• Natural Product Sciences
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• 제25권2호
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• pp.165-171
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• 2019

Although the functions of a standardized extract of Gingko biloba leaves (EGb $761^{(R)}$) has been reported with regard to neurobiological properties, no attention has been paid to the impact of EGb $761^{(R)}$ on the neuronal regulation of energy homeostasis. To evaluate the hypothesis that EGb $761^{(R)}$ affect the secretion of peptide tyrosine tyrosine (PYY) and the activation of free fatty acid receptor 4 (FFA4), which are involved in the neuronal circuitries that control energy homeostasis by inducing the transfer of information about the influx of energy to the brain, we examined whether EGb $761^{(R)}$ can stimulate PYY secretion in the enteroendocrine NCI-H716 cells and if EGb $761^{(R)}$ can activate FFA4 in FFA4-expressing cells. In NCI-H716 cells, EGb $761^{(R)}$ stimulated PYY secretion and the EGb $761^{(R)}$-induced PYY secretion was involved in the increase in intracellular $Ca^{2+}$ concentration and the activation of FFA4. Furthermore, in FFA4-expressing cells, EGb $761^{(R)}$ activated FFA4. These results suggest that EGb $761^{(R)}$ may affect the control of energy homeostasis via the regulation of PYY secretion and FFA4 activation.

• Design & Manufacturing
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• 제16권3호
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• pp.16-21
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• 2022

In order to reduce the weight of parts and materials for the development of high-efficiency engines in accordance with the strengthening of automobile fuel efficiency regulations, the existing casting material is changed to a iron plate material, and plastic processing and turning operations are performed to lighten the weight and reduce the manufacturing cost. Among the pulley components applied to the damper pulley, the HUB product was manufactured by plastic machining instead of the existing casting process, and the inspection standardized for automating the inner diameter and parallelism measurement of the turning result of the new hub part with improved quality, and the inspection system for this Development of design and operation software to automate the inspection of the inner diameter and parallelism of the hub was described. The representative specifications of the development equipment are a hub inner diameter 22mm inspection system, a three-point inspection system with a parallelism of 0.15mm on the top.

• 열처리공학회지
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• 제35권3호
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• pp.139-149
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• 2022

In the automobile and shipbuilding industries, various materials and components require superior surface strength, excellent wear resistance and good resistance to repeated loads. To improve the surface properties of the materials, various surface heat treatment methods are used, which include carburizing, nitriding, and so on. Among them, carburizing treatment is widely used for structural steels containing carbon. The effective carburizing thickness required for materials depends on the service environment and the size of the components. In general, however, there is a limit in evaluation of the surface properties with a standardized mechanical test method because the thickness or cross-sectional area of the carburized layer is limited. In this regard, the nanoindentation technique has lots of advantages, which can measure the mechanical properties of the material surface at the nano and micro scale. It is possible to understand the relationship between the microstructural change in the hardened layer by carburizing treatment and the mechanical properties. To be spread to practical applications at the industrial level, in this paper, the principle of the nanoindentation method is described with a representative application for analyzing the mechanical properties of the carburized material.

• Archives of Plastic Surgery
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• 제34권6호
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• pp.685-690
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• 2007

Purpose: Numerous materials, both autologous and nonautologous, have been used for augmentation of sunken areas and each has its own limitations. The ideal material for augmentation should not be absorbed in any manner. This study is designed to assess the survival of $SureDerm^{(R)}$, $Permacol^{(R)}$ graft according to the volume and histologic change. Methods: Twenty four mice, weighing about 50 grams and of 5 weeks of age were used. $SureDerm^{(R)}$ is an acellular dermal matix obtained from human cadeveric skin. $Permacol^{(R)}$ is a porcine derived acellular dermal matrix whose manufacture involves trypsinisation, solvent extraction. Graft pieces standardized to $1{\times}1cm$ size were used in each group. The implanted material were taken 1, 4, 8 and 12 weeks later, respectively. The changes of graft volume during the graft period were measured on initial, 1, 4, 8 and 12 weeks. Results: The initial shape of graft was maintained up to 12 weeks in $Permacol^{(R)}$ graft group and mean survival rate was $80.36{\pm}8.21%$ in $SureDerm^{(R)}$, $89.57{\pm}6.39%$ in $Permacol^{(R)}$(p=0.01). The volume of each graft decreased 29% from initial volume on 12 weeks in $SureDerm^{(R)}$, 18% in $Permacol^{(R)}$. The structure of $Permacol^{(R)}$ remained until 12 week after implantation. Conclusion: Our experimental study suggests that $Permacol^{(R)}$ could be a safe material as an implant for permanent augmentation. However, There are further study remained for antigenicity of these material, and the choice of graft for augmentation should be remained to the clinical situations.

