• 제목/요약/키워드: stability coefficient

검색결과 1,146건 처리시간 0.026초

새로운 항혈전 약물인 아스팔라톤의 전처방화 연구 (Preformulation Study of Aspalatone, a New Antithrombotic Agent)

  • 곽혜선;전인구
    • Biomolecules & Therapeutics
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    • 제8권4호
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    • pp.332-337
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    • 2000
  • Physicochemical properties of aspalatone (acetylsalicylic acid maltol ester, AM), which has been recently found to have an antithrombotic effect, were studied in terms of solubility, dissolution, partition coefficient (Pc) and stability. The solubility of AM at 37$^{\circ}C$ was about 1.2 mg/ml and the P$_{c}$ value for n-octanol/water and chloroform/water was 11.4 and 382.6, respectively. Dissolution rates of AM at pH 1.2 and 6.8 were more than 80% within 30 min. The degradation of AM followed apparent first-order kinetics, and was dependent on temperature, pH and ionic strength. From the pH-rate profile, the optimal pH was found to be at around 4.0. Half-lives at pH 1.2 and 6.8 were 33.5 and 44.4 hr, respectively. The degradation rate of AM at pH 1.2 was somewhat faster than that of aspirin, but at pH 7.0, the degradation rate of AM was slower than that of aspirin.n.

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CDM 방법을 사용한 선형시스템의 신뢰성 있는 소음제어기 설계 (Design of A Noise Controller for A Linear system using the CDM)

  • 김정환;정태진;이상철;정양웅;정찬수
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1998년도 하계학술대회 논문집 B
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    • pp.455-457
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    • 1998
  • This paper designs a noise controller for the small cavity using Coefficient Diagram Method(CDM). In the small cavity system, there exist nonlinear characteristics such as uncertain-time delay and parameter variation. In the controller design of nonlinear system with uncertainty need to the higher order controller or complexity computation. The coefficient diagram is convenient implementation of the control system design method, that is utilized as a vehicle to collectively express the important features of the system and an improved version Kessler's standard form and the Lipatov stability condition of a constitutes the theoretical basis. Simultaneously, it is provided a desired specification, such as the robustness, the stability, faster response, and lower order controller. A simulation of the system with the proposed controller shows sufficient noise cancelation in small cavity.

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On thermal stability of plates with functionally graded coefficient of thermal expansion

  • Bousahla, Abdelmoumen Anis;Benyoucef, Samir;Tounsi, Abdelouahed;Mahmoud, S.R.
    • Structural Engineering and Mechanics
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    • 제60권2호
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    • pp.313-335
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    • 2016
  • In this article, a four-variable refined plate theory is presented for buckling analysis of functionally graded plates subjected to uniform, linear and non-linear temperature rises across the thickness direction. The theory accounts for parabolic distribution of the transverse shear strains, and satisfies the zero traction boundary conditions on the surfaces of the plate without using shear correction factor. Young's modulus and Poisson ratio of the FGM plates are assumed to remain constant throughout the entire plate. However, the coefficient of thermal expansion of the FGM plate varies according to a power law form through the thickness coordinate. Equilibrium and stability equations are derived based on the present theory. The influences of many plate parameters on buckling temperature difference such ratio of thermal expansion, aspect ratio, side-to-thickness ratio and gradient index will be investigated.

이트리아가 첨가된 프라세오디뮴계 산화아연 바리스터의 안정성에 관한 연구 (A Study on the Stability of Praseodymium-Based Zinc Oxide Varistor with Tittria Additives.)

  • 남춘우;박춘현
    • 한국전기전자재료학회논문지
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    • 제11권10호
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    • pp.842-848
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    • 1998
  • The stability of paraseodymium-based zinc oxide varistor consisting of Zn-Pr-Co-Cr-Y oxide was investigated according to yttria additives under different stress conditons, such as 0.8V\ulcorner\ulcorner/373K/12h and 0.85V\ulcorner\ulcorner/393K/12h. Wholly, all varistor after the stress showed nearly symmetric and stable I-V characteristics. Particularly, in the case of 2.0mol% and 4.0mol% yttria-added varistor showing a good I-V characteristics, the varation rate of varistor voltage were less 1% and that of nonlinear coefficient were about degree of 5%, and what is remarkable, leakage current with increasing stress time during the applied stress was almost constant. It the light of these facts, it is estimated that varistor constituents having 2.0mol% and 4.0mol% yittria, respectively, will be utilized to various application fields.

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Development of a meshless finite mixture (MFM) method

  • Cheng, J.Q.;Lee, H.P.;Li, Hua
    • Structural Engineering and Mechanics
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    • 제17권5호
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    • pp.671-690
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    • 2004
  • A meshless method with novel variation of point collocation by finite mixture approximation is developed in this paper, termed the meshless finite mixture (MFM) method. It is based on the finite mixture theorem and consists of two or more existing meshless techniques for exploitation of their respective merits for the numerical solution of partial differential boundary value (PDBV) problems. In this representation, the classical reproducing kernel particle and differential quadrature techniques are mixed in a point collocation framework. The least-square method is used to optimize the value of the weight coefficient to construct the final finite mixture approximation with higher accuracy and numerical stability. In order to validate the developed MFM method, several one- and two-dimensional PDBV problems are studied with different mixed boundary conditions. From the numerical results, it is observed that the optimized MFM weight coefficient can improve significantly the numerical stability and accuracy of the newly developed MFM method for the various PDBV problems.

