• Title/Summary/Keyword: statistical assessment

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Bone density around the fixture after function of implant molar prosthesis using CBCT (임플란트 보철 기능후 고정체 주변 콘빔CT 골밀도 평가)

  • Jung, Jae-Hyun;Hwang, In-Taik;Jung, Byung-Hyun;Kim, Jae-Duk;Kang, Dong-Wan
    • Imaging Science in Dentistry
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    • v.40 no.1
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    • pp.1-7
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    • 2010
  • Purpose : The purpose of this study was to examine the significance of increased bone density according to whether bone grafts were applied using demographic data with Cone Beam Computed Tomography (CBCT) and to compare the bone densities between before and after implant prosthesis using the Hounsfield index. Materials and Methods : Thirty-six randomly selected computed tomography (CT) scans were used for the analysis. The same sites were evaluated digitally using the Hounsfield scale with V-Implant $2.0^{TM}$, and the results were compared with maxillary posterior bone graft. Statistical data analysis was carried out to determine the correlation between the recorded Hounsfield unit (HU) of the bone graft and implant prosthesis using a Mann-Whitney U test and Wilcoxon Matched-pairs test. Results : The bone grafted maxillary posterior teeth showed an increase in the mean values from-157 HU to 387 HU, whereas non-grafted maxillary posterior teeth showed an increase from 62 HU to 342 HU. After implantation, the grafted and non-grafted groups showed significantly higher bone density than before implantation. However, the grafted group showed significantly more changes than the non-grafted group. Conclusion : Bone density measurements using CBCT might provide an objective assessment of the bone quality as well as the correlation between bone density (Hounsfield scale) and bone grafts in the maxillary molar area.

Electromagnetic Field Exposure and Male Breast Cancer Risk: A Meta-analysis of 18 Studies

  • Sun, Jing-Wen;Li, Xiao-Rong;Gao, Hong-Yu;Yin, Jie-Yun;Qin, Qin;Nie, Shao-Fa;Wei, Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.523-528
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    • 2013
  • Background: The possibility that electromagnetic fields (EMF) exposure may increase male breast cancer risk has been discussed for a long time. However, arguments have been presented that studies limited by poor quality could have led to statistically significant results by chance or bias. Moreover, data fo the last 10 years have not been systematically summarized. Methods and Results: To confirm any possible association, a meta-analysis was performed by a systematic search strategy. Totals of 7 case-control and 11 cohort studies was identified and pooled ORs with 95% CIs were used as the principal outcome measures. Data from these studies were extracted with a standard meta-analysis procedure and grouped in relation to study design, cut-off point, exposure assessment method, adjustment and exposure model. A statistical significant increased risk of male breast cancer with EMF exposure was defined (pooled ORs = 1.32, 95% CI = 1.14-1.52, P < 0.001), and subgroup analyses also showed similar results. Conclusions: This meta-analysis suggests that EMF exposure may be associated with the increase risk of male breast cancer despite the arguments raised.

Diabetes Mellitus Reduces Prostate Cancer Risk - No Function of Age at Diagnosis or Duration of Disease

  • Xu, Hua;Mao, Shan-Hua;Ding, Guan-Xiong;Ding, Qiang;Jiang, Hao-Wen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.441-447
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    • 2013
  • Background: Prior studies examining the relation between diabetes mellitus (DM) and prostate cancer risk have reported controversial findings. We examined this association by conducting a detailed meta-analysis of the peer-reviewed literature. Methods: A comprehensive search for articles of MEDLINE and EMBASE databases and bibliographies of retrieved articles published up to November, 2012 was performed. Methodological quality assessment of the trials was based on the Newcastle-Ottawa Scaleq and the meta-analysis was performed using STATA 12.0. Dose-response regression was conducted with SPSS 19.0. Results: We included 29 studies in the meta-analysis (13 case-control studies, 16 cohort studies), and found an inverse association between DM and prostate cancer (relative risk (RR) 0.84, 95% confidence interval (CI), 0.78-0.91). An inverse association was also observed in non-Asian populations (RR 0.81, 95% CI 0.76-0.87) and population-based studies (RR 0.80, 95% CI 0.77-0.91). No statistical significance was found of the association between prostate cancer risk and the duration of DM (p=0.338), and risk seemed not related with the age of DM diagnosis. Conclusions: This study suggested an inverse relationship between DM and prostate cancer, but without links to duration of disease or age of diagnosis.

Comparison of Univariate and Multivariate Gene Set Analysis in Acute Lymphoblastic Leukemia

  • Soheila, Khodakarim;Hamid, AlaviMajd;Farid, Zayeri;Mostafa, Rezaei-Tavirani;Nasrin, Dehghan-Nayeri;Syyed-Mohammad, Tabatabaee;Vahide, Tajalli
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1629-1633
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    • 2013
  • Background: Gene set analysis (GSA) incorporates biological with statistical knowledge to identify gene sets which are differentially expressed that between two or more phenotypes. Materials and Methods: In this paper gene sets differentially expressed between acute lymphoblastic leukaemia (ALL) with BCR-ABL and those with no observed cytogenetic abnormalities were determined by GSA methods. The BCR-ABL is an abnormal gene found in some people with ALL. Results: The results of two GSAs showed that the Category test identified 30 gene sets differentially expressed between two phenotypes, while the Hotelling's $T^2$ could discover just 19 gene sets. On the other hand, assessment of common genes among significant gene sets showed that there were high agreement between the results of GSA and the findings of biologists. In addition, the performance of these methods was compared by simulated and ALL data. Conclusions: The results on simulated data indicated decrease in the type I error rate and increase the power in multivariate (Hotelling's $T^2$) test as increasing the correlation between gene pairs in contrast to the univariate (Category) test.