• 한국정밀공학회지
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• 제31권4호
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• pp.303-309
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• 2014

This paper contains how to integrate production resources of 4M1E (Man, Machine, Material, Method and Energy), analyze and collect various type of management information which emphasize the need of a common platform's 4M1E Middleware and Autonomous Configuration. Management efficiency improved by the functionality of integrated management information and digitizing information with standardized data.

• Steel and Composite Structures
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• 제24권3호
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• pp.383-391
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• 2017

The goal of this study is to investigate structural analysis and behaviors of an innovative aerial work platform truss frame whose ductility is improved by using high strength-steel UL-700. The present space truss frame can move or stop through tunnels for maintenance constructions by automatic facilities and workmanship within standardized limited building lines of tunnel. Most of all, this method overcomes problematic, which is to block cars during construction periods, seriously, of typical methods like as using truck and scaffolds for tunnel maintenance. According to evaluated appropriate design results of space truss frames of numerical examples by using a commercial MIDAS GEN program, it is verified that design parameters such as layered size, cross-sectional size, and steel material of the present space truss frame are determined to depend on characteristics such as lanes or shape of road tunnels.

• 도시과학
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• 제7권1호
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• pp.5-9
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• 2018

The nickel-titanium shape memory alloy (SMA), referred to as Nitinol, exhibits a superelastic effect that can be restored to its original shape even if a significant amount of deformation is applied at room temperature, without any additional heat treatment after removal of the load. Owing to these unique material characteristics, it has widely used as displacement control devices for seismic retrofitting in civil engineering fields as well as medical, electrical, electronic and mechanical fields. Contrary to ordinarty carbon steel, superelastic SMAs are very resistant to fatigue, and have force-displacement properties depending on loading speed. The change for the mechanical properties of superelastic SMAs are experimentally inviestigated in this study when loading cycle numbers and loading speeds are different. In addition, the standardized force-displacement properties of such superelastic SMAs are proposed with an aim to efficiently design the seismic retrofitting devices made of these materials.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7761-7762
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• 2013

Alternative strategies such as visual inspection of cervix with acetic acid, are real time, economical and easily implemented methods for cervical cancer screening. However, variable sensitivity and specificity have been observed in various community based studies. The possible reasons could include variation in man power training, light source used for visualization, and preparation of diluted (4-5%) acetic acid and its storage. A standardized protocol for training, teaching material (easy to understand in the local language) for trainees, supervision and reinforcement by intermittent and supplementary training to check the quality of their observation, a standard protocol for preparation dilute acetic acid and its storage and a standard good light source (equivalent to day light) are needed to minimize the variation in sensitivity and specificity of VIA in community settings.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2006년도 춘계학술발표회 논문집(I)
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• pp.222-225
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• 2006

Pull-off test is widely used to evaluate bond performance between concrete and FRP composite. However, reliability of experiment result declines due to many difference between test methods of each national standards. This study analyzed problems of various existing test methods for pull-off test and suggested standardized test method. In addition, since tensile strength of concrete is smaller than bond strength of epoxy resin, maximum bond strength of epoxy resin shall be limited within tensile strength of concrete. Alternative testing method, therefore, which decrease FRP adhesion areas than concrete adhesion areas is suggested to widen test range of bond strength in pull-off test. In the experimental results, bond performance can be estimated up to two times of tensile strength of concrete by reducing FRP adhesion areas by 1/3.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 춘계학술대회 논문집
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• pp.193-198
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• 2005

According to the ISO 14040(1997), Life Cycle Assessment is not the tool only focusing on the emissions from the manufacturing processes of a product, but the tool also expressing environmental adverse impact quantitatively through products entire life cycle (i.e. raw material acquisition, manufacturing, transportation, use, and end-of-life stage). Because the LCA for EMUs(Electrical Multiple Units), however, requires astronomical time and cost for collecting big amount of data. it is inevitable to bring in the simplified LCA methodology, In this study, we introduced standardized methodology of LCA in the world, and found appropriate S-LCA methodology for EMUs. Furthermore, we recommended how to evaluate the environmental impact of EMUs in detail and precisely, using the S-LCA.