• Korean Journal of Pharmacognosy
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• v.44 no.4
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• pp.397-401
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• 2013

The Galkun-Whanglyeon-Whanggum-Tang, an officially standardized mixture of traditional herbal medicines used in Korea and China, consists of Pueraria lobata, Scullellaria baicalensis, Coptis chinensis and Glycyrrhiza uralensis at a ratio of 6:9:3:2.4. In this study, we evaluated the effect of lowering lipid accumulation in blood by treatment of Galkun-Whanglyeon-Whanggum-Tang in Apo E(-/-) atherosclerotic animal model. ApoE/mice fed with 1.25% cholesterol, 7.5% cocoa butter and 0.5% sodium cholate diet were orally given vehicle or Galkun-Whanglyeon-Whanggum-Tang(10, 100 and 300 mg/kg/day) for 12 weeks. Serum levels of triglyceride(TG), total cholestrerol(TC), low-density lipoprotein(LDL) and high-density lipoprotein(HDL) were analyzed, and PPAR-${\alpha}$ and PPAR-${\gamma}$ were examined by Western blotting analysis. Galkun-Whanglyeon- Whanggum-Tang decreased serum levels of TG, TC and LDL, but not HDL in ApoE/mice. In parallel, Galkun-Whanglyeon-Whanggum-Tang treatment showed the increased activity of PPAR-${\alpha}$ and PPAR-${\gamma}$ in hepatocytes. In summary, Galkun-Whanglyeon-Whanggum-Tang can reduce lipid accumulation in blood, and this effect might be accompanied by the upregulation of PPAR-${\alpha}$ and PPAR-${\gamma}$ in Apo E(-/-) atherosclerotic mouse model.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.5
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• pp.913-920
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• 2011

Distribution systems for operating the various systems should be operated organically. Distribution systems for organic operations extend the functionality of the system and system integration for the extension is doing. However, in systems integration for each unique non-standard definition of linkage and exchange systems are used. Non-standard definition of a unique linkage and exchange systems in the maintenance and expansion will result in many negative results. To solve these problems, the system and the exchange of information about the links between systems should define standards. IEC (International Electrotechnical Commission) power to solve these problems in the field of the Common Information Model (Common Information Model, CIM) standard (IEC61970, IEC61968) is defined as the transmission and distribution system integration and standardization for the exchange of information. In this paper, standardized system for building CIM-based distribution automation system should describe the process of building. In addition, the process of establishing a common information model needed (CIM) defined and associated services for a defined set of models is proposed in the standardization process.

• Korean Journal of Veterinary Research
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• v.43 no.4
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• pp.697-702
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• 2003

The purpose of this study was to investigate the effects of a protein-free, standardized dialysate/ultrafiltrate (HD) derivatives from calf blood (Solcoseryl$^{(R)}$) for second-intention full-thickness skin wound healing in dogs. Three $2{\times}2cm$ area-matched full-thickness skin wounds were created bilaterally on the dorsolateral aspect of the trunk of nine dogs. In each dog, two wounds were treated with HD, cemella asiatica extract (Centrasol$^{(R)}$) and normal saline, respectively. For six weeks, the wounds were evaluated grossly for contraction, epithelialization and healing and were examined histopathologically. In the first week of the wound healing period, HD stimulated wound contraction and healing more significantly than centasol and normal saline (p<0.05). Neutrophils were more increased in the HD-treated wounds than those in centasol or normal saline treated wounds. In the second week, HD stimulated epithelialization more significantly than centasol or normal saline (p<0.05), and neovascularization and granulation more increased in the HD-treated wounds than those in centasol and normal saline treated wounds. In conclusion, HD was the most effective on early wound contraction, epithelialization and healings among three experimental drugs in full-thickness skin wound.

• Journal of Korean Physical Therapy Science
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• v.27 no.2
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• pp.36-47
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• 2020

Background: This study purposed to provide meaningful information for the accumulation of knowledge on coordinative locomotor training in patients with stroke. Design: Meta-analysis. Methods: This study collected articles which the coordinative locomotor training in patients with stroke. For systematic meta-analysis, 6 articles were finally selected after searching based on the PICOSD criteria. This meta-analysis was conducted according to PRISMA guidelines. Randomized controlled trials were included and the risk of bias was evaluated for each study. Pooled standardized mean differences were calculated using a random effects model. To extract the effect size of each study, the R 3.5.3 software was used. Results: The meta-analysis showed that a total effects size was 1.23 indicating that coordinative locomotor training for patients with stroke had a maximum effect size. Conclusion: A meta-analysis is warranted for further research to determine the effects of coordinative locomotor training in patients with stroke on muscle strength, walking and range of motion.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.4
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• pp.1114-1132
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• 2016

The objective of present study is to compare the similarities and differences between the two projects and extract implications for the improvement of higher education quality in other countries. To meet this objective, The study compared and analyzed "The Project of Higher Education Quality Development and Educational Reform of China" and "Technical Education Quality Improvement Programme" of government of India. by using the method of literature research, contents analysis and comparison analysis, this paper employed multi-source materials to examine background and targets, measures and outcomes, deficiencies and future direction of these two projects, and compared the similarities and diversities on each matters by utilizing secondary data from national surveys, government statistics, databases, and third-party agencies. The findings led us to suggest that the well-coordinated and standardized administrative system is a primary guarantee for ensuring the smooth implementation of the programme, and sharing educational resources among higher education institutions is an effective means for promoting their joint development. The improvement of higher education quality relies on the reform of the entire higher education system and the efficient networking between higher education institutions.