ZD1839 and Cisplatin Alone or in Combination for Treatment of a Nasopharyngeal Carcinoma Cell Line and Xenografts

  • Gu, Wei-Guang;Huang, Yan;Yuan, Zhong-Yu;Peng, Rou-Jun;Luo, Hai-Tao;He, Zhi-Ren;Wang, Shu-Sen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1787-1790
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    • 2013
  • This study evaluated the effects of ZD1839, an orally active, selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, on nasopharyngeal carcinoma (NPC) both in vitro and in vivo. Influence of ZD1839 alone or combined with cisplatin on the NPC cell line CNE2 was detected by MTT assay with flow cytometry assessment of cell cycle distribution and apoptosis rates. Nude mice NPC xenografts were also used to evaluate the effects of ZD1839 alone or combined with cisplatin. The Student's t test evaluated statistical significance. ZD1839 alone or combined with cisplatin inhibited CNE2 cell line proliferation. ZD1839 induced CNE2 cell cycle arrest in the G1 phase, and higher concentrations induced apoptosis. Xenograft tumors were significantly smaller when treated with 200 mg/kg ZD1839, cisplatin, or cisplatin combined with 100 mg/kg ZD1839 than untreated controls. ZD1839 (200 mg/kg) alone showed good tumor inhibition effects, reduction of tumor weights, and smaller tumor volume without loss of body weight. ZD1839 (200 mg/kg) might provide a good and effective therapeutic reagent for NPC.

Effect of Changing positions on aged circulation (체위 변화가 노인들의 순환에 미치는 영향에 관한 연구)

  • Hong K.P.;Lee S.H.;Eun Y.;Kang H.Y.
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.2 no.2
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    • pp.239-251
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    • 1995
  • The prevalence of postural hypotension among over 65 year old men is 10-30%. The postural hypotension commonly causes the discomfort such as dizziness, irritability or fainting spell, and for the result it diminishes the quality of the life of aged. Therefore the assessment and intervention of postural hypotension during changing position is very important. The purpose of this study is to investigate the effect of changing position from supine to standing upright, from supine through left lateral to standing upright, from supine through sitting to standing upright of aged. The results obtained are as follows : 1. The average systolic blood pressure of normotension group is $132.68{\pm}16.04mmHg$ at supine position. The average diastolic blood pressure of normotension group is $80.72{\pm}9.82mmHg$ at supine position. The average systolic blood pressure of hypertension group is $153.92{\pm}20.12mmHg$ at supine position. The average diastolic blood pressure of hypertension group is $93.74{\pm}15.53mmHg$ at supine position. 2. There is no significant difference of blood pressure after three different procedures as mentioned above from supine to standing upright. 3. The prevalence of postural hypotension at standing upright is 13.5% which is 18.8% of the hypertension group and 9.4% of the normotension group. There is statistical difference of the prevalence of postural hypotension between hypertension group and normotension group.

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A Study on Brand Personality Factors as Recognized by the Customers of Contract Foodservice Management Companies (위탁급식업체 고객들이 인식하는 브랜드 개성 요인 연구)

  • Kim, Ok-Seon;Jeon, Hui-Jeong
    • Journal of the Korean Dietetic Association
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    • v.13 no.1
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    • pp.38-49
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    • 2007
  • The purpose of this study was to determine the attributes and factors of brand personality for contract foodservice management companies. Self-administered questionnaires were distributed to five students at universities operating under the top five companies in contract foodservice management. The following statistical analyses were conducted for the data assessment: descriptive analysis, t-test, ANOVA, reliability analysis, and factor analysis, using the SPSS Win(12.0) package program. From these analyses we divided a company's brand personality into the following five functional and emotional elements: sensibility, sincerity, confidence, competence, and excitement. Based on these five elements a total of 26 scales were developed to measure brand attributes of the companies. The variance was explained by 19.29% of sensibility, 17.65% of sincerity, 15.71% of confidence, 14.06% of competence, and 13.62% of excitement. The calculated Cronbach's alpha was more than .90 for all the scales measuring the five attributes, indicating good internal consistency. There were significant differences in sensibility(p<.01), sincerity(p<.001), creditability(p<.01), competence (p<.001), and excitement(p<.001) among the companies. In regards to overall brand personality, company a had a higher mean score for sincerity, while the other companies had higher mean scores for competence. Among the brand personalities, 'confidence' had the highest mean score with 3.36, followed by 'cooperation' (3.17), 'successful'(3.12), 'leadership'(3.11), and 'down-to-earth'(3.02).

