• Title/Summary/Keyword: standard human model

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An Analysis of Panel Data on the Web-accessibility Policies of Local Governments in Korea (우리나라 웹 접근성 정책 영향요인 분석 - 16개 광역자치단체 패널데이터를 중심으로 -)

  • JIN, Sangki;HYUN, Joonho
    • Informatization Policy
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    • v.18 no.4
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    • pp.42-58
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    • 2011
  • This paper starts from one question: what are the key factors of the web accessibility policy, which is significant for realizing equity in the web and enhancing human dignity in the information society. To find significant factors for complying with web accessibility, this paper analyzes panel data of 16 Korean local governments (for five years: 2004-2009) according to the research design which is based on the demand and supply balance model and consists of four variables : 'legal and institutional environment (including legal infrastructure)', 'financial foundation (fiscal self-reliance ratio)', 'policy inputs (amount of imformatization budget, employee of information experts)'and 'policy demand (internet usage rate, the number of disabled people and elderly people)'. From the results of this study, this paper can explain the mechanism and impact factors on the web accessibility policy of Korean local governments. Some factors are critical to improve web accessibility: (1) the importance of policy demand, (2) the importance of policy inputs, (3) the importance of legal and institutional environment. Finally, this paper concludes with some suggestions to enhance the web accessibility capacity for Korean local governments: (1) improve awareness on web accessibility, (2) develop a standard and invest R&D on web accessibility, (3) foster experts in web accessibility.

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Osteogenic effects of polyethyleneimine-condensed BMP-2 genes in vitro and in vivo (Polyethyleneimine-응축 BMP-2 발현 유전자를 이용한 골형성 효과)

  • Cheong, Hee-Sun;Kim, Kyoung-Hwa;Park, Yoon-Jeong;Kim, Tae-Il;Lee, Yong-Moo;Ku, Young;Rhyu, In-Chul;Lee, Dong-Soo;Lee, Seung-Jin;Chung, Chong-Pyoung;Han, Soo-Boo;Seol, Yang-Jo
    • Journal of Periodontal and Implant Science
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    • v.37 no.4
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    • pp.859-869
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    • 2007
  • Naked DNA and standard vectors have been previously used for gene delivery. Among these, PEI can efficiently condense DNA and has high intrinsic endosomal activities. The aim of this study is to investigate whether the cationic polycation PEI could increase the transfection efficiency of BMP expressing DNA using a vector-loaded collagen sponge model. BMP-2/pcDNA3.1 plasmid was constructed by subcloning human BMP-2 cDNA into the pcDNA3.1 plasmid vector. PEI/DNA complexes were prepared by mixing PEI and BMP-2/pcDNA3.1 and the constructed complexes were loaded into the collagen sponges. In vitro studies, BMSCs were transfected with the PEI/BMP-2/pcDNA3.1 complexes from collgen sponge. The level of secreted BMP-2 and alkaline phosphatase activities of transfected BMSCs were significantly higher in PEI/BMP-2/pcDNA3.1 group than in BMP-2/pcDNA3.1 group (p<0.05). Transfected BMSCs were cultured and mineralization was observed only in cells treated with PEI/BMP-2/pcDNA3.1 complexes. In vivo studies, PEI/BMP-2/pcDNA3.1/collagen, BMP-2/pcDNA3.1/collagen and blank collagen were grafted in skeletal muscle of nude mice. Ectopic bone formation was shown in PEI/BMP-2/pcDNA3.1/collagen grafted mouse 4 weeks postimplantation, while not in BMP-2/pcDNA3.1 grafted tissue. This study suggests that PEI-condensed DNA encoding for BMP-2 is capable of inducing bone formation in ectopic site and might increase the transfection rate of BMP-2/pcDNA3.1. As a non-viral vector, PEI offers the potential in gene therapy for bone engineering.

A Study on Protection Depending on Mesh Size of Expanded Metal for Slope Reinforcement (사면보강용 Expanded Metal 격자크기에 따른 인발 특성 연구)

  • Ji, Younghwan;Kim, Kihwan;Kim, Sungho;Hwang, Yeongcheol;Lee, Seungho
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.12
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    • pp.47-56
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    • 2010
  • The construction of new roads and the consistent extension of already-existing roads or the line-shape revision of those roads are increased with the governmental investment to SOC facilities currently. Accordingly, the road cut slopes are in the trend of rapidly increasing. As the road slope has increased, a lot of human and property damages has entailed consequently and in the local case, numerous studies have carried out aiming at minimizing this damages caused by the rockfall and landslide. In general, standard falling rock prevention facility has employed for most of the local road slope based on "Guide for Installation and Management of Road Safety Facilities" published by MLTM(the Ministry of Land, Transport, and Maritime Affairs) but profound doubt has raised as to whether this rockfall prevention facility would function properly enough to prevent rockfall efficiently without any damages in case of actual occurrence of rockfall. In addition, it is a reality that in most cases, such work is relied on overseas technology as a whole as the local technical level is low and in case of rockfall prevention net, it is judged that a study on rockfall prevention net that is able to endure more powerful rockfall energy is required as the problem including net bursting is taken place as a result of enough bearing force being failed to be demonstrated due to its partial weak point(not uniformly made). Under this background, in this study, three kinds of model depending on mesh size of expanded metal that is considered to have an adoptability as rockfall prevention net, as target are selected and characteristics depending on mesh size of expanded metal is intended to be researched through a pull-out test performance by using pull-out test equipment rockfall prevention net.

Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists (CRF1 길항제 스크리닝을 위한 에쿼린 기반 세포실험 개발연구)

  • Noh, Hyojin;Lee, Sunghou
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.11
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    • pp.7575-7581
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    • 2015
  • Corticotropin-releasing factor(CRF), one of the stress driven neuropeptides, was widely proposed to influence hair loss and re-growth. For the development of receptor antagonists, the screening system based on intracellular calcium signal process was developed and optimized. The aequorin parental cells were transfected with CRF1 receptor and alpha 16 promiscuous G protein cDNA to establish HEK293a16/hCRF1, a stable cell line for the human CRF1 receptor. In HEK293a16/hCRF1 cells, the range of sauvagine dose response was 12-fold higher($EC_{50}:15.21{\pm}1.83nM$) than in the transiently expressed cells, hence essential conditions for the antagonist screening experiments such as the robust signals and high solvent tolerance were secured. The standard antagonists for the CRF1 receptor, antalarmin and CP154526, resulted $IC_{50}$ values of $414.1{\pm}5.5$ and $290.7{\pm}1.9nM$, respectively. Similar results were presented with frozen HEK293a16/hCRF1 cells. Finally, our HEK293a16/hCRF1 cells with the aequorin based cellular functional assay can be a model system for the development of functional cosmetics and modulators that can have a clinical efficacy on hair re-growth.

Optimum conditions for artificial neural networks to simulate indicator bacteria concentrations for river system (하천의 지표 미생물 모의를 위한 인공신경망 최적화)

  • Bae, Hun Kyun
    • Journal of Korea Water Resources Association
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    • v.54 no.spc1
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    • pp.1053-1060
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    • 2021
  • Current water quality monitoring systems in Korea carried based on in-situ grab sample analysis. It is difficult to improve the current water quality monitoring system, i.e. shorter sampling period or increasing sampling points, because the current systems are both cost- and labor-intensive. One possible way to improve the current water quality monitoring system is to adopt a modeling approach. In this study, a modeling technique was introduced to support the current water quality monitoring system, and an artificial neural network model, the computational tool which mimics the biological processes of human brain, was applied to predict water quality of the river. The approach tried to predict concentrations of Total coliform at the outlet of the river and this showed, somewhat, poor estimations since concentrations of Total coliform were rapidly fluctuated. The approach, however, could forecast whether concentrations of Total coliform would exceed the water quality standard or not. As results, modeling approaches is expected to assist the current water quality monitoring system if the approach is applied to judge whether water quality factors could exceed the water quality standards or not and this would help proper water resource managements.

A study on estimating the quick return flow from irrigation canal of agricultural water using watershed model (유역모델을 이용한 농업용수 신속회귀수량 산정 연구)

  • Lee, Jiwan;Jung, Chunggil;Kim, Daye;Maeng, Seungjin;Jeong, Hyunsik;Jo, Youngsik;Kim, Seongjoon
    • Journal of Korea Water Resources Association
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    • v.55 no.5
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    • pp.321-331
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    • 2022
  • In this study, we tried to present a method for calculating the amount of regression using a watershed modeling method that can simulate the hydrological mechanism of water balance analysis and agricultural water based on watershed unit. Using the soil water assessment tool (SWAT), a watershed water balance analysis was conducted considering the simulation of paddy fields for the Manbongcheon Standard Basin (97.34 km2), which is a representative agricultural area of the Yeongsan river basin. Before evaluating return flow, the SWAT was calibrated and validated using the daily streamflow observation data at Naju streamflow gauge station (NJ). The coefficient of determination (R2), Nash-Sutcliffe Efficiency (NSE), Root-Mean-Square Error (RMSE) of NJ were 0.73, 0.70, 0.64 mm/day. Based on the calibration results for three years (2015-2017), the quick return flow and the return rate compared to the water supply amount for the irrigation period (April 1 to September 30) were calculated, and the average return flow rate was 53.4%. The proposed method of this study may be used as foundation data to optimal agricultural water supply plan for rational watershed management.

Modeling of Damage Effects Caused by Ammonia Leakage Accidents in Combined Cycle Power Plant (복합화력발전소 내 암모니아 누출 사고에 의한 피해영향 모델링)

  • Eun-Seong Go;Kyeong-Sik Park;Dong-Min Kim;Young-Tai Noh
    • Journal of Korean Society of Disaster and Security
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    • v.16 no.3
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    • pp.1-15
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    • 2023
  • This study focuses on modeling the impact of ammonia leakage from the storage tank in a combined cycle power plant's flue gas denitrification facility. It employs accident impact assessments and diffusion models to determine the optimal scenarios for ammonia storage tank leakage accidents. The study considers the operating conditions of variables as standard conditions for predicting the extent of damage. The Taean combined cycle power plant is chosen as the target area, taking into account seasonal factors such as temperature, humidity, wind speed, atmospheric stability, and wind direction. By utilizing a Gaussian diffusion model, the concentration of ammonia gas at various locations is estimated to assess the potential extent of external damage resulting from a leak. The study reveals that in conditions of high temperature and stable atmosphere within the specified range, lower wind speeds contribute to increased damage to the human body due to ammonia diffusion.

