• Proceedings of the IEEK Conference
• /
• 2003.07b
• /
• pp.831-834
• /
• 2003

본 논문에서 기술하고 있는 디블로킹 필터는 ISO/1EC 14496-2 의 디블로킹 필터링 알고리즘[1][2]을 기반으로 한다. 한 개의 레지스터 뱅크를 이용한 효율적인 데이터 스케줄링을 통해 면적과 전력 측면에서 디블로킹 필터를 사용함으로써 생기는 오버헤드를 최소화 시켰으며, CIF 급 영상을 27MHz 동작주파수에서 실시간으로 처리할 수 있도록 설계 하였다. 0.25㎛ Standard Cell Library 로 합성한 결과 총 9800 게이트로 구성 되었으며, 외부 메모리의 도움 없이 동작 시키기 위해 4.4KByte의 버퍼가 사용되었다.

• Proceedings of the IEEK Conference
• /
• 2001.06b
• /
• pp.113-116
• /
• 2001

In this paper we present a new hierarchical layout object extraction algorithm, which is based on rectangles rather than edges. The original layout data is modeled as instances connected by wires. Each polygon shape is divided into a set of rectangles and the instances and wires are extracted and recognized from those rectangles together with their connection and size information. We have applied the algorithm to actual layouts. Experiments on several standard cell library demonstrate the effectiveness of the algorithm.

• 한국정보통신설비학회:학술대회논문집
• /
• 2006.08a
• /
• pp.179-182
• /
• 2006

This paper introduce a different-type voltage-controlled oscillator (VCO) for PLL frequency synthesizer, And also the architecture of a high speed low-power-consumption CMOS dual-modulus frequency divider is presented. It provides a new approach to high speed operation and low power consumption. The proposed circuits simulate in 0.35 um CMOS standard technology.

• Journal of the Korean Chemical Society
• /
• v.14 no.1
• /
• pp.13-18
• /
• 1970

非水溶液 Ethylenediamine 中에서 水銀電極의 標準電位 및 水銀鹽化物, $HgCl_2,\;HgBr_2,\;HgI_2$의 Ion-Pair 形成恒數를, Hg電極/$HgX_2$ 또는 $HgX_2$+NaX//亞鉛아마르감 參照電極과 같은 Cell의 構成으로서 電位差法에 依하여 測定하였다.

• Proceedings of the IEEK Conference
• /
• 2003.11c
• /
• pp.365-368
• /
• 2003

In this Paper, we report a design of Serial ATA Transpor layer. The functionalities of the Serial ATA transport layer are first described on RTL via verilog. The compiled code are then fed to a synthesizer synopsys to get the actual hardware from 0.35$\mu\textrm{m}$ SAMSUNG standard cell library. The designed functionalities of this chip will be verified using test bold with FPGA equipment and ATS2 digital test equipment.

• Proceedings of the Korea Society for Simulation Conference
• /
• 1997.04a
• /
• pp.36-38
• /
• 1997

본 논문은 gate-level timed circuits의 자동 합성과 검증에 대한 것으로, 동기 회 로는 디자인을 최적화하기 위해 합성 절차가 사용된 동안 설계서에 명시된 시간 정보에 속 한 비동기 회로의 일부로서 이 시스템은 열거된 일반적인 회로 작용과 시간의 요구 조건에 대해 설계를 해석한다. 이 설계는 영향을 미치는 상태 공간을 구하기 위해 정확하고 효과적 인 시간 해석 알고리즘을 사용해 해석할 수 있는 그래픽 표현으로 자동적으로 변환된다. 이 상태공간으로부터 합성 절차는 standard-cells과 gate-arrays와 같은 반 주문형 반도체로 매핑을 용이하게 하기 위해 기본 게이트만을 사용해 어려움을 해결하는 시간에 대한 회로 유도된다.

• Journal of Chest Surgery
• /
• v.54 no.4
• /
• pp.258-262
• /
• 2021

Mediastinal lymph node dissection is an important part of lung cancer surgery that provides accurate nodal staging and may improve survival outcomes. The minimally invasive approach, such as video-assisted thoracic surgery (VATS) lobectomy for patients with non-small cell lung cancer, has become a standard operation worldwide. VATS mediastinal lymph node dissection should be thorough and accurate to ensure the completeness of lung cancer surgery. Herein, the author describes techniques for VATS mediastinal lymph node dissection.

