• 제목/요약/키워드: sprA

검색결과 238건 처리시간 0.034초

농지평가에 있어서 토질등급의 이용과 적용 ; 사우스다코다주의 사례 (Application and Use of Land Quality Ratings in the Valuation of Agricultural Land:An Evaluation of the South Dakota Experience)

  • ;정덕영;심호영
    • 한국토양비료학회지
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    • 제37권4호
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    • pp.288-291
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    • 2004
  • 미국의 South Dakoda주에서는 농지 평가를 위하여 토양생산등급체계와 토양분류를 점토하였다. 현재 그리고 앞으로 우리가 직면할 환경과 농업토양과 관련한 문제에 대하여, 우리가 실질적으로 쉽게 획득할 자료는 많지 않다. 그러므로 적절한 평가방법을 수행하고 자료를 발굴하기 하기 위하여 다양한 기술을 개발적용하고, 그리고 필요를 확인하기 위하여 정부와 민간분야의 의뢰인들이 같이 연구하였다. 세무관련자, 부동산평가인 등이 토양생산등급체계를 토지가격작업에 적용하였다. 그리고 경제학자들은 이를 농지의 이익과 제한요인과 함께 검토하였다 농지의 실질적 가격은 토지로터 안전농산물을 생산하는 것 외에 농업활동에 의한 환경개선이나 보호에 대한 농업의 전망을 충족시키는가에 의해 결정되어야 한다. 그러므로 우리는 모두 토양, 물, 대기가 농업이나 산림에 미치는 영향력을 이해하는 것이 더 중요하다.

Characterization of binding specificity using GST-conjugated mutant huntingtin epitopes in surface plasmon resonance (SPR)

  • Cho, Hang-Hee;Kim, Tae Hoon;Kim, Hong-Duck;Cho, Jae-Hyeon
    • 한국동물위생학회지
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    • 제44권4호
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    • pp.185-194
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    • 2021
  • Polyglutamine extension in the coding sequence of mutant huntingtin causes neuronal degeneration associated with the formation of insoluble polyglutamine aggregates in Huntington's disease (HD). Mutant huntingtin can form aggregates within the nucleus and processes of neurons possibly due to misfolding of the proteins. To better understand the mechanism by which an elongated polyglutamine causes aggregates, we have developed an in vitro binding assay system of polyglutamine tract from truncated huntingtin. We made GST-HD exon1 fusion proteins which have expanded polyglutamine epitopes (e.g., 17, 23, 32, 46, 60, 78, 81, and 94 CAG repeats). In the present emergence of new study adjusted nanotechnology on protein chip such as surface plasmon resonance strategy which used to determine the substance which protein binds in drug discovery platform is worth to understand better neurodegenerative diseases (i.e., Alzheimer disease, Parkinson disease and Huntington disease) and its pathogenesis along with development of therapeutic measures. Hence, we used strengths of surface plasmon resonance (SPR) technology which is enabled to examine binding specificity and explore targeted molecular epitope using its electron charged wave pattern in HD pathogenesis utilize conjugated mutant epitope of HD protein and its interaction whether wild type GST-HD interacts with mutant GST-HD with maximum binding affinity at pH 6.85. We found that the maximum binding affinity of GST-HD17 with GST-HD81 was higher than the binding affinities of GST-HD17 with other mutant GST-HD constructs. Furthermore, our finding illustrated that the mutant form of GST-HD60 showed a stronger binding to GST-HD23 or GST-HD17 than GST-HD60 or GST-HD81. These results indicate that the binding affinity of mutant huntingtin does not correlate with the length of polyglutamine. It suggests that the aggregation of an expanded polyglutamine might have easily occurred in the presence of wild type form of huntingtin.

직접속도 피드백을 이용한 보의 능동진동제어 (Active Vibration Control of a Beam using Direct Velocity Feedback)

  • 이영섭
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2004년도 춘계학술대회논문집
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    • pp.587-592
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    • 2004
  • Direct velocity feedback (DVFB) control is known that it offers an unconditional stability with very high performance when the control strategy is applied at a point collocated sensor and actuator pair, because the sensor-actuator pair has strictly positive real (SPR) property. In this paper, two types of collocated sensor-actuator pairs are considered for practical active vibration control of a structure. They are a point collocated sensor-actuator pair and a point sensor-distributed actuator pair. Both pairs with DVFB sho robust stability and performance. It is noted that the collocated point sensor-actuator ultimately acts as a 'skyhook' damper, but the point sensor-distributed actuator pair with DVFB acts as a 'skyhook' rotational dmaper pair.ational dmaper pair.

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보의 능동진동제어을 통한 직접속도 피드백의 적용성 연구 (Active Vibration Control of a Beam Using Direct Velocity Feedback)

  • 이영섭
    • 한국소음진동공학회논문집
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    • 제14권7호
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    • pp.619-625
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    • 2004
  • Direct velocity feedback (DVFB) control is known that it offers an unconditional stability with very high performance when the control strategy is applied at a point collocated sensor and actuator pair. because the sensor-actuator pair has strictly positive real (SPR) property In this paper, two types of collocated sensor-actuator pairs are considered for practical active vibration control of a structure. They are a Point collocated sensor-actuator pair and a point sensor-distributed actuator pair. Both pairs with DVFB show robust stability and performance. It is noted that the collocated point sensor-actuator ultimately acts as a “skyhook” damper, hut the point sensor-distributed actuator pair with DVFB acts as a “skyhook” rotational damper pair.