Development and application of SW·AI education program for Digital Sprout Camp

  • Jong Hun Kim;Jae Guk Shin;Seung Bo Park
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.3
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    • pp.217-225
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    • 2024
  • To foster the core talents of the future, the development of diverse and substantial SW·AI education programs is required, and a systematic system that can assist public education in SW and AI must be established. In this study, we develop and combine SW·AI education modules to construct a SW and AI education program applicable to public education. We also establish a systematic education system and provide sustainable SW·AI education to elementary, middle, and high school students through 'Job's Garage Camp' based on various sharing platforms. By creating a sustainable follow-up educational environment, students are encouraged to continue their self-directed learning of SW and AI. As a result of conducting a pre-post survey of students participating in the 'Job's Garage Camp', the post-survey values improved compared to the pre-survey values in all areas of 'interest', 'understanding and confidence', and 'career aspirations'. Based on these results, it can be confirmed that students had a universal positive perception and influence on SW and AI. Therefore, if the operation case of 'Job's Garage Camp' is improved and expanded, it can be presented as a standard model applicable to other SW and AI education programs in the future.

A Study on the Patient Exposure Doses from the Panoramic Radiography using Dentistry (치과 파노라마 촬영에서 환자의 피폭선량에 관한 연구)

  • Park, Ilwoo;Jeung, Wonkyo;Hwang, Hyungsuk;Lim, Sunghwan;Lee, Daenam;Im, Inchul;Lee, Jaeseung;Park, Hyonghu;Kwak, Byungjoon;Yu, Yunsik
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.17-24
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    • 2013
  • This study estimate radiation biological danger factor by measuring patient's exposed dose and propose the low way of patient's exposed dose in panoramic radiography. We seek correcting constant of OSL dosimeter for minimize the error of exposed dose's measurement and measure the Left, Right crystalline lens, thyroid, directly included upper, lower lips, the maxillary bone and the center of photographing that indirect included in panoramic radiography by using the human body model standard phantom advised in ICRP. In result, the center of photographing's level of radiation maximum value is $413.67{\pm}6.53{\mu}Gy$ and each upper, lower lips is $217.80{\pm}2.98{\mu}Gy$, $215.33{\pm}2.61{\mu}Gy$. Also in panoramic radiography, indirect included Left, Right crystalline lens's level of radiation are $30.73{\pm}2.34{\mu}Gy$, $31.87{\pm}2.50{\mu}Gy$, and thyroid's level of measured exposed dose can cause effect of radiation biological and we need justifiable analysis about radiation defense rule and substantiation advised international organization for the low way of patient's exposed dose in panoramic radiography of dental clinic and we judge need the additional study about radiation defense organization for protect the systematize protocol's finance and around internal organs for minimize until accepted by many people that is technological, economical and social fact by using panoramic measurement.

A study on the implementation of Medical Telemetry systems using wireless public data network (무선공중망을 이용한 의료 정보 데이터 원격 모니터링 시스템에 관한 연구)

  • 이택규;김영길
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2000.10a
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    • pp.278-283
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    • 2000
  • As information communication technology developed we could check our blood pressure, pulsation electrocardiogram, SpO2 and blood test easily at home. To check our health at ordinary times is able though interlocking the house medical instrument with the wireless public data network This service will help the inconvenience to visit the hospital everytime and will save the individual's time and cost. In each house an organism data which is detected from the human body will be transmitted to the distance hospital and will be essentially applied through wireless public data network The medical information transmit system is utilized by wireless close range network It would transmit the obtained organism signal wirelessly from the personal device to the main center system in the hospital. Remote telemetry system is embodied by utilizing wireless media access protocol. The protocol is embodied by grafting CSMA/CA(Carrier Sense Multiple Access with Collision Avoidance) protocol falling mode which is standards from IEEE 802.11. Among the house care telemetry system which could measure blood pressure, pulsation, electrocardiogram, SpO2 the study embodies the ECC(electrocardiograph) measure part. It within the ECC function into the movable device and add 900㎒ band wireless public data interface. Then the aged, the patients even anyone in the house could obtain ECG and keep, record the data. It would be essential to control those who had a health-examination heart diseases or more complicated heart diseases and to observe the latent heart disease patient continuously. To embody the medical information transmit system which is based on wireless network. It would transmit the ECG data among the organism signal data which would be utilized by wireless network modem and NCL(Native Control Language) protocol to contact through wireless network Through the SCR(Standard Context Routing) protocol in the network it will be connected to the wired host computer. The computer will check the recorded individual information and the obtained ECC data then send the correspond examination to the movable device. The study suggests the medical transmit system model utilized by the wireless public data network.

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