• Title/Summary/Keyword: spraying method

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Formulation of Erythromycin Enteric-coated Pellets (에리스로마이신 장용성 펠렛의 제제 설계)

  • 이승우;박은석;지상철
    • YAKHAK HOEJI
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    • v.39 no.6
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    • pp.593-599
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    • 1995
  • Erythromycin was formulated as enteric-coated pellets in order to reduce degradation in stomach and gastromtestmal irritation, and to maximize the absorption in intestine followmg its oral administration. Core pellets were prepared using fluid-bed granulator with two different methods (powder layering and solvent spraying) and enteric-coated with two different coating polymers (HPMCP and Eudragit E30D). Physical characteristics md dissolution rates of core pellets and enteric-coated pellets were evaluated to optimize the formulation. Powder layering method resulted in shorter initial dissolution time than solvent spraying method, but physicochmical properties of the product were worse than solvent spraying method with respect to hardness, ftiability and density. The dissolution rate of the drug was increased with the addition of surfactants, showing concentration-dependence. The scanning electron microscopic observation of pellets revealed significant differences on the surface appearances prepared with solvent spraying method. The core pellet made with powder layering method had crystals on the surface, which resulted in poor physical properties of the pellets. The dissolution profiles of erythromycin pellets coated with HPMCP or Eudragit L30D were close to that of commercially available erythromycin enteric-coated product.

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Development for Finishing Method of Concrete Structures Applying Metal Spraying System (금속용사 시스템을 이용한 콘크리트 구조물의 마감공법 개발)

  • 이한승
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.11a
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    • pp.1225-1228
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    • 2001
  • The purpose of this study is to develop for finishing method of concrete structures applying metal spraying system. In the experiments, the pull out tests were conducted using the specimen which was applied by various surface treatment of concrete substrate. As a result, it was confirmed that the adhesion strength of metal spray was effected by surface condition of concrete and the construction of primer or the coarse surface agent to the concrete substrate is very effective to the new finishing method of concrete for the metal spraying system.

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The Control of Anti-slip Characteristics of Packaging Paper Using Nano-colloidal Silica (나노 콜로이달 실리카를 이용한 포장용지의 미끄럼특성 제어)

  • Lee, Won-No;Kim, Hyoung-Jin
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.37 no.3
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    • pp.33-40
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    • 2005
  • In this study, a nano-colloidal silica sol was applied to control the anti-slip property by spraying on kraft paper. Two kinds of nano-colloidal silica sol which have cationic and anionic charge were applied in kraft paper, and the friction and physical strength properties of kraft paper were investigated. The application of colloidal silica sol on wet web in wet-end process by spraying method was tried to improve the friction property and to avoid the general problems of machine contaminations caused by the scattering of sprayed silica particles in dryer part. The physical properties of sheet were also improved by the application of wet web spraying method, and the optimum conditions of wet web spraying operation were closely related with the conditions of pH and electrical charge of wet web and silica sol.

An Experimental Study for Establishment of On-Site Quality Control of Repair Material by the mechanized construction (기계화시공에 의한 보수재료의 현장품질관리확립을 위한 실험적 연구)

  • Cho Bong Suk;Jang Jae Bong;Kim Yong Ro;Kang Suk Pyo;Hong Sung Yun;Kim Moo Han
    • Proceedings of the Korea Concrete Institute Conference
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    • 2004.05a
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    • pp.160-163
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    • 2004
  • In domestic, various repair materials and method systems to keep up with these reinforced concrete deteriorated due to salt damage, carbonation, chemical decay et. developed and applied. However, on-site quality control of various repair materials and method systems isn't achieved desirably because it is depend completely on a men of experience' opinions above all else regardless of various on-site environments. In this background, mock up test with due regard to real on-site environments was performed to secure fundamental data for establishment of desirable on-site quality control. Mock up test using repair mortar analyzed from angles of construction methods, mechanical spraying pressures, W/M. Construction methods were designed manpower method and spraying method, spraying pressures were designed 32, 42, 52 psi, W/M were designed 14.4, 15.4, $16.4\%$. And compressive strength, Chloride ion diffusion coefficient, bond strength, SEM. of mock up test specimens were evaluated. In conclusion, we confirmed excellency of mechanical spraying pressures, fined extremely excellency of condition of spraying pressure 42 ps, W/M $14.4\%$ within this study. therefore the results of this study will be useful to provide fundamental data for establishment of desirable on-site quality control.