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Overview of Seismic Loads and Application of Local Code Provisions for Tall Buildings in Baku, Azerbaijan

  • Choi, Hi Sun;Sze, James;Ihtiyar, Onur;Joseph, Leonard
    • International Journal of High-Rise Buildings
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    • v.3 no.1
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    • pp.65-71
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    • 2014
  • Baku, the capital of Azerbaijan, has seen a boom in construction in recent years. The old Baku city has been rapidly transforming into a new hub of high-rise buildings and lively cultural centers hosting the Euro Vision Song Contest in 2012 and European Games in 2015. A major population shift to Baku from its suburbs and the countryside has resulted in the doubling of Baku's population in the 4 years between 2009 and 2013. As of January 2013, Baku's population reached four million people, 43% of the citizens in Azerbaijan according to The State Statistical Committee of Azerbaijan. With this trend, the city needs more high-rise buildings to accommodate rapidly increasing demands for more housing and business space. Until the Azerbaijan Seismic Building Code was published in 2010 and became effective, many different seismic criteria, in terms of building codes and seismic intensities, were used for all new high-rise projects in Baku. Some designers used the SNIP (Russian) code with seismic level 9 or level 8 with 1 point penalty. Others used the Turkish code with Seismic Zone 1, UBC 97 with Zone 2 through 4, or IBC with Sa = 0.75 g through 1.0 g. The seismic intensity is now clarified with the Azerbaijan Seismic Building Code. However, the Azerbaijan Seismic Building Code is appropriate for low-rise buildings applications but may be inappropriate for high-rise project applications. This is because the code-defined response spectrum yields unrealistically conservative seismic forces for high-rise buildings with long periods, as compared to those determined by other internationally accepted building codes. This paper provides observations and recommendations for code-based seismic load assessment of high-rise buildings in the Baku area.

Assessment of Shear Band Characteristics in Granular Soils Using Digital Image Analysis Technique for Plane Strain Tests (평면변형률 시험에서 이미지 해석을 통한 사질토의 전단면 특성 평가)

  • Jang, Eui-Ryong;Jung, Young-Hoon;Kim, Jun-Young;Chung, Choong-Ki
    • Journal of the Korean Geotechnical Society
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    • v.27 no.4
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    • pp.51-65
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    • 2011
  • Shear banding, the localization of deformation into thin zones, has a quite practical relevance, as stability and deformation characteristics of earth structures are controlled by the soil behavior within the shear band. In this study, for understanding occurrence and developed pattern of shear band, plane strain compression tests were performed on three soils with different particle-size distribution under various conditions. Digital images were captured during the experiments; then, deformation of a specimen was evaluated by digital image analysis technique. The characteristics of a shear band were evaluated from the state shortly after post-peak occurrence to critical state. Additionally, the statistical procedure was developed to determine the reasonable thickness of a shear band.

Comparison of Radiologic Parameters between Weight Bearing Affected Single Ankle Anteroposterior View and both Ankle Anteroposterior View in Ankle Osteoarthritis (족관절 관절염이 있는 환자에서 체중 부하상태의 양측 족관절과 환측 족관절 전후면 방사선 사진의 방사선학적 측정치의 비교)

  • Kim, Jung-Rae;Lee, Woo-Chun
    • Journal of Korean Foot and Ankle Society
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    • v.15 no.3
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    • pp.159-164
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    • 2011
  • Purpose: This study was performed to analyze the results of radiologic parameters between weight bearing affected single ankle anteroposterior (AP) view and both ankle AP view in ankle osteoarthritis (OA). Materials and Methods: Between January 2009 and August 2010, 41 patients (50 ankles) who visited our institution to treat ankle OA were reviewed retrospectively. In radiographic assessment, weight bearing affected single ankle AP view and both ankle AP view were checked, and measured tibial anterior surface angle (TAS), tibial medial malleolar angle (TMM), talar tilting angle (TT), maximum and minimun joint space width (JSW) of ankle, width between articular surface of medial malleolar and medial articular surface of talus as radiologic parameters. Results: On weight bearing both ankle AP view, TAS was $85.4{\pm}4.1^{\circ}$, TMM was $33.1{\pm}9^{\circ}$, TT was $5.4{\pm}6.1^{\circ}$, maximum JSW was $3.2{\pm}2.7$ mm, minimum JSW was $1.1{\pm}1.3$ mm, width between articular surface of medial malleolar and medial articular surface of talus was $1.8{\pm}1.8$ mm and on weight bearing affected ankle AP view, TAS was $85.3{\pm}3.9^{\circ}$, TMM was $34.3{\pm}10.9^{\circ}$, TT was $5.4{\pm}6.5^{\circ}$, maximum JSW was $3.2{\pm}2.7$ mm, minimum JSW was $1.1{\pm}1.3$ mm, width between articular surface of medial malleolar and medial articular surface of talus was $1.6{\pm}1.7$ mm. Conclusion: There is no statistical significance in radiologic parameters between weight-bearing affected single ankle AP view and both ankle AP view in ankle OA.