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.261.1-261.1
• /
• 2002

The leaves of Clerodendron trichotomum Thunberg(CTL) is used in Chinese folk medicine for anti-inflammatory properties. We studied on the anti-inflammatory effects of CTL extracts in rat. mouse and Raw 264.7cell. 1 mg/kg of 30%. 60% methanol fraction of CTL and 1 mg/kg of indomethacin as the standard anti-inflammatory drug were administrated into rats, respectively. Carrageenan was injected subcutaneously to induce hind paw edema in rats. (omitted)

• The korean journal of orthodontics
• /
• v.32 no.3 s.92
• /
• pp.227-234
• /
• 2002

In order to investigate the action mechanism of protein kinase C on $K^+$ channel in osteoblastic cell, effects of phorbol 12, 13-dibutyrate on human osteoblast-like cells (G292) were studied by patch clamp technique with cell-attacked configuration. 111 this experiment, 45pS ion channel was dominant in G292 cell line according to their approximate conductances in symmetrical 140mM KCl saline at holding potential of 60mV. In torrent-voltage relationship, reversal potential was 5.5mV at the condition of potassium enriched saline in the pipette and -27 mV at the condition of standard extracellular saline In the pipette. Phorbol 12, 13-dibutyrate 10nM increased the open probability of 45pS channel and staurosporine, an inhibitor of protein kinase C, suppressed this effect. Phorbol 12,13-dibutyrate moved the reversal potential of 45pS channel to more negative potential and increased the single channel current at the same membrame potential. In order to check the activation of protein kinase C in G292 cell by phorbol 12,13-dibutyrate, western blot of protein kinase C was performed. Phorbol 12,13-dibutyrate $0.1{\mu}M$ translocated protein kinase C from cellular compartment to membrane compartment of the cell. These findings suggest that phorbol 12,13-dibutyrate, one of phorbol esters, activate 45pS channel In G292 cell and affect cell membrane potential, that regulate cellular function.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.12
• /
• pp.6191-6196
• /
• 2012

Aims and Background: Traditional chemotherapy strategies for human leukemia commonly use drugs based on cytotoxicity to eradicate cancer cells. One predicament is that substantial damage to normal tissues is likely to occur in the course of standard treatments. Obviously, it is urgent to explore therapies that can effectively eliminate malignant cells without affecting normal cells. Our previous studies indicated that ginsenoside $Rg_1$ ($Rg_1$), a major active pharmacological ingredient of ginseng, could delay normal hematopoietic stem cell senescence. However, whether $Rg_1$ can induce cancer cell senescence is still unclear. Methods: In the current study, human leukemia K562 cells were subjected to $Rg_1$ exposure. The optimal drug concentration and duration with K562 cells was obtained by MTT colorimetric test. Effects of $Rg_1$ on cell cycle were analyzed using flow cytometry and by SA-${\beta}$-Gal staining. Colony-forming ability was measured by colony-assay. Telomere lengths were assessed by Southern blotting and expression of senescence-associated proteins P21, P16 and RB by Western blotting. Ultrastructural morphology changes were observed by transmission electron microscopy. Results: K562 cells demonstrated a maximum proliferation inhibition rate with an $Rg_1$ concentration of $20{\mu}\;mol{\cdot}L^{-1}$ for 48h, the cells exhibiting dramatic morphological alterations including an enlarged and flat cellular morphology, larger mitochondria and increased number of lysosomes. Senescence associated-${\beta}$-galactosidase (SA-${\beta}$-Gal) activity was increased. K562 cells also had decreased ability for colony formation, and shortened telomere length as well as reduction of proliferating potential and arrestin $G_2$/M phase after $Rg_1$ interaction. The senescence associated proteins P21, P16 and RB were significantly up-regulated. Conclusion: Ginsenoside $Rg_1$ can induce a state of senescence in human leukemia K562 cells, which is associated with p21-Rb and p16-Rb pathways.