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Mechanical Properties of Metal/Ceramic FGM made by Thermal Spraying Method (용사법에 의해 제작된 금속/세라믹 경사기능 재료의 기계적 특성)

  • Kim, Y.S.;Nam, K.W.;Kim, H.S.;Oh, M.S.;Kim, K.S.
    • Journal of Power System Engineering
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    • v.2 no.3
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    • pp.41-48
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    • 1998
  • This study was aimed at development of fabrication process of functionally graded materials(FGM), consisting of metal and ceramic by thermal spraying method. NiCrAIY/$Al_2O_3$ FGM were made by using plasma spraying onto the SS400 carbon steel substrate. And mechanical properties such as microhardness, thermal shock resistance and adhesive strength of the coating layer were investigated. Adhesive strength was evaluated by acoustic emission method. It was resulted that NiCrAIY/$Al_2O_3$ FGM made by thermal spraying method showed excellent thermal shock resistance and adhesive strength compared to the other lamellar structures of sprayed coatings and that AE is useful tool to evaluate the defect of thermal sprayed coating layer.

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A Study on Pressure Drop and Flow Rate of High Viscosity Paint (고점도 도료의 압력손실 및 분사량에 관한 연구)

  • Baek, J.J.;Chung, M.K.;Shin, C.S.;Baek, K.K.
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.786-791
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    • 2003
  • We have studied on the main causes of pressure drop in the paint hose under the spraying with airless spray pump and suggest calculation method for selecting the optimum pressure drop during the spraying. Among many factors contributing the pressure drop during the airless spraying procedure of paint, some of the key factors and the correct method for checking pressure loss between airless pump and spray gun are addressed. We have developed pressure loss calculation method which depending on hose length and diameter, viscosity and flow rate in the painting hose during the spraying. also we have developed calculation equation for the expected spray tip flow rate which depending on pressure and specific gravity and tip size.

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Development of A Boom Sprayer for Effective Pest-and-Disease Control on Densed Paddy Stems (수도(水稻) 기부(基部) 방제용(防除用) 붐-형(型) 주간(株間) 살포(撒布) 장치(裝置) 개발(開發)에 관(關)한 연구(硏究))

  • Chung, Chang Joo;Chang, Young Chang
    • Journal of Biosystems Engineering
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    • v.10 no.1
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    • pp.13-23
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    • 1985
  • Spraying method from the paddy-field levee is known to give insufficient penetration of the spray droplets to the rice stem of the densely grown plants, which is generally encountered at the last stage of rice growth. This study was intended to investigate the spraying system to solve this existing problem. As an approach, it was attempted to develop the boom-with-nozzle, between-the-row application system. Several types of nozzles and their different arrangements in the boom were tested in the field to measure the penetration-reaching distance and the uniformity of spray droplet distribution. The results of the study are summarized as follows: 1. Field experiments by the spraying method from the paddy-field levee showed to have practically no penetration of the spray droplets to the portion of the plant stem with the normal flow volume generally applied and thus need for improving present spraying method. 2. It was found that, considering both the uniformity of the spray droplet distribution and performance rate, the most efficient type of nozzle in the between-the-row boom-type spraying system was one that has core-insert hollow-cone with some clearance between the cone and tip. 3. When tested by applying the spraying method of between-the-row, the nozzle pressure did not affect the uniformity of spray droplet distribution. However, the nozzle pressure had a positive effect on the penetrating-reaching distance of the facing side of the rice stem and did not affect much on that of the opposite face of the stem. It was also found that the maximum pressure to affect the penetration-reaching distance was about $10kg/cm^2$. 4. The uniformity of the spray droplet distribution in the between-the-row system was greatly affected by the height and orientation of the nozzles in the boom. Based on experimental work for the different type of the boom-with-nozzle arrangements, it is recommended that the position of nozzle is set at about 0.45 m above the ground and two nozzles in the boom are oriented to be faced with each other with some angle such that the droplet stream from the nozzle would not directly face with each other.

