포집법과 확산포집법에 의한 작업환경 중 포름알데히드 농도 비교)

  • Ham, Seong-Ae;Mun, Deok-Hwan
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.4
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    • pp.346-355
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    • 2006
  • The purpose of this study was conducted to ascertain the difference between impinger and passive sampling methods in the process of sampling and analyzing on airborne formaldehyde. Formaldehyde generating workplaces included in this study comprised four types of manufacturing industry such as two workplaces of products of wood, cork, straw and plaiting materials manufacturing industries, one casting metal manufacturing industry, and one parts and accessories for motor vehicles and it′s engines manufacturing industry. Workplaces contained in this study were located in some manufacturing area of Busan industrial complex and this study was carried out during a period from January 2003 to December 2004. Analytical accuracy, precision and detection limit of two methods was compared. Exposure level of its airborne concentration was evaluated in formaldehyde generating workplaces those were classified by types of industry, working process, and time. The results were as follows ; 1. A rate of recovery was 107.1% in impinger method and 101.8% in passive method, and precision was 7.79% in impinger method and 4.40% in passive method. There was no statistical significance in analytical accuracy and precision between two methods. A limitation of detection was 0.011 ppm in passive method which was lower than that of impinger method (0.020 ppm) by 1.8 times. 2. Airborne formaldehyde concentration of impinger method was different from passive method. It′s concentration by passive method was higher by 5.1 times than that by impinger method in the parts and accessories for motor vehicles and it′s engines manufacturing industry (P<0.05). Only in molding process among several types of processes, formaldehyde concentration in passive method was higher by 5.1 times than that in impinger method (P<0.05). Furthermore, formaldehyde concentration in passive method was higher by 1.7 times than that in impinger method (P<0.05) in the first half of year 2003. 3. The geometric mean of formaldehyde concentration in impinger method was lower than that in passive method, but there was no statistical significance of formaldehyde concentration by the difference of sampling method. In conclusion, it is difficult to conclude which is better between the two sampling methods because of no statistical significance for the difference of concentration. Because of lacks of certified passive sampling and analytical method, at present situation, studies on verification of accuracy and precision, obstructive reaction against validity on its exposure assessment, and research to develop domestically manufactured passive sampler in terms of cost-effectiveness should be continuously carried out.

Investigation of Risk Acceptance and Expectations in Facial Allotransplantation (안면 동종이식에 대한 위험 승인도와 기대치 조사)

  • Park, Sang-Ryul;Kim, Ji-Hoon;Hwang, Jae-Ha;Kim, Kwang-Seog;Lee, Sam-Yong
    • Archives of Plastic Surgery
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    • v.37 no.5
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    • pp.555-560
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    • 2010
  • Purpose: Facial allotransplantation (FA) could provide an excellent alternative to current treatments for facial disfigurement. However, despite being technically feasible, there continues to be various ethical and psychosocial issues associated with the risks and benefits of performing FA. The purpose of this study is to investigate risk acceptance and expectations in FA. Methods: In a quantitative assessment of risk versus benefit with respect to FA, from 2004 to 2008, Barker et al. developed and published a questionnaire-based instrument (Louisville Instrument for Transplantation [LIFT]), which contained 237 standardized questions. In the current study, the authors assessed risk versus benefits and expectations of FA using a Korean version of the LIFT. Respondents in three study groups (lay public, n=140; medical students, n=120; doctors, n=34) were questioned about risk acceptance as related to immunosuppression and tissue rejection, and expectations as related to quality of life improvement, and functional and aesthetic outcomes. A summary of the data has been provided and statistical analyses were performed. Results: Among the three study groups, results indicated that doctors accept the least amount of risk for a facial allotransplant, followed by medical students, and finally lay public. There was a significant statistical difference in three of the four questions regarding risk acceptance between the groups (p < 0.05). In general, lay public exhibited higher expectations for facial allotransplantation than the other groups. Additionally, there was a significant statistical difference in the importance of aesthetic outcome between the groups (p < 0.05). Conclusion: The authors' data indicate the three populations have vastly different levels of risk acceptance and expectations with regard to FA. Therefore, it is very important that surgeons establish clear, open, and thorough communication with patients in their consultations regarding FA. This is particularly important with respect to whether or not a patient's level of risk acceptance and expectations are progmatic.