Surface Plasmon Enhanced Photoluminescence of Rhodamine B Confined in SBA15

  • Dinakaran, K.;Chandramohan, A.;Venkatesan, M.R.;Devaraj, S.;Devi, V.;Alagar, M.
    • Bulletin of the Korean Chemical Society
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    • 제32권11호
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    • pp.3861-3864
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    • 2011
  • Rhodamine B dye (RB) has been introduced into the mesoporous silica (SBA15) and Ag anchored mesoporous silica by applying solution impregnation method. Surface treatment of SBA15 with 3-aminopropyltrimethoxysilane (APTMS) facilitates selective anchoring of the RB molecules on SBA15. The photoluminescence spectra of RB confined within SBA15 indicates higher emission intensity, than that of the RB solid, particularly in the presence of Ag nanoparticles. The significant enhancement in photoluminescence intensity is attributed to the local enhancement of the optical fields near the molecules by interactions with silver plasmons.

A modified model reference adaptive system for the speed identification of induction motors

  • Hur, Namho;Hong, Kichul;Nam, Kwanghee
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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    • pp.427-431
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    • 1996
  • The MRAS proposed by Schauder [8] is modified to improve robustness to the change of load torque and/or the variation of the stator resistance. The difference between the voltage and the current model is fed into the current model via proportional and integral gains. In order to generalize the MRAS, supposing that the rotor speed is time varying, we add a compensating term to the current model. It does not alter the Popov's integral inequality condition. Also, the asymptotic stability of the modified MRAS (MMRAS) is shown with the stability proof technique as in the original paper. By the simulation works, it is verified that the MMRAS obtains improved performance than the original MRAS.

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Biochemical Application of IgG Fc-binding peptide: From Biochip to Targeted Nano Carrier

  • Chung, Sang Jeon
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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    • pp.84-84
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    • 2013
  • FcBP consisting of 13 amino acids specifically binds to Immunoglobulin G Fc domain. Initially, we utilized this peptide for preparation of antibody chip as a PEG composite for enhanced solubility. After then, the peptide conjugate was immobilized on agarose resin, resulting in highly efficient affinity column for antibody purification. The efficiency was comparable to commercial Protein A column. Recently, this peptide was conjugated with cell penetratingpeptide (CPP) on a backbone of GFP, affording antibody transducer, which carries antibody into live cells by simple mixing of antibody and the transducer in cell culture media. Antibody transduction into cells was monitored by live cell imaging. More recently, the FcBP was fused to ferritin cage, which consists of 24 ferritin protein molecules. The FcBP-ferritin cage showed greatly increased binding affinity to human IgG. Its binding was analyzed by QCM and SPR analysis. Finally, it was selectively delivered by Herceptin to SKBR3, a breast cancer cell, over MCF10A, non-tumorigenic cells.

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A Semi-graphical Analysis on the Sublattice Anisotropy of a Two Sublattice System with Uniaxial Anisotropy: Application to Pr2Fe14B

  • Kim, Y.B.;Jin-Han-Min
    • Journal of Magnetics
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    • 제3권3호
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    • pp.74-77
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    • 1998
  • A method to analyze the anisotropy constants of a two sublattice system with uniaxial anisotropy has been investigated by extending the Sucksmith and Thompson's method to higher order anisotropy terms. Using the method, a set of anisotropy constants for Pr-sublattice of $Pr_2Fe_{14}B at 4.2K has been obtained as K_{1Pr}=5210 J/kg, K_{2Pr}=-7200 J/kg, K_{3Pr}=-770 J/kg, K_{4Pr}=4940 J/kg and K_{SPr}=700 J/kg for N_{PrFe}=2.2 T/Am^2kg^{-1}.$ The magnetization calculated by an energy minimum method by using the sublattice anisotropy constants well reproduced the experimental results and satisfied the simulation assumptions.

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출력관측 오차의 필터링을 이용한 비선형 계통의 강인한 신경망 관측기 설계 (Robust Adaptive Neural-Net Observer for Nonlinear Systems Using Filtering of Output Estimation Error)

  • 박장현;윤필상;박귀태
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 하계학술대회 논문집 D
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    • pp.2320-2322
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    • 2001
  • This paper describes the design of a robust adaptive neural-net(NN) observer for uncertain nonlinear dynamical system. The Lyapunov synthesis approach is used to guarantee a uniform ultimate boundedness property of the state estimation error, as well as of all other signals in the closed-loop system. Especially, for reducing the dynamic oder of the observer, we propose a new method in which no strictly positive real(SPR) condition is needed with on-line estimation of weights of the NNs. No a priori knowledge of an upper bounds on the uncertain terms is required. The theoretical results are illustrated through a simulation example.

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Polygonal finite element modeling of crack propagation via automatic adaptive mesh refinement

  • Shahrezaei, M.;Moslemi, H.
    • Structural Engineering and Mechanics
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    • 제75권6호
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    • pp.685-699
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    • 2020
  • Polygonal finite element provides a great flexibility in mesh generation of crack propagation problems where the topology of the domain changes significantly. However, the control of the discretization error in such problems is a main concern. In this paper, a polygonal-FEM is presented in modeling of crack propagation problems via an automatic adaptive mesh refinement procedure. The adaptive mesh refinement is accomplished based on the Zienkiewicz-Zhu error estimator in conjunction with a weighted SPR technique. Adaptive mesh refinement is employed in some steps for reduction of the discretization error and not for tracking the crack. In the steps that no adaptive mesh refinement is required, local modifications are applied on the mesh to prevent poor polygonal element shapes. Finally, several numerical examples are analyzed to demonstrate the efficiency, accuracy and robustness of the proposed computational algorithm in crack propagation problems.