인간 동력 항공기의 2차원 익형을 이용한 정적 안정성 및 동적 안정성 해석

  • 고동재;안영민
    • EDISON SW 활용 경진대회 논문집
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    • 제5회(2016년)
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    • pp.593-597
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    • 2016
  • 항공기의 비행 안정성을 판별하기 위해서는 정적(static)안정성과 동적(dynamic)안정성을 모두 고려해야 한다. 본 연구는 EDISON_CFD의 KFLOW_EDISON_2D3DOF, 2D_Com_P해석자를 이용해 2차원익형의 정적(static)계수와 동적(dynamic)계수를 구해 항공기 전체형상의 정적 안정성 및 동적 안정성을 분석하였다. 그 중 2015년도 인간 동력 항공기대회 건국대학교 참가 기체를 예시로 연구를 진행하였다. 주익 익형 SG6043과 미익 익형 NACA0012을 EDISON_CFD를 이용하여 각 익형의 모멘트계수를 구하고 그 결과값을 이용하여 기체의 무게중심에 대한 각 익형의 감쇠계수를 계산하였다. 그리고 주익과 미익의 면적비율과 코드길이의 비율을 고려해 전체 항공기형상의 안정성과 비행 형태를 분석하였다.

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점용접된 구조물의 좌굴하중해석 (Bucking Load Analysis of Spot-Welded Structures)

  • 이현철;심재준;안성찬;한근조
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 1999년도 추계학술대회논문집
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    • pp.265-272
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    • 1999
  • This stability of a plate structure is very crucial problem which results in wrinkle and bucking. In this study, the effect of the pattern of spot-welding points of the two rectangular plates on the compressive and shear bucking load is studied with respect to the thickness, aspect ratio of plates and number of welding spots. Buckling coefficient of the plate not welded was compared with that of two plates with various thickness to extract the effect of thickness. The effect of number of welding spots are studied in two directions, longitudinal and transverse directions. The conclusions obtained were that the reinforcement effect was maximized when the aspect ratio was close to 1.75 at compressive load condition and that the effect of number of welding spots in transverse direction was larger than that in longitudinal direction at shearing load condition.

RecurDyn을 이용한 동적 해석 시 마찰모델에 따른 적분 안정성 및 정확성 연구 (Study on the Integration Stability and the Accuracy of Some Friction Models for the Dynamic Analysis Using Recurdyn)

  • 유홍희;이준희
    • 한국소음진동공학회논문집
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    • 제18권11호
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    • pp.1111-1117
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    • 2008
  • During the dynamic analysis of a system, the Coulomb friction law is emploved to calculate the friction force. Since the static friction coefficient is only employed during the zero relative velocity, it is impractical to employ the coefficient during the dynamic analysis. To calculate the static friction force, therefore, some friction models have been developed. In this study, the integration stability and the accuracy of the models are investigated with some numerical examples. The effect of time step size during the numerical integration is also investigated. The numerical study shows that the friction model employed for most commercial codes is not as good as the one proposed in this study.

Metaheuristic Optimization Techniques for an Electromagnetic Multilayer Radome Design

  • Nguyen, Trung Kien;Lee, In-Gon;Kwon, Obum;Kim, Yoon-Jae;Hong, Ic-Pyo
    • Journal of electromagnetic engineering and science
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    • 제19권1호
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    • pp.31-36
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    • 2019
  • In this study, an effective method for designing an electromagnetic multilayer radome is introduced. This method is achieved by using ant colony optimization for a continuous domain in the transmission coefficient maximization with stability for a wide angle of incidence in both perpendicular and parallel polarizations in specific X- and Ku-bands. To obtain the optimized parameter for a C-sandwich radome, particle swarm optimization algorithm is operated to give a clear comparison on the effectiveness of ant colony optimization for a continuous domain. The qualification of an optimized multilayer radome is also compared with an effective solid radome type in transmitted power stability and presented in this research.

서로 다른 물성치로 이루어진 다공 세라믹 연소기 속에서의 예혼합화염 연소에 대한 수치해석 연구 (Numerical Study of Premixed Combustion within a Porous Ceramic Burner of Different Ceramic Properties)

  • 임인권
    • 한국연소학회지
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    • 제2권1호
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    • pp.1-8
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    • 1997
  • Premixed combustion within porous ceramic media is numerically studied to understand burning characteristics and to find best configurations for burner implementations. Among many parameters, critical to burner performance, flame location and extinction coefficient are selected as major parameters for this study. The flame structure and burner performance with respect to these two parameters are observed. In the study, it is found that the location of flame is the most important in porous burner operation since it affects the rate of heat transfer and flame structure. Stability of the flame within the porous ceramic burner is discussed with respect to the flame location. It is found that to obtain high radiative output, the flame should be located downstream section of the burner. But the flame is to be unstable at most of downstream section except near the exit plane. To overcome this problem, new porous ceramic burner, using different ceramic properties in one burner instead of single property ceramic, is made and tested. With a combination of ceramics of high extinction coefficient at upstream and another material of low extinction coefficient at downstream of the burner, the flame can be stabilized at wider region of the burner with higher radiative output compared to the original burner configuration.

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