• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.81.1-81.1
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• 2015

FIMS/SPEAR is a dual-channel far-ultraviolet imaging spectrograph on board the Korean microsatellite STSAT-1, which was launched on 2003 September 27. While the instrument is optimized for the observation of diffuse emissions, it was able to observe a number of bright stars without much contamination from the diffuse background or other faint stars. In this paper, we present a catalog of the far-ultraviolet spectra for 543 stars observed by FIMS/SPEAR during its mission lifetime of a year and a half, covering over the 80% of the sky. Of these, 296 stars were also observed by the International Ultraviolet Explorer (IUE), which covered a wide spectral band including the FIMS wavelength band (1370--1710 A). The stellar spectral types involved in the catalog span from B0 to A3. We compare the new spectra with those of IUE when they are available, and discuss some examples. We also revised the effective area of FIMS that the FIMS stellar spectra are consistent with the IUE spectra.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.77.2-77.2
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• 2016

We present preliminary results of the analysis of chemical abundances for seven hypervelocity star (HVS) candidates. These objects are G and K dwarfs in the Galactic disk selected from the Sloan Extension for Galactic Understanding and Exploration. Unlike other HVSs discovered thus far, their stellar orbits and kinematics suggest that they do not originate in the Galactic center or in an accretion event. These factors imply yet-unknown mechanisms that give rise to these kinematically-extreme disk stars. In order to study in detail their progenitors and possible formation mechanisms, we obtained spectra of these stars at a resolving power of R~6000, with the Dual Imaging Spectrograph at the Apache Point Observatory. We derive the abundances of chemical elements, C, Mg, Ca, Ti, Cr, Fe, and Ba from the observed spectra, using MOOG. We compare them with the ones of typical Galactic disk stars and discuss discrepancies between them to search for clues to their origin.

• Journal of Ocean Engineering and Technology
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• v.37 no.6
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• pp.225-237
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• 2023

In this study, numerical simulations for a single fixed truncated circular cylinder in regular waves were conducted to investigate the nonlinear wave run-up under various dampers and wave period conditions. The present study used the volume of fluid (VOF) technique to capture the air-water interface. The unsteady Reynolds-averaged Navier-Stokes (URANS) equation with the k- 𝜖 turbulence model was solved using the commercial computational fluid dynamics (CFD) software STAR-CCM+. First, a systematic spatial convergence study was conducted to assess the performance and precision of the present numerical wave tank. The numerical scheme was validated by comparing the numerical results of wave run-up on a bare truncated cylinder with the experimental results, and a good agreement was achieved. Then, a series of parametric studies were carried out to examine the wave run-up time series around the truncated cylinder with single and dual dampers in terms of the first- and second-order harmonic and mean set-up components. Additionally, the local wave field and the flow velocity vectors adjacent to the cylinder were evaluated. It was confirmed that under short wave conditions, the high position of the damper led to a noticeable increase in the wave run-ups with significant changes in the first- and second-order harmonic components.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.25 no.4
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• pp.434-439
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• 2023

Pseudoaneurysms are rare but devastating complications of penetrating head traumas. They require rapid surgical or endovascular intervention due to their high risk of rupture; however, complex presentations may limit treatment options. Our objective is to report a case of severe vasospasm, flow diversion, and in-stent stenosis complicating the treatment of a middle cerebral artery pseudoaneurysm following a gunshot wound. A 33-year-old woman presented with multiple calvarial and bullet fragments within the right frontotemporal lobes and a large right frontotemporal intraparenchymal hemorrhage with significant cerebral edema. She underwent an emergent right hemicraniectomy for decompression, removal of bullet fragments, and evacuation of hemorrhage. Once stable enough for diagnostic cerebral angiography, she was found to have an M1 pseudoaneurysm with severe vasospasm that precluded endovascular treatment until the vasospasm resolved. The pseudoaneurysm was treated with flow diversion and in-stent stenosis was found at 4-month follow-up angiography that resolved by 8 months post-embolization. We report the successful flow diversion of an middle cerebral artery (MCA) pseudoaneurysm complicated by severe vasospasm and later in-stent stenosis. The presence of asymptomatic stenosis is believed to be reversible intimal hyperplasia and a normal aspect of endothelial healing. We suggest careful observation and dual-antiplatelet therapy as a justified approach.

• International Journal of Stem Cells
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• v.15 no.4
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• pp.359-371
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• 2022

Background and Objectives: The goal of this study was to investigate the mechanism of mesenchymal stem cell (MSC)-derived microRNA (miR)-150-5p-expressing exosomes in promoting skin wound healing through activating PI3K/AKT pathway by PTEN. Methods and Results: Human umbilical cord (HUC)-MSCs were infected with miR-150-5p overexpression and its control lentivirus, and HUC-MSCs-derived exosomes (MSCs-Exos) with stable expression of miR-150-5p were obtained. HaCaT cells were induced by H₂O₂ to establish a cellular model of skin injury, in which the expression of miR-150-5p and PTEN and the phosphorylation of PI3K and AKT were evaluated. HaCaT cells were transfected with pcDNA3.1-PTEN or pcDNA3.1 and then cultured with normal exosomes or exosomes stably expressing miR-150-5p. Cell proliferation was inspected by CCK-8. Cell migration was detected by scratch test and cell apoptosis by flow cytometry. The starBase tool was used to predict the binding site of miR-150-5p to PTEN. Dual-luciferase reporter assay and RIP assay were applied to assess the interaction between miR-150-5p and PTEN. In H₂O₂-induced HaCaT cells, the miR-150-5p expression decreased, and PTEN expression increased in a concentration-dependent manner. MSCs-Exos promoted the growth and migration of H₂O₂-induced HaCaT cells and inhibited their apoptosis. In addition, overexpression of exosomal miR-150-5p enhanced the protective effect of MSCs-Exos on H₂O₂-induced HaCaT cells; PTEN overexpression in HaCaT cells partially restrained miR-150-5p-mediated inhibition on H₂O₂-induced injury in HaCaT cells. PTEN was a target gene of miR-150-5p. MiR-150-5p regulated PI3K/AKT pathway through PTEN. Conclusions: MSCs-derived miR-150-5p-expressing exosomes promote skin wound healing by activating PI3K/AKT pathway through PTEN.