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Characterizations of Two-step Matrix Application Procedures for Imaging Mass Spectrometry

  • Shimma, Shuichi
    • Mass Spectrometry Letters
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    • v.6 no.1
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    • pp.21-25
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    • 2015
  • In this paper, I describe the importance of matrix spraying conditions in imaging mass spectrometry (IMS) to obtain successful imaging results. My developed matrix application methodology, which is a "two-step matrix application" sequentially combined with matrix sublimation and spraying matrix solution can provide high reproducibility and high ion yield compared with a conventional direct spraying method. However, insufficient IMS results were obtained occasionally despite the two-step method. Therefore, I wanted to characterize the methodology to continuously provide high quality data. According to my results, the sublimation time was not a strict parameter, and the most important step was the first spraying condition. This means that the extraction conditions from the tissue section and co-crystallization of the matrix were the most important factors.

Effect of Air-Phase Germination with Anion Radiation and Water-Spraying on Germination Ratio, Sprout Growth, and GABA Contents of Germinated Brown Rice

  • Lim, K.T.;Chung, J.H.;Hong, J.H.;Kim, J.H.;Lee, E.T.;Im, A.L.
    • Agricultural and Biosystems Engineering
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    • v.7 no.1
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    • pp.42-47
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    • 2006
  • The objective of this study was to investigate the effects of air-phase germination with water-spraying and anion stimuli on germination ratio, sprout growth and ${\gamma}$-aminobutyric acid (GABA) of brown rice. Air-phase germination method with intermittent spraying water improved germination ratio and sprout growth by about 100% compared with the conventional water-soaking method. Anion radiation was applied during the germination process and improved the germination ratio, sprout growth and color quality of the germinated brown rice. Germination ratio and sprout growth were improved up to 9% with anion radiation, and its brightness was higher than brown rice germinated with no anion radiation. The air-phase germination with water-spraying improved the GABA content of germinated brown rice by about 8-9 times compared with that of brown rice.

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Effects of Powder Melting Degree on Microstructural Features of Plasma Sprayed Y2O3 Coating (플라즈마 제트에서의 분말 용융특성에 따른 Y2O3 코팅층의 미세조직 형성거동)

  • Kang, Sang-Woon;Baik, Kyeong-Ho
    • Korean Journal of Materials Research
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    • v.26 no.5
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    • pp.229-234
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    • 2016
  • In this study, the degree of particle melting in $Y_2O_3$ plasma spraying and its effects on coating characteristics have been investigated in terms of microstructural features, microhardness and scratch resistance. Plasma sprayed $Y_2O_3$ coatings were formed using two different powder feeding systems: a system in which the powder is fed inside the plasma gun and a system in which the powder is fed externally. The internal powder spraying method generated a well-defined lamellae structure that was characterized by a thin porous layer at the splat boundary and microcracks within individual splats. Such micro-defects were generated by the large thermal contraction of splats from fully-molten droplets. The external powder spraying method formed a relatively dense coating with a particulate deposition mode, and the deposition of a higher fraction of partially-melted droplets led to a much reduced number of inter-splat pores and intra-splat microcracks. The microhardness and scratch resistance of the $Y_2O_3$ coatings were improved by external powder spraying; this result was mainly attributed to the reduced number of micro-defects.