• Journal of Environmental Science International
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• v.23 no.10
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• pp.1693-1701
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• 2014

A rapid and simple method for the quantitative determination of volatile fatty acids (VFAs; propionic acid, n-butyric acid, i-valeric acid and n-valeric acid) and indoles (phenol, p-cresol, 4-ethyl phenol, indole and skatole) in pig slurry and dog excrement using solid-phase micro-extraction (SPME) coupled to gas chromatography was evaluated. $50/30{\mu}m$ DVB/CAR/PDMS (Divinylbenzene/Carboxen/Polydimethylsiloxane) fiber was used to extract the target compounds in aqueous media. Sample amount and adsorption time was standardized for the routine analysis. Detection limits were from 0.11 to $0.15{\mu}gL$ for VFAs and from 0.12 to $0.28{\mu}gL$ for indoles and the correlations observed ($R^2$) were 0.975~1.000. This method was applied to the pig slurry, fertilizer, compost and dog excrement. In nearly all cases, the indoles were detected in concentrations of higher than their limits of detection (DOLs). But the VFAs in swine manure were below their DOLs.

• Korean Journal of Social Welfare
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• v.49
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• pp.95-128
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• 2002

The present study is designed to trace the successful reform steps taken within the vocational training system in the UK and to extract a set of instructive implications for Korea's future reform path towards an efficient vocational training system conducive to youth employment. To this end, this study focuses on three major aspects of the youth vocational training system: the government's role and partnerships between training and industry, the vocational training system, and the employment support system. Implications drawn from the comparative analysis are as follows. Vocational training reform should be made within the broad paradigm of youth employment promotion. All aspects of the youth vocational training system, such as the training program structure, program content, provider, management, so on, should be reformed, step by step, within a long-term plan. In addition to the vocational training reforms. employment support programs should be enlarged, and the service delivery system should be well structured in order to enhance the effects of the training reforms. For these reforms, it is essential to make fundamental changes in the following areas: integration of youth employment policy making and its administrative structures, reinforcement of partnerships between training and industry, nation-wide standardization of job skins, and the introduction of standardized job certificate classification on a national level.

• Genomics & Informatics
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• v.9 no.1
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• pp.19-27
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• 2011

Gene Expression Omnibus (GEO) has kept the largest amount of gene-expression microarray data that have grown exponentially. Microarray data in GEO have been generated in many different formats and often lack standardized annotation and documentation. It is hard to know if preprocessing has been applied to a dataset or not and in what way. Standard-based integration of heterogeneous data formats and metadata is necessary for comprehensive data query, analysis and mining. We attempted to integrate the heterogeneous microarray data in GEO based on Minimum Information About a Microarray Experiment (MIAME) standard. We unified the data fields of GEO Data table and mapped the attributes of GEO metadata into MIAME elements. We also discriminated non-preprocessed raw datasets from others and processed ones by using a two-step classification method. Most of the procedures were developed as semi-automated algorithms with some degree of text mining techniques. We localized 2,967 Platforms, 4,867 Series and 103,590 Samples with covering 279 organisms, integrated them into a standard-based relational schema and developed a comprehensive query interface to extract. Our tool, GEOQuest is available at http://www.snubi.org/software/GEOQuest/.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.5
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• pp.251-255
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• 2019

On today, Protocol reverse-engineering technique can be used to extract the specification of an unknown protocol. However, there is no standardized method, and in most cases, the extracting process is executed manually or semi-automatically. If the information about the structure of an unknown protocol could be acquired in advance, it would be easy to conduct reverse engineering. the feature extraction is an important step in unknown protocol classification. However, in this paper, we present a comparison several feature extraction techniques and suggests a method of feature extraction algorithm for recognizing unknown protocol. In order to verify the performance of the proposed system, we performed the training using eight open protocols to evaluate the performance using unknown data.

• Natural Product Sciences
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• v.27 no.1
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• pp.1-9
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• 2021

Methicillin-resistant Staphylococcus aureus (MRSA) infection often complicates burn wounds. Mupirocin is the antibiotic of choice for superficial MRSA infection, and its resistance is on the rise due to its frequent and widespread use. This study aimed to develop and evaluate Curcuma xanthorriza extract (CXE)-containing gel as a topical agent against MRSA-infected second-degree burn wound in rats. CXE was obtained using maceration with 96% ethanol. Xanthorrhizol level, antibacterial, and antioxidant activity were evaluated using a standardized method. In vivo, the wound's healing and bacterial load were evaluated every three days, whereas the histopathology of the wound was examined on day 12 of treatment. One-Way ANOVA and Kruskal-Wallis test were used to analyze the data. In this study, 27.0% and 7.10% of the obtained CXE were xanthorrhizol and curcumin, respectively. Additionally, an IC50 of 64.27 ppm was shown in antioxidant activity measurement, and MIC against MRSA was 5 mg/ml. Treatment with CXE-containing gels showed a significant reduction in bacterial load and proliferation of connective tissue in a dose-dependent manner. In conclusion, CXE-containing gel showed a greater reduction of bacterial load and more advanced wound healing phase than